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TR-418: p-Nitroaniline (CASRN 100-01-6) in B6C3F1Mice (Gavage... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr418.pdf
... . . . . . . . ... . . 203 CAS No. 100-01-6 Chemical Formula: C,H,N,O, p-Nitroaniline is an intermediate in the preparation of several azo dyes used for coloring consumer products. ...
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Abstract for TR-418 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr418
Abstract for TR-418 Toxicology and Carcinogenesis Studies of p-Nitroaniline in B6C3F1 Mice (Gavage Studies) CASRN: 100-01-6 Chemical Formula: C6H6N2O2 Molecular Weight: 138.12 ...
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Target Organs and Levels of Evidence for TR-418 57KB
https://ntp.niehs.nih.gov/data/tr/400s/tr418levels
Target Organs and Levels of Evidence for TR-418 Toxicology and Carcinogenesis Studies of p-Nitroaniline (CASRN 100-01-6) in B6C3F1 Mice (Gavage Studies) Chemical (Study Title) ...
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Minutes: BSC TR; Nov. 21, 1991 728KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1991/minutesbsctrrs19911121_508.pdf
Hart, 919/541-3971; FTS 629-3971. CONTENTS Technical Report CAS NO. Long-Term Studies 1,3 Butadiene 106-99-0 Inhalation p-Nitroaniline 100-01-6 Gavage o-Nitroanisole 91-23-6 Feed ...
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TR-484: 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr484.pdf
... He compared the results for this study with those from the NTP bioassay of p-nitroaniline ... Medinsky asked for staff comment on the p-nitroaniline study. Dr. Roycroft responded that ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Evidence NE No Evidence NE No Evidence NE No Evidence TR-418 11/21/91 p-Nitroaniline 100-01-6 NT Chemical Not Tested in Species/Sex NT Chemical Not Tested in Species/Sex EE ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Report TR-418 PDF (10.35 MB) Toxicology and Carcinogenesis Studies of p-Nitroaniline (CASRN 100-01-6) in B6C3F1 Mice (Gavage Studies) 1993 Technical Report TR-417 PDF (7.44 MB) ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Report TR-418 PDF (10.35 MB) Toxicology and Carcinogenesis Studies of p-Nitroaniline (CASRN 100-01-6) in B6C3F1 Mice (Gavage Studies) 1993 Technical Report TR-417 PDF (7.44 MB) ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-418 PDF (10.35 MB) Toxicology and Carcinogenesis Studies of p-Nitroaniline (CASRN 100-01-6) in B6C3F1 Mice (Gavage Studies) 1993 Long-Term Carcinogenicity TR-417 PDF ...
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TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf
... 3/50 y-Butyrolactone 1/48 1/48 2/48 p-Nitroaniline 1/50 0150 1/50 Pentachloroanisole 0/... Furfural 5/50 y-Butyrolactone 4/50 p-Nitroaniline 4/50 Pentachloroanisole 4/50 Total ...
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RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
... 99-09-2 138.12 4-Nitroaniline 100-01-6 138.12 Nitrobenzene 98-95-3 123.11 ... 3-Nitroaniline 99-09-2 4-Nitroaniline 100-01-6 Nitrobenzene 98-95-3 Nitromethane ...
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RoC Background Document for Nitrobenzene; Sept. 19, 2002 1.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/nbpub_no_appendices_508.pdf
... 100-02-7 Male mice d - No Evidence Female mice d - No Evidence TR-418 p-Nitroaniline b 100-01-6 NH Male mice - Equivocal Evidence; liver tumors Female mice - No Evidence ...
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TR-503: Chloral Hydrate (Ad Libitum and Dietary Controlled) ... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr503.pdf
... Gavage 416 o-Nitroanisole Feed 418 p-Nitroaniline Gavage 420 Triamterene Feed 421 Talc ... 408 Mercuric Chloride Gavage 418 p-Nitroaniline Gavage 425 Promethazine Hydrochloride ...
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TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 10.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr509.pdf
... Diet at Southern Research Institute b p-Nitroaniline 3/50 1/50 4/50 Salicylazosulfapyridin... Diet at Southern Research Institute b p-Nitroaniline 0/50 0/50 0/50 Salicylazosulfapyridin...
