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Search suggestions for "108-78-1".

  1. CEBS Data Related to Melamine (108-78-1) https://cebs.niehs.nih.gov/cebs/test_article/108-78-1


147 results found for "108-78-1".

  1. TR-245: Melamine (CASRN 108-78-1) in F344/N Rats and B6C3F1Mice... 8.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr245.pdf

    5 CARCINOGENESIS BIOASSAY OF MELAMINE (CAS NO. 108-78-1) IN F344/N RATS AND B6C3F1 MICE (FEED STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National ...

  2. Melamine: Target Organs and Levels of Evidence for TR-245 57KB

    https://ntp.niehs.nih.gov/data/tr/200s/tr245levels

    4 Melamine: Target Organs and Levels of Evidence for TR-245 Carcinogenesis Bioassay of Melamine (CASRN 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) Chemical (Study Title) ...

  3. Abstract for TR-245 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr245

    5abs Abstract for TR-245 Carcinogenesis Bioassay of Melamine in F344/N Rats and B6C3F1 Mice (Feed Study) CASRN: 108-78-1 Chemical Formula: C3H6N6 Molecular Weight: 126.13 Synonyms/...

  4. Minutes: BSC; June 12, 2008 280KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2008/june/minutes20080612.pdf

    ......... 31 Melamine and Cyanuric acid ......contaminants and dietary supplements; melamine and cyanuric acid and furan, food ...

  5. Final RoC Background Document for Formaldehyde 5.8MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2009/november/formaldehyde_bd_final.pdf

    ... phenol-formaldehyde, polyacetal, and melamine- formaldehyde resins) that are used to ... mEH: microsomal epoxide hydrolase MF: melamine-formaldehyde mg: milligram, 10 -3 gram ...

  6. Abstract for TR-163 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr163

    Calcium cyanamide can be dimerized to dicyandiamide, an intermediate for melamine, one of the basic ingredients in amino plastics and resins. Other products prepared from calcium ...

  7. SOT Annual Meeting: NIEHS and NTP Activitie; March 7-11, 2010 281KB

    https://ntp.niehs.nih.gov/ntp/pressctr/mtgs_wkshps/sot_49_activities.pdf

    ... Center) Roundtable Melamine Contamination of Infant Formulas: Lessons Learned 12:30-12:45 PM Dose-Response and Risk Assessment Considerations of Melamine in Infants Christopher ...

  8. Kidney - Nephropathy, Obstructive - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/kidney/NephropathyObstructive

    Hard GC, Flake GP, Sills RC. 2009. Re-evaluation of kidney histopathology from 13-week toxicology and two-year carcinogenicity studies of melamine in the F344 rat: Morphologic ...

  9. Kidney - Nephropathy, Obstructive 864KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/urinary/kidney/neobs/kidney-nephropathy-obstructive-pdf_508.pdf

    ... Re-evaluation of kidney histopathology from 13-week toxicology and two-year carcinogenicity studies of melamine in the F344 rat: Morphologic evidence of retrograde nephropathy. ...

  10. Presentation: Predicting Acute Toxicity Hazard in the Absence... 1.9MB

    https://ntp.niehs.nih.gov/iccvam/meetings/at-wksp-2015/session3/2-tunkel-508.pdf

    ... O - 1) Heat (melt) 2) Transfer H + 3) Cool (solidify) Limited Data - Read Across from BPA Flame Retardant Alternatives 26 Melamine (TBBPA AA) 27 Rat LD 50 >3,160 mg/kg Rat LD 50 ...

  11. Minutes: BSC TRRS; June 16, 1982 632KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1982/june/82june16trrsmin_508.pdf

    ... Melamine. D r . Highland, a p r i n c i p a l reviewer f o r the r e p o r t on t h e bioassay o f melamine, agreed w i t h t h e conclusion t h a t : "Under t h e c o n d i t i o ...

