Skip to Main Navigation Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

We welcome your feedback!

Contact us with your comments.

QUICK TIPS
 
of 2

Refine

  • Categories
  • Content Type
  • Reports and Publications
  • Years
  • Formats

Search suggestions for "104-55-2".

  1. CEBS Data Related to Cinnamaldehyde (104-55-2) https://cebs.niehs.nih.gov/cebs/test_article/104-55-2


56 results found for "104-55-2".

  1. TR-514: trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371... 7.2MB

    https://ntp.niehs.nih.gov/go/tr514

    NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRANS-CINNAMALDEHYDE ... AND CARCINOGENESIS STUDIES OF trans-CINNAMALDEHYDE (MICROENCAPSULATED) (CAS NO. ...

  2. Abstract for TR-514 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/tr514

    Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde in F344/N Rats and B6C3F1 ... Names: trans-Benzenepropenal; (E)-cinnamaldehyde; cinnamaldehyde; trans-cinnamic ...

  3. Target Organs and Levels of Evidence for TR-514 50KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr514levels

    Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN ... Levels Study Laboratory trans-Cinnamaldehyde 14371-10-9 09/05/2002 ...

  4. Minutes: BSC TRRS; Sept. 5, 2002 128KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2002/sept/trrs5sept2002mins_508.pdf

    .........6 V. trans-Cinnamaldehyde......The motion was approved unanimously with 10 votes. trans-Cinnamaldehyde Dr. Hooth, NIEHS, ...

  5. Historical Controls: All Routes and Vehicles for Mice; Studies... 255KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2006/m_hcrpt_allrte2006_508.pdf

    .../24/97 728 100(1) 91(705) 46.0 trans-Cinnamaldehyde Battelle Columbus Laboratory .../25/97 733 100(5) 84(711) 45.6 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  6. Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf

    .../08/97 731 100(3) 60(689) 487.9 trans-Cinnamaldehyde Battelle Columbus Laboratory .../09/97 735 100(5) 70(706) 337.8 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  7. Historical Controls: All Routes and Vehicles for Mice; Studies... 317KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20070300_508.pdf

    .../24/97 728 100(1) 91(705) 46.0 trans-Cinnamaldehyde Battelle Columbus Laboratory .../25/97 733 100(5) 84(711) 45.6 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  8. Historical Controls: All Routes and Vehicles for Rats; Studies... 252KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20070300_508.pdf

    .../08/97 731 100(3) 60(689) 487.9 trans-Cinnamaldehyde Battelle Columbus Laboratory .../09/97 735 100(5) 70(706) 337.8 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  9. Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf

    ... 4J SSL 1.41 - 73.1% 05/18/12 H 2 O 0.003% 6J SSL 2.29 + 81.9% 05/18/12 2 Cinnamaldehyde CA 104-55-2 SAFC EtOH 0.6% 4.34 + 32.5% 03/08/12 EtOH, H2O C 9 H 8 O 132.16 liquid ...

  10. ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf

    ... Phenols 0.8 (6.7) 1.081 (4.0) trans-Cinnamaldehyde Food additive; Fragrance agent ... 17.00, 17.00, 17.60, 20.00 trans-Cinnamaldehyde (4,1) AOO 3.37, 3.50, 4.11, 5.86 ...

  11. Application of CATMoS to Ecological Risk Assessment 2.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/2021/ppt/2021_sacatm_s2b-1_mansouri_v3_508.pdf

    ... 104-55-2 Acrolein 107-02.8 linalool 78.70.6 Union or lnter~ection Union Chemical Inp ut Select Ch emicals Quick List CASRN User CASRNs 104-55-2 78 -70- 6 ...

  12. Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf

    ... Human GHS LLNA GHS 2o3 pred. (hazard) ITS pred. (GHS) Benzylidene acetone* 122-57-6 Y 1A 1 1 1A Cinnamaldehyde* 104-55-2 Y 1A 1A 1 1A Diethyl maleate 141-05-9 N 1A 1B 1 1A DNCB* ...

  13. Validation of the Electrophilic Allergen Screening Assay (EASA... 1.3MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-gordon-poster.pdf

    ... Benzyl salicylate Neg/Pos/Pos Neg/Pos/Pos Neg/Pos/Pos Neg/Pos/Pos Pos Pos-Neg/Pos Cinnamaldehyde Pos/Pos/Pos Pos/Pos/Pos Pos/Pos/Pos Pos/Pos/Pos Pos Pos/Pos Imidazolidinyl urea ...

