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TR-174: p-Phenylenediamine Dihydrochloride (CASRN 624-18-0) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr174.pdf
Report Series No. 174 1979 BIOASSAY p-PHENYLENEDIAMINE DIHYDROCHLORIDE FOR POSSIBLE ... Report Series No. 174 1979 BIOASSAY p-PHENYLENEDIAMINE DIHYDROCHLORIDE FOR POSSIBLE ...
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TR-169: 2-Nitro-p-phenylenediamine (CASRN 5307-14-2) 3.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr169.pdf
No. 169 1979 BIOASSAY OF 2-NITRO-p-PHENYLENEDIAMINE FOR POSSIBLE CARCINOGENICITY CAS ... of Health BIOASSAY OF 2-NITRO-p-PHENYLENEDIAMINE FOR POSSIBLE CARCINOGENICITY ...
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TR-219: 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344... 4.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr219.pdf
BIOASSAY OF 2,6-DICHLORO-p-PHENYLENEDIAMINE (CAS NO. 609-20-1) IN F344 RATS AND ... BIOASSAY of 2,6-DICHLORO-p-PHENYLENEDIAMINE (CAS NO. 609-20-1) IN F344 RATS and ...
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TR-082: N-Phenyl-p-phenylenediamine (CASRN 101-54-2) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr082.pdf
2 BIOASSAY OF N-PHENYL-p-PHENYLENEDIAMINE FOR POSSIBLE CARCINOGENICITY CAS No. 101-54-2 ... of Health BIOASSAY OF N-PHENYL-p-PHENYLENEDIAMINE FOR POSSIBLE CARCINOGENICITY ...
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TR-113: 2-Chloro-p-phenylenediamine Sulfate (CASRN 61702-44-1... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr113.pdf
of Health BIOASSAY OF 2-CHLORO-p-PHENYLENEDIAMINE SULFATE FOR POSSIBLE ... REPORT ON THE BIOASSAY OF 2-CHLORO-p-PHENYLENEDIAMINE SULFATE FOR POSSIBLE ...
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p-Phenylenediamine dihydrochloride: Target Organs and Levels... 56KB
https://ntp.niehs.nih.gov/data/tr/100s/tr174levels
5 p-Phenylenediamine dihydrochloride: Target Organs and Levels of Evidence for TR-174 Bioassay of p-Phenylenediamine Dihydrochloride for Possible Carcinogenicity (CASRN 624-18-0) ...
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Abstract for TR-174 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr174
Abstract for TR-174 Bioassay of p-Phenylenediamine Dihydrochloride for Possible ... p-PDA HCl; p-OD HCl; p-phenylenediamine di-HCl; Durafur Black RC; Fourrine ...
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N-Phenyl-p-phenylenediamine: Target Organs and Levels of Evidence... 56KB
https://ntp.niehs.nih.gov/data/tr/000s/tr082levels
4 N-Phenyl-p-phenylenediamine: Target Organs and Levels of Evidence for TR-082 Bioassay of N-Phenyl-p-phenylenediamine for Possible Carcinogenicity (CASRN 101-54-2) Chemical (Study ...
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2-Chloro-p-phenylenediamine sulfate: Target Organs and Levels... 56KB
https://ntp.niehs.nih.gov/data/tr/100s/tr113levels
5 2-Chloro-p-phenylenediamine sulfate: Target Organs and Levels of Evidence for TR-113 Bioassay of 2-Chloro-p-phenylenediamine Sulfate for Possible Carcinogenicity (CASRN ...
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2-Nitro-p-phenylenediamine: Target Organs and Levels of Evidence... 57KB
https://ntp.niehs.nih.gov/data/tr/100s/tr169levels
9 2-Nitro-p-phenylenediamine: Target Organs and Levels of Evidence for TR-169 Bioassay of 2-Nitro-p-phenylenediamine for Possible Carcinogenicity (CASRN 5307-14-2) Chemical (Study ...
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2,6-Dichloro-p-phenylenediamine: Target Organs and Levels of... 57KB
https://ntp.niehs.nih.gov/data/tr/200s/tr219levels
8 2,6-Dichloro-p-phenylenediamine: Target Organs and Levels of Evidence for TR-219 Carcinogenesis Bioassay of 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344 Rats and ...
