National Toxicology Program

National Toxicology Program

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First listed in the Second Annual Report on Carcinogens (1981) Also known as PCBs or chlorodiphenyls (Cl) x (Cl) y Polychlorinated biphenyls (number of chlorine atoms [x + y] = 1-10) Carcinogenicity Polychlorinated biphenyls (PCBs) are reasonably anticipated to be human carcinogens based on sufficient evidence of carcinogenicity from studies in experimental animals. Not all PCB mixtures caused tumors in experimental animals. Cancer Studies in Experimental Animals Oral exposure to PCBs caused liver ...
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0 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) http://ntp.niehs.nih.gov/go/16325 Abstract for TR-530 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) and ...
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(CAS NO. 57465-28-8) AND 2,2N,4,4N,5,5N-HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS (GAVAGE ... STUDIES OF A BINARY MIXTURE OF 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) AND 2,2N,4,4N,5,5N-HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS ... in Female Rats in the 2-Year Gavage Study of a Binary Mixture of PCB 126 and PCB 153: Groups 1, 2, 3, 5, 7 . . . . . . . . . . . . . . . . ...
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1 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508-00-6) http://ntp.niehs.nih.gov/go/16331 Abstract for TR-531 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508-00-6) Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) and 2,3',4,4',5-Pentachlorob...
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(CAS NO. 57465-28-8) AND 2,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS (GAVAGE STUDIES) ... STUDIES OF A BINARY MIXTURE OF 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) AND 2,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS (GAVAGE ... in Female Rats in the 2-Year Gavage Study of a Binary Mixture of PCB 126 and PCB 118 . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
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TEF Evaluation (PCB Mixture; PCB 126/PCB 118) M970041 Link to Data Search (Data is not available for all studies.) Overviews of NTP Protocols http://ntp.niehs.nih.gov/go/ts-m970041 TEF Evaluation (PCB Mixture; PCB 126/PCB 118) - M970041 CASRN: TEFPCBMIX Synonyms/Common Names: PCB MIXTURE (TOXIC EQUIVALENCY FACTOR EVALUATION) TOXIC EQUIVALENCY FACTOR EVALUATION (PCB MIXTURE (PCB 126/PCB 118)) Secondary: 31508-00-6 - 2,3',4,4',5-Pentachlorobiphenyl 57465-28-8 - 3,3,4,4,5-Pentachlorobiphenyl (PCB ...
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TEF evaluation (PCB 118) M030022 Link to Data Search (Data is not available for all studies.) Chemical Properties Toxicity Effects (HSDB) Overviews of NTP Protocols http://ntpfuture.niehs.nih.gov/go/ts-m030022 TEF evaluation (PCB 118) - M030022 CASRN: 31508-00-6 Formula: C12-H5-Cl5 Synonyms/Common Names: PCB-118 (TOXIC EQUIVALENCY FACTOR EVALUATION) TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 118) TOXIC EQUIVALENCY FACTOR EVALUATION (2,3',4,4',5-PENTACHLOROBIPHENYL) Known Uses: Polychlorinated ...
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29 - 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) http://ntp.niehs.nih.gov/go/20264 Abstract for TR-529 - 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) Toxicology and Carcinogenesis Studies of 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in Female Harlan Sprague-Dawley Rats (Gavage Studies) ... the chronic toxicity and carcinogenicity of DLCs and structurally related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...
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TEF transgenics (PCB 126 / PECDF mixture) M020020 Link to Data Search (Data is not available for all studies.) Overviews of NTP Protocols http://ntpfuture.niehs.nih.gov/go/ts-m020020 TEF transgenics (PCB 126 / PECDF mixture) - M020020 CASRN: TEFTGMIXTURE Synonyms/Common Names: PCB 126/PECDF MIXTURE (TEF TRANSGENICS) TEF TRANSGENICS (3,3',4,4',5-PENTACHLOROBIPHENYL/2,3,4,7,8-PENTACHLORODIBENZOFURAN MIXTURE) Secondary: 57465-28-8 - 3,3,4,4,5-Pentachlorobiphenyl (PCB 126) 57117-31-4 - ...
