-
Abstract for TER92116 60KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter92116
Abstract for TER92116 Developmental Toxicity of Glyoxal Trimeric Dihydrate in ... This study was conducted to assess the potential for orally administered glyoxal trimeric ...
-
Abstract for TER92121 61KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter92121
Abstract for TER92121 Developmental Toxicity of Glyoxal Trimeric Dihydrate, in New Zealand ... This study was conducted to assess the potential for orally administered glyoxal trimeric ...
-
Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB
https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf
... H 2 O 100% 0.86 - 102.1% 03/23/12 H 2 O C 3 H 8 O 3 92.09 liquid Non-toxin 8 Glyoxal GLO 107-22-2 Sigma H 2 O 0.5% 5.68 + 23.0% 03/23/12 H 2 O OHCCHO 58.04 liquid Moderate 9 Lactic ...
-
Peer Review Report of the EpiSensA Skin Sensitization Assay ... 1.5MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-reinke-poster.pdf
... heptane carbonate 1A - Cat.2 P P P Yes 5 Glyoxal 40% solution in water 1A 1A Cat.2 P P P ... Exp. 1 Exp. 2 Exp. 3 Exp. 1 Exp. 2 Exp. 3 Exp. 1 Exp. 2 Exp. 3 1 Glyoxal 40% solution in ...
-
RoC Background Document: Chloroprene; Oct. 30-31, 1997 5.9MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/chloroprene1_508be.pdf
... Formaldehyde, 1-chloroacrolein, glyoxal, chloroglyoxal, and chlorohydroxy acids or ... may form formaldehyde, 1-chloroacrolein, glyoxal, chloroglyoxal, and chloro- hydroxy acids ...
-
Nomination Background: 2,3-Butanedione (CASRN: 431-03-8) 1.8MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/artificial_butter_flavoring_508be.pdf
... Butadiene Butanedione Diacetyl (natural) Dimethyl diketone Dimethyl glyoxal Dimethylglyoxal Glyoxal, dimethyl- NSC 8750 Source(s): ChemIDplus, 2004a; Registry (1984) PubChem ...
-
CERHR Monograph: Potential Human Reproductive and Developmental... 4.3MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/ethylene/eg_monograph.pdf
... Glycol Alcohol Dehydrogenase * Glycolaldehyde Aldehyde Dehydrogenase Glycolic Acid Glyoxal ... Further oxidation of glycoaldehyde to glyoxal was catalyzed with a V max of 3.2 nmol/min/...
-
TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf
... terephthalate (PET) solid-state resins, glyoxal, safety explosives, plasticizers, and ... It is also used in the manufacture of polyester fibers, glyoxal, resins, and other ...
-
Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
... References Comment Glyoxal// Oxaldehyde// Ethanedial// Biformyl 107-22-2 aldehyde biocides, antimicrobial// in textiles, organic synthesis, glues + + + Basketter et al. (1994); ...
-
Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... 0.12 2 0.02 1.50 0.08 2 + + Glyoxal 1.40 0.60 NA + trans-2-Hexenal 5.50 2.60 ... 250 a 325 Cobalt sulfate 313 b 50 Glyoxal b 345 150 Diethylenetriamine b 411 463 ...
-
RoC Background Document: Ultraviolet (UV) Radiation, Broad Spectrum... 3.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/uv_no_appendices_508.pdf
... mutagen, glyoxal, was produced by exposure of DNA to an oxygen-radical- forming system (5 mM ferrous sulfate-ethylenediaminetetraacetic acid, +37 o C, 60 min). Glyoxal was ...
-
TR-467: Chloroprene (CASRN 126-99-8) in F344/N Rats and B6C3F1Mice... 14.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr467.pdf
... Reaction of chloroprene with hydroxyl radicals or ozone may form formaldehyde, 1-chloroacrolein, glyoxal, chloroglyoxal, and chlorohydroxy acids or other aldehydes. 18 Chloroprene, ...
-
RoC Background Document: Ethyl Acrylate; Dec. 2-3, 1998 834KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/ethylacryl_noapps_508.pdf
... Environ.Mol.Mutagen. 19 Suppl 21:2-141. 68. Zimmermann, F.K., and A. Mohr. 1992. Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl ...
-
TR-593: NTP Technical Report on the Toxicology and Carcinogenesis... 7.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr593_508.pdf
... The related 1,2-dicarbonyl compounds, methylglyoxal and glyoxal, also form adducts with ... initiating and promoting activities of diacetyl and glyoxal in rat stomach mucosa. ...
-
CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf
... In addition, D, L-lactaldehydes are oxidized to methyl glyoxal with loss of the chirality center, which glyoxylase with GSH as co-substrate converts stereospecifically to ...
-
ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... with 1,2,3-propanetriol 30618-84-9 166.19 -1.29 - Lipids CESIO Glyoxal Oxaldehyde; Ethanedial; Biformyl 107-22-2 58.04 0.19 Liquid Aldehydes Gerberick Hexane - 110-54-3 ...
-
TR-284: Diallylphthalate (CASRN 131-17-9) in F344/N Rats (Gavage... 8.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr284.pdf
... Biol. Chem. 44:3017-3018. 100. Yamaguchi, T. (1982) Mutagenicity of trioses and methyl glyoxal on Salmonella typhi- murium. Agric. Biol. Chem. 46:849-851. Diallylphthalate,NTP TR ...
-
TR-396: Monochloroacetic Acid (CASRN 79-11-8) in F344/N Rats... 14.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr396.pdf
... J. Ind Hx.Toxicol. 23, 78-82. Yamaguchi, T., and Nakagawa, K. (1983). Mutagenicity of and formation of oxygen radicals by trioses and glyoxal derivatives. A@. BioL Chem. 47, ...
-
TR-544: Dibromoacetonitrile (CASRN 3252-43-5) in F344/N Rats... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr544.pdf
... Mol. Mutagen. 19 (Suppl. 21), 2-141. Zimmerman, F.K., and Mohr, A. (1992). Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl acrylate, ...
-
Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf
... arabinoside; methyl-GAG = methyl-glyoxal bis guanyl hydrazine; IT = intrathecal; ... APL = acute promyelocytic leukemia; methyl-GAG = methyl-glyoxal bis guanyl hydrazone. ...