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Abstract for TR-82 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr082
Abstract for TR-82 Bioassay of N-Phenyl-p-phenylenediamine for Possible Carcinogenicity ... Full Report PDF Abstract N-phenyl-p-phenylenediamine is an industrial intermediate that is ...
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Abstract for TR-169 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr169
Abstract for TR-169 Bioassay of 2-Nitro-p-phenylenediamine for Possible Carcinogenicity ... Diaminonitrobenzene; m-Nitro-p-phenylenediamine; o-Nitro-p-phenylenediamine; ...
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Abstract for TR-113 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr113
Abstract for TR-113 Bioassay of 2-Chloro-p-phenylenediamine Sulfate for Possible ... sulfate; o-chloro-p-phenylenediamine sulfate; C.I. Oxidation Base 13A; ...
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Abstract for TR-219 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr219
Carcinogenesis Bioassay of 2,6-Dichloro-p-Phenylenediamine in F344 Rats andB6C3F1 ... A carcinogenesis bioassay of 2,6-dichloro-p-phenylenediamine, a chemicalintermediate, was ...
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RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
... the n-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD): (A) Standard Spectrum, (B) ... of n-(1,3-dimethylbutyl)-n'-phenyl-p-phenylenediamine (6PPD) is shown in Figure 8. ...
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RoC Profile: 2,4-Diaminotoluene; 15th RoC 2021 136KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diaminotoluene.pdf
... U.S. imports and exports of 2,4-diaminotoluene are reported as part of a category of similar compounds, including o-, m-, and p-phenylenediamine, di- aminotoluenes, and their ...
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TR-418: p-Nitroaniline (CASRN 100-01-6) in B6C3F1Mice (Gavage... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr418.pdf
... as the parent com- pound, 26% as p-phenylenediamine, and 43% as 2-amino-5-nitrophenol. ... The effect o f dimethylsulfoxide on the muta- genicity o f the hair dye p-phenylenediamine...
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Peer Review Report of the EpiSensA Skin Sensitization Assay ... 1.5MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-reinke-poster.pdf
... gallate 1A NA Cat.2 N N N Yes 3 P-Phenylenediamine 1A 1A Cat.1 P P P Yes 4 Methyl ... 11 Lactic acid N N N N N P N N P 12 P-Phenylenediamine P P P P P P P P P 13 Methyl heptane ...
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TR-187: 5-Chloro-o-toluidine (CASRN 95-79-4) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr187.pdf
... (95-74-9); 2-nitro-p-
phenylenediamine (5307-14-2); and nitrofen (1836-75-5). ... (106-47-8); N-phenyl-p-phenylenediamine hydrochloride (2198-59-6); ...
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Presentation: Introduction and Public Health Impact of Chemically... 1.3MB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/1-stokes.pdf
... Contact Dermatitis Group 2005-2006. Dermatitis 20: 149-160. 0 5 10 15 20 p-Phenylenediamine Methyldibromoglutaronitrile Formaldehyde Bacitracin Cobalt Neomycin Quaterium-15 ...
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Presentation: The Murine Local Lymph Node Assay: DA 1010KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf
... Methyl methacrylate Nickel (II) sulfate hexahydrate Phenyl benzoate p-Phenylenediamine Phthalic anhydride Potassium dichromate Propyl gallate Resorcinol Sodium lauryl ...
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Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB
https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf
... 2% 0.52 - 12.7% 03/23/12 H 2 O C 6 H 5 OH 94.11 solid Irritant 14 p-Phenyldiamine PPD 106-50-3 Sigma EtOH 1% 9.17 + 72.7% 03/08/12 EtOH, H 2 O C 6 H 8 N 2 108.14 solid Strong/...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... 0.05 0.74 80.0 108.16 106-50-3 P6001 N/A Toxic, irritant, diamine possible mutagen. ... by Spielmann et al. (1999). 12 p-Phenylenediamine Trichlorfon Cadmium Chloride ...
