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Search suggestions for "100-41-4".

  1. CEBS Data Related to Ethylbenzene (100-41-4) https://cebs.niehs.nih.gov/cebs/test_article/100-41-4


176 results found for "100-41-4".

  1. TR-466: Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr466.pdf

    ETHYLBENZENE (CAS NO. 100-41-4) IN F344/N RATS AND B6C3F MICE 1 (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 January 1999 NTP TR ...

  2. TOX-10: Ethylbenzene (CASRN 100-41-4) 3.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox010.pdf

    THE TOXICiTY STUDIES OF ETHYLBENZENE IN F344/ N RATS AND B6C3Fi MICE (INHALATION STUDIES) ... TOXICITY STUDIES of ETHYLBENZENE (CAS No. 100-41-4) IN F344/N RATS AND B6C3F1 MICE ...

  3. Public Comment: Ethylbenzene; Jack Snyder; RoC; Jan. 19, 2012 288KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2012/publiccomm/snyder20120228.pdf

    Comments on Nomination of Ethylbenzene for Review for the Report on Carcinogens Dear Dr. ... No.12, 2728 (January 1 9, 2012) SIRC recently has assumed oversight for ethylbenzene ...

  4. Abstract for TR-466 72KB

    https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr466

    Abstract for TR-466 Toxicology and Carcinogenesis Studies of Ethylbenzene in F344/N Rats and B6C3F1 Mice (Inhalation Studies) CASRN: 100-41-4 Chemical Formula: C8H10 Molecular ...

  5. Minutes: BSC TRRS; Dec. 11, 1996 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1996/dec/trrs11dec1996mins_508.pdf

    Chloroprene 126-99-8 Inhalation Cobalt Sulfate Heptahydrate 10026-24-1 Inhalation Ethylbenzene 100-41-4 Inhalation Isobutyraldehyde 78-84-2 Inhalation Oxazepam 604-75-1 Feed ...

  6. Abstract for TOX-10 61KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox010

    0abs Abstract for TOX-10 Toxicity Studies of Ethylbenzene in F344/N Rats and B6C3F1 Mice (Inhalation Studies) CASRN: 100-41-4 Chemical Formula: CH2CH3 Molecular Weight: 106.16 ...

  7. Target Organs and Levels of Evidence for TR-466 59KB

    https://ntp.niehs.nih.gov/data/tr/400s/tr466levels

    Target Organs and Levels of Evidence for TR-466 Toxicology and Carcinogenesis Studies of Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) Chemical ...

  8. Abstract for TR-327 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr327

    14% p-Xylene, 9% o-Xylene, and 17% Ethylbenzene) in F344/N Rats and B6C3F1 Mice ... contains the three isomeric forms and ethylbenzene (percentage composition shown above). ...

  9. TR-327: Xylenes (Mixed) (60%m-Xylene, 14%p-Xylene, 9%o-Xylene... 8.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr327.pdf

    XYLENES (MIXED) (60%m-XYLENE, 14% p-XYLENE, 9% o-XYLENE, and 17% ETHYLBENZENE) (CAS NO. ... STUDIES OF XYLENES (MIXED) (60%m-XYLENE, 14%p-XYLENE, 9% 0-XYLENE, and 17% ETHYLBENZENE) ...

  10. Background Document: RoC: Styrene; 2010 4.3MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/styrene_final_508.pdf

    ... chemicals, including benzene, toluene, ethylbenzene, and various solvents, and the cohorts ... Figure 2-1. Synthesis of styrene from ethylbenzene and polymerization of styrene to form ...

  11. Styrene Expert Panel Report Part A; RoC; July 21-22, 2008 756KB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/styrene_panelreportparta_508.pdf

    ... Typical impurities are ethylbenzene (85 ppm maximum), polymer content (10 ppm maximum); ... styrene, toluene, benzene, and unreacted ethylbenzene, is fractionally condensed.] . ...

  12. RoC Concept: Cumene 251KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/concepts/cumeneconcdocroc8-30-12_508.pdf

    It has a gasoline-like odor and can exist as a vapor in ambient air. Cumene is structurally similar to benzene, toluene, styrene, xylene, and ethylbenzene. It is a high production ...

  13. Minutes: BSC TRRS; Nov. 19, 1990 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1990/nov/trrs19nov1990mins_508.pdf

    i d e Antimony Potass.ium T a r t r a t e C a s t o r O i 1 Cresol s Ethylbenzene CAS No. ... u d i e s 28300-74-5 8001-79-4 1319-77-3 100-41-4 I n f o r m a t i o n Reports Body ...