  14. Validation of the Electrophilic Allergen Screening Assay (EASA... 1.5MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-09/Reinke-WC12-poster-FD.pdf

    ... Metol (4-methyl amino phenol) Pos Pos Pos Pos Pos Pos/Pos 2-Mercaptobenzothiazole Pos Pos Pos Pos Pos Pos/Pos Benzyl salicylate Pos Pos Pos Pos Pos Pos-Neg/Pos Cinnamaldehyde Pos ...

  15. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence NE No Evidence P Clear Evidence P Clear Evidence TR-514 09/05/02 trans-Cinnamaldehyde 14381-10-9 NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-513 09/...

  16. Technical Reports 857KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-514 PDF (8.54 MB) Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371-10-9) in F344/N Rats and B6C3F1 Mice (Feed ...

  17. Study Reports 1.0MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-514 PDF (8.54 MB) Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371-10-9) in F344/N Rats and B6C3F1 Mice (Feed ...

  18. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... + Basketter et al. (1994); Basketter et al. (1996a) Cinnamic aldehyde// cinnamaldehyde 104-55-2 potential Michael- reactive agent fragrance// food additive (bakery series kit) ...

  19. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/research/apptoxres/cartox

    ... TR-514 PDF (8.54 MB) Toxicology and Carcinogenesis Studies of trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371-10-9) in F344/N Rats and B6C3F1 Mice (Feed ...

  20. ICCVAM Evaluation of In Vitro Test Methods for Assessing Dermal... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/cwgfinal02/cwgfinal.pdf

    ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ...

  21. ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf

    ... the allergic potency of alpha-hexyl cinnamaldehyde (HCA) and 2- mercaptobenzothiazole ... or 5% cinnamic aldehyde (CASRN: 104-55-2) were used as positive controls (Idehara ...

  22. NTP RR-11: The Chemical and Physical Characterization of Recycled... 2.1MB

    https://ntp.niehs.nih.gov/go/rr11

    ... g 99.8 Colorless Liquid Ambient Trans-Cinnamaldehyde (3- phenyl-2propanal) 1,2 BCBP7078V ... 126.58 Chrysene 218-01-9 228.29 Cinnamaldehyde 14371-10-9 132.16 Cycloheptane ...

  23. TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 5.9MB

    https://ntp.niehs.nih.gov/go/tr516

    ... Incidence: Feed Studies trans-Cinnamaldehyde 1/50 1/50 2/50 Citral 3/50 1/50 4/50 ... Incidence: Feed Studies trans-Cinnamaldehyde 1/50 0/50 1/50 Citral 0/50 0/50 0/50 ...

  24. Background Review Document: In Vitro Test Methods for Assessing... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/epis_brd0801.pdf

    ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ... methacrylate ELECTRO NC NC NC N/A 46 Cinnamaldehyde ELECTRO NC NC NC N/A 37 Sodium ...

  25. TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1 Mice... 3.8MB

    https://ntp.niehs.nih.gov/go/tr513

    ... Controls Given NTP-2000 Diet a trans-Cinnamaldehyde (feed) 0/100 0/100 0/100 Citral ... Controls Given NTP-2000 Diet a trans-Cinnamaldehyde (feed) 5/100 0/100 5/100 Citral ...

  26. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1 Mice (Dermal... 1.3MB

    https://ntp.niehs.nih.gov/go/tr518

    ... (gavage) 0/50 2/50 0/50 trans-Cinnamaldehyde (feed) 0/100 0/100 0/100 Citral ... (gavage) 2/50 3/50 5/50 trans-Cinnamaldehyde (feed) 3/100 2/100 5/100 Citral ...

  27. TR-533: Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1... 5.4MB

    https://ntp.niehs.nih.gov/go/tr533

    ... sulfone 0/50 trans-Cinnamaldehyde 0/100 2-Methylimidazole 0/49 ... sulfone 27/50 trans-Cinnamaldehyde 40/100 2-Methylimidazole 15/50 ...