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ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf
... Aldehydes 0.083 (18.0) 0.118 (6.5) p-Phenylenediamine 5 Intermediate in chemical ... (1, 1) AOO 3.79 52.30 p-Phenylenediamine (1, 3) AOO 5.14 23.30, 37.40, 75.30 ...
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TR-351: para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in... 12.2MB
https://ntp.niehs.nih.gov/go/tr351
... considered equivocal. 2- Chloro-p-phenylenediamine sulfate (NCI, 1978b) and ...-Chloro-o-nitroaniline 89-63-4 N H 2 2-Chloro-p-phenylenediamine 61702-44-1 q sulfate Cl . ...
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TR-084: 2,4-Diaminoanisole Sulfate (CASRN 615-05-4) 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr084.pdf
... Imines, produced within the hair shaft by the oxidation of _ The CAS registry number is 615-05-4. 1 a primary intermediate, such as p-phenylenediamine, react with 2,4- ...
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TR-145: 3-Chloro-p-Toluidine (CASRN 95-74-9) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr145.pdf
... diets containing ^\ 2-nitro-p-phenylenediamine (5307-14-2); 5-chloro-o-toluidine ... receiving diets containing 2-nitro-p-phenylenediamine (5307-14-2); Michler's ketone ...
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TR-168: N-(1-Naphthyl)ethylenediamine Dihydrochloride (CASRN... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr168.pdf
... (2243-62-1); 2-chloro-p-phenylenediamine sulfate (61702-44-1); aniline ... pyUphosphate (126-72-7) ; 2-chloro-p-phenylenediamine sulfate (61702- 44-1); and aniline ...
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TR-179: p-Quinone Dioxime (CASRN 105-11-3) 3.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr179.pdf
... (95-79-4); N-phenyl-p-phenylenediamine hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); 2-nitro-p-
phenylenediamine (5307-14-2); dibutyltin diacetate ...
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TR-183: Dibutyltin Diacetate (CASRN 1067-33-0) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr183.pdf
... (95-79-4); N-phenyl-p-phenylenediamine hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethyl- thiourea (2489-77-2); 2-nitro-p-phenylenediamine (5307-14-2); and ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... TR-219 10/15/80 2,6-Dichloro-p- phenylenediamine 609-20-1 N No Evidence N No ... N No Evidence TR-174 10/25/78 p-Phenylenediamine dihydrochloride 624-18-0 N No ...
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TR-089: o-Anisidine Hydrochloride (CASRN 134-29-2) 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr089.pdf
... Rats (CAS 615-66-7) 2-chloro-p-phenylenediamine sulfate (CAS 20265-97-8) ... Mice (CAS 615-66-7) 2-chloro-p-phenylenediamine sulfate (CAS 126-72-7) tris ...
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TR-130: Aniline Hydrochloride (CASRN 142-04-1) 3.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr130.pdf
... (1465-25-4); 2-chloro-p-phenylenediamine sulfate (61702-44-1); and ... dihydrochloride (1465-25-4); and 2-chloro-p-phenylenediamine sulfate (61702-44-1). ...
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TR-186: 4,4'-Methylenebis-(N,N-dimethyl)benzeneamine (CASRN 101... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr186.pdf
... ketone (90-94-8); 2-nitro-p-
phenylenediamine (5307-14-2); p-chloroaniline (106-47-8); 5-chloro- o-toluidine (95-79-4); N-phenyl-p-phenylenediamine hydrochloride (2198-59-6); ...
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TR-189: p-Chloroaniline (CASRN 106-47-8) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr189.pdf
... (95-74-9); 1-phenyl-2-thiourea (103-85-5); dibuty1tin diacetate (1067-33-0); N-phenyl-p-phenylenediamine hydrochloride (2198-59-6); and 2-nitro-p-phenylenediamine (5307-14-2). ...
