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73 results found for "104-55-2".
  1. TR-514: trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371... 8.5MB

    https://ntp.niehs.nih.gov/go/tr514

    THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF trans-CINNAMALDEHYDE (MICROENCAPSULATED) (CAS ... NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF trans-CINNAMALDEHYDE ...

  2. Nomination Background: Cinnamaldehyde (CASRN: 104-55-2) 2.0MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/cinnamaldehyde_508.pdf

    PROCESS OF THE NATIONAL TOXICOLOGY PROGRAM EXECUTIVE SUMMARY OF DATA CINNAMALDEHYDE ... Exposure to Cinnamaldehyde results primarily from its widespread use as a flavor and ...

  3. Cinnamaldehyde 10007-L 23KB

    https://ntp.niehs.nih.gov/go/ts-10007-l

    Cinnamaldehyde 10007-L CASRN: 104-55-2 Related: TRANS-CINNAMALDEHYDE (14371-10-9) Formula: C9-H8-O Synonyms/Common Names Cinnamic aldehyde 3-Phenyl-2-propenal Short-Term Toxicity 2 ...

  4. trans-Cinnamaldehyde M88146 23KB

    https://ntp.niehs.nih.gov/go/ts-m88146

    trans-Cinnamaldehyde M88146 CASRN: 14371-10-9 Related: CINNAMALDEHYDE (104-55-2) Formula: C9-H8-O Synonyms/Common Names 2-Propenal, 3-phenyl-, (E)- (9CI) Short-Term Toxicity 2 ...

  5. Nomination Summary for Cinnamaldehyde (N89208) 19KB

    https://ntp.niehs.nih.gov/go/nm-n89208

    Cinnamaldehyde (N89208) Nominated Substances: Cinnamaldehyde Nomination Date: 01/00/1989 Nominator: FDA Rationale: Concern about possible carcinogenicity of the cinnamyl moiety and ...

  6. Nomination Summary for Cinnamaldehyde (N79346) 19KB

    https://ntp.niehs.nih.gov/go/nm-n79346

    Cinnamaldehyde (N79346) Nominated Substances: Cinnamaldehyde Nomination Date: 09/11/1980 Nominator: FDA, NCI, NIEHS, OSHA Rationale: High and continuous exposure as main ingredient ...

  7. alpha-Methyl cinnamaldehyde M200070 20KB

    https://ntp.niehs.nih.gov/go/ts-m200070

    alpha-Methyl cinnamaldehyde M200070 CASRN: 101-39-3 Formula: C10-H10-O Synonyms/Common Names alpha-methylcinnamic aldehyde 2-Propenal, 2-methyl-3-phenyl- (9CI) Genetic Toxicology ...

  8. Abstract for TR-514 32KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr514/index.html

    Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde in F344/N Rats and B6C3F1 ... Names: trans-Benzenepropenal; (E)-cinnamaldehyde; cinnamaldehyde; trans-cinnamic ...

  9. Minutes: BSC TRRS; Sept. 5, 2002 128KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/trrs/2002/sept/trrs5sept2002mins_508.pdf

    .........6 V. trans-Cinnamaldehyde......The motion was approved unanimously with 10 votes. trans-Cinnamaldehyde Dr. Hooth, NIEHS, ...

  10. Nomination Summary for Genotoxic potential of flavoring agents... 37KB

    https://ntp.niehs.nih.gov/go/nm-n81302

    Cadinene, Carveol, Carvyl acetate, Cinnamaldehyde ethylene glycol acetal, Citral, ... Methyl anthranilate, alpha-Methyl cinnamaldehyde, Musk ambrette, Musk ketone, ...

  11. Target Organs and Levels of Evidence for TR-514 20KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr514levels/index.html

    Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN ... Levels Study Laboratory trans-Cinnamaldehyde 14371-10-9 09/05/2002 ...

  12. TR-514: Data 24KB

    https://ntp.niehs.nih.gov/data/tables/tr/500s/tr514/index.html

    5 TR-514: Data TR-514 Trans-Cinnamaldehyde Pathology Tables - Rats P03 - Incidence Rates of Non-Neoplastic Lesions - 2 year study P04 - Neoplasms by Individual Animal - 2 year ...