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Japanese Minimum Requirements for Biological Products 2.0MB
https://ntp.niehs.nih.gov/iccvam/methods/biologics/vaccine/japan-minreqs.pdf
... color developed by the reaction with the p-nitroaniline and nitrous acid test solution. ... solution and then 1mL of p-nitroaniline-sodium nitrite test solution and shake well. ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... Technical Report 189. https://ntp.niehs.nih.gov/go/tr189abs National Toxicology Program (NTP). Testing status of p-Nitroaniline 10217-F, CASRN 100-01-6. Research Triangle Park, NC: ...
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Public Comment: 2-Butoxyethanol (Attachment); Seth Barna; RoC... 758KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/barna_attachmentacc_508be.pdf
... Three compounds (2-butoxyethanol, p-nitroaniline, and para-chloroaniline) were associated with a relatively high incidence of Kupffer cell pigmentation consisting of hemosiderin in ...
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TOX-33: 2-Chloronitrobenzene (CASRN 88-73-3) and 4-Chloronitrobenzene... 10.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox33.pdf
... R ., LEVINSKAS, G . J ., AND TERRILL, J . B . (1986b) . Subchronic inhalation toxicity of p-nitroaniline and p-nitrochlorobenzene in rats . Fundam. Appl. Toxicol. 7, 618-627 . ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
... Acid Ethylene Glycol Pentachloroanisole Polysorbate 80 o-Nitroanisole p-Nitrophenol p-Nitroaniline HC Yellow 4 Triamterene Talc Coumarin Dihydrocoumarin o-Benzyl-p-chlorophenol ...
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TR-473: Theophylline (CASRN 58-55-9) in F344/N Rats and B6C3F1Mice... 11.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr473.pdf
... 7/50 26/50 Furfural 9/50 7/50 16/50 p-Nitroaniline 19/50 10/50 25/50 Pentachloroanisole .../50 2/50 7/50 Furfural 1/50 4/50 5/50 p-Nitroaniline 13/50 7/50 17/50 Pentachloroanisole ...
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TR-441 Comparative Initiation/Promotion Skin Paint Studies of... 11.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr441.pdf
... TLC was performed on Silica Gel 60 F-254plates using two solvent systems: 1) to1uene:acetone (9:1), and 2) to1uene:ethyl acetate (l:l), with p-nitroaniline as a reference standard. ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
... 306 248 491 314 352 439 313 462 396 266 368 410 500 451 454 Nickel Subsulfide 453 p-Nitroaniline 418 o-Nitroanisole 416 p-Nitrobenzoic Acid 442 Nitrofurantoin 341 Nitrofurazone ...
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TR-319: 1,4-Dichlorobenzene (CASRN 106-46-7) in F344/N Rats and... 17.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr319.pdf
... The procedure is based on the method of Szasz (1969) in which GGTP catalyzes the conversion of gamma-glutamyl-p-nitroanilide to p-nitroaniline, which absorbs at 405 nm. Enzyme ...
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TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf
... Alcohol 416 o-Nitroanisole 370 Benzofuran 417 p-Nitrophenol 371 Toluene 418 p-Nitroaniline 372 3,3-Dimethoxybenzidine Dihydrochloride 419 HC Hellow 4 373 Succinic Anhydride ...
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TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf
... Naphthalene (Rats) Nickel (II) Oxide Nickel Sulfate Hexahydrate Nickel Subsulfide p-Nitroaniline o-Nitroanisole p-Nitrobenzoic Acid 413 484 326 388 223 208 496 402 382 482 356 492 ...
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TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 13.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr471.pdf
... Also, two earlier studies (1984-1985; mouse life-span and p-nitroaniline studies) and one later study (1993; methyleugenol) were selected. The mouse life-span study was designed to ...
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TR-464: Technical Grade Sodium Xylene Sulfonate (CASRN 1300-72... 9.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr464.pdf
... Also, two earlier studies (1984- 1985; mouse life-span and p-nitroaniline studies) and one later study (1993; methyleugenol) were selected. The mouse life-span study was designed ...
