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TR-515: Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7... 9.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr515.pdf
THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF PROPYLENE GLