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72 results found for "106-49-0".
  1. TR-579: N,N-Dimethyl-P-Toluidine (CASRN 99-97-8) in F344/N Rats... 11.5MB

    https://ntp.niehs.nih.gov/go/tr579

    N,N-DIMETHYL-p-TOLUIDINE (CAS NO. 99-97-8) IN F344/N RATS AND B6C3F1/N MICE (GAVAGE ... CARCINOGENESIS STUDIES OF N,N-DIMETHYL-p-TOLUIDINE (CAS NO. 99-97-8) IN F344/N RATS AND ...

  2. TR-145: 3-Chloro-p-Toluidine (CASRN 95-74-9) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr145.pdf

    Series No. 145 BIOASSAY OF 3-CHLORO-p-TOLUIDINE FOR POSSIBLE CARCINOGENICITY CAS No. ... of Health BIOASSAY OF 3-CHLORO-p-TOLUIDINE FOR POSSIBLE CARCINOGENICITY ...

  3. Abstract for TR-579 87KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr579

    Toxicology and Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine in F344/N Rats and ... dimethyl-4-toluidine; dimethyl-p-toluidine; N,N-dimethyl-p-tolylamine; ...

  4. 3-Chloro-p-toluidine: Target Organs and Levels of Evidence for... 56KB

    https://ntp.niehs.nih.gov/data/tr/100s/tr145levels

    3 3-Chloro-p-toluidine: Target Organs and Levels of Evidence for TR-145 Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN 95-74-9) Chemical (Study Title) CASRN ...

  5. Abstract for TR-145 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr145

    Abstract for TR-145 Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity CASRN: ... Full Report PDF Abstract 3-Chloro-p-toluidine, a dye intermediate and avicide, was ...

  6. Target Organs and Levels of Evidence for TR-579 63KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr579levels

    Toxicology and Carinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N ... Levels Study Laboratory N,N-Dimethyl-p-toluidine 99-97-8 02/08/2012 Gavage R&M: 0, 6, ...

  7. Minutes: TR Panel; Feb. 8-9, 2012 371KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/minutes20120209_508.pdf

    IV. Draft NTP Technical Report TR-579 on N,N-Dimethyl-p-toluidine (DMPT) ...... 5 V. ... Draft NTP Technical Report TR-579 on N,N-Dimethyl-p-toluidine (DMPT) Study Scientist Dr. ...

  8. Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 15KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont_2013_by_list_of_studies_508.pdf

    Female Gavage Corn oil N,N-Dimethyl-p-toluidine Mice B6C3F1 Male and Female Gavage Corn ... Female Gavage Corn oil N,N-Dimethyl-p-toluidine Rats F 344/N Male and Female Gavage ...

  9. P08: Statisitical Analysis of Primary Tumors for Mice (20209... 159KB

    https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20209_tables/04_f1_m3_p08.pdf

    CORN OIL) 20107-04 -- N,N-Dimethyl-p-toluidine (GAVAGE CORN OIL) 20320-04 -- ... ETHANOL) 20107-04 -- N,N-Dimethyl-p-toluidine (GAVAGE CORN OIL) 20009-04 -- ...

  10. Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf

    Female Gavage Corn Oil N,N-Dimethyl-p-toluidine Mice B6C3F1 Male and Female Gavage Corn ... Female Gavage Corn Oil N,N-Dimethyl-p-toluidine Rats F 344/N Male and Female Gavage ...

  11. Historical Controls: Pathology Tables by Gavage/Corn Oil for... 113KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/ratsf344gavcornoil2013_508.pdf

    727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Female Battelle Columbus Laboratory ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine NOTE: The text on page 2 ("Report ...

  12. Abstract for TR-34 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr034

    ...dipropyl-4-(trifluoromethyl) benzeneamine; a a a-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine; N,N,-dipropyl-4-trifluoromethyl-2,6-dinitroaniline; Treflan Report Date: 1978 Full ...

  13. Historical Controls: Pathology Tables by Gavage/Corn Oil for... 162KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/micegavcornoil2013_508.pdf

    730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ...