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All Long-Term Reports » Abstract for TR-520 - 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) http://ntp.niehs.nih.gov/go/9301 Abstract for TR-520 - 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Toxicology and Carcinogenesis Studies of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage ... carcinogenicity of DLCs and structurally-related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ***** 3,3',4,4',5-Pentachlorobiphenyl (PCB ...
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TEF transgenics (PCB 126) M020018 Link to Data Search (Data is not available for all studies.) Chemical Properties Toxicity Effects (HSDB) Overviews of NTP Protocols http://ntpfuture.niehs.nih.gov/go/ts-m020018 TEF transgenics (PCB 126) - M020018 CASRN: 57465-28-8 Formula: C12-H5-Cl5 Synonyms/Common Names: PCB 126 (TEF TRANSGENICS) TEF TRANSGENICS (3,3',4,4',5 PENTACHLOROBIPHENYL) Known Uses: Special evaluation of relative potency factors for papilloma induction by dioxin-like compounds in ...
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9 - 2,3',4,4',5-Pentachlorobiphenyl (PCB 118)(CASRN 31508-00-6) http://ntp.niehs.nih.gov/go/33539 Abstract for TR-559 - 2,3',4,4',5-Pentachlorobiphenyl (PCB 118)(CASRN 31508-00-6) TR-559 Toxicology and Carcinogenesis Studies of 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CAS No. 31508-00-6) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Link ... evaluate the chronic toxicity and carcinogenicity of DLCs and structurally related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...
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TEF evaluation (Binary mixture; PCB 126/PCB 153) M960055 Link to Data Search (Data is not available for all studies.) Overviews of NTP Protocols http://ntp.niehs.nih.gov/go/ts-m960055 TEF evaluation (Binary mixture; PCB 126/PCB 153) - M960055 CASRN: TEFBINARYMIX Formula: N/A Synonyms/Common Names: BINARY MIXTURE (TOXIC EQUIVALENCY FACTOR EVALUATION) TOXIC EQUIVALENCY FACTOR EVALUATION (BINARY MIXTURE) Secondary: 35065-27-1 - 2,2'-4,4',5,5'-Hexachlorobiphenyl (PCB 153) 57465-28-8 - ...
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Polychlorinated biphenyls (PCBs) mixtures (N21405) http://ntpfuture.niehs.nih.gov/go/nm-n21405 Nomination Summary for Polychlorinated biphenyls (PCBs) mixtures (N21405) The Nomination you attempted to access could not be found. Please try your search again.
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3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS (GAVAGE STUDIES) NATIONAL ... CARCINOGENESIS STUDIES OF 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN SPRAGUE-DAWLEY ... of Lesions in Female Rats in the 2-Year Gavage Study of PCB 126 . . . . . . . . 89 APPENDIX B Organ Weights and ... . . . . . . . . . . . . . . . . . . . . . . . . . . . 245 4 PCB 126, NTP TR 520 SUMMARY Background 3,3N4,4N5-Pentachlorobiph...
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SIGNS AND SYMPTOMS: Chloracne and other dermal alterations are well known markers of exposure to PCBs and structurally related halogenated aromatic hydrocarbons. Chloracne and other dermal alterations have been reported in subjects occupationally exposed to PCBs and in individuals exposed by accidental ingestion of rice oil contaminated with high concentrations of PCBs, CDFs, and related chemicals (Yusho and Yu-Cheng). In general, chloracne appears in individuals with serum PCB levels 10-20 ...
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2,2N,4,4N,5,5N-HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS (GAVAGE STUDIES) ... CARCINOGENESIS STUDIES OF 2,2N,4,4N,5,5N-HEXACHLOROBIPHENYL (PCB 153) (CAS NO. 35065-27-1) IN FEMALE HARLAN SPRAGUE-DAWLEY ... Service U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES 2 PCB 153, NTP TR 529 CONTRIBUTORS National Toxicology Program ... of Lesions in Female Rats in the 2-Year Gavage Study of PCB 153 . . . . . . . . 61 APPENDIX B Organ Weights and ...
