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TR-212: Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats... 4.4MB
https://ntp.niehs.nih.gov/go/tr212
2 CARCINOGENESIS BIOASSAY OF DI(2-ETHYLHEXYL)ADIPATE (CAS NO. 103-23-1) F344 RATS AND B6C3F1 MICE (FEED STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...
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Di(2-ethylhexyl)adipate: Target Organs and Levels of Evidence... 57KB
https://ntp.niehs.nih.gov/data/tr/200s/tr212levels
6 Di(2-ethylhexyl)adipate: Target Organs and Levels of Evidence for TR-212 Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats and B6C3F1 Mice (Feed ...
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Abstract for TR-212 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr212
Abstract for TR-212 Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate in F344 Rats and B6C3F1 Mice (Feed Study) CASRN: 103-23-1 Chemical Formula: C22H42O4 Molecular Weight: 370.57 ...
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TR-213: Butyl Benzyl Phthalate (CASRN 85-68-7) in F344/N Rats... 4.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr213.pdf
... ate (chronic testing phase); di(2-ethylhexyl)adipate caused liver tumors in mice (NTP, ... chemicals: (CAS 9000-30-0) Guar gum (CAS 103-23-1 ) Di(2-ethylhexyl)adipate (CAS 117-81-7 ...
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Abstract for TR-274 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr274
... in the incidence of lymphomas and an increased incidence of carcinomas of the liver in female mice (both seen in this study) were observed in studies of di(2-ethylhexyl)adipate. ...
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TR-217: Di(2-ethylhexyl)phthalate (CASRN 117-81-7) in F344 Rats... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr217.pdf
... in rooms in which chronic feeding studies were being conducted on guar gum (CAS 9000-30-0), butyl benzyl phthalate (CAS 85-68-7), and di(2-ethylhexyl)adipate (CAS 103-23-1). ...
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TR-229: Guar Gum (CASRN 9000-30-0) in F344 Rats and B6C3F1Mice... 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr229.pdf
... which chronic feeding studies were being conducted on di(2-ethylhexyl)phthalate (CAS 117- 81-7), butyl benzyl phthalate (CAS 85-68-7), and di(2-ethylhexyl)adipate (CAS 103-23-1). ...
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TR-284: Diallylphthalate (CASRN 131-17-9) in F344/N Rats (Gavage... 8.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr284.pdf
... include di(2-ethylhexyl)phthalate,di(2-
ethylhexyl)adipate, and butyl benzyl phthalate. ... of Di(2-ethylhexy1)- adipate (CAS No. 103-23-1) in F344 Rats and B6C3F1 Mice (Feed Study). ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... P Clear Evidence N No Evidence N No Evidence TR-212 06/27/80 Di(2-ethylhexyl) adipate 103-23-1 N No Evidence N No Evidence P Clear Evidence P Clear Evidence TR-211 02/18/81 C.I. ...
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TR-266: Monuron (CASRN 150-68-5) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr266.pdf
... . 2HC1 4,4' -Oxydianiline Di(2-ethylhexyl)adipate Di(2-ethylhexyl)phthalate Locust ... Cinnamyl anthranilate 2,6-Toluenediamine . 2HC1 4,4' -Oxydianiline Di(2-ethylhexyl)adipate ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Technical Report TR-212 PDF (4.46 MB) Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats and B6C3F1 Mice (Feed Study) 1982 Technical Report TR-211 ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... I fluoride 3.13 4.22 245.2 117 Di(2-ethylhexyl)adipate 3.15 24.6 9117.7 270 ... 6.54 53.4 8854.8 117 Di(2-ethylhexyl)adipate 3.15 24.6 9117.7 162 ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... NTP, 1982. Carcinogenesis bioassay of di(2-ethylhexyl) adipate (CAS No. 103-23-1) in F344 ... 1982. Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats and ...
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CERHR Update on the Reproductive and Developmental Toxicity of... 4.5MB
https://ntp.niehs.nih.gov/ntp/ohat/phthalates/dehp/dehp-monograph.pdf
...ith.a.combination.of.DEHP.750.mg/kg.bw/day.plus.di(2-ethylhexyl)adipate.400.mg/kg.bw/day.. ....the.group.exposed.to.DEHP. plus.di(2-ethylhexyl)adipate..Testicular.testosterone.was.redu...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Technical Report TR-212 PDF (4.46 MB) Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats and B6C3F1 Mice (Feed Study) 1982 Technical Report TR-211 ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... I fluoride 7789-23-3 181.85 3.13 245.2 4.22 NA NA 58.1 4.22 117 Di(2-ethylhexyl)adipate 103-23-1 1167.52 3.15 9117.7 24.6 NA NA 370.64 24.6 270 Propionaldehyde 123-38-6 ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... Carcinogenicity TR-212 PDF (4.46 MB) Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CASRN 103-23-1) in F344 Rats and B6C3F1 Mice (Feed Study) 1982 Long-Term Carcinogenicity ...
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TR-429: Diethylphthalate (CASRN 84-66-2) in F344/N Rats and B6C3F1Mice... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr429.pdf
...(2-ethylhexyl)phthalate (DEHP; NTP, 1982a) and di(2-ethylhexyl)adipate (DEHA; NTP, 1982b). ... Carcinogenesis Bioassay of Di(2-Ethylhexyl)Adipate (CAS No. 103-23-1) in F344 Rats ...
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TR-274: Tris(2-ethylhexyl)phosphate (CASRN 78-42-2) In F344/N... 8.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr274.pdf
... trends in the incidences of neoplasms associated with ex- posure to tris(2-ethylhexyl)phosphate, di(2-
ethylhexyl)adipate, a n d di(2-ethylhexyll- phthalate is not yet known. ...