  12. Nomination Background: Decabromodiphenyl ether (CASRN: 1163-19... 246KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/cpscfrsnomination_supp_062_508.pdf

    ... as trimethylol melamine, phosphoric acid, and ethyleneurea (D'Ruiz 1998; Sanders 1978). ... These may include cleavage products of PA and/or PA-melamine adducts. The toxicology of PA ...

  13. Background Document for 1-Chloro-4-(trifluoromethyl)benzene;... 395KB

    https://ntp.niehs.nih.gov/ntp/noms/support_docs/pcbtf060409.pdf

    ... Epoxy, polyester, acrylic, silicone, ethyl silicate, phenolic varnish, vinyl butyral, melamine/urea formaldehyde, and nitrocellulose resin systems - Application areas: automotive ...

  14. TR-163: Calcium Cyanamide (CASRN 156-62-7) 3.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr163.pdf

    ... Calcium cyanamide can be dimerized to dicyandiamide, an intermediate for melamine, one of the basic ingredients in amino plastics and resins. Other products prepared from calcium ...

  15. RoC Background Document: Disperse Blue I; Nov. 18-19, 1996 2.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/disperse_blue_508.pdf

    ... et al., 1984). Chronic administration of melamine resulted in increased incidences of ... 1984. Urolithiasis and Bladder Carcinogenicity of Melamine in Rodents. Toxicol. Appl. ...

  16. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... TR-246 06/23/81 Asbestos, chrysotile(IR) 12001-29-5 HAMSTER = N TR-245 06/16/82 Melamine 108-78-1 P Clear Evidence N No Evidence N No Evidence N No Evidence TR-244 06/23/81 ...

  17. TOX-78: Triethylamine (CASRN 121-44-8) Administered by Inhalation... 3.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox078_508.pdf

    ... perchlorethylene and trichloroethylene 6 ; as an antilivering agent for urea- and melamine-based enamels; in the recovery of gelled paint vehicles; as an accelerator ...

  18. TR-299: C.I. Disperse Blue 1 (A commercial dye containing approximatel... 15.0MB

    https://ntp.niehs.nih.gov/go/tr299

    ... In a previous 2-year study of melamine (2,4,6- triamino-s-triazine), the presence of ... was obtained in the 2-year studies of melamine in which both male rats and mice ...

  19. RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf

    ... all polymers except in resinous and polymeric coatings complying with 21 CFR 175.300, melamine- formaldehyde resins in molded articles complying with 21 CFR 177.1460, ...

  20. RoC Profile: Formaldehyde; 15th RoC 2021 298KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/formaldehyde.pdf

    ... The predominant use (~55% of to- tal consumption) is in the production of industrial resins (mainly urea-formaldehyde, phenol-formaldehyde, polyacetal, and melamine- formaldehyde ...

  21. TR-173: Carbromal (CASRN 77-65-6) 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr173.pdf

    ... McGraw-Hill Book Co., New York, 1966. Roe, F.J.C., and M.H. Salaman, "Further Studies on Incomplete Carci- nogenesis: Triethylene Melamine (T.E.M.), 1,2-Benzanthracene and ...

  22. Background Document: RoC: Glass Wool Fibers; 2010 3.7MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/glasswoolbd20100408_508.pdf

    ... Binders, such as 9/9/09 5 RoC Background Document for Glass Wool Fibers phenol-formaldehyde resins, melamine, or acrylic resins, may serve to hold the fibers together. The binder ...

  23. Report of 2006 ICCVAM Peer Panel Meeting on In Vitro Cytotoxicity... 1.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/atpanelrpt06/atpanelrpt.pdf

    ... In addition, errors were made in the exclusion process based on the rules cited in the Draft BRD. For example, triethylene melamine and busulfan are both alkylating agents, but ...

  24. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... 0.00071 0.23 57.7 143 Triethylene melamine 0.00078 0.005 1.0 14 Mitomycin C 0.00084 ... 0.015 0.0037 1.0 143 Triethylene melamine 0.00078 0.005 1.0 177 Busulphan 0.046 ...