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2,3´,4,4´,5-PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE HARLAN SPRAGUE-DAWLEY RATS (GAVAGE STUDIES) ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF 2,3´,4,4´,5-PENTACHLOROBIPHENYL (PCB 118) (CAS NO. 31508-00-6) IN FEMALE HARLAN ... APPENDIX A Summary of Lesions in Female Rats in the 2-Year Gavage Study of PCB 118 . . . . . . . . . 91 APPENDIX B Organ ... . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 4 PCB 118, NTP TR 559 SUMMARY Background 2,3´,4,4´,5-Pentachloro...
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Toxic equivalency factor evaluation (PCB 153- 2,2'-4,4',5,5'-hexachlorobiphenyl) M960054 Link to Data Search (Data is not ... Toxic equivalency factor evaluation (PCB 153- 2,2'-4,4',5,5'-hexachlorobiphenyl) - M960054 CASRN: 35065-27-1 Related: 2,2',4,4',5,5'-HEXACHLOROBIPHENYL (PCB 153) Formula: C12-H4-Cl6 Synonyms/Common Names: 1,1'-BIPHENYL, 2,2',4,4',5,5'-HEXACHLORO- (9CI) 2,2',4,4',5,5'-HEXACHLOROBIPHENYL (PCB 153) (TOXIC EQUIVALENCY FACTOR EVALUATION) PCB 153 (TOXIC EQUIVALENCY FACTOR ...
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(CAS NO. 57117-31-4), AND 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN SPRAGUE-DAWLEY ... (CAS NO. 57117-31-4), AND 3,3N,4,4N,5-PENTACHLOROBIPHENYL (PCB 126) (CAS NO. 57465-28-8) IN FEMALE HARLAN SPRAGUE-DAWLEY ... . . . 179 4 A Mixture of TCDD, PeCDF, and PCB 126, NTP TR 526 SUMMARY Background 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF), and 3,3N,4,4N,5- pentachlorobiphenyl (PCB 126) are members of a class of chemicals ...
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...PCB 126) 3,3',4,4',5-pentachlorobiphenyl) M960052 Link to Data Search (Data is not available for all studies.) Chemical Properties Toxicity Effects (HSDB) Overviews of NTP Protocols http://ntp.niehs.nih.gov/go/ts-m960052 Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl) - M960052 CASRN: 57465-28-8 Related: TOXIC EQUIVALENCY FACTOR EVALUATION (PENTACHLOROBIPHENYL) Formula: C12-H5-Cl5 Synonyms/Common Names: 1,1'-BIPHENYL, 3,3',4,4',5-PENTACHLORO- (9CI) PCB 126 PCB 126 ...
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(CASRN 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) http://ntp.niehs.nih.gov/go/9307 ...PCB 126) (CASRN 57465-28-8) Toxicology and Carcinogenesis Studies of a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) (CAS No. 1746-01-6), 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB ... Chemical Formula: TCDD: C12H4Cl4O2 PeCDF: C12H3Cl5O PCB 126: C12H5Cl5 DIOXIN TOXIC EQUIVALENCY FACTOR EVALUATION OVERVIEW ...
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...PCB 126) M950120 Link to Data Search (Data is not available for all studies.) Chemical Properties Toxicity Effects (HSDB) Overviews of NTP Protocols http://ntp.niehs.nih.gov/go/ts-m950120 3,3,4,4,5-Pentachlorobiphenyl (PCB 126) - M950120 CASRN: ... Synonyms/Common Names: 1,1'-BIPHENYL, 3,3',4,4',5-PENTACHLORO- (9CI) PCB 126 Known Uses: Dielectric medium in transformers ... Single Gavage Administration Toxicokinetic Study of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) in Female Harlan Sprague-Dawley ...
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Nomination Summary for Dioxin toxic equivalence factor studies (N95036) Dioxin toxic equivalence factor studies Specific Substances: 2,2'-4,4',5,5'-Hexachlorobiphenyl (PCB 153), 2,3',4,4',5-Pentachlorobiphenyl, 3,3,4,4,5-Pentachlorobiphenyl (PCB 126), 1,2,3,7,8-Pentachlorodibenzo-p-dioxin, 2,3,4,7,8-Pentachlorodibenzofuran, TEF evaluation (Binary mixture; PCB 126/PCB 153), 2,3,7,8-Tetrachlorodibenzo-p-dioxin, TEF evaluation (Dioxin mixture) Nomination Date: 03/27/1995 Nominator: NIEHS, EPA ...
