-
Abstract for TER92020 60KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter92020
Abstract for TER92020 Developmental Toxicity Studies of Ethylenediamine in New Zealand White Rabbits CASRN: 107-15-3 Chemical Formula: C2H8N2 Molecular Weight: 60.0992 Report Date: ...
-
TR-168: N-(1-Naphthyl)ethylenediamine Dihydrochloride (CASRN... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr168.pdf
168 1979 BIOASSAY OF N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE FOR POSSIBLE ... of Health BIOASSAY OF N-(1-NAPHTHYL)ETHYLENEDIAMINE DIHYDROCHLORIDE FOR POSSIBLE ...
-
Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... containing, in any concentration, ethylenediamine, diethylenetriamine, and diglycidyl ... Epoxy resins systems containing, in any concentration, ethylenediamine, ...
-
TR-011: Trisodium Ethylenediaminetetraacetate Trihydrate (EDTA... 2.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr011.pdf
... Bethesda, Maryland. iv SUMMARY A bioassay of the chelating agent, trisodium ethylenediamine- tetraacetate trihydrate (Na3EDTA-3H20), for possible carcinogenicity was ...
-
Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
... An example of this potential problem is with ethylenediamine (free base) in Table 3 of ... Ethylenediamine would have been classified as nonsensitizing if concentrations of 0.1 to ...
-
Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf
... Workers were exposed to a mixture of DMAE, ethylenediamine, propylene oxide, and ... exposed to a mixture of DMAE, ethylenediamine, propylene oxide, and ...
-
Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf
... 5392-40-5 N N/A 1B 1 1A EGDMA 97-90-5 Y N/A 1B 1 1B Ethylene diamine (free base) 107-15-3 N N/A 1B 1 1B Glycerol 56-81-5 N N/A NC NC NC 4-Hydroxybenzoic acid 99-96-7 N N/A NC ...
-
TOX-46: Hepathe Liver Carcinogen Methapyrilene Hydrochloride... 1.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox046.pdf
... Hydrochloride, NTP TOX 46 ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION Methapyrilene hydrochloride is in the ethylenediamine class of histamine H 1 -receptor antagonists. ...
-
TOX-67: 2-Methylimidazole and 4-Methylimidazole 5.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox067.pdf
... HUMAN EXPOSURE 2-Methylimidazole is produced by cyclocondensation of aldehyde and ammonia with methylglyoxal or by platinum/alumina cyclization of ethylenediamine with acetic acid. ...
-
TR-054: 2,4-Dinitrotoluene (CASRN 121-14-2) 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr054.pdf
... acid (619-17-0); 1,5-naphthalenediamine (2243-62-1); N-(l-naphthyl) ethylenediamine dihydrochloride (1465-25-4); 2-chloro-p-phenylenedia- mine sulfate (61702-44-1); ...
-
TR-076: Tris (2,3-Dibromopropyl) Phosphate (CASRN 126-72-7) 4.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr076.pdf
... All mice used in this study were housed with other mice receiving diets containing o-anisidine hydrochloride (134-29-0); N-(l-naphthyl) ethylenediamine dihydrochloride ...
-
TR-116: p-Anisidine Hydrochloride (CASRN 20265-97-8) 3.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr116.pdf
... (2243-62-1); N-(l-naphthyl) ethylenediamine dihydrochloride (1465-25-4); 2-chloro- p-phenylenediamine sulfate (61702-44-1); and aniline hydrochloride (142-04-1). ...
-
TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 9.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr516.pdf
... is produced by cyclocondensation of aldehyde and ammonia with methylglyoxal or by plat- inum/alumina cyclization of ethylenediamine with acetic acid (Lewis, 1996). ...
-
TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf
... by the reaction "encapsulated" in a matrix of compatible elastomers. of ethylenediamine with carbon disulfide in aqueous ETU is moderately soluble in methanol, ethanol, alcohol. ...
-
TR-315: Oxytetracycline Hydrochloride (CASRN 2058-46-0) in F344... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr315.pdf
... sprayed with 0.1 M aqueous disodium ethylenediamine tetraacetic acid and air dried over- ... sprayed with 0.1M aqueous diso- dium ethylenediamine tetraacetic acid and air dried ...
-
NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... N No Evidence N No Evidence P Clear Evidence TR-168 08/31/78 N-(1-naphthyl) ethylenediamine dihydrochloride 1465-25-4 N No Evidence N No Evidence N No Evidence N No Evidence ...
-
ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... EGDMA 97-90-5 198.22 1.38 Liquid Carboxylic Acids Gerberick Ethylenediamine free base - 107-15-3 60.10 0.19 Liquid Amines Gerberick Ethylhexyl acrylate Octyl acrylate; 2- ...
-
Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... NA NA 126.9 0.51 248.74 0.51 24 Ethylenediamine-tetraacetic acid 60-00-4 2.92 0.01 NA ... NA NA 4.0 0.012 333.33 0.012 24 Ethylenediamine-tetraacetic acid 60-00-4 2.92 0.01 NA ...
-
ICCVAM Report: Corrositex: An In Vitro Method for Assessing Dermal... 5.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf
... salt inorganic base + + - diethylamine amine + + - diethylenetriamine amine + + - ethylenediamine amine + + - cyclohexylamine amine + + - potassium hydroxide inorganic base ...
-
Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... This regulation eliminates the need to establish a maximum permissible level for residues of (S,S)-ethylenediamine disuccinic acid trisodium salt. NTP Information Cited National ...
-
Draft TR-601: Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered... 3.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr601_508.pdf
... K. Genotoxicity evaluation of benzene, di(2-ethylhexyl) phthalate, and 28 trisodium ethylenediamine tetraacetic acid monohydrate using a combined rat 29 comet/micronucleus assays. ...
-
TR-601: Di(2-ethylhexyl) Phthalate Administered in Feed to Sprague... 4.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr601_508.pdf
... Saito K. Genotoxicity evaluation of benzene, di(2-ethylhexyl) phthalate, and trisodium ethylenediamine tetraacetic acid monohydrate using a combined rat comet/micronucleus assays. ...
-
Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
... glycol dimethyl ether. 721.3560 Derivative of tetrachloroethylene. 721.3565 Ethylenediamine, substituted, so- dium salt. 721.3620 Fatty acid amine condensate, polycarboxylic ...
