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TOX-81: α-Pinene (CASRN 80-56-8) Administered by Inhalation... 2.8MB
https://ntp.niehs.nih.gov/go/tox081
... following an intentional ingestion of pine oil (57% α-pinene, 8% β-pinene, 26% ∆ 3 ... Two epidemiological studies have examined turpentine or terpene exposure in occupational ...
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TOX-1: Hexachloro-1,3-butadiene(CASRN 87-68-3) 415KB
https://ntp.niehs.nih.gov/go/tox001
... Hexachloro-1,3-butadiene is a colorless liquid with a faint, turpentine-like odor. ... per sex) were given 0, 0.4, 1, 2.5, 6.3, or 15.6 mg/kg per day by gavage in arachid oil. ...
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TOX-59: Chloral Hydrate (CASRN 302-17-0) 10.8MB
https://ntp.niehs.nih.gov/go/tox059
... soluble in turpentine, petroleum ether, carbon tetrachloride, benzene, and toluene. ... in animals treated with chloral hydrate followed by croton oil (Roe and Salaman, 1955). ...
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TOX-86: Toxicity Studies of Cedarwood Oil (Virginia) (CASRN 8000... 5.9MB
https://ntp.niehs.nih.gov/go/tox086
oil (ViRgiNia) (caSRN 8000-27-9) admiNiSTeRed deRmally To f344/N RaTS aNd B6c3f1/N mice NTP TOX 86 NOVEMBER 2016 NTP Technical Report on the Toxicity Studies of Cedarwood Oil ...
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TOX-12: Castor Oil (CASRN 8001-79-4) 367KB
https://ntp.niehs.nih.gov/go/tox012
N T P T E C H N I C A L R E P O R T O N T H E TOXICI TY STUDIES OF CASTOR OIL IN F344/N ... (919-541-3991). TOXICITY STUDIES of CASTOR OIL (CAS No.: 8001-79-4) IN F344/N RATS AND ...
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Abstract for TOX-81 59KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox081
Abstract α-Pinene is the main component in turpentine and is used as a fragrance and ... limit for α-pinene is 100 ppm (as turpentine) and the threshold limit value is 20 ...
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Abstract for TOX-86 67KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox086
Toxicity Studies of Cedarwood Oil (Virginia) Administered Dermally to F344/N Rats and B6C3F1/N Mice CASRN: 8000-27-9 Synonyms/Common Names: Cedar oil; cedarwood oil; oil of ...
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Abstract for TOX-12 52KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox012
Castor Oil in F344/N Rats and B6C3F1 Mice (Dosed Feed Studies) CASRN: 8001-79-4 Chemical Formula: C57H104O9 Molecular Weight: 933.4396 Synonyms/Common Names: Ricinus oil; oil of ...
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TOX-14: p-Chloro-a,a,a-Trifluorotoluene (CASRN 98-56-6) 2.2MB
https://ntp.niehs.nih.gov/go/tox014
(CAS NO: 98-56-6) Administered in Corn Oil and α α α α-Cyclodextrin to F344/N Rats ... (CAS NO: 98-56-6) Administered in Corn Oil and α α α α-Cyclodextrin to F344/N Rats ...
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Abstract for TOX-17 54KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox017
Toxicity studies were conducted by applying black newsprint inks or mineral oils to ... An industrial grade mineral oil, used as an extender for newsprint ink formulation, and ...
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Abstract for TOX-56 59KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox056
toxicity of carisoprodol administered in corn oil and in 0.5% methylcellulose by gavage. ... per kilogram body weight in corn oil by gavage or 0, 100, 200, 400, or 800 mg/kg ...
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Abstract for TOX-76 56KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox076
as a corrosion inhibitor for steel in oil field operations. 2,4-Decadienal was ... received 2,4-decadienal (at least 93% pure) in corn oil by gavage for 2 weeks or 3 months. ...
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Abstract for TOX-95 67KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox095
It is a major constituent in essential oil extracted from either the seed, which is the ... myristicin (greater than 94% pure) in corn oil by gavage at doses of 0, 10, 30, 100, 300, ...
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TOX-56: Toxicity Studies of Carisoprodol (CASRN 78-44-4) Administered... 2.1MB
https://ntp.niehs.nih.gov/go/tox056
... Microbiological Associates, Inc. Conducted studies of carisoprodol in corn oil and ... . . . . . . . . . 33 Carisoprodol in Corn Oil . . . . . . . . . . . . . . . . . . . . . . ...
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Abstract for TOX-14 55KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox014
Toxicity Studies of p-Chloro-alpha,alpha,alpha-Trifluorotoluene Administered in Corn Oil ... day for 14 consecutive days in either corn oil or in an experimental molecular complex ...
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Abstract for TOX-82 58KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox082
agent against acid-tolerant food microflora; and to produce synthetic anise oil. ... mice were given estragole (greater than 99% pure) in corn oil by gavage for 3 months. ...
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TOX-17: Black Newsprint Inks 2.1MB
https://ntp.niehs.nih.gov/go/tox017
... of Black Newsprint Inks and Mineral Oils ......of Black Newsprint Inks and Mineral Oils ......
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TOX-95: Toxicity Studies of Myristicin (CASRN 607-91-0) Administered... 3.8MB
https://ntp.niehs.nih.gov/go/tox095
.........8 Corn Oil ......It is a major constituent in essential oil extracted from either the seed, which is the ...
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TOX-85: Toxicity Study of Tetrabromobisphenol A-bis(2,3-dibromopropyl... 2.7MB
https://ntp.niehs.nih.gov/go/tox085
.........5 Corn Oil ......-bis(2,3-dibromopropyl ether) (approximately 94% pure) in corn oil by gavage for 3 months. ...
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Abstract for TOX-09 58KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox009
Cresols are monomethyl derivatives of phenol, and are found as constituents of coal tar, in various industrial solvents and resins, and in some essential oils. In 28-day toxicity ...
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TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.0MB
https://ntp.niehs.nih.gov/go/tox099
.........8 Corn Oil ....../N mice were administered a GGE formulation in corn oil by gavage for 28 days or 3 months. ...
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TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox99_508.pdf
.........8 Corn Oil ....../N mice were administered a GGE formulation in corn oil by gavage for 28 days or 3 months. ...
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TOX-4: 1,2-Dichloroethane (Ethylene Dichloride) (CASRN 107-06... 4.0MB
https://ntp.niehs.nih.gov/go/tox004
... 150®; Brocide®; Dutch liquid; Dutch oil ABSTRACT Thirteen-week studies were ... admin- istered 1,2-dichloroethane in corn oil by gavage to compare toxicity resulting ...
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TOX-76: Toxicity Studies of 2,4-Decadienal (CASRN 25152-84-5... 2.5MB
https://ntp.niehs.nih.gov/go/tox076
... as a corrosion inhibitor for steel in oil field operations. 2,4-Decadienal was ... F344/N rats and B6C3F1 mice received 2,4-decadienal (at least 93% pure) in corn oil by ...
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Abstract for TOX-40 57KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox040
Doses of 0, 37, 75, 150, 300, or 600 mg/kg were administered in a corn oil vehicle. The ... mice, following 4 weeks of exposure to beta-bromo-beta-nitrostyrene by corn oil gavage. ...
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Abstract for TOX-04 55KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox004
In addition, groups of 10 F344/N rats of each sex were administered 1,2-dichloroethane in corn oil by gavage to compare toxicity resulting from bolus administration with that of ...
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Abstract for TOX-99 61KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox099
.../N mice were administered a GGE formulation in corn oil by gavage for 28 days or 3 months. ... mg GGE formulation/kg body weight/day in corn oil by gavage, 5 days per week for 3 months. ...