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Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508-00-6) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Chemical (Study Title) CASRN Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory TEF Evaluation (PCB Mixture; PCB 126/PCB 118) TEFPCBMIX 12/09/2004 One of 2 dioxin-like compounds plus mixtures being tested to determine if the TEFs for these ...
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0 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) http://ntp.niehs.nih.gov/go/16325 Abstract for TR-530 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) and ...
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The substance may cause liver damage. High exposure can damage the nervous system. PCBs are readily absorbed into the body by all routes of exposure. They may persist in tissues for years after exposure stops. The symptoms below may be due to PCBs or to chemical contaminants. High levels of PCB vapor, 1-10 mg/cu m, may produce burning feeling ... These effects may last for months. Digestive disturbance has been reported in some individuals. PCBs may impair the function of the immune system. High ...
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1 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508-00-6) http://ntp.niehs.nih.gov/go/16331 Abstract for TR-531 - Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CASRN 31508-00-6) Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) and 2,3',4,4',5-Pentachlorob...
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Target Organs and Levels of Evidence for TR-559 Toxicology and Carcinogenesis Studies of TEF evaluation (PCB 118) (CASRN 31508-00-6) in Harlan Sprague-Dawley Rats (Gavage Studies) Chemical (Study Title) CASRN Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory TEF evaluation (PCB 118) 31508-00-6 02/25/2009 Polychlorinated biphenyls (PCBs) and their mixtures including 2,3',4,4',5-pentachlorobiphenyl (PCB 118) were produced commercially before 1977 for the electric industry as ...
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Toxicology and Carcinogenesis Studies of a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) and 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Chemical (Study Title) CASRN Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory TEF evaluation (Binary mixture; PCB 126/PCB 153) TEFBINARYMIX 12/09/2004 Used in the electric industry as dielectric insulating fluids for transformers and ...
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Toxicology and Carcinogenesis Studies of 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Chemical (Study Title) CASRN Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory Toxic equivalency factor evaluation (PCB 153- 2,2'-4,4',5,5'-hexachlorobiphenyl) 35065-27-1 12/09/2004 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) was produced as a component of some commercial PCB mixtures before 1977 for the electric industry ...
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9 - 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) http://ntp.niehs.nih.gov/go/20264 Abstract for TR-529 - 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) (CASRN 35065-27-1) Toxicology and Carcinogenesis Studies of 2,2',4,4',5,5',-Hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in Female Harlan Sprague-Dawley Rats (Gavage Studies) ... evaluate the chronic toxicity and carcinogenicity of DLCs and structurally related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...
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0 - 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) http://ntp.niehs.nih.gov/go/9301 Abstract for TR-520 - 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Toxicology and Carcinogenesis Studies of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Link to the full study ... and carcinogenicity of DLCs and structurally-related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ***** 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) ...
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Toxicology and Carcinogenesis Studies of 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Chemical (Study Title) CASRN Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl) 57465-28-8 02/17/2004 Dielectric medium in transformers Gavage FEMALE RATS ONLY: PCB-126 -- 0, 10, 30, 100, 175, 300, 550, OR 1000 NG/KG; 100/DOSE Battelle Columbus ...
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9 - 2,3',4,4',5-Pentachlorobiphenyl (PCB 118)(CASRN 31508-00-6) http://ntp.niehs.nih.gov/go/33539 Abstract for TR-559 - 2,3',4,4',5-Pentachlorobiphenyl (PCB 118)(CASRN 31508-00-6) TR-559 Toxicology and Carcinogenesis Studies of 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CAS No. 31508-00-6) in Female Harlan Sprague-Dawley Rats (Gavage Studies) Link ... evaluate the chronic toxicity and carcinogenicity of DLCs and structurally related polychlorinated biphenyls (PCBs) and mixtures of these compounds. ...
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CAS Registry Number: 35065-27-1 Toxicity Effects Selected toxicity information from HSDB, one of the National Library of Medicine's databases. 1 Names (NTP) 1,1'-BIPHENYL, 2,2',4,4',5,5'-HEXACHLORO- (9CI) PCB 153 2,2',4,4',5,5'-HEXACHLOROBIPHENYL (PCB 153) (TOXIC EQUIVALENCY FACTOR EVALUATION) 1,1'-BIPHENYL, 2,2',4,4',5,5'-HEXACHLORO- (9CI) 2,2'-4,4',5,5'-Hexachlorobiphenyl (PCB 153) PCB 153 (TOXIC EQUIVALENCY FACTOR EVALUATION) Toxic equivalency factor evaluation (PCB 153- 2,2'-4,4',5,5'-hexach...
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Vary from mobile oily liquids to white crystalline solids and hard noncrystalline resins. The majority of individual PCBs are waxlike or crystalline solids when isolated in the pure state, a few congeners are liquids at room ... None found log P (octanol-water) ... literature Kow values will vary. These increase with increasing chlorination. log Kow values at 25 deg C: 3.76 (biphenyl); 5.7 (Cl4-PCB's); 6.0 (Cl5-PCB's); 7.0 (Cl6-PCB's); 8.26 (Cl10-PCB's). pH None found Solubilities Solubility ...
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...PCB 126) 57117-31-4 - 2,3,4,7,8-Pentachlorodibenzofuran 57117-31-4 - TEF evaluation (PECDF (Pentachlorodibenzofuran)) 1746-01-6 - TEF evaluation (TCDD) 57465-28-8 - TEF transgenics (PCB 126) 57117-31-4 - TEF transgenics (PECDF) 1746-01-6 - TEF transgenics (TCDD) 1746-01-6 - 2,3,7,8-Tetrachlorodibenzo-p-dioxin 57465-28-8 - Toxic equivalency factor evaluation ((PCB 126) ... (CASRN 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) in Female Harlan Sprague-Dawley Rats ...
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Evaluate strength/weaknesses, consistency, and biological plausibility of findings reported in humans and experimental animals for certain environmental chemicals including arsenic and cadmium, PCBs, DDT/DDE, other organohalogens, bisphenol ... The NTP has developed an Excel database and software program to allow users to visually look across the epidemiology studies for patterns of results for POPs subtypes (e.g., Agent Orange, total PCBs, individual PCB congeners, DDE, PFOS, etc.). The software ...
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Nomination Summary for Polybrominated diphenyl ethers (N20207) Polybrominated diphenyl ethers Specific Substances: No Specific Substances or Agents are Selected for this Nomination Nomination Date: 11/15/2001 Nominator: Learning Disabilities Association of America Rationale: Proper thyroid function is essential for embryonic and fetal development. Additional research on polybrominated diphenyl ethers, which may disrupt development similar to PCBs, may help reduce the incidence of developmental ...
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status, BMI, and other pollutants (p,p'-DDE, HCB, PCBs, mirex, mercury) Binary Logistic Regression predicting ... Blood Pb ≥1.2 µg/dL 12.7 years (12.2-13.1) Increasing PCB levels were associated with a greater likelihood of having ... Wilrijk=50%; Hoboken=33% development stage), heavy metal, PCB, and other levels in urine or blood, cystatin C and other ... pubic- hair stage), height, weight, phytoestrogen, BPA, DDE, PCB exposure Modified Poisson regression models Adjustments ...
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consumed rice oil contaminated with /polychlorinated biphenyls/ (PCBs) heat exchange fluid in Japan in 1968 (Yusho incident) and Taiwan in 1979 (Yu-Cheng incident). The PCBs were heated in thermal heat exchangers before contamination ... The concentrations of PCBs and PCQs in the rice oils were l00- to 500-fold greater than the CDFs. Because there are no data on human health effects of CDFs alone and little is known about the interactive effects of CDFs and PCBs and other components of the ...
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Toxicology and Carcinogenesis Studies of a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) (CASRN 1746-01-6), 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CASRN 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) in ... Used as dielectric insulating fluids in transformers & capacitors and used in hydraulic fluids, plastics, & paints. Gavage FEMALE RATS ONLY: 0, (TCDD) 3.3, 7.3, 15.2, OR 33 NG/KG; (PeCDF) 6.6, 14.5, 30.4, OR 66 NG/KG; (PCB 126) 33.3, 73.3, 153, OR ...