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TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr391.pdf
... However, studies o f several [di(2- compounds ethylhexyl) phthalate, di(2-ethylhexyl)adipate, 2- ethylhexyl sulfate] containing 2-ethylhexanol, the anticipatedmetabolite o f TEHP, ...
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TR-573: Styrene-acrylonitrile trimer in F344/N Rats (Perinatal... 5.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr573_508.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDY OF STYRENE-ACRYLONITRILE TRIMER IN F344/N RATS (PERINATAL AND POSTNATAL FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM ...
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TOX-62: WY-14,643 (CASRN 50892-23-4) 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox062.pdf
... increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate. Jpn. ...
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TR-423: 3,4-Dihydrocoumarin (CASRN 119-84-6) in F344/N Rats and... 24.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr423.pdf
NATEONALTOX~ICOLOG~ ~ O ~ , ' J I T ~ I ~ I ~ e ~ ~ e s ~ 4 ~ '~©XEC©L©G~ ~ D CA~,~CffH©GEHESES $TUDEE$ OF 3 ~ 4 o D H T Y D ~ © C © U ~ ~ (CAS H©o M9o~4o~) EH F344/H ~L~T$ ...
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TR-458: Butyl Benzyl Phthalate (CASRN 85-68-7) in F344 Rats ... 12.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr458.pdf
... Carcinogenesis Bioassay of, Di(2-ethylhexyl)adipate (CAS No. 103-23-1) in F344 Rats and B6C3Fl Mice (Feed Study). Technical Report Series No. 2 12. NM Publication No.81-1768. U.S . ...
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TOX-30: Dibutyl Phthalate (CASRN 84-74-2) 3.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox030.pdf
... National Academy Press, Washington, DC. NATIONAL TOXICOLOGY PROGRAM (NTP) (1982a). Carcinogenesis Bioassay of Di(2-ethylhexyl)adipate (CAS No. 103-23-1) in F344 Rats and B6C3F Mice ...
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TR-365: Pentaerythritol Tetranitrate (CASRN 78-11-5) with 80D... 22.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr365.pdf
... 0/48 Butyl benzyl phthalate 0/47 Dt(2-ethy lhexy l)phthalate 0/48 DI(2-ethylhexyl)adipate 0150 Guargum 0/48 Locust bean gum 0150 Gum arabic <cl 1/49 Agar 0/49 Tara gum ...
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TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf
... (Gavage) 210 1,2-Dibromoethane 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butyl Benzyl Phthalate 214 Caprolactam 215 Bisphenol A 216 ...
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TR-320: Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1Mice... 11.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr320.pdf
... (Gavage) 210 1,2-Dibromoethane (Inhalation) 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butylbenzyl Phthalate 214 Caprolactam 215 Bisphenol A 216 ...
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TR-335: C.I. Acid Orange 3 (CASRN 6373-74-6) in F344/N Rats and... 12.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr335.pdf
... Monohydrochloride 211 C.I. Acid Orange 10 287 Dimethyl Hydrogen Phosphite 212 Di(2-ethylhexyl)adipate 288 1,3-Butadiene 213 Butylbenzyl Phthalate 289 Benzene 214 Caprolactam 291 ...
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TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf
... (Gavage) 210 1,2-Dibromoethane (Inhalation) 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butylbenzyl Phthalate 214 Caprolactam 215 BisphenolA 216 11 ...
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TR-323: Dimethyl Methylphosphonate (CASRN 756-79-6) in F344/N... 9.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr323.pdf
... (Gavage) 210 1,2-Dibromoethane (Inhalation) 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butylbenzyl Phthalate 214 Caprolactam 215 Bisphenol A 216 11 ...
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TR-339: 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr339.pdf
... <Rats) 211 CJ. Acid Orange 10 285 C.!. Basic Red 9 Monohydrochloride 212 Di(2-ethylhexyl)adipate 287 Dimethyl Hydrogen Phosphite 213 Butylbenzyl Phthalate 288 1,3-Butadiene ...
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TR-373: Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and... 21.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr373.pdf
... (Gavage) 210 1,2-Dibromoethane (Inhalation) 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butylbenzyl Phthalate 214 Caprolactam 215 BisphenolA 216 ...
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TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB
https://ntp.niehs.nih.gov/go/tr385
... (Gavage) 210 1,2-Dibromoethane 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butyl Benzyl Phthalate 214 Caprolactam 215 Bisphenol A 216 ...
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TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf
... (Gavage) 210 1,2-Dibromoethane 211 C.I. Acid Orange 10 212 Di(2-ethylhexyl)adipate 213 Butyl Benzyl Phthalate 214 Caprolactam 215 Bisphenol A 216 ...
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TR-384: 1,2,3-Trichloropropane (CASRN 96-18-4)in F344 Rats and... 5.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr384.pdf
... 278 2,6-Xylidine 211 C.I. Acid Orange 10 279 Amosite Asbestos 212 Di(2-ethylhexyl)adipate 280 Crocidolite Asbestos 213 Butyl Benzyl Phthalate 281 HC Red No. 3 214 ...
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ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... 370.33 9 3333.0 3.24 1199.9 Kelthane 370.48 0.012 4.4 1.55 574.2 Di(2-ethylhexyl)adipate 370.64 3.15 1167.5 24.6 9117.7 Ioxynil 370.91 0.11 40.8 0.3 111.3 Heptachlor ...