  14. Agenda: RoC Styrene Expert Panel Meeting; July 21-22, 2008 105KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2008/expertpanelmtgs/styrene_agenda20080722.pdf

    James McGraw, International Institute of Synthetic Rubber Producers Dr. James Bus, American Chemistry Council, Ethylbenzene Panel Dr. Larry Andrews, SB Latex Council Dr. Thomas ...

  15. TOX-35: Chemical Mixture of 25 Groundwater Contaminants 11.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox35.pdf

    ... 0 .75 2 .5 Di(2-ethylhexyl) phthalate Ethylbenzene 0 .65 0 .009 0 .03 0 .09 0 .3 Lead 37 ... 0 .13 0 .0005 0 .0015 0 .0045 0 .015 Ethylbenzene 100-41-4 0 .65 0 .009 0 .03 0 .09 0 .3 ...

  16. Exploring Mechanistic Toxicity of Mixtures Using PBPK Modeling... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-ruiz-508.pdf

    Modified from https://www.systemsbiology.org.au/ Toluene, Ethylbenzene and Xylene ⤠... a recoded PBPK model for toluene, ethylbenzene and xylene (TEX). ⤠Explore the use ...

  17. CERHR Monograph: Potential Human Reproduction Effects of Styrene 6.0MB

    https://ntp.niehs.nih.gov/ntp/ohat/styrene/styrene_monograph.pdf

    ... Styrene. is. manufactured. from. ethylbenzene. primarily. by. two. methods.. In. the. most. com- mon. method,. ethylbenzene. is. dehydrogenated. using.steam.and.an.iron/zinc/...

  18. Studies on Historical Control Reports for NIH-07 Feed 312KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/nih-07_1999/histcont_1999_by_list_of_studies_508.pdf

    Rats Fischer344 Inhalation Air Ethylbenzene Rats Fischer344 Inhalation Air ... bromide Mice B6C3F1 Inhalation Air Ethylbenzene Mice B6C3F1 Inhalation Air Isobutyl ...

  19. Minutes: BSC; June 17-18, 2014 290KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/june/minutes20140618_508.pdf

    ... carcinogenicity studies of benzene, toluene, ethylbenzene, xylenes, and related compounds. ... The purity and presence of ethylbenzene in the test agent will be a key issue. The ...

  20. Nose - Pigment - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/nose/Pigment

    Related Links: Nose - Foreign Material References: Nikula KJ, Sun JD, Barr EB, Bechtold WE, Haley PJ, Benson JM, Eidson AF, Burt DG, Dahl AR, RF Henderson RF, Chang IY, Mauderly ...

  21. Nose - Pigment 334KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/nose/pigment/nose-pigment-pdf_508.pdf

    ... Reference: Nikula KJ, Sun JD, Barr EB, Bechtold WE, Haley PJ, Benson JM, Eidson AF, Burt DG, Dahl AR, RF Henderson RF, Chang IY, Mauderly JL, Dieter MP, Hobbs CH. 1993. ...

  22. Presentation: Using Evidence-Based Toxicology to Evaluate AOPs 1.2MB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/hartung-508.pdf

    ... tool for the quality of toxicological data Available from AltWeb or ALTEX website y Challenges in Applying EB Approaches to Toxicolog . Diverse study types in toxicology . ...

  23. Novel Tools and Approaches Program; David Crizer; BSC; June 8... 1.7MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/june/presentations/nta_bsc_presentation_508.pdf

    ... Embryoid Bodies (EBs) for High-throughput Teratogen Screening . Viability assay . EB ... Prediction validation Human ESCs in 2D culture EB formed in 384 ULA well plate 21 ...

  24. RoC Profile: Benzene; 15th RoC 2021 110KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/benzene.pdf

    ... As a raw material, it is used in the synthesis of ethylbenzene (used to produce styrene) (53%), cumene (used to produce phenol and acetone) (22%), cyclohexane (12%), nitrobenzene ...

  25. Public Comments for Ongoing & Considered Health Effects Evaluations 91KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/comments

    ... Attachment 1: VCCEP Attachment 2: Appendices A-K Attachment 3: Appendices L-O Attachment 4: Appendices P-R Styrene Information and Research Center (SIRC) Ethylbenzene Cancer ...

