Skip to Main Navigation Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

We welcome your feedback!

Contact us with your comments.

QUICK TIPS
 
of 4

Refine

  • Categories
  • Content Type
  • Reports and Publications
  • Years
  • Formats

Search suggestions for "108-90-7".

  1. CEBS Data Related to Chlorobenzene (108-90-7) https://cebs.niehs.nih.gov/cebs/test_article/108-90-7


164 results found for "108-90-7".

  1. TR-261: Chlorobenzene (CASRN 108-90-7) in F344/N Rats and B6C3F1Mice... 10.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr261.pdf

    1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHLOROBENZENE (CAS NO. 108-90-7) IN F344/N RATS AND 86C3ft MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...

  2. Abstract for TR-261 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr261

    Abstract for TR-261 Toxicology and Carcinogenesis Studies of Chlorobenzene in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 108-90-7 Chemical Formula: C6H5Cl Molecular ...

  3. Target Organs and Levels of Evidence for TR-261 57KB

    https://ntp.niehs.nih.gov/data/tr/200s/tr261levels

    Target Organs and Levels of Evidence for TR-261 Toxicology and Carcinogenesis Studies of Chlorobenzene (CASRN 108-90-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical ...

  4. Minutes: BSC TRRS; Feb 28, 1983 601KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1983/feb/83feb28trrsmins_508.pdf

    chloroform) 1,2-Di chl oropropane Chlorobenzene Di glyci dyl resorci no1 e t h e r ... Chlorobenzene. D r . Scala, a p r i n c i p a l r e v i e w e r f o r t h e r e p o r t ...

  5. TR-319: 1,4-Dichlorobenzene (CASRN 106-46-7) in F344/N Rats and... 17.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr319.pdf

    ... No clear hematologic changes were observed in female rats. 1,4-Di- chlorobenzene produced ... J. Barter, representing the Chlorobenzene Producers Association, made several comments on ...

  6. Abstract for TR-189 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr189

    Names: 4-chlorobenzeneamine; 4-chlorophenylamine; 4-chloroaniline; 4-CA; 1-amino-4-chlorobenzene Report Date: 1979 Full Report PDF Abstract p-Chloroaniline, a dye and chemical ...

  7. TOX-6: Pentachlorobenzene (CASRN 608-93-5) 3.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox006.pdf

    ... Penta- chlorobenzene melts at 86° C and boils at 277° C at atmospheric pressure. Its ... et al., 1979; Strik, 1986). Penta- chlorobenzene is estimated to have a half-life of ...

  8. TOX-7: 1,2,4,5-Tetrachlorobenzene (CASRN 95-94-3) 4.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox007.pdf

    ... Commercial production of 1,2,4,5-tetra- chlorobenzene in the United States ceased in 1983 ... Environmental contamination by 1,2,4,5-tetra- chlorobenzene can occur via leaching from ...

  9. Abstract for TR-187 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr187

    5-chloro-2-methylaniline; 2-methyl-5-chloroaniline; 1-amino-2-methyl-5-chlorobenzene; 1-amino-3-chloro-6-methylbenzene; Fast Red KB Base; Azogene Fast Red KB; ...

  10. RoC Profile: 1,4-Dichlorobenzene; 15th RoC 2021 149KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dichlorobenzene.pdf

    ... Other uses of 1,4-di- chlorobenzene include use as a germicide or disinfectant; a soil ... production, captive use, and shipment of 1,4-di- chlorobenzene from producers (NTP 1987). ...

  11. Abstract for TR-351 69KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr351

    CASRN: 20265-96-7 Chemical Formula: C6H6NCl . HCl Molecular Weight: 164.1 Synonyms/Common Names: 1-Amino-4-chlorobenzene hydrochloride; 4-chlorophenylamine hydrochloride; ...

  12. RoC Profile: Hexachlorobenzene; 15th RoC 2021 155KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/hexachlorobenzene.pdf

    the rela- tionship between human cancer and exposure specifically to hexa- chlorobenzene. ... higher serum concentrations of hexa- chlorobenzene than among women with the lowest serum ...

  13. Abstract for TOX-14 63KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox014

    ...hlorobenzotrifluoride; benzene, 1-chloro-4-(trifluoromethyl)-; p-(trifluoromethyl) chlorobenzene; p-chlorobenzotrifluoride; p-chlorotri-fluoromethylbenzene; p-trifluoromethylphenyl ...

  14. TOX-35: Chemical Mixture of 25 Groundwater Contaminants 11.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox35.pdf

    ... 0 .54 0 .012 0 .04 0 .12 0 .4 Chlorobenzene 0 .1 0 .003 0 .01 0 .03 0 .1 Chlorofo ... 56-23-5 0 .54 0 .012 0 .04 0 .12 0 .4 Chlorobenzene 108-90-7 0 .1 0 .003 0 .01 0 .03 0 .1 ...

  15. TR-351: para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in... 12.2MB

    https://ntp.niehs.nih.gov/go/tr351

    ... weight 164.1 Synonyms: 1-amino-4-chlorobenzene hydrochloride; 4-chlorophenylamine ... HCl Molecular weight 164.1 ~:ynonyms: 1-amino-4-chlorobenzene hydrochloride; ...

  16. ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf

    ... LLNA EC3 (%) (Max. SI) 3 LLNA: DA EC1.8 (%) (Max. SI) 3 Chlorobenzene 5 Manufacturing; ... SI values between 1.8 and 2.5 (chlorobenzene maximum SI = 2.44; hexane maximum SI = ...

  17. Presentation: A Quantitative AOP for Skin Sensitization 1.5MB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/maxwell-508.pdf

    ET AL. 1983 MODELLING SKIN BIOAVAILABILITY OF EXPERIMENTAL SENSITISER 2,4-DI-NITRO CHLOROBENZENE (DNCB) Loss from skin Loss from formulation Partitioning Diffusion Exposure ...

  18. RoC Profile: Dichlorodiphenyltrichloroethane; 15th RoC 2021 155KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dichlorodiphenyltrichloroethane.pdf

    ... It is practically insoluble in water, but it is soluble in many organic solvents, including acetone, benzene, benzyl benzoate, carbon tetrachloride, chlorobenzene, cyclohexanone, ...

  19. RoC Profile: 2,3,7,8-Tetrachlorodibenzo-p-dioxin; 15th RoC 2021 154KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/tetrachlorodibenzodioxin.pdf

    ... It is insoluble in water and very slightly soluble in o-dichloro- benzene, chlorobenzene, ... Fires involving capacitors or transformers containing chlorobenzene and PCBs are potential ...

  20. TR-255: 1,2-Dichlorobenzene (o-Dichlorobenzene) (CASRN 95-50... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr255.pdf

    ... Chlorobenzene, bromobenzene, iodobenzene, and 1,2dichlorobenzene, administered to rats as ... How- ever, recent work has shown that, although hexa- chlorobenzene causes porphyria in ...

  21. TR-501: p,p'-Dichlorodiphenyl Sulfone (CASRN 80-07-9) in F344... 13.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr501.pdf

    ... sulfone; 1,1N-sulfonylbis (4-chlorobenzene) p,pN-Dichlorodiphenyl sulfone is used ... sulfone; 1,1N-sulfonylbis (4-chlorobenzene) CHEMICAL AND PHYSICAL PROPERTIES ...

  22. RoC Background Document: 2,3,7,8-Tetrachlorodibenzo-p-dioxin... 7.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrachl_tcdd_4apps_508.pdf

    ... giL in dichlorobenzene 0.72 giL in chlorobenzene 0.57 giL in benzene 0.37 giL in ... It is soluble in a-dichlorobenzene, chlorobenzene, benzene, and chloroform. TCDD is ...

  23. Presentation: The Murine Local Lymph Node Assay: DA 1010KB

    https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf

    ... gallate Resorcinol Sodium lauryl sulfate Trimellitic anhydride 1-Bromobutane Chlorobenzene Diethyl phthalate Dimethyl isophthalate Hexane Isopropanol Lactic acid Methyl ...

  24. Abstract for TOX-35 74KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox035

    ... 12.5 Cadmium 0.85 1.53 5.1 15.3 51 Carbon tetrachloride 0.54 0.012 0.04 0.12 0.4 Chlorobenzene 0.1 0.003 0.01 0.03 0.1 Chloroform 1.46 0.21 0.7 2.1 7 Chromium 0.69 1.08 3.6 10.8 ...