  13. P08: Statistical Analysis of Primary Tumors for Rats (99023-03... 181KB

    https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/99023_tables/03p08.pdf

    ALL ROUTES 88138-03 -- Benzophenone (ORAL FEED) 56111-03 -- trans-Cinnamaldehyde (ORAL FEED) 05174-05 -- Cresols (ORAL FEED) 96011-05 -- Cumene (INHALATION AIR) 93026-07 -- Decalin ...

  14. Historical Controls: All Routes and Vehicles for Mice; Studies... 255KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/m_hcrpt_allrte2006_508.pdf

    .../24/97 728 100(1) 91(705) 46.0 trans-Cinnamaldehyde Battelle Columbus Laboratory .../25/97 733 100(5) 84(711) 45.6 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  15. Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf

    .../08/97 731 100(3) 60(689) 487.9 trans-Cinnamaldehyde Battelle Columbus Laboratory .../09/97 735 100(5) 70(706) 337.8 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  16. Historical Controls: All Routes and Vehicles for Mice; Studies... 317KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20070300_508.pdf

    .../24/97 728 100(1) 91(705) 46.0 trans-Cinnamaldehyde Battelle Columbus Laboratory .../25/97 733 100(5) 84(711) 45.6 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  17. Historical Controls: All Routes and Vehicles for Rats; Studies... 252KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20070300_508.pdf

    .../08/97 731 100(3) 60(689) 487.9 trans-Cinnamaldehyde Battelle Columbus Laboratory .../09/97 735 100(5) 70(706) 337.8 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  18. Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf

    ... 4J SSL 1.41 - 73.1% 05/18/12 H 2 O 0.003% 6J SSL 2.29 + 81.9% 05/18/12 2 Cinnamaldehyde CA 104-55-2 SAFC EtOH 0.6% 4.34 + 32.5% 03/08/12 EtOH, H2O C 9 H 8 O 132.16 liquid ...

  19. ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf

    ... Phenols 0.8 (6.7) 1.081 (4.0) trans-Cinnamaldehyde Food additive; Fragrance agent ... 17.00, 17.00, 17.60, 20.00 trans-Cinnamaldehyde (4,1) AOO 3.37, 3.50, 4.11, 5.86 ...

  20. Management Status Report: Appendix 202KB

    https://ntp.niehs.nih.gov/go/msr-20

    ...,3-Trimethyl-2-oxabicyclo(2.2.2)octane 470-82-6 GAV R2 M3 Cinnamaldehyde Cinnamic aldehyde 3-Phenyl-2-propenal 104-55-2 FEED R2 M3 trans-Cinnamaldehyde 2-Propenal, 3-phenyl-, (E)- ...

  21. Nomination Background: Methyl trans-styryl ketone (CASRN: 1896... 758KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/msk_508.pdf

    ... Cinnamaldehyde has been studied for evidence of mutagenic or carcinogenic potency in a ... In the DCE short-term testing program, trans-cinnamaldehyde tested negative in an Ames ...

  22. Management Status Report Produced from NTP Chemtrack System 311KB

    https://ntp.niehs.nih.gov/publications/msr/msr.pdf

    ... C.I. Disperse Yellow 3 2832-40-8 42 16 1,8-Cineol 470-82-6 52 * 1,8-Cineol 470-82-6 52 * Cinnamaldehyde 104-55-2 52 * trans-Cinnamaldehyde 14371-10-9 42 16 trans-Cinnamaldehyde ...

  23. Substance Search 453KB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/status/index.html

    ... C.I. Disperse Red 60 C.I. Disperse Yellow 3 C.I. Food Red 1 1,8-Cineol Cinnamaldehyde trans-Cinnamaldehyde Cinnamyl anthranilate C.I. Pigment Green 36 C.I. Pigment Orange 43 C.I. ...

  24. Application of CATMoS to Ecological Risk Assessment 2.4MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2021/ppt/2021_sacatm_s2b-1_mansouri_v3_508.pdf

    ... 104-55-2 Acrolein 107-02.8 linalool 78.70.6 Union or lnter~ection Union Chemical Inp ut Select Ch emicals Quick List CASRN User CASRNs 104-55-2 78 -70- 6 ...