  25. Draft RoC Monograph Cobalt Appendix: RoC Peer Review; July 22... 1.7MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph_appen.pdf

    ... all polymers except in resinous and polymeric coatings complying with 21 CFR 175.300, melamine- formaldehyde resins in molded articles complying with 21 CFR 177.1460, ...

  26. Revised Draft RoC Monograph Cobalt Appendix: RoC Peer Review... 1.7MB

    https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt_append.pdf

    ... all polymers except in resinous and polymeric coatings complying with 21 CFR 175.300, melamine- formaldehyde resins in molded articles complying with 21 CFR 177.1460, ...

  27. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... 1990 Technical Report TR-245 PDF (8.12 MB) Carcinogenesis Bioassay of Melamine (CASRN 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) 1983 Technical Report TR-244 PDF ...

  28. TR-310: Marine Diesel Fuel (NO CAS) and JP-5 Navy Fuel (CASRN... 10.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr310.pdf

    ...,6-Dichloro-p-phenylenediamine 0/60 0/60 Melamine 0149 0147 TOTAL 01248 (0.0%) 1/247 ... Caprolactam Bisphenol A 11-Aminoundecanoic acid 2,6-Dichloro-p-phenylenediamine Melamine ...

  29. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Long-Term Carcinogenicity TR-245 PDF (8.12 MB) Carcinogenesis Bioassay of Melamine (CASRN 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) 1983 Long-Term Carcinogenicity ...

  30. Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf

    ... No Non- Hodgkin lymphoma 1 st First@wk 12 Vincristine, Procarbazine, Triethylene- melamine ... Vincristine, Triethylene- melamine -- -- Induced abortion at gestation wk ...

  31. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... 1990 Technical Report TR-245 PDF (8.12 MB) Carcinogenesis Bioassay of Melamine (CASRN 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) 1983 Technical Report TR-244 PDF ...

  32. CERHR Monograph: Potential Human Reproductive and Developmental... 5.4MB

    https://ntp.niehs.nih.gov/ntp/ohat/phthalates/bb-phthalate/bbp_monograph_final.pdf

    ... subcutaneous injections on days 1, 5, and 10 of the study at doses equivalent to 400-600, 1,280-1,840, and 3,200-4,560 mg/kg bw/day (triethylene melamine was the positive control). ...

  33. CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB

    https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf

    ... A negative control of saline and a positive control of 0.1 µg/mL triethylene melamine ... control of saline and a positive control of 0.3 mg/kg bw triethylene melamine were tested. ...

  34. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    ... and methacrylamide in combination with melamine-formaldehyde resin as a coating for ... Type: Notice July 15, 1988 53 FR 26886 5160-02-1 1988 EPA Melamine EPA proposed rule to ...

  35. Minutes: BSC; July 7, 2009 399KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2009/july/minutes20090724.pdf

    ... for contaminants in foods, namely, acrylamide, furan, and melamine plus cyanuric acid. ... pigs to identify biomarkers and the mechanism of action of melamine plus cyanuric acid. ...

  36. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf

    ... For example, scientists at Health Canada reported detecting melamine in liquid and ... However, in all instances, the concentrations of melamine detected were below the health ...

  37. ICCVAM Background Review Document (Vol 1): In Vitro Cytotoxicity... 16.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol1_nov2006.pdf

    ... 32.1 9827 180 3 -21.8 8.47 Triethylene- melamine Heterocyclic III 0.086 0.009 3 -0.567 ... NA NA - NA NA NA NA - NA NA Triethylene- melamine Heterocyclic III 1.69 0.950 3 -0.838 ...

  38. TR-457: Salicylazosulfapyridine (CASRN 599-79-1) in F344 Rats... 18.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr457.pdf

    ... Toxicology (NTP) ,Carcinogenesis of (CAS Bioassay Melamine No.108-78-1)inF344/NRatsandB6C3FlMice (Feed Study). Technical.Report Series No. 245.. NIH Publication No. 83-2501. U.S. ...

  39. TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf

    ... Further studies on incomplete carcinogenesis: Triethylene melamine (T.E.M.), ... Marine Diesel Fuel and JP-5 Navy Fuel Melamine 2-Mercaptobenzothiazole Mercuric ...

  40. TOX-59: Chloral Hydrate (CASRN 302-17-0) 10.8MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox059.pdf

    ... Prev. 9, 279-288. 57 3 1 Roe, F.J.C, and Salaman, M.H. (1955). Further studies on incomplete carcinogenesis: Triethylene melamine (T.E.M.), 1,2-benzanthracene and $-propiolactone, ...

  41. TR-452: 2,2-Bis(Bromomethyl)-1,3-Propanediol (FR-1138) (CASRN... 31.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr452.pdf

    ... irritation, and tumor formation (e.g., melamine; NTP, 1983), but this does not appear to ... Carcinogenesis Bioassay of Melamine (CAS No. 108-78-1) in F344/N Rats and B6C3F~ Mice ...

  42. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... NA 57.7 0.23 251.08 0.23 143 Triethylene melamine 51-18-3 0.16 0.00078 1.0 0.005 14.9 ... 10.0 0.037 271.49 0.0037 143 Triethylene melamine 51-18-3 0.16 0.00078 1.0 0.005 14.9 ...

  43. TR-503: Chloral Hydrate (Ad Libitum and Dietary Controlled) ... 5.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr503.pdf

    ... Toxicol. 31, 225-229. 73 Chloral Hydrate, NTP TR 503 Roe, F.J.C., and Salaman, M.H. (1955). Further studies on incomplete carcinogenesis: Triethylene melamine (T.E.M.), ...

  44. TR-366: Hydroquinone (CASRN 123-31-9) in F344/N Rats and B6C3F1Mice... 14.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr366.pdf

    ... Toxicol. 24:590-596. 103. Roe, F.J.C.; Salaman, M.H. (1955) Further studies on incomplete carcinogenesis: Triethyl- ene melamine (T.E.M.), 1,2-benzanthracene and D-propiolactone as ...

  45. ICCVAM Test Method Evaluation Report: In Vitro Cytotoxicity Test... 14.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/at-tmer-complete.pdf

    ... In addition, errors were made in the exclusion process based on the rules cited in the Draft BRD. For example, triethylene melamine and busulfan are both alkylating agents, but ...

  46. TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf

    ... Ziram Bis(2-chloro-1methylethy1)ether Propyl Gallate Diallyl Phthalate (Mice) Polybrominated Biphenyl Mixture Melamine L-Ascorbic Acid 4,4'-Methylenedianiline Dihydrochloride ...

  47. TR-383: 1-Amino-2,4-Dibromoanthraquinone (CASRN 81-49-2) in F344... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr383.pdf

    ... Relationship between calculus formation and carcinogenesis in the urinary bladder of rats administered the non- genotoxic agents, thymine or melamine. Carcinogenesis 13, 1043-1045. ...

  48. TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf

    ... Propyl Gallate Diallyl Phthalate (Mice) Trichlorethylene (Rats and Mice) Polybrominated Biphenyl Mixture Melamine Chrysotile Asbestos (Hamsters) L-Ascorbic Acid 4,4' ...

  49. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    ... (Mice) 243 Trichlorethylene (Rats and Mice) 244 Polybrominated Biphenyl Mixture 245 Melamine 246 Chrysotile Asbestos (Hamsters) 247 L-Ascorbic Acid 248 4,4' -Methylenedianiline ...

  50. TR-289: Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1Mice... 16.4MB

    https://ntp.niehs.nih.gov/go/tr289

    ... Submitted for pub- lica tion. 136. Roe, F.; Salaman, M. (1955) Further studies on incomplete carcinogenesis: Triethylene melamine (T.E.M.), 1,2-benzanthracene and p- propiolactone ...

 
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