  25. Protocol: Evidence Map of Inflammation-Based Atherosclerosis... 643KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosis_supplementaljuly2023_508.pdf

    ... OR chlorinated-hydrocarbons[tiab] OR chlorobenzene*[tiab] OR chlorofluorocarbon*[tiab] OR ... OR chlorinated-hydrocarbons OR chlorobenzene* OR chlorofluorocarbon* OR ...

  26. Minutes: BSC TRRS; March 26, 1986 432KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1986/mar/86mar26trrsmins_508.pdf

    ... D r . J. Barter, representing the Chlorobenzene Producers Association, made several comments on the Technical Report. He opined t h a t the differences reported between the i n h a ...

  27. TR-187: 5-Chloro-o-toluidine (CASRN 95-79-4) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr187.pdf

    ... 2-amino-4-chlorotoluene; o-amino-p-chlorotoluene; 5-chloro-2-methyl- aniline; 2-methyl-5-chloroaniline; l-amino-2-methyl-5-chlorobenzene; l-amino-3-chloro-6-methylbenzene; Fast. ...

  28. TR-189: p-Chloroaniline (CASRN 106-47-8) 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr189.pdf

    ... * It is also called 4-chlorophenylamine; 4-chloroaniline; 4-CA; and 1-amino-4- chlorobenzene. p-Chloroaniline 1s used in the manufacture of at least 10 dyes and pigments; C.I. ...

  29. TOX-33: 2-Chloronitrobenzene (CASRN 88-73-3) and 4-Chloronitrobenzene... 10.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox33.pdf

    ... The two isomers of chloronitrobenzene are manufactured by reacting chlorobenzene with ... The nitration of chlorobenzene was carried out in a large tank, and the resulting hot oil ...

  30. Reproducing the ITS-2 Model Using R 472KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/its-os/its2_r_version-508.pdf

    ... 0.072281 0.003438 0.391915 0.532366 108-90-7 0.939476 0.027764 0.000313 0.032447 ... 0.072281 0.003438 0.391915 0.532366 108-90-7 0.939476 0.027764 0.000313 0.032447 ...

  31. ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf

    ... three additional substances (xylene, chlorobenzene, and nickel chloride) and repeat tests ... DMF + 24 (5.5) 1 DMF + NA (1.6) 1 Chlorobenzene 4 AOO - NA (1.7) 1 NT NT NT NT ...

  32. TR-325: Pentachloronitrobenzene (CASRN 82-68-8) in B6C3F1Mice... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr325.pdf

    ... zene used in these NTP studies was greater than 99% pure and contained less than 0.07% hexa- Through its use as a fungicide, pentachloronitro- chlorobenzene (Appendix D). ...

  33. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf

    ... LB40373 98-06-6 1956.2 Chlorobenzene LB93949 109-90-7 1977.3 ... 4-Chloroaniline 106-47-8 127.57 Chlorobenzene 108-90-7 112.56 Chloroethane 75-00-3 ...

  34. TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf

    ... at Battelle Columbus Laboratories Chlorobenzene 0/50 N-P henyl-2-Naphthylamine 1/50 ... Historical Incidence et Battelle Columbus Laboratorks Chlorobenzene 0150 0/50 0150 ...

  35. Recommended Performance Standards for the LLNA 2.2MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf

    ... NC +/+ +/+ 13 Methyl methacrylate 80-62-6 Liq AOO 90 1 45-100 NC +/+ +/+ 14 Chlorobenzene 108-90-7 Liq AOO NA 1 NA NA -/- -/* 15 Isopropanol 67-63-0 Liq AOO NA 1 NA NA -/- -/+ 16 ...

  36. TR-333: N-Phenyl-2-naphthylamine (CASRN 135-88-6) in F344/N Rats... 9.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr333.pdf

    ... Historical Incidence at Battelle Columbus Laboratories Chlorobenzene 0149 6/49 6/49 Common ... at Battelle Columbus Laboratories Chlorobenzene Common control group (b) C.I. Disperse ...

  37. OECD Test Guideline 429: Skin Sensitisation: Local Lymph Node... 291KB

    https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-tg429-2010.pdf

    ... NC +/+ +/+ 13 Methyl methacrylate 80-62-6 Liq AOO 90 1 45-100 NC +/+ +/+ 14 Chlorobenzene 108-90-7 Liq AOO 25 1 NA NA -/- -/* 15 Isopropanol 67-63-0 Liq AOO 50 1 NA NA -/- -/+ 16 ...