  26. RoC Profile: Diepoxybutane; 15th RoC 2021 122KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diepoxybutane.pdf

    ... Chemical Sources International. http://www. chemsources.com/chemonline.html and search on butadiene diepoxide. Last accessed: 5/09. Henderson RF, Hahn FF, Barr EB, Belinsky SA, ...

  27. National Toxicology Program Toxicity Report Series 590KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox037.pdf

    ... Feed 92-3128 m-Cresol p-Cresol 10 Ethylbenzene Inhalation 92-3129 11 Antimony ... Edgewood Arsenal Technical Report EB-TR-76023. Department of the Army, Edgewood Arsenal, ...

  28. Combining NAM Data and IVIVE for Evaluating Potential Inhalation... 595KB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-chang-poster.pdf

    ... Methyl ethyl ketone 40 LDH leakage 1.1 0.6 Neuro. 1,1,1-Trichloroethane 152 Cell transformation 3.9 1.0 Neuro. Dichloromethane 535 Oxidative stress 5.9 2.8 Neuro. Ethylbenzene 500 ...

  29. RoC Monograph: Cumene; September 2013 2.3MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/cumene_508.pdf

    ... structurally similar to benzene, toluene, ethylbenzene, xylenes, and styrene (Figure 1-2). ... data from studies with styrene, ethylbenzene, coumarin, naphthalene, ...

  30. Moving Beyond Animal Data as the Gold Standard; Nicole Kleinstreuer... 3.4MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2018/september/presentations/06kleinstreuer_508.pdf

    ... Methods Variation in Classification Ex: ECHA Ocular Data CASRN ECHA Data 100-41-4 Not Irritating 100-41-4 Category 2A 100-74-3 Category 1 100-74-3 Category 2A 102-06-7 Category 1 ...

  31. TR-542: Cumene (CASRN 98-82-8) in F344/N Rats and B6C3F1 Mice... 9.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr542.pdf

    ... However, the NTP has con- ducted carcinogenicity studies of ethylbenzene (a struc- turally ... In contrast, ethylbenzene was not carcinogenic in male or female CD (Sprague-Dawley) rats ...

  32. TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB

    https://ntp.niehs.nih.gov/go/tr371

    ... include monomethylbenzene (toluene), ethylbenzene, 1-methylethylbenzene (cumene), and ... Ethylbenzene is in the short-term study phase by the National Toxicology Program (NTP), ...

  33. RoC Background Document: Disperse Blue I; Nov. 18-19, 1996 2.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/disperse_blue_508.pdf

    ... Blue 2GS Kayalon Fast Blue BR Microsetile Blue EB Miketon Fast Blue Miketon Fast Blue B Nacelan Blue G NCI-C54900 Neosetile Blue EB Nyloquinone blue 2j Nyloquinone Blue 2J Oracet ...

  34. Nomination Background: 2,3-Butanedione (CASRN: 431-03-8) 1.8MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/artificial_butter_flavoring_508be.pdf

    ... aromatics toluene, xylenes, and ethylbenzene and of methyl-substituted aromatic ... from butyric acid or are <<0.05. See Ethylbenzene/Xylenes.] 95-47-6 108-38-3 106-42-3 ...

  35. RoC Profile: Cumene; 15th RoC 2021 170KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cumene.pdf

    ... Based on a comparison with other compounds that also in- duced lung tumors in mice but not in rats, including ethylbenzene and styrene, some investigators (Cruzan et al. 2009, ...

  36. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf

    ... 0.00115 0.00131 0.00123 68.4 c Ethylbenzene 0.00118 0.00098 0.00108 83.1 Acetone ... 0.00123 0.00314 0.00178 0.000503 Ethylbenzene 0.00423 0.00280 0.00389 0.00338 ...

  37. Public Comment: 4-Methylimidazole; Joseph Rodricks; RoC; Sept... 157KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/rodricks20131018_508.pdf

    ... For example, Haseman found that the mouse lung tumor results in the 4-MeI bioassay were comparable to those observed in the NTP bioassays of ethylbenzene (TR-466), isobutyl nitrite ...

  38. ICCVAM 2018 Public Forum: International Activities 654KB

    https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2018/04-intlactivities.pdf

    ... Pt. .. .. . . f"\..~ . ~ l ; :uc C-:: : m:l .UE P1<.-.ntlen,Gow!pll0< ninoo. ;10ECD Bf.II.EB.E O_LLC~SLQBJ3ETJEaLnLES International Harmonization . OECD proposal co-led by US, EU, ...