  25. Michelle J. Hooth, Ph.D., D.A.B.T. - Office of Program Operations 110KB

    https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/michelle/index.cfm

    ... D. P., Fuciarelli, A. F., Graves, S. W., Johnson, J. D. and Bucher, J. R. (2004) Toxicology and carcinogenesis studies of microencapsulated trans-cinnamaldehyde in rats and mice. ...

  26. NTP Technical Reports Index 282KB

    https://ntp.niehs.nih.gov/data/tr/index.html

    ... 05/22/03 Propylene Glycol mono- t-Butyl Ether 57018-52-7 TR-514 09/05/02 trans-Cinnamaldehyde 14381-10-9 TR-513 09/05/02 Decalin 91-17-8 TR-512 09/05/02 Elmiron® 37319-17-8 ...

  27. Management Status Report: Reference 16 LT 375KB

    https://ntp.niehs.nih.gov/go/msr-16lt

    ...nyl)azo)phenyl)acetamide Yellow 3, C.I. Disperse 2832-40-8 FEED R2 M3 TR-222 trans-Cinnamaldehyde 2-Propenal, 3-phenyl-, (E)- (9CI) 14371-10-9 MICRO R2 M3 TR-514 Cinnamyl ...

  28. Nomination Background: 2,4-Decadienal, (E,E)-(9Ci) 575KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/decadienal_508.pdf

    ... Acta. 919(3):239- 244 Growcock, F.B., Frenier, W.W. and Andreozzi, P.A. (1989) Inhibition of steel corrosion in HCl by derivatives of cinnamaldehyde. Part II. Structure-activity ...

  29. Poster Abstracts: Workshop on Best Practices for Assessing the... 1.6MB

    https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acdabstracts.pdf

    ... Although there were some discrepancies for three reference chemicals, these were attributed to issues with solubility and stability of test material. Hexyl cinnamaldehyde, a ...

  30. Minutes: BSC; Dec. 13, 1996 288KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/archives/1996/december/19961213_bsc_508.pdf

    ... Schwetz discussed the rationale for study and status of NTP studies on D & C Yellow No. 11, t-butylhydroquinone, polyvinyl alcohol, cinnamaldehyde, and ethoxyquin. He noted the ...

  31. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... + Basketter et al. (1994); Basketter et al. (1996a) Cinnamic aldehyde// cinnamaldehyde 104-55-2 potential Michael- reactive agent fragrance// food additive (bakery series kit) ...

  32. Toxicology/Carcinogenicity 693KB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox/index.html

    ... Carcinogenicity TR-514 PDF (9MB) Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN 14381-10-9) in F344/N Rats and B6C3F1 Mice (Feed ...

  33. ICCVAM Evaluation of In Vitro Test Methods for Assessing Dermal... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/cwgfinal02/cwgfinal.pdf

    ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ...

  34. ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf

    ... the allergic potency of alpha-hexyl cinnamaldehyde (HCA) and 2- mercaptobenzothiazole ... or 5% cinnamic aldehyde (CASRN: 104-55-2) were used as positive controls (Idehara ...

  35. Nomination Background: 2,4-Hexadienal (CASRN: 142-83-6) 987KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/hexadienal_508.pdf

    ... London:The Richelieu Press, pp. 201,220. Growcock, F.B., Frenier, W.W. and Andreozzi, P.A. (1989) Inhibition of steel corrosion in HCl by derivatives of cinnamaldehyde. Part II. ...

  36. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/go/rr11

    ... g 99.8 Colorless Liquid Ambient Trans-Cinnamaldehyde (3- phenyl-2propanal) 1,2 BCBP7078V ... 126.58 Chrysene 218-01-9 228.29 Cinnamaldehyde 14371-10-9 132.16 Cycloheptane ...

  37. TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 9.7MB

    https://ntp.niehs.nih.gov/go/tr516

    ... Incidence: Feed Studies trans-Cinnamaldehyde 1/50 1/50 2/50 Citral 3/50 1/50 4/50 ... Incidence: Feed Studies trans-Cinnamaldehyde 1/50 0/50 1/50 Citral 0/50 0/50 0/50 ...

  38. Background Review Document: In Vitro Test Methods for Assessing... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/epis_brd0801.pdf

    ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ...