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TOX-15: t-Butyl Perbenzoate (CASRN 614-45-9) 1.1MB
https://ntp.niehs.nih.gov/go/tox015
... that t- BP, adminstered by gavage in corn oil in doses ranging from 70 to 1112 mg/kg, ... Subcommittee Paul T. Bailey, PhD Mobil Oil Corporation Toxicology Division Princeton, ...
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TOX-28: Tetrachlorophthalic Anhydride (CASRN 117-08-8) 1.1MB
https://ntp.niehs.nih.gov/go/tox028
... 10 mice of each sex received TCPA in corn oil vehicle by oral gavage (5 days/week) at ... In summary, clear evidence of organ toxicity following administration of TCPA in corn oil ...
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TOX-40: b-Bromo-b-Nitrostyrene (CASRN 7166-19-0) 2.6MB
https://ntp.niehs.nih.gov/go/tox040
... Doses of 0, 37, 75, 150, 300, 1 or 600 mg/kg were administered in a corn oil vehicle. The ... female mice, following 4 weeks of exposure to -bromo- -nitrostyrene by corn oil gavage. ...
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TOX-65: 3,3',4,4'-Tetrachloroazobenzene 2.7MB
https://ntp.niehs.nih.gov/go/tox065
... 3,3N,4,4N-tetrachloroazobenzene in corn oil by gavage 5 days a week at doses of 0, ... in corn oil by gavage 5 days a week at doses of 0, 1, 3.2, 10, 32, or 100 mg/kg. ...
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TOX-82: 3-Month Toxicity Studies of Estragole (CASRN 140-67-0... 1.9MB
https://ntp.niehs.nih.gov/go/tox082
... agent against acid-tolerant food microflora; and to produce synthetic anise oil. ... mice were given estragole (greater than 99% pure) in corn oil by gavage for 3 months. ...
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TOX-99: Lay Summary; Gum Guggul Extract 223KB
https://ntp.niehs.nih.gov/sites/default/files/2025-04/tox099_summary_508.pdf
.../day in corn oil for 5 days per week over 3 months. Groups of 15 male and 15 female mice were orally administered 15.5, 31, 62.5, 125, or 250 mg/kg/day in corn oil for 5 days per ...
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TOX-8: D&C Yellow No. 11 (CASRN 8003-22-3) 2.1MB
https://ntp.niehs.nih.gov/go/tox008
... Solvent Yellow 33; Nitro Fast Yellow SL; Oil Yellow SIS; Petrol Yellow C; Quinolin ... Solvent Yellow 33; Nitro Fast Yellow SL; Oil Yellow SIS; Petrol Yellow C; Quinoline ...
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TOX-33: 2-Chloronitrobenzene (CASRN 88-73-3) and 4-Chloronitrobenzene... 10.2MB
https://ntp.niehs.nih.gov/go/tox033
... Bailey, Ph D Environmental and Health Sciences Laboratory Mobil Oil Corporatio n Princeton ... nitrobenzene, ridtrophenol, aniline, and oil additives (Shafer et aL, 1979) . 9 0 0 0 0 ...
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TOX-45: Renal Selected Halogenated Ethanes 1.2MB
https://ntp.niehs.nih.gov/go/tox045
... All chemicals were administered by gavage in corn oil to groups of five male rats once ... Groups of female rats used as controls received either pentachloroethane in corn oil or ...
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TOX-66: 3,3',4,4'-Tetrachloroazoxybenzene 3.9MB
https://ntp.niehs.nih.gov/go/tox066
... 3,3N,4,4N-tetrachloroazoxybenzene in corn oil by gavage at doses of 0, 12.5, 32, 80, 200, ... female mice received 0, 1, 3.2, 10, 32, or 100 mg/kg in corn oil by gavage, 5 days a week. ...
