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Search suggestions for "108-46-3".

  1. CEBS Data Related to Resorcinol (108-46-3) https://cebs.niehs.nih.gov/cebs/test_article/108-46-3
  2. Report on Carcinogens Diglycidyl resorcinol ether (DGRE) https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/diglycidylresorcinolether.pdf


162 results found for "108-46-3".

  1. TR-403: Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1Mice... 15.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr403.pdf

    3 ~,&,~ 5t~'vl~-~'v~ "%~.,.~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF RESORCINOL (CAS NO. 108-46-3) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND ...

  2. TR-257: Diglycidyl Resorcinol Ether (Technical Grade) (CASRN... 10.0MB

    https://ntp.niehs.nih.gov/go/tr257

    CARCINOGENESIS STUDIES OF DIGLYCIDYL RESORCINOL ETHER (TECHNICAL GRADE) (CAS NO. 101-90-6) ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF DIGLYCIDYL RESORCINOL ETHER (TECHNICAL GRADE) ...

  3. RoC Profile: Diglycidyl Resorcinol Ether; 15th RoC 2021 116KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diglycidylresorcinolether.pdf

    Diglycidyl Resorcinol Ether CAS No. 101-90-6 Reasonably anticipated to be a human ... O C H 2 O O C H 2 O Carcinogenicity Diglycidyl resorcinol ether is reasonably anticipated ...

  4. Abstract for TR-403 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr403

    Abstract for TR-403 Toxicology and Carcinogenesis Studies of Resorcinol in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 108-46-3 Chemical Formula: C6H6O2 Molecular Weight: ...

  5. Abstract for TR-257 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr257

    Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) in ... Full Report PDF Abstract Diglycidyl resorcinol ether (DGRE), a pale, yellow, translucent, ...

  6. Target Organs and Levels of Evidence for TR-403 56KB

    https://ntp.niehs.nih.gov/data/tr/400s/tr403levels

    Target Organs and Levels of Evidence for TR-403 Toxicology and Carcinogenesis Studies of Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1 Mice (Gavage Studies) Chemical (Study ...

  7. Target Organs and Levels of Evidence for TR-257 59KB

    https://ntp.niehs.nih.gov/data/tr/200s/tr257levels

    Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) ... Levels Study Laboratory Diglycidyl resorcinol ether (DGRE) 101-90-6 02/28/1983 Gavage ...

  8. TR-330: 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr330.pdf

    ... 4-hexyl- 0,62.5,or 125mgkg 4-hexyl- 0,62.5, or 125m g k g 4-hexyl- resorcinol in corn oil 5 d/wk resorcinol in corn oil 5 d/wk resorcinol in corn oil 5 d/wk resorcinol in corn ...

  9. ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf

    ... Metals 4.800 (3.1) 2.606 (11.8) Resorcinol 5 Cosmetics; Manufacturing; Personal ... 23.20, 23.60, 24.40, 29.80, 31.00 Resorcinol (1, 2) AOO 4.33 10.40, 12.50 ...

  10. Stomach, Forestomach, Epithelium - Degeneration - Nonneoplastic... 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-forestomach/Epithelium-Degeneration

    ... National Toxicology Program. 1986. NTP TR-257. Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) (CAS No. 101-90-6) in F344/N Rats and B6C3F1 ...

  11. Stomach, Forestomach, Epithelium - Degeneration 260KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/forestomach/epdegen/stomach-forestomach-epithelium-degeneration-pdf_508.pdf

    ... Mosby, St Louis, MO, 3-62. National Toxicology Program. 1986. NTP TR-257. Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) (CAS No. 101-90-6) ...

  12. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... and its Dihydrochloride 101-80-4 see 4,4'-Oxydianiline 101-90-6 see Diglycidyl Resorcinol Ether 106-46-7 see 1,4-Dichlorobenzene 106-87-6 see 4-Vinyl-1-cyclohexene Diepoxide ...

  13. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... Diesel Exhaust Particulates Di(2-ethylhexyl) Phthalate Diethyl Sulfate Diglycidyl Resorcinol Ether 3,3'-Dimethoxybenzidine (see 3,3'-Dimethoxybenzidine and Dyes Metabolized to ...

  14. TOX-70: p-tert-Butylcatechol (CASRN 98-29-3) 4.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox070.pdf

    ... p-methylcatechol, hydroquinone, and resorcinol induced a less pronounced degree of ... No lesions were observed in control rats. The carcinogenicity of hydroquinone, resorcinol, ...

  15. Minutes: BSC TRRS; March 11, 1991 723KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1991/mar/trrs11mar1991mins_508.pdf

    Long-Term S t u d i e s 6459-94-5 Water 6471-49-4 Feed 137-09-7 Gavage 110-00-9 Gavage 91-20-3 I n h a l a t i o n 117-39-5 Feed 108-46-3 Gavage Short-Term T o x i c i t y S t u d ...

  16. Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf

    .../Severe EtOH 0.5% 10.60 + 97.7% 04/19/12 EtOH 1% 136.90 + 59.0% 04/19/12 15 Resorcinol RES 108-46-3 Sigma-Aldrich H 2 O 2% 3.25 + 22.7% 03/23/12 H 2 O C 6 H 6 O 2 110.11 solid ...

  17. TR-574: Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1... 13.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr574_508.pdf

    ... 2-O-methylpyrogallol, and traces of resorcinol were detected in the urine 24 hours ... Pyrogallol was metabolized to resorcinol by albino rat fecal extract in vitro. This ...

  18. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... while resorcinol and rotenone were negative. p -Anisidine and 8-hydroxyquinoline were negative in the Tg.AC while all four were negative in p53 def . However, resorcinol induced ...

  19. Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf

    ... bromide 100-11-8 N N/A 1A 1 1A Propyl gallate 121-79-9 Y N/A 1A 1 1A Resorcinol 108-46-3 N N/A 1B NC 1B Salicylic acid 69-72-7 N N/A 1B NC NC Vanillin 121-33-5 N N/A NC ...

  20. Presentation: The Murine Local Lymph Node Assay: DA 1010KB

    https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf

    ... benzoate p-Phenylenediamine Phthalic anhydride Potassium dichromate Propyl gallate Resorcinol Sodium lauryl sulfate Trimellitic anhydride 1-Bromobutane Chlorobenzene Diethyl ...

  21. TR-126: 2,5-Toluenediamine Sulfate (CASRN 6369-59-1) 3.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr126.pdf

    ... When applied to the scalp of human volunteers in conjunction with detergents, resorcinol and hydrogen peroxide, the diacetyl derivative was excreted in the urine for two days ...

  22. Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf

    ... dichromate 0.33 0.09 2 0.20 2 + + Resorcinol 5.92 3 NC NA 5 6 - Salicylic acid NC .../incidence data were not reported, resorcinol has been reported to be a nonsensitizer ...

  23. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence NE No Evidence NE No Evidence P Clear Evidence TR-403 03/11/91 Resorcinol 108-46-3 NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-402 03/11/91 ...

  24. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ...oxymethylene)]bisoxirane see Diglycidyl Resorcinol Ether phenyloxirane see ... see Ceramic Fibers (Respirable Size) resorcinol diglycidyl ether see Diglycidyl ...

  25. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ...oxymethylene)]bisoxirane see Diglycidyl Resorcinol Ether phenyloxirane see ... see Ceramic Fibers (Respirable Size) resorcinol diglycidyl ether see Diglycidyl ...

  26. TR-350: Tribromomethane (Bromoform) (CASRN 75-25-2) in F344/N... 11.8MB

    https://ntp.niehs.nih.gov/go/tr350

    ... Incidence at EGQG Mason Research Institute Diglycidyl resorcinol ether 0150 1/50 1/50 Diglycidyl resorcinol ether 1/50 (b)2/50 (bt 3/50 1,2-Dichloropropane 0150 (b)2/50 ...

  27. TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf

    ... (Telone 11) 269 Diglycidyl resorcinol ether (DGRE) 257 Dimethylhydrogenphosph... Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (CAS No. 101-90-6) in ...

  28. TR-321: Bromodichloromethane (CASRN 75-27-4) in F344/N Rats and... 10.6MB

    https://ntp.niehs.nih.gov/go/tr321

    ... the diglycidyl resorcinol ether study Bromodichloromethane, NTP TR 321 90 TABLE A4c. ... Mason Research Institute Diglycidyl resorcinol ether Diglycidyl resorcinol ether ...

  29. TR-524: Photocarcinogenesis Study of Glycolic Acid and Salicylic... 17.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr524.pdf

    ... development of peels starting in the 1880s, with the topical use of salicylic acid, resorcinol, phenol, and trichloroacetic acid, and their use in the early 1900s in facial salons. ...

  30. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-403 PDF (15.05 MB) Toxicology and Carcinogenesis Studies of Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1 Mice (Gavage Studies) 1992 Technical Report TR-402 ...

  31. TR-376: Allyl Glycidyl Ether (CASRN 106-92-3) in Osborne-Mendel... 14.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr376.pdf

    ... Two of these related compounds, glycidol (NTP, 1990) and diglycidyl resorcinol ether (NTP, ... of Di- glycidyl Resorcinol E ther (Technical Grade) in F344/N Rats and B6C3F1 Mice. ...

  32. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    ... Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether in F344/N Rats and ... Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether in F344/N Rats and ...

  33. Minutes: BSC TRRS; Feb 28, 1983 601KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1983/feb/83feb28trrsmins_508.pdf

    ... Diglycidyl Resorcinol Ether. Dr. Holland was a principal reviewer f o r the report on the ... Holland moved that the technical report on the bioassay of diglycidyl resorcinol ether be ...

  34. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-403 PDF (15.05 MB) Toxicology and Carcinogenesis Studies of Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1 Mice (Gavage Studies) 1992 Technical Report TR-402 ...

  35. ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf

    ... vehicle to assess its usefulness Basketter et al., 2007 1 Original research that re-evaluated resorcinol in the local lymph node assay, which identified resorcinol as a sensitizer. ...

  36. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-403 PDF (15.05 MB) Toxicology and Carcinogenesis Studies of Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1 Mice (Gavage Studies) 1992 Long-Term Carcinogenicity ...

  37. TR-263: 1,2-Dichloropropane (Propylene Dichloride) (CASRN 78... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr263.pdf

    ... (16%) 5/50 (10%) 13/50 (26%) Diglycidyl Resorcinol Ether 7/49 (14%) 7/49 (14%) 13/49 (26%) ... Oo/r) 2!50 (4%) 7. 50 ( 14%) Diglycidyl Resorcinol Ether 3i48 (60() 0 48 (Oo/r) 3/48 (6o/...

  38. TR-367: Phenylbutazone (CASRN 50-33-9) in F344/N Rats and B6C3F1Mice... 10.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr367.pdf

    ... Historical Incidence at EG&G Mason Research Institute Diglycidyl resorcinol ether Diglycidyl resorcinol ether 1 ,2-Dichloropropane Chlorodibromomethane n-Butyl chloride ...

  39. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... Resorcinol// 1,3- Dihydroxybenzene 108-46-3 phenolic pharmaceutical (acne treatment, antipruritic, antiseptic, eye drops)// cosmetics// hair dyes// tanning// resins - - - + ...

  40. TR-339: 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr339.pdf

    ... In the 4-hexyl- resorcinol study, these neoplasms were present in 10 vehicle control male ... 0/50 0/50 0/50 4-Hexy !resorcinol 0/49 0/49 0/49 2-Mercaptobenzothiazole ...

  41. TR-366: Hydroquinone (CASRN 123-31-9) in F344/N Rats and B6C3F1Mice... 14.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr366.pdf

    ... by dilution of aliquots with an aqueous resorcinol solution (an internal standard), ... XXI. The fates of quinol and resorcinol in the rabbit. Biochem. J. 44:234. 81 ...

  42. TR-408: Mercuric Chloride (CASRN 7487-94-7) in F344 Rats and... 12.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr408.pdf

    ... Research and Development Corporation Resorcinol Overall Historical Incidence Total ... Research and Development Corporation Resorcinol 0150 0150 0150 Overall Historical ...

  43. TR-597: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered... 3.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr597_508.pdf

    ... Use, and Human Exposure 2H4MBP is synthesized by condensation of benzoic acid with resorcinol monomethyl ether in the presence of heat, zinc chloride, and polyphosphoric acid or ...

  44. TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf

    ... Lasting 8 to 13 Months Study Diglycidyl resorcinol ether 1,2-Dichloropropane Butyl benzyl ... Lasting 8 to 13 Months Study Diglycidyl resorcinol ether 1,2-Dichloropropane Benzyl ...

  45. TR-495: Sodium Nitrite (CASRN 7632-00-0) IN F344/N Rats and B6C3F1Mice... 16.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr495.pdf

    ... sodium acetate) and a color reagent (hydrochloric acid, resorcinol and zinconyl chloride). ... sodium acetate) and a color reagent (hydrochloric acid, resorcinol and zinconyl chloride). ...

  46. TR-361: Hexachloroethane (CASRN 67-72-1) in F344/N Rats (Gavage... 7.2MB

    https://ntp.niehs.nih.gov/go/tr361

    ... Historical Incidence a t EG%G Mason Research Institute Diglycidyl resorcinol ether (b) 1150 Diglycidyl resorcinol ether 0150 I .a-Dichloropropane 0/50 Chlorodibromomethane 0150 ...

  47. Draft DART-05: Modified One-Generation Study of 2-Hydroxy-4-methoxyben... 3.3MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/dart05_508.pdf

    ... and Human Exposure 11 2H4MBP is synthesized by condensation of benzoic acid with resorcinol monomethyl ether in 12 the presence of heat, zinc chloride, and polyphosphoric acid ...

  48. DART-05: Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophen... 6.0MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart05_508.pdf

    ... Use, and Human Exposure 2H4MBP is synthesized by condensation of benzoic acid with resorcinol monomethyl ether in the presence of heat, zinc chloride, and polyphosphoric acid or ...

  49. TR-312: n-Butyl Chloride (CASRN 109-69-3) in F344/N Rats and... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr312.pdf

    ... Adenoma or Carcinoma in Vehicle Controls Historical Incidence at EG&G Mason Research Institute Diglycidyl resorcinol ether Diglycidyl resorcinol ether 1,2-Dichloropropane ...

  50. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... 45 Chloramphenicol 0.79 10.5 3393.1 245 Resorcinol 0.8 2.73 300.6 246 37 Barium II nitrate ... sulfate * 5 H2O 0.33 1.2 299.6 245 Resorcinol 0.8 2.73 300.6 279 Thioacetamide 4.17 ...

 
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