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TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf
... Naphthalene (Rats) Nickel (II) Oxide Nickel Sulfate Hexahydrate Nickel Subsulfide p-Nitroaniline o-Nitroanisole p-Nitrobenzoic Acid Nitrofurantoin Nitrofurazone Nitromethane ...
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TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 9.0MB
https://ntp.niehs.nih.gov/sites/default/files/2023-08/tr471_508.pdf
... Also, two earlier studies (1984-1985; mouse life-span and p-nitroaniline studies) and one later study (1993; methyleugenol) were selected. The mouse life-span study was designed to ...
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TR-426: Corn Oil, Safflower Oil, and Tricaprylin (CASRNs. 8001... 18.8MB
https://ntp.niehs.nih.gov/go/tr426
... 366 Hydroquinone 416 o-Nitroanisole 367 Phenylbutazone 417 p-Nitrophenol . 23 Acid p-Nitroaniline Nalidixic 418 369 Alpha-Methylbenzyl Alcohol 419 HC Yellow 4 370 Benzofuran 420 ...
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TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and B6C3F1Mice... 10.1MB
https://ntp.niehs.nih.gov/go/tr449
... Also, two earlier studies (1984-1985; mouse life-span and p-nitroaniline studies) and one later study (1993; methyleugenol) were selected. The mouse life-span study was designed to ...
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TR-398: Polybrominated Biphenyls (CASRN 67774-32-7)(Firemaster... 14.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr398.pdf
...,3-Dimethoxybenzidine Dihydrochioride 417 p-Nitrophenol 373 Sueeinie Anhydride 418 p-Nitroaniline 374 Glyeidol 419 HC Hellow 4 375 Vinyl Toluene 434 1,3-Butadiene These NTP ...
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TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf
... o-Nitroanisole 369 Alpha-Methylbenzyl Alcohol 417 p-Nitrophenol 370 Benzofuran 418 p-Nitroaniline 371 Toluene 419 HC Hellow 4 372 3,3-Dimethaxybenzidine Dihydrochloride 421 Talc ...
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TR-420: Triamterene (CASRN 396-01-0) in F344/N Rats and B6C3F1Mice... 20.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr420.pdf
... 414 Pentachloroanisole 415 Polysorbate 80 416 o-Nitroanisole 417 p-Nitrophenol 418 p-Nitroaniline 419 HC Hellaw 4 421 Talc 422 Coumarin 423 Dihydmumarin 427 Turmeric Oleoresin 431 ...
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TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf
... 414 Pentachloroanisole 415 Polysorbate $0 416 o-Nitroanisole 417 p-Nitrophenol 418 p-Nitroaniline 419 HC Hellm 4 427 Turmeric Oleoresin 434 1,3-Butadiene 443 Oxazepam These NTP ...
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TR-424: o-Benzyl-p-Chlorophenol (CASRN 120-32-1) in F344/N Rats... 15.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr424.pdf
... o-Nitroanisole 369 Alpha-Methylknzyl Alcohol 417 p-Nitrophenol 370 Benzofuran 418 p-Nitroaniline 371 Toluene 419 HC Hellow 4 372 3.3-Dimethoxyknzidine Dihydrochloride 420 ...
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TR-427: Turmeric Oleoresin (CASRN 8024-37-1) (Major Component... 16.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr427.pdf
... 3,3-Dimetha#ykozidine Dihydrochloride 417 p-Nitrophenol 373 Succinic Anhydride 418 p-Nitroaniline 374 Glycidol 419 HC Hellow 4 375 Vinyl Toluene 434 1,3-Butadiene These PdTp ...
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TR-429: Diethylphthalate (CASRN 84-66-2) in F344/N Rats and B6C3F1Mice... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr429.pdf
... 416 o-Nitroanisole Pentaerythritol Tetranitrate 417 p-Nitrophenol Hydroquinone 418 p-Nitroaniline Phenylbutazone 419 HC Yellow 4 Nalidixic Acid 420 Triamterene a-Methylbenzyl ...
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TR-430: C.I. Direct Blue 218 (CASRN 28407-37-6) in F344/N Rats... 16.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr430.pdf
... Ethylene Glycol Pentachloroanisole Polysorbate 80 o-Nitroanisole p-Nitrophenol p-Nitroaniline HC Hellow 4 Triamterene Talc Coumarin Dihydmumarin o-Benzylp-chlorophenol ...