  14. Historical Controls: Studies on 2014 Reports 20KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014_studylist_508.pdf

    Corn oil Kava kava extract Mice B6C3F1 Male and Female Gavage Corn oil N,N-Dimethyl-p-toluidine Mice B6C3F1 Male and Female Gavage Corn oil Pentabromodiphenyl oxide (technical) (DE ...

  15. Historical Controls: Pathology Tables by Gavage/Corn Oil for... 260KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/path_micegavcornoil2014_508.pdf

    730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ...

  16. Use of Toluidine in the Manufacture of Dyes 253KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/otolconsultant_report_508.pdf

    ... Instead p-toluidine is needed, along with aniline itself, in a ratio of 1:2. However, ... (-CH 3 ) group of p-toluidine becomes the central C-atom in the Magenta dye structure. ...

  17. Historical Controls: Pathology Tables by Gavage/Corn Oil for... 196KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/micegavcornoil.pdf

    730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ...

  18. Historical Controls: Pathology Tables by Gavage/Corn Oil for... 166KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsgavcornoil.pdf

    727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ...

  19. Agenda: TR Peer Review; Feb. 8-9, 2012 91KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/agenda20120209.pdf

    Michelle Hooth, NIEHS/DNTP Draft NTP Technical Report TR-579 on N,N-Dimethyl-p-toluidine Study scientist: Dr. June Dunnick, NIEHS/DNTP Study pathologist: Dr. Amy Brix, Experimental ...

  20. P08: Statistical Analysis of Primary Tumors for Male & Female... 180KB

    https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20523_tables/04_f1_m3_p08.pdf

    -- Metal Working Fluids: CIMSTAR 3800 (INHALATION AIR) 20107-04 -- N,N-Dimethyl-p-toluidine (GAVAGE CORN OIL) 20209-04 -- Pentabromodiphenyl Oxide (Technical) (DE 71) (GAVAGE ...

  21. Abstract for TOX-89 63KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox089

    2-hydroxy-4-aminotoluene; 3-hydroxy-4-methylaniline; 2-hydroxy-p-toluidine; 2-methyl-5-aminophenol; 6-methyl-3-aminophenol Report Date: November 2015 Full ...

  22. TR Panel: Actions; TRs 574, 576, 578, 579, 580, GMM 14, GMM 16... 73KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/actions_feb2012.pdf

    When completed, the technical reports will be published on the NTP website (http://ntp.niehs.nih.gov/go/reports). TR-579: N,N-Dimethyl-p-toluidine The Panel accepted (8 yes, 2 no, ...

  23. Eye, Vitreous - Proteinaceous Fluid - Nonneoplastic Lesion Atlas 286KB

    https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Vitreous-ProteinaceousFluid

    National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N, N-Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage ...

  24. Eye, Vitreous - Proteinaceous Fluid 178KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/vtprotfl/eye-vitreous-proteinaceous-fluid_508.pdf

    References: National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N,N- Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice ...

  25. Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 950KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_byroute_508.pdf

    ... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052032004 ...

  26. Historical Controls: Pathology Tables by Route/Vehicle for Fischer344N... 846KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_by_route_508.pdf

    ... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Female Battelle Columbus Laboratory ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine NOTE: The text on page 2 ("Report ...

  27. Historical Controls: Pathology Tables for All Routes/Vehicles... 196KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014mice_all_routes_508.pdf

    ... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ...

  28. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence TR-579 02/08/12 N,N-Dimethyl-p-Toluidine 99-97-8 P Clear Evidence P Clear ... Evidence TR-145 06/29/78 3-Chloro-p-toluidine 95-74-9 N No Evidence N No Evidence N ...

  29. Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 1.2MB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_byroute.pdf

    ... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902006 ...

  30. Historical Controls: Pathology Tables by Route/Vehicle for Fischer... 1.2MB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_byroute.pdf

    ... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 059902005 ...

  31. Historical Controls: Pathology Tables for All Routes/Vehicles... 276KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_allroutes_508.pdf

    ... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ...

  32. Historical Controls: Pathology Tables for All Routes/Vehicles... 189KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_allroutes_508.pdf

    ... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ...