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Bioassay of Aroclor® for Possible Carcinogenicity (CASRN 27323-18-8) Chemical (Study Title) CASRN Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory Aroclor 1254 11097-69-1 11/28/1977 Aroclor® is the registered trademark of the Monsanto Chemical Company for their polychlorinated biphenyls (PCBs). PCBs were developed in 1929 primarily for use as heat transfer fluids and dielectrics (insulators). [Pesticide] Dosed-Feed 0,25,50,100 PPM/24 PER GROUP SRI International Levels of ...
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(CASRN 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465-28-8) http://ntp.niehs.nih.gov/go/9307 ...PCB 126) (CASRN 57465-28-8) Toxicology and Carcinogenesis Studies of a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) (CAS No. 1746-01-6), 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB ... Chemical Formula: TCDD: C12H4Cl4O2 PeCDF: C12H3Cl5O PCB 126: C12H5Cl5 DIOXIN TOXIC EQUIVALENCY FACTOR EVALUATION OVERVIEW ...
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mode of action of TCDD and other chlorinated dibenzodioxins, dibenzofurans, and planar polychlorinated biphenyls (PCBs). ... by incineration of municipal, toxic, and hospital wastes, in PCB-filled electrical transformer fires, in smelters, and during ... Fires involving capacitors or transformers containing chlorobenzene and PCBs are potential sources of CDDs. TCDD has been ... Levels of dioxins, dibenzofurans, PCB and DDE congeners in pooled food samples collected in 1995 at supermarkets across the ...
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CAS Registry Number: 57465-28-8 Toxicity Effects Selected toxicity information from HSDB, one of the National Library of Medicine's databases. 1 Names (NTP) PCB 126 PCB 126 (TEF TRANSGENICS) PCB 126 (TOXIC EQUIVALENCY FACTOR EVALUATION) 3,3',4,4',5-PENTACHLOROBIPHENYL (TOXIC EQUIVALENCY FACTOR EVALUATION) TEF TRANSGENICS (3,3',4,4',5 PENTACHLOROBIPHENYL) 1,1'-BIPHENYL, 3,3',4,4',5-PENTACHLORO- (9CI) PCB 126 1,1'-BIPHENYL, 3,3',4,4',5-PENTACHLORO- (9CI) 3,3,4,4,5-Pentachlorobiphenyl (PCB 126) TEF ...
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... QUICKI 1/[log(FG)+log (fasting insulin)]) PCDDs, PCDFs, PCBs (serum, pg-TEQ/g- lipid) adjusted Pearson correlations (r) ... r=-0.21, ns 1,2,3,6,7,8-HxCDF; r=-0.17, ns PCBs 1,2,3,4,6,7,8-HpCDD; r=-0.38, p=0.07 2,3,4,6,7,8-HxCDF; ... TEQ: r=-0.18, ns 2,3,3',4,4'-PeCB 105; r=-0.42, p=0.06 PCBs TEQ: r=-0.42, p=0.02 Total TEQ; r=-0.32, p=0.06 ... diabetes (FG value >125 mg/mL, use of diabetes medication) PCB, PCB153, PCB74, DDE, mirex, HCB (serum, lipid adjusted ng/g ...
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Link to Data Search (Data is not available for all studies.) Chemical Properties Toxicity Effects (HSDB) Overviews of NTP Protocols http://ntpfuture.niehs.nih.gov/go/ts-10444-d Biphenyl - 10444-D CASRN: 92-52-4 Formula: C12-H10 Synonyms/Common Names: 1,1'-BIPHENYL (9CI) Known Uses: Intermediate For PCB's, fungistat in packaging citrus fruit, dye asst. For polyesters occurs in coal tar. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco ...
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CAS Registry Number: 31508-00-6 Toxicity Effects Selected toxicity information from HSDB, one of the National Library of Medicine's databases. 1 Names (NTP) 1,1'-BIPHENYL,2,3',4,4',5-PENTACHLORO- (9CI) PCB-118 (TOXIC EQUIVALENCY FACTOR EVALUATION) TOXIC EQUIVALENCY FACTOR EVALUATION (2,3',4,4',5-PENTACHLOROBIPHENYL) PCB 118 TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 118) 2,3',4,4',5-Pentachlorobiphenyl TEF evaluation (PCB 118) No toxicity information found at HSDB, one of the National Library of ...
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