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Target Organs and Levels of Evidence for TR-394 52KB
https://ntp.niehs.nih.gov/data/tr/300s/tr394levels
Toxicology and Carcinogenesis Studies of Acetaminophen (CASRN 103-90-2) in F344 Rats and ... Acetaminophen (4-hydroxyacetanilide) 103-90-2 11/19/1990 Dosed-Feed R&M:0,.06,.3,.6%/...
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Abstract for TR-394 58KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr394
Toxicology and Carcinogenesis Studies of Acetaminophen in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 103-90-2 Chemical Formula: C8H9NO2 Molecular Weight: 151.16 Synonyms/...
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Abstract for RACB83079 55KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb83079
Acetaminophen: Reproduction and Fertility Assessment in CD-1 Mice When Administered in the Feed CASRN: 103-90-2 Chemical Formula: C8H9NO2 Molecular Weight: 151.16 Report Date: Nov. ...
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Developmental Neurotoxicity Screening Assay Chemical List | National... 411KB
https://www.niehs.nih.gov/research/atniehs/dtt/strategic-plan/health/developmental/chemical-list
... Omeprazole Neg Control 14611-52-0 DTXSID9044584 Selegiline hydrochloride Neg Control 103-90-2 DTXSID2020006 Acetaminophen (4-hydroxyacetanilide) (paracetamol) Neg Control ...
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TR-394: Acetaminophen (CASRN 103-90-2) in F344 Rats and B6C3F1Mice... 14.2MB
https://ntp.niehs.nih.gov/go/tr394
TOXICOLOGY AND CARCINOGENESIS STUDIES OF ACETAMINOPHEN (CAS NO. 103-90-2) IN F344/N RATS ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF ACETAMINOPHEN (CAS NO. 103-90-2) IN F344/N RATS ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... NE No Evidence SE Some Evidence TR-394 11/19/90 Acetaminophen (4-Hydroxyacetanilide) 103-90-2 NE No Evidence EE Equivocal Evidence NE No Evidence NE No Evidence TR-393 04/26/90 ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... 6.66 165.4 2.9 113 1 Acetaminophen 103-90-2 409.70 2.71 2403.8 15.9 338.6 2.24 ... 19.6 158.52 14.2 113 1 Acetaminophen 103-90-2 409.70 2.71 2403.8 15.9 338.6 2.24 ...
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ICCVAM Test Method Evaluation Report: In Vitro Cytotoxicity Test... 14.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/at-tmer-complete.pdf
... NHK IC 50 mg/kg mmole/kg µg/mL mM µg/mL mM 2000 < LD 50 ≤5000 mg/kg Acetaminophen 103-90-2 2404 15.90 47.66 0.3152 518.0 3.426 Potassium chloride 7447-40-7 2602 34.90 3555 ...
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ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... in NHK Assay (µg/mL) Acetaminophen 103-90-2 99 Sigma 8.1 4.7-1000 7.7 11.8-4000 ... f Mechanism of Lethaliy f Acetaminophen 103-90-2 2404 151.20 Organic compound; Amide ...
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MFDS NAMs Report: Regulatory Acceptance and Research Outcomes 20.5MB
https://ntp.niehs.nih.gov/sites/default/files/2024-01/MFDS_NAMs_Report-2023-508.pdf
... Image analysis for acetaminophen (APAP)-induced liver necrosis in SD rat using ... histopathology analysis of APAP-induced rat liver injury in preclinical ...
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Public Health Impact 1.9MB
https://ntp.niehs.nih.gov/media/impact
... National Toxicology Program (NTP). 1991. Acetaminophen (103-90-2). Chemical Effects in ... studies of acetaminophen (CASRN 103-90-2) in F344/N rats and B6C3F1 mice (feed studies). ...