  39. RoC Profile: Styrene; 15th RoC 2021 252KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/styrene.pdf

    ... Other typical impurities are ethylbenzene, polymer content, aldehydes, peroxides (as H 2 O ... of total world styrene production, involves cat- alytic dehydrogenation of ethylbenzene. ...

  40. Abstract for TOX-35 74KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox035

    ... 0.73 0.075 0.25 0.75 2.5 Di(2-ethylhexyl) phthalate 0.13 0.0005 0.0015 0.0045 0.015 Ethylbenzene 0.65 0.009 0.03 0.09 0.3 Lead 37.0 2.1 7 21 70 Mercury 0.34 0.017 0.05 0.17 0.5 ...

  41. NICEATM and ICCVAM Publications, 2020-2021 124KB

    https://ntp.niehs.nih.gov/iccvamreport/2021/reference/publications

    ... Ven Den Driessche G, Varnek A, Wang Z, Wedebye EB, Williams A, Xie H, Zakharov AV, Zheng Z, Judson RS. 2020. CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity. ...

  42. Public Comment: Cobalt and Certain Cobalt Compounds; Andrew Monnot... 491KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/publiccomm/monnot20131018_508.pdf

    ... Chern Res Toxicol8: 600-606. Mathiesen EB, Ahlborn A, Bermann G, and Lindgren JU. 1995. ... Orthopedics 14:137-142. Visuri T, Pukkala E, Paavolainen P, Pulkkinen P, and Riska EB. ...

  43. TR-271: HC Blue No. 1 (CASRN 2784-94-3) in F344/N Rats and B6C3F1Mice... 10.0MB

    https://ntp.niehs.nih.gov/go/tr271

    ... HC Blue No. 1,NTP TR 271 6 APPENDIXES (Continued) PAGE TABLE D2 APPENDIX E TABLE E l TABLE EB TABLE E3 TABLE E4 APPENDIX F TABLE F1 TABLE FB TABLE F3 TABLE F4 TABLE F5 TABLE F'8 ...

  44. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence P Clear Evidence P Clear Evidence P Clear Evidence TR-466 12/11/96 Ethylbenzene 100-41-4 P Clear Evidence SE Some Evidence SE Some Evidence SE Some Evidence TR-465 12/...

  45. RoC Profile: Captafol; 15th RoC 2021 155KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/captafol.pdf

    ... Tomlin CDS, ed. Hampshire, UK: British Crop Protection Council. pp. 140-141. Bernard BK, Gordon EB. 2000. An evaluation of the common mechanism approach to the Food Quality ...

  46. Short-Term Toxicity Reports 224KB

    https://ntp.niehs.nih.gov/publications/reports/tox

    ... Studies) 1992 Short-Term Toxicity TOX-10 PDF (3.47 MB) Toxicity Studies of Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) 1992 Short-Term ...

  47. Poster Abstracts: In Vitro to In Vivo Extrapolation for High... 132KB

    https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/posterabstracts-all-508.pdf

    ... The utility of the PBPK knowledgebase and web-based user interface was demonstrated using two case studies with ethylbenzene and gefitinib. Our PBPK knowledgebase is a novel tool ...

  48. Peer Review Report: RoC Peer Review; July 22, 2015 411KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/ntpresponsereportcobnov06_508.pdf

    ... Br J Radiol 47(554): 149-152. (as cited in Visuri et al. 2006) 23. Ruy RKN, Bovill EB, ... Acta Orthop 85(1): 32-38. (Follow-up of Mäkelä 2012.) 9. Mathiesen EB, Ahlbom A, Bermann ...

  49. RoC Profile: Diesel Exhaust Particulates; 15th RoC 2021 151KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dieselexhaustparticulates.pdf

    ... DNA and hemoglobin adducts and urinary 1-hydroxypyrene as markers of exposure. Toxicol Lett 86(1): 27-37. Nikula KJ, Snipes MB, Barr EB, Griffith WC, Henderson RF, Mauderly JL. ...

  50. RoC Profile: Haloacetic Acids; 15th RoC 2021 382KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/haloacetic_acids.pdf

    ... EB, Ayed A, et al. 2014a. Hepatoprotective activity of date fruit extracts against dichloroacetic acid-induced liver damage in rats. J Funct Foods 9: 119-130. El Arem A, Saafi EB, ...

 
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