  39. TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB

    https://ntp.niehs.nih.gov/go/tr513

    ... Controls Given NTP-2000 Diet a trans-Cinnamaldehyde (feed) 0/100 0/100 0/100 Citral ... Controls Given NTP-2000 Diet a trans-Cinnamaldehyde (feed) 5/100 0/100 5/100 Citral ...

  40. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... (gavage) 0/50 2/50 0/50 trans-Cinnamaldehyde (feed) 0/100 0/100 0/100 Citral ... (gavage) 2/50 3/50 5/50 trans-Cinnamaldehyde (feed) 3/100 2/100 5/100 Citral ...

  41. TR-533: Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1Mice... 10.7MB

    https://ntp.niehs.nih.gov/go/tr533

    ... sulfone 0/50 trans-Cinnamaldehyde 0/100 2-Methylimidazole 0/49 ... sulfone 27/50 trans-Cinnamaldehyde 40/100 2-Methylimidazole 15/50 ...

  42. TOX-76: 2,4-Decadienal (CASRN 25152-84-5) 3.7MB

    https://ntp.niehs.nih.gov/go/tox076

    ... Inhibition of steel corrosion in HCl by derivatives of cinnamaldehyde. Part II: ... Nasal and other tumours in rats given 3,4,5-trimethyoxy-cinnamaldehyde, a derivative of ...

  43. TR-551: Isoeugenol (CASRN 97-54-1) in F344/N Rats and B6C3F1... 6.2MB

    https://ntp.niehs.nih.gov/go/tr551

    ... 1-propenyl analogs anethole, 3N-hydroxy-trans-anethole, isosafrole, and trans-cinnamaldehyde did not induce hepatic tumors, but cis- and trans-asarone were active; ...

  44. Nomination Background: Estragole (CASRN: 140-67-0) 1.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/estragole_508.pdf

    ... H 16 O 3 MW: 208.26 density: 1.073 Practically insoluble in water H CHO H Cinnamaldehyde (104-55-2) C 9 H 8 O MW: 132.16 d 25 25 : 1.048-1.052 m.p.: -7.5 b.p.: 246.0 Dissolves in ...

  45. Study Reports 606KB

    https://ntp.niehs.nih.gov/publications/reports/index.html

    ... Technical Report TR-514 PDF (9MB) Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN 14381-10-9) in F344/N Rats and B6C3F1 Mice (Feed ...

  46. Minutes: BSC; Sept. 17, 2002 762KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/archives/2002/september/20020917bscsummmins_508.pdf

    ... in female rats and male mice. . trans-Cinnamaldehyde - used in flavors and fragrances - exposure by microencapsulation in feed - no evidence in male and female rats or mice. ...

  47. Performance Standards for In Vitro Test Methods for Skin Corrosion 6.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/ps/ps044510.pdf

    ... acid NA NC NC 3.7 Chromium(III) fuoride 7788-97-8 acid derivative 97 NC NC 3.9 Cinnamaldehyde 14371-10-9 electrophile 100 NC NC 3.9 Ethyl triglycol methacrylate 39670-09-2 acid ...

  48. ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf

    ... alcohol - 104-54-1 134.18 2.29 Solid Alcohols Gerberick Cinnamic aldehyde Cinnamaldehyde 104-55-2 132.16 2.29 Liquid Aldehydes Gerberick cis-4-Cyano-4-[3- (cyclopentyloxy)-4- ...

  49. TR-505: Citral (Microencapsulated) (CASRN 5392-40-5) in F344... 10.8MB

    https://ntp.niehs.nih.gov/go/tr505

    ... (1994). Comparison of the toxicity of cinnamaldehyde when administered by ... Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, cur- cumin, ethacrynic acid, ...

  50. Application of Non-animal Test Methods and Defined Approaches... 22.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/it/niceatm-it-report-june2020-final-wappx-508.pdf

    ... Lysine peptide (Ac-RFAAKAA-COOH), Store at ≤-20˚C, (RS synthesis, Louisville, KY) . Cinnamic Aldehyde, ~95% purity, (CAS# 104-55-2, Sigma-Aldrich #W228613 or equivalent) ...

 
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