  28. TOX-76: Toxicity Studies of 2,4-Decadienal (CASRN 25152-84-5... 2.5MB

    https://ntp.niehs.nih.gov/go/tox076

    ... Inhibition of steel corrosion in HCl by derivatives of cinnamaldehyde. Part II: ... Nasal and other tumours in rats given 3,4,5-trimethyoxy-cinnamaldehyde, a derivative of ...

  29. TR-551: Toxicology and Carcinogenesis Studies of Isoeugenol ... 3.5MB

    https://ntp.niehs.nih.gov/go/tr551

    ... 1-propenyl analogs anethole, 3N-hydroxy-trans-anethole, isosafrole, and trans-cinnamaldehyde did not induce hepatic tumors, but cis- and trans-asarone were active; ...

  30. Performance Standards for In Vitro Test Methods for Skin Corrosion 6.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/ps/ps044510.pdf

    ... acid NA NC NC 3.7 Chromium(III) fuoride 7788-97-8 acid derivative 97 NC NC 3.9 Cinnamaldehyde 14371-10-9 electrophile 100 NC NC 3.9 Ethyl triglycol methacrylate 39670-09-2 acid ...

  31. ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf

    ... alcohol - 104-54-1 134.18 2.29 Solid Alcohols Gerberick Cinnamic aldehyde Cinnamaldehyde 104-55-2 132.16 2.29 Liquid Aldehydes Gerberick cis-4-Cyano-4-[3- (cyclopentyloxy)-4- ...

  32. TR-505: Citral (Microencapsulated) (CASRN 5392-40-5) in F344... 2.1MB

    https://ntp.niehs.nih.gov/go/tr505

    ... (1994). Comparison of the toxicity of cinnamaldehyde when administered by ... Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, cur- cumin, ethacrynic acid, ...

  33. Application of Non-animal Test Methods and Defined Approaches... 22.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/it/niceatm-it-report-june2020-final-wappx-508.pdf

    ... Lysine peptide (Ac-RFAAKAA-COOH), Store at ≤-20˚C, (RS synthesis, Louisville, KY) . Cinnamic Aldehyde, ~95% purity, (CAS# 104-55-2, Sigma-Aldrich #W228613 or equivalent) ...

  34. ICCVAM Report: Corrositex: An In Vitro Method for Assessing Dermal... 5.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf

    ... 1 II II p18, 19 p89 1-3-70841, #20 37 Cinnamaldehyde Aldehyde Neat NA NA NC NC ECVAM ECVAM ... 171.67 171.52 1 7 1 . 6 0 0 . 1 1 cinnamaldehyde 14371-10-9 Source: ECVAM Validation ...

  35. Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf

    ... 5 1 V e h i c l e AOO AOO DMF C A S # 104-55-2 14371-10- 9 87-69-4 CHEMICAL STRUCTURE O ... Project No. 58H0508/062114. Report by BASF. ECPA. 2007b. Hexyl Cinnamaldehyde (HCA), ...

  36. TR-512: Elmiron (CASRN 37319-17-8) in F344/N Rats and B6C3F1... 4.7MB

    https://ntp.niehs.nih.gov/go/tr512

    ... (gavage) 2/50 23/50 14/50 32/50 trans-Cinnamaldehyde (feed) 0/100 14/100 13/100 26/100 ... (gavage) 0/50 4/50 4/50 trans-Cinnamaldehyde (feed) 4/100 1/100 5/100 Citral ...

  37. TR-535: 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and... 5.2MB

    https://ntp.niehs.nih.gov/go/tr535

    ... Feed Studies Benzophenone 19/50 trans-Cinnamaldehyde 21/100 Citral 24/100 ... Benzophenone 14/50 2/50 16/50 trans-Cinnamaldehyde 9/100 7/100 14/100 Citral 12/100 9/...

  38. TR-550: Toxicology and Carcinogenesis Studies of Cresols (CASRN... 2.4MB

    https://ntp.niehs.nih.gov/go/tr550

    ... Benzophenone 0/50 1/50 trans-Cinnamaldehyde 0/100 0/100 Cresols 0/50 0/50 ... Benzophenone 1/50 Chromium picolinate monohydrate 0/50 trans-Cinnamaldehyde 1/100 Cresols ...

  39. TOX-14: p-Chloro-a,a,a-Trifluorotoluene (CASRN 98-56-6) 2.2MB

    https://ntp.niehs.nih.gov/go/tox014

    ... and volatile chemicals such as trichloroethane, 2-ethylhexanol, cinnamaldehyde, and citral were successfully encapsulated using a starch-and-geletin mixture as the shell material. ...

  40. TOX-55: Toxicity Studies of trans-1,2-Dichloroethylene (CASRN... 1.7MB

    https://ntp.niehs.nih.gov/go/tox055

    ... Hébert, C.D., Yuan, J., and Dieter, M.P. (1994). Comparison of the toxicity of cinnamaldehyde when administered by microencapsulation in feed or by corn oil gavage. Food Chem. ...

  41. TR-378: Benzaldehyde (CASRN 100-52-7) in F344/N Rats and B6C3F1Mice... 14.1MB

    https://ntp.niehs.nih.gov/go/tr378

    ... num (cis-DDP) induced cell inactivation by al- dehydes: Protection by benzaldehyde (Benz); po- tentiation by cinnamaldehyde (Cinn). Proc. Annu. Meet. Am. Assoc. ...

  42. TR-523: Diisopropylcarbodiimide (CASRN 693-13-0) in F344/N Rats... 4.2MB

    https://ntp.niehs.nih.gov/go/tr523

    ... water) 8/50 2/50 1/50 11/50 trans-Cinnamaldehyde (feed) 5/100 0/100 0/100 5/100 Citral ... (drinking water) 1/50 trans-Cinnamaldehyde (feed) 2/100 Citral (feed) 6/99 ...

  43. RoC Background Document: Wood Dust; Dec. 13-14, 2000 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc10/wd_no_appendices_508.pdf

    ... Arbeitsmed Sozialmed Umweltmed 21:13-17. 74. Schoental,R. and S.Gibbard. (1972). Nasal and other tumours in rats given 3,4,5- trimethoxy-cinnamaldehyde, a derivative of ...

  44. TR-381: d-Carvone (CASRN 2244-16-8) in B6C3F1Mice (Gavage Studies... 6.3MB

    https://ntp.niehs.nih.gov/go/tr381

    ... (3:7), saturated, under nitrogen, and in the dark (solvent sys- tem 2). trans-Cinnamaldehyde was the reference standard, and visualization was with a spray of 5% (w/v) ...

  45. TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 2.9MB

    https://ntp.niehs.nih.gov/go/tr509

    ... Invest. 101, 1210-1218. Growcock, F.B., Frenier, W.W., and Andreozzi, P.A. (1989). Inhibition of steel corrosion in HCl by deriva- tives of cinnamaldehyde. Part II. ...

  46. Recommended Performance Standards for the LLNA 2.2MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf

    ... 47 X X X X X 2-Mercaptobenzothiazole 149-30-4 Sol DMF 1.7 1 X X X X Cinnamic aldehyde 104-55-2 Liq AOO 3.0 1 X Only need HCA (since it is an OECD positive control, and also because ...

  47. Historical Controls: By Route and Vehicle for Mice; Studies started... 775KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2006/m_hcrpt_rte2006_508.pdf

    .../24/97 728 100(1) 91(705) 46.0 trans-Cinnamaldehyde Battelle Columbus Laboratory .../25/97 733 100(5) 84(711) 45.6 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  48. Historical Controls: By Route and Vehicle for Rats; Studies started... 733KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2006/r_hcrpt_rte2006_508.pdf

    .../08/97 731 100(3) 60(689) 487.9 trans-Cinnamaldehyde Battelle Columbus Laboratory .../09/97 735 100(5) 70(706) 337.8 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  49. Historical Controls: By Route and Vehicle for Mice; Studies started... 790KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2007/m_hcrpt_rte20070300_508.pdf

    .../24/97 728 100(1) 91(705) 46.0 trans-Cinnamaldehyde Battelle Columbus Laboratory .../25/97 733 100(5) 84(711) 45.6 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

  50. Historical Controls: By Route and Vehicle for Rats; Studies started... 685KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/historical_controls/ntp2000_2007/r_hcrpt_rte20070300_508.pdf

    .../08/97 731 100(3) 60(689) 487.9 trans-Cinnamaldehyde Battelle Columbus Laboratory .../09/97 735 100(5) 70(706) 337.8 trans-Cinnamaldehyde Battelle Columbus Laboratory ...

 
of 2