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TR-431: Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1Mice... 15.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr431.pdf
... 371 Toluene 417 p-Nitrophenol 372 3,3-Dimethoxybenzidine Dihydrochlol ide 418 p-Nitroaniline 373 Succinic Anhydride 419 HC Hellow 4 374 Glycidol 427 Turmeric Oleoresin 375 ...
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TR-432: Barium Chloride Dihydrate (CASRN 10326-27-9) in F344... 15.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr432.pdf
... o-Nitroanisole 369 Alpha-Methylbenzyl Alcohol 417 p-Nitrophenol 370 Benzofuran 418 p-Nitroaniline 371 Toluene 419 HC Hellow 4 372 3,3-Dimethoxybenzidine Dihydrochloride 420 ...
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TR-435: 4,4'-Thiobis(6-t-butyl-m-cresol) (CASRN 96-69-5) in F344... 16.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr435.pdf
... 414 Pentachloroanisole 415 Polysorbate 80 416 o-Nitroanisole 417 p-Nitrophenol 418 p-Nitroaniline 419 HC Yellow 4 420 Triamterene 421 Talc 422 Coumarin 423 Dihydrocoumarin 424 ...
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TR-436: t-Butyl Alcohol (CASRN 75-65-0) in F344/N Rats and B6C3F1Mice... 16.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr436.pdf
... Ethylene Glycol Pentachloroanisole Polysorbate 80 o-Nitroanisole p-Nitrophenol p-Nitroaniline HC Yellow 4 Triamterene Talc Coumarin Dihydrocoumarin o-Benzyl-p-chlorophenol ...
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TR-437: Hexachlorocyclopentadiene (CASRN 77-47-4) in F344/N Rats... 15.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr437.pdf
... 414 Pentachloroanis,le 415 Polysorbate 80 416 o-Nitroanisole 417 p-Nitrophenol 418 p-Nitroaniline 419 HC Yellow 4 420 Triamterene 421 Talc 422 Coumarin 423 Dihydrocoumarin 424 ...
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TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf
... 414 Pentachloroanisole 415 Polysorbate 80 416 o-Nitroanisole 411 p-Nitrophenol 418 p-Nitroaniline 419 HCYellow 4 420 Triamterene 421 Talc 422 coumarin 423 Dihydrocoumarin 424 ...
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TR-440: Ozone (CASRN 10028-15-6) and Ozone/NNK (CASRN 10028-15... 16.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr440.pdf
... Pentachloroanisole 415 Polysorbate 80 416 o-Nitroanisole 417 p-Nitrophenol 418 p-Nitroaniline 419 HC Yellow 4 420 Triamterene 421 Talc 422 Coumarin 423 Dihydrocoumarin 424 ...
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TR-442: p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr442.pdf
... Acid Ethylene Glycol Pentachloroanisole Polysorbate 80 o-Nitroanisole p-Nitrophenol p-Nitroaniline HC Yellow 4 Triamterene Talc Coumarin Dihydrocoumarin o-Benzyl-p-chlorophenol ...
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TR-443: Oxazepam (CASRN 604-75-1) in Swiss-Webster and B6C3F1Mice... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr443.pdf
...,3-Dimethaxybenzidine Dihydrochloride 417 p-Nitrophenol 373 Succinic Anhydride 418 p-Nitroaniline 374 Glycidol 419 HC Hellow 4 375 Vinyl Toluene 434 1,3-Butadiene These N T P ...
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TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr498.pdf
... Naphthalene (Rats) Nickel (II) Oxide Nickel Sulfate Hexahydrate Nickel Subsulfide p-Nitroaniline o-Nitroanisole p-Nitrobenzoic Acid Nitrofurantoin 484 326 388 223 208 496 402 382 ...
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TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1Mice... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr508.pdf
... Naphthalene (Rats) Nickel (II) Oxide Nickel Sulfate Hexahydrate Nickel Subsulfide p-Nitroaniline o-Nitroanisole 466 413 484 326 388 223 208 496 402 382 482 356 492 252 490 374 229 ...