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TR-579: N,N-Dimethyl-P-Toluidine (CASRN 99-97-8) in F344/N Rats... 11.5MB
https://ntp.niehs.nih.gov/go/tr579
N,N-DIMETHYL-p-TOLUIDINE (CAS NO. 99-97-8) IN F344/N RATS AND B6C3F1/N MICE (GAVAGE ... CARCINOGENESIS STUDIES OF N,N-DIMETHYL-p-TOLUIDINE (CAS NO. 99-97-8) IN F344/N RATS AND ...
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TR-145: 3-Chloro-p-Toluidine (CASRN 95-74-9) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr145.pdf
Series No. 145 BIOASSAY OF 3-CHLORO-p-TOLUIDINE FOR POSSIBLE CARCINOGENICITY CAS No. ... of Health BIOASSAY OF 3-CHLORO-p-TOLUIDINE FOR POSSIBLE CARCINOGENICITY ...
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Abstract for TR-579 87KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr579
Toxicology and Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine in F344/N Rats and ... dimethyl-4-toluidine; dimethyl-p-toluidine; N,N-dimethyl-p-tolylamine; ...
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3-Chloro-p-toluidine: Target Organs and Levels of Evidence for... 56KB
https://ntp.niehs.nih.gov/data/tr/100s/tr145levels
3 3-Chloro-p-toluidine: Target Organs and Levels of Evidence for TR-145 Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN 95-74-9) Chemical (Study Title) CASRN ...
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Abstract for TR-145 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr145
Abstract for TR-145 Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity CASRN: ... Full Report PDF Abstract 3-Chloro-p-toluidine, a dye intermediate and avicide, was ...
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Target Organs and Levels of Evidence for TR-579 63KB
https://ntp.niehs.nih.gov/data/tr/500s/tr579levels
Toxicology and Carinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N ... Levels Study Laboratory N,N-Dimethyl-p-toluidine 99-97-8 02/08/2012 Gavage R&M: 0, 6, ...
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Minutes: TR Panel; Feb. 8-9, 2012 371KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/minutes20120209_508.pdf
IV. Draft NTP Technical Report TR-579 on N,N-Dimethyl-p-toluidine (DMPT) ...... 5 V. ... Draft NTP Technical Report TR-579 on N,N-Dimethyl-p-toluidine (DMPT) Study Scientist Dr. ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 15KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont_2013_by_list_of_studies_508.pdf
Female Gavage Corn oil N,N-Dimethyl-p-toluidine Mice B6C3F1 Male and Female Gavage Corn ... Female Gavage Corn oil N,N-Dimethyl-p-toluidine Rats F 344/N Male and Female Gavage ...
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P08: Statisitical Analysis of Primary Tumors for Mice (20209... 159KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20209_tables/04_f1_m3_p08.pdf
CORN OIL) 20107-04 -- N,N-Dimethyl-p-toluidine (GAVAGE CORN OIL) 20320-04 -- ... ETHANOL) 20107-04 -- N,N-Dimethyl-p-toluidine (GAVAGE CORN OIL) 20009-04 -- ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf
Female Gavage Corn Oil N,N-Dimethyl-p-toluidine Mice B6C3F1 Male and Female Gavage Corn ... Female Gavage Corn Oil N,N-Dimethyl-p-toluidine Rats F 344/N Male and Female Gavage ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 113KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/ratsf344gavcornoil2013_508.pdf
727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Female Battelle Columbus Laboratory ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine NOTE: The text on page 2 ("Report ...
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Abstract for TR-34 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr034
...dipropyl-4-(trifluoromethyl) benzeneamine; a a a-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine; N,N,-dipropyl-4-trifluoromethyl-2,6-dinitroaniline; Treflan Report Date: 1978 Full ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 162KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/micegavcornoil2013_508.pdf
730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ...
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Historical Controls: Studies on 2014 Reports 20KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014_studylist_508.pdf
Corn oil Kava kava extract Mice B6C3F1 Male and Female Gavage Corn oil N,N-Dimethyl-p-toluidine Mice B6C3F1 Male and Female Gavage Corn oil Pentabromodiphenyl oxide (technical) (DE ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 260KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/path_micegavcornoil2014_508.pdf
730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ...
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Use of Toluidine in the Manufacture of Dyes 253KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/otolconsultant_report_508.pdf
... Instead p-toluidine is needed, along with aniline itself, in a ratio of 1:2. However, ... (-CH 3 ) group of p-toluidine becomes the central C-atom in the Magenta dye structure. ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 196KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/micegavcornoil.pdf
730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 166KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsgavcornoil.pdf
727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ...
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Agenda: TR Peer Review; Feb. 8-9, 2012 91KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/agenda20120209.pdf
Michelle Hooth, NIEHS/DNTP Draft NTP Technical Report TR-579 on N,N-Dimethyl-p-toluidine Study scientist: Dr. June Dunnick, NIEHS/DNTP Study pathologist: Dr. Amy Brix, Experimental ...