  38. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... EE Equivocal Evidence SE Some Evidence SE Some Evidence TR-261 02/28/83 Chlorobenzene 108-90-7 E Equivocal Evidence N No Evidence N No Evidence N No Evidence TR-259 02/28/83 ...

  39. RoC Profile: Pentachlorophenol and By-products of Its Synthesis... 220KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/pentachlorophenol.pdf

    ... Chlorinated compounds whose metabolism can give rise to penta- chlorophenol include hexachlorobenzene, penta chlorobenzene, pen- tachloronitrobenzene, pentachloro cyclohexene, ...

  40. Minutes: BSC; June 29, 1995 2.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1995/june/19950629bscmins_508.pdf

    ... Schuman agreed that this was equivalent to scientific judgment. (6) Dr . James Sherman, Monsanto, representing the Chlorobenzene Producers Association (CPA), said the CPA supports ...

  41. TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf

    ... male Drosophilameianogaster with 1,2,4,5-tetra- chlorobenzene (maximum dose, 755.6 pg/mL). ... Acrylate 328 Methyl Carbamate 2 6 1 Chlorobenzene 1,2-Epoxybutane 329 263 ...

  42. TR-289: Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1Mice... 16.4MB

    https://ntp.niehs.nih.gov/go/tr289

    ... a t Battelle Columbus Laboratories Chlorobenzene o-Dichlorobenzene 0150 0150 1/50 0150 ... a t Battelle Columbus Laboratories Chlorobenzene 5/50 2/50 7/50 o-Dichlorobenzene 1/50 ...

  43. CERHR Monograph: Potential Human Reproductive and Developmental... 1.0MB

    https://ntp.niehs.nih.gov/ntp/ohat/bromopropanes/2-bromopropane/2bp_monograph.pdf

    ... Following soil excavation and continuous groundwater pumping for 7 years, substantial concentrations of bromobenzene and chlorobenzene were found, but neither 1- nor 2-BP nor their ...

  44. TR-309: Decabromodiphenyl Oxide (CASRN 1163-19-5) In F344/N Rats... 17.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr309.pdf

    ... 425"C 3.0 5 mm Hgat306"C Water: 20-30 ppb Cottonseed oil: 600 ppm Acetone: 500 ppm Chlorobenzene: 6,000 ppm a-Xylene: 8,700 ppm Decabromodiphenyl oxide, 77.4% Nonabromodiphenyl ...

  45. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... Basketter and Scholes (1992); Ashby et al. (1995); Basketter et al. (1996a) Chlorobenzene 108-90-7 aryl halide synthetic organic intermediate// manufacture of phenol, aniline, ...

  46. CERHR Monograph: 1-Bromopropane 1.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/bromopropanes/1-bromopropane/1bp_monograph.pdf

    ... Follow- ing soil excavation and continuous groundwater pumping for 7 years, substantial concentrations of bromobenzene and chlorobenzene were found, but neither 1-BP, nor 2-BP, nor ...

  47. TR-320: Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1Mice... 11.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr320.pdf

    ... at Battelle Columbus Laboratories Chlorobenzene Pooled control group (b) C.I. Disperse ... at Battelle Columbus Laboratories Chlorobenzene Pooled control group (c) C.I. Disperse ...

  48. TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB

    https://ntp.niehs.nih.gov/go/tr349

    ... at Battelle Columbus Laboratories Chlorobenzene 7/50 14/50 N-Phenyl-2-naphthylamine 6/... at Battelle Columbus Laboratories Chlorobenzene N-Phenyl-2-naphthylamine C.I. Disperse ...

  49. Background Document: RoC: Styrene; 2010 4.3MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/styrene_final_508.pdf

    ... methylene dichloride, benzene, toluene, ethylbenzene, and chlorobenzene are suitable. ... carbon tetrachloride, ethyl chloride, methylene dichloride, and chlorobenzene. ...

  50. TR-521: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) (CASRN 1746... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr521.pdf

    ... in n-octanol, methanol, and lard oil, and soluble in organic solvents including o-dichlorobenzene, chlorobenzene, benzene, and chloroform (IARC, 1997; Lewis, 1997; ATSDR, 1998). ...

 
of 4