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RoC Background Document for 4,4'-Thiodianiline; March 27, 2002 1.1MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/tdapub_no_appendices_508.pdf
... 4,4'-diaminodiphenyl sulfide, bis(p-aminophenyl)sulfide, bis(4-aminophenyl)sulfide thioaniline, and thiodi-p-phenylenediamine. Its RTECS number is BY9625000 (ChemFinder 2001). ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Bioassay of 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344 Rats and ... TR-174 PDF (3.25 MB) Bioassay of p-Phenylenediamine Dihydrochloride for Possible ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Bioassay of 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344 Rats and ... TR-174 PDF (3.25 MB) Bioassay of p-Phenylenediamine Dihydrochloride for Possible ...
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TR-094: 4-Amino-2-nitrophenol (CASRN 119-34-6) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr094.pdf
... administered one of the following chemicals: Rats Feed Studies (CAS 624-18-0) p-phenylenediamine dihydrochloride (CAS 18662-53-8) nitrilotriacetic acid, trisodium salt (CAS ...
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TR-095: 3-(Chloromethyl) pyridine Hydrochloride (CASRN 6959-48... 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr095.pdf
... 140-49-8) 4-chloroacetylacetanilide (CAS 139-94-6) nithiazide (CAS 624-18-0) p-phenylenediamine dihydrochloride (CAS 99-56-9) 4-nitro-o-phenylenediamine (CAS 89-25-8) ...
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TR-109: 4-Nitroanthranilic Acid (CASRN 619-17-0) 4.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr109.pdf
...aphthyl)ethylenediamine dihydrochloride (1465-25-4); 2-chloro-p-phenylenediamine sulfate (61702-44-1); aniline hydrochloride (142-04-1); and p-anisidine hydrochloride (20265-97-8). ...
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TR-129: Trimethylthiourea (CASRN 2489-77-2) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr129.pdf
... dibutyltin diacetate (1067-33-0); 2-nitro-p-phenylenediamine (5307-14-2); p-chloroaniline (106-47-8); 5-chloro-o-toluidine (95-79-4); and p-aminodiphenylamine (2198-59-6). ...
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TR-140: Pivalolactone (CASRN 1955-45-9) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr140.pdf
... (54150-69-5); 4 f -(chloroacetyl)-acetanilide (140-49-8); nithiazide (139-94-6); p-phenylenediamine dihydrochloride (624-18-0); 4-nitro- o-phenylenediamine (99-56-9); ...
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TR-148: 1-Phenyl-2-thiourea (CASRN 103-85-5) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr148.pdf
... (1067- 33-0); 2-nitro-p-phenylenediamine (5307-14-2); 3-chloro-p-toluidine (95-74-9); 5-chloro-o-toluidine (95-79-4); and N-phenyl-p-phenylene- diamine hydrochloride (2198-59-6). ...
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TR-178: 2-(Chloromethyl)pyridine Hydrochloride (CASRN 6959-47... 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr178.pdf
... hydrochloride (54150- 69-5); 4'-(chloroacetyl)-acetanilide (140-49-8); p-phenylenediamine dihydrochloride (624-18-0); 4-nitro-o-phenylenediamine (99-56-9); and ...
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TR-184: Nitrofen (CASRN 1836-75-5) 4.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr184.pdf
... 3-chloro-p-toluidine (95-74-9); 5-chloro- o-toluidine (95-74-4); 2-nitro-p-phenylenediamine (5307-14-2); ami- trole (61-82-5); l-phenyl-2-thiourea (103-85-5); dibutyltin ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... Bioassay of 2,6-Dichloro-p-Phenylenediamine (CASRN 609-20-1) in F344 Rats and ... TR-174 PDF (3.25 MB) Bioassay of p-Phenylenediamine Dihydrochloride for Possible ...
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TR-092: Hydrazobenzene (CASRN 122-66-7) 4.2MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr092.pdf
... tris(2,3-dibromopropyl) phosphate (126-72-7); N-(l-naphthyl)ethylenediamine dihydrochloride (1465-25-4); 2-chloro-p-phenylenediamine sulfate (61702-44-1); and acetone (67-64-1). ...
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TR-076: Tris (2,3-Dibromopropyl) Phosphate (CASRN 126-72-7) 4.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr076.pdf
... All rats used in this study were housed in a room with other * rats receiving diets containing 2-chloro-p-phenylenediamine sulfate * CAS registry numbers are given in parentheses. ...