  33. Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 684KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014mice_byroute_508.pdf

    ... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Southern Research Institute 052020904 ...

  34. Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf

    ... 730 50(1) 34(665) 55.7 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ... 729 50(5) 43(715) 66.6 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000904 ...

  35. Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf

    ... 727 50(3) 37(702) 503.5 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ... 728 50(5) 33(704) 354.1 N,N-Dimethyl-p-toluidine Battelle Columbus Laboratory 052000903 ...

  36. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and ... PDF (2.92 MB) Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN ...

  37. Eye, Lens - Cataract - Nonneoplastic Lesion Atlas 301KB

    https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Lens-Cataract

    ... National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N, N-Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage ...

  38. Eye, Lens - Cataract 425KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/lncat/eye-lens-cataract_508.pdf

    ... Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N,N- Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F 1 Mice (Gavage Studies). ...

  39. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and ... PDF (2.92 MB) Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN ...

  40. RR-05: National Toxicology Program Approach to Genomic Dose-Response... 574KB

    https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr05_508.pdf

    ... A, Travlos GS, Gerrish K, Michael Sanders J, Ton TV, Pandiri AR Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats. ...

  41. TOX-89: Toxicity Studies of 5-Amino-o-cresol (CASRN 2835-95-2... 2.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox089_508.pdf

    ... 3-hydroxy-4-methylaniline; 2-hydroxy-p-toluidine; 2-methyl-5-aminophenol; ... 2-hydroxy-p-toluidine; 2-methyl-5-aminophenol; 6-methyl-3-aminophenol. ...

  42. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Carcinogenesis Studies of N,N-Dimethyl-p-Toluidine (CASRN 99-97-8) in F344/N Rats and ... PDF (2.92 MB) Bioassay of 3-Chloro-p-Toluidine for Possible Carcinogenicity (CASRN ...

  43. Eye - Inflammation - Nonneoplastic Lesion Atlas 318KB

    https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Inflammation

    ... National Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N, N-Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage ...

  44. Eye - Inflammation 955KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/inflamm/eye-inflammation_508.pdf

    ... Toxicology Program. 2012. NTP TR-579. Toxicology and Carcinogenesis Studies of N,N- Dimethyl-p-Toluidine (CAS No. 99-97-8) in F344/N Rats and B6C3F1/N Mice (Gavage Studies). ...

  45. TR-129: Trimethylthiourea (CASRN 2489-77-2) 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr129.pdf

    ... bis(N,N-dimethyl)-benzenamine (101-61-1); l-phenyl-2-thiourea (103-85- 5); 3-chloro-p-toluidine (95-74-9); dibutyltin diacetate (1067-33-0); 2-nitro-p-phenylenediamine (5307-14-2); ...

  46. TR-148: 1-Phenyl-2-thiourea (CASRN 103-85-5) 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr148.pdf

    ... (1067- 33-0); 2-nitro-p-phenylenediamine (5307-14-2); 3-chloro-p-toluidine (95-74-9); 5-chloro-o-toluidine (95-79-4); and N-phenyl-p-phenylene- diamine hydrochloride (2198-59-6). ...

  47. TR-183: Dibutyltin Diacetate (CASRN 1067-33-0) 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr183.pdf

    ... hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethyl- thiourea (2489-77-2); 2-nitro-p-phenylenediamine (5307-14-2); and 3-chloro-p-toluidine (95-74-9). ...

  48. TR-184: Nitrofen (CASRN 1836-75-5) 4.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr184.pdf

    ... All dosed and control rats were housed in a room with other rats receiving diets containing* 3-chloro-p-toluidine (95-74-9); 5-chloro- o-toluidine (95-74-4); 2-nitro-p-phenylenedia...

  49. TR-179: p-Quinone Dioxime (CASRN 105-11-3) 3.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr179.pdf

    ... hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); 2-nitro-p- phenylenediamine (5307-14-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-toluidine (95-74-9). ...

  50. TR-181: Michler's Ketone (CASRN 90-94-8) 3.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr181.pdf

    ... diamine hydrochloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethylthiourea (2489-77-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-toluidine (95-74-9). ...

 
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