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Abstract for TR-470 78KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr470
It is used in the production of piperidine, an intermediate in the manufacture of rubber and mepiquat chloride, and as an intermediate and solvent in the preparation of vitamins ...
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TR-470: Pyridine (CASRN 110-86-1) in F344/N Rats, Wistar Rats... 16.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr470.pdf
... It is used in the production of piperidine, an inter- mediate in the manufacture of rubber ... It is used in the production of piperidine, an intermediate in the manufacture of rubber ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... imide 2 Piperazine 2 Diphenylalkane 3 Piperidine 2 Diphenylalkene 3 Polycyclic aromatic ... intermediate Cycloheximide 66-81-9 Piperidine; Glutaramide Pharmaceutical 22 Proposed ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
... 4-nitrosomorpholine see N-Nitrosamines: 15 Listings, N-Nitrosomorpholine 1-nitroso-piperidine see N-Nitrosamines: 15 Listings, N-Nitrosopiperidine 3-(1-nitroso-2-pyrrolidinyl)pyr...
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RoC Profile: Nitrosamines; 15th RoC 2021 374KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrosamines.pdf
... the re- lationship between human cancer and exposure specifically to N-nitroso piperidine. ... was first prepared in 1863 by the action of ni- trogen dioxide on piperidine (IARC 1978). ...
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TR-331: Malonaldehyde, Sodium Salt (3-Hydroxy-2-propenal, Sodium... 7.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr331.pdf
... Malonaldehyde in the presence of nitrite has been reported to facilitate the formation of ni- trosamines from dimethylamine, diethylamine, piperidine, pyrrolidine, and morpholine ...
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TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf
... for the therapeuticaction of the drug (Maxwell et al., 1970; Patrick et al., 1987). Methylphenidate hydrochloride a is piperidine derivative structurally related to amphetamine. ...
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CERHR Monograph: Methylphenidate 11.6MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/methylphenidate/methylphenidatemonograph.pdf
... form.methylphenidate.to.α-phenyl-piperidine.acetic.acid.(commonly.called.ritalinic....otransform.methylphenidate.to.α-phenyl-piperidine.acetic. acid. (commonly. called. ...
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Appendices A-G; 15th RoC 2021 448KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf
... 4-nitrosomorpholine see N-Nitrosamines: 15 Listings, N-Nitrosomorpholine 1-nitroso-piperidine see N-Nitrosamines: 15 Listings, N-Nitrosopiperidine 1-nitrosopyrrolidine see ...
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Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
... Tetrachlorvinphos organophosphate pesticide - Piperidene solvent 110-89-4 Mercuric ... Class 1 (200 - 2000 mg/kg) Sodium pentachlorophenate 309 25 1 Piperidine 488 24 2 ...
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Submission of the CertiChem Cell Proliferation Test Method for... 3.1MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/submdoc.pdf
... 97.5% Fluka Cycloheximide* 66-81-9 Piperidine; Glutaramide 1E-4 - 1E-12 98.0% Sigma ... amine; triazine Cycloheximide 66-81-9 Piperidine; Glutaramide NG - ND - Protein ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... Chemical Cycloheximide 66-81-9 Piperidine; Glutaramide Pharmaceutical 4.00E+07 - ... Heterocycle; Pyrimidine 2062-78-4 Piperidine; Benzimidazole 32809-16-8 ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... Chemical Cycloheximide 66-81-9 Piperidine; Glutaramide Pharmaceutical 4.00E+07 - ... Heterocycle; Pyrimidine 2062-78-4 Piperidine; Benzimidazole 32809-16-8 ...
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ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... methylphenyl)-n-methyl-1- piperidine-carboxamide monomethane-sulfonate - ... 2-methylphenyl)-n- methyl-1- piperidine- carboxamide monomethane- sulfonate ...