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TOX-77: Lay Summary; Hexachlorobenzene (CASRN 118-74-1) 191KB
https://ntp.niehs.nih.gov/sites/default/files/2025-03/tox077_summary_508.pdf
.../kilogram (kg) body weight/day in a mixture of corn oil and acetone for 3 months. Control animals were given the corn oil and acetone mixture with no HCB added (0 mg/kg/day HCB). ...
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Abstract for TOX-65 57KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox065
3,3',4,4'-Tetrachloroazobenzene in corn oil by gavage 5 days a week at doses of 0, ... in corn oil by gavage 5 days a week at doses of 0, 1, 3.2, 10, 32, or 100 mg/kg. ...
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Abstract for TOX-66 57KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox066
3,3',4,4'-tetrachloroazoxybenzene in corn oil by gavage at doses of 0, 12.5, 32, 80, 200, ... female mice received 0, 1, 3.2, 10, 32, or 100 mg/kg in corn oil by gavage, 5 days a week. ...
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Abstract for TOX-77 61KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox077
(mg/kg/day) in corn oil:acetone (99:1) by gavage, 5 days/week for 13 weeks (3 months). ... core study and 10 elimination study) were administered the corn oil:acetone vehicle only. ...
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Abstract for TOX-85 60KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox085
...-bis(2,3-dibromopropyl ether) (approximately 94% pure) in corn oil by gavage for 3 months. ... ether)/kg body weight in corn oil by gavage, 5 days per week for 14 weeks, ...
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TOX-7: 1,2,4,5-Tetrachlorobenzene (CASRN 95-94-3) 4.1MB
https://ntp.niehs.nih.gov/go/tox007
... He said that the ratio of corn oil to diet should be stated (see Table 2, page 14). The ...2,4,5-tetrachloroben- zene (w/w) with corn oil until dissolved (final corn oil ...
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TOX-55: Toxicity Studies of trans-1,2-Dichloroethylene (CASRN... 1.7MB
https://ntp.niehs.nih.gov/go/tox055
... and as an extractant for rubber and for oil and fat from fish. cis,trans-1,2-Dichloroet... 1,2-dichloroethylene in corn oil by gavage at 400 or 1,500 mg/kg (Jenkins et al., 1972). ...
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Abstract for TOX-28 54KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox028
Groups of 10 rats and 10 mice of each sex received TCPA in corn oil vehicle by oral gavage ... In summary, clear evidence of organ toxicity following administration of TCPA in corn oil ...
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TOX-9: Cresols (CASRNs 95-48-7, 108-39-4, 106-44-5) 6.1MB
https://ntp.niehs.nih.gov/go/tox009
... of coal tar, in various industrial solvents and resins, and in some essential oils. ... ointments, pastes, lotions, bath and body oils, shampoos, soaps, and gels (IARC, 1985). ...
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TOX-43: o-,m-, and p-Chloroanilines (CASRNs 95-51-2; 108-42-9... 5.0MB
https://ntp.niehs.nih.gov/go/tox043
... after the intragastric administration in oil of 150 mg m-chloroaniline per kilogram body ... injections of o- or m-chloroaniline dissolved in corn oil at 24-hour intervals. ...
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TOX-47: Toxicity Studies of Methacrylonitrile (CASRN 126-98-7... 1.2MB
https://ntp.niehs.nih.gov/go/tox047
... of 100 mg/kg methacrylonitrile in corn oil, 43% of the dose was eliminated in the ... of methacrylonitrile in corn oil rather than in water resulted in slower ...
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TOX-61: Toxicity Studies of Benzophenone (CASRN 119-61-9) Administered... 1.2MB
https://ntp.niehs.nih.gov/go/tox061
... that benzophenone is a component of emissions from a standard residential oil burner. ... with benzophenone dissolved in corn oil; the total dosing volume was 0.4 mL. ...
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Abstract for TOX-45 54KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox045
All chemicals were administered by gavage in corn oil to groups of five male rats once daily for 21 days. The doses selected for study, 0.62 and 1.24 mmol/kg per day, were based on ...