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P08: Statistical Analysis of Primary Tumors for Male & Female... 180KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20523_tables/04_f1_m3_p08.pdf
-- Metal Working Fluids: CIMSTAR 3800 (INHALATION AIR) 20107-04 -- N,N-Dimethyl-p-toluidine (GAVAGE CORN OIL) 20209-04 -- Pentabromodiphenyl Oxide (Technical) (DE 71) (GAVAGE ...
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Abstract for TOX-89 63KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox089
2-hydroxy-4-aminotoluene; 3-hydroxy-4-methylaniline; 2-hydroxy-p-toluidine; 2-methyl-5-aminophenol; 6-methyl-3-aminophenol Report Date: November 2015 Full ...
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TR Panel: Actions; TRs 574, 576, 578, 579, 580, GMM 14, GMM 16... 73KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/actions_feb2012.pdf
When completed, the technical reports will be published on the NTP website (http://ntp.niehs.nih.gov/go/reports). TR-579: N,N-Dimethyl-p-toluidine The Panel accepted (8 yes, 2 no, ...
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Eye, Vitreous - Proteinaceous Fluid - Nonneoplastic Lesion Atlas 286KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Vitreous-ProteinaceousFluid
National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N, N-Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage ...
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Eye, Vitreous - Proteinaceous Fluid 178KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/vtprotfl/eye-vitreous-proteinaceous-fluid_508.pdf
References: National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N,N- Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice ...
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Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 950KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_byroute_508.pdf
... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ...
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Historical Controls: Pathology Tables by Route/Vehicle for Fischer344N... 846KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_by_route_508.pdf
... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Female Battelle Columbus Laboratory ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 196KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014mice_all_routes_508.pdf
... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Evidence TR-579 02/08/12 N,N-Dimethyl-p-Toluidine 99-97-8 P Clear Evidence P Clear ... Evidence TR-145 06/29/78 3-Chloro-p-toluidine 95-74-9 N No Evidence N No Evidence N ...
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Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 1.2MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_byroute.pdf
... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ...
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Historical Controls: Pathology Tables by Route/Vehicle for Fischer... 1.2MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_byroute.pdf
... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 276KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_allroutes_508.pdf
... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 189KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_allroutes_508.pdf
... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ...
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Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 684KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014mice_byroute_508.pdf
... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf
... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ...
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Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf
... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and ... PDF (2.92 MB) Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN ...
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Eye, Lens - Cataract - Nonneoplastic Lesion Atlas 301KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Lens-Cataract
... National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N, N-Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage ...
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Eye, Lens - Cataract 425KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/lncat/eye-lens-cataract_508.pdf
... Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N,N- Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F 1 Mice (Gavage Studies). ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and ... PDF (2.92 MB) Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN ...
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RR-05: National Toxicology Program Approach to Genomic Dose-Response... 574KB
https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr05_508.pdf
... A, Travlos GS, Gerrish K, Michael Sanders J, Ton TV, Pandiri AR Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats. ...
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TOX-89: Toxicity Studies of 5-Amino-o-cresol (CASRN 2835-95-2... 2.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox089_508.pdf
... 3-hydroxy-4-methylaniline; 2-hydroxy-p-toluidine; 2-methyl-5-aminophenol; ... 2-hydroxy-p-toluidine; 2-methyl-5-aminophenol; 6-methyl-3-aminophenol. ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and ... PDF (2.92 MB) Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN ...
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Eye - Inflammation - Nonneoplastic Lesion Atlas 318KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Inflammation
... National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N, N-Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage ...
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Eye - Inflammation 955KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/inflamm/eye-inflammation_508.pdf
... Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N,N- Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage Studies). ...
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TR-129: Trimethylthiourea (CASRN 2489-77-2) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr129.pdf
... bis(N,N-dimethyl)-benzenamine (101-61-1); l-phenyl-2-thiourea (103-85- 5); 3-chloro-p-toluidine (95-74-9); dibutyltin diacetate (1067-33-0); 2-nitro-p-phenylenediamine (5307-14-2); ...
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TR-148: 1-Phenyl-2-thiourea (CASRN 103-85-5) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr148.pdf
... (1067- 33-0); 2-nitro-p-phenylenediamine (5307-14-2); 3-chloro-p-toluidine (95-74-9); 5-chloro-o-toluidine (95-79-4); and N-phenyl-p-phenylene- diamine hydrochloride (2198-59-6). ...
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TR-183: Dibutyltin Diacetate (CASRN 1067-33-0) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr183.pdf
... hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethyl- thiourea (2489-77-2); 2-nitro-p-phenylenediamine (5307-14-2); and 3-chloro-p-toluidine (95-74-9). ...
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TR-184: Nitrofen (CASRN 1836-75-5) 4.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr184.pdf
... All dosed and control rats were housed in a room with other rats receiving diets containing* 3-chloro-p-toluidine (95-74-9); 5-chloro- o-toluidine (95-74-4); 2-nitro-p-phenylenedia...
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TR-179: p-Quinone Dioxime (CASRN 105-11-3) 3.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr179.pdf
... hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); 2-nitro-p- phenylenediamine (5307-14-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-toluidine (95-74-9). ...
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TR-181: Michler's Ketone (CASRN 90-94-8) 3.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr181.pdf
... diamine hydrochloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethylthiourea (2489-77-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-toluidine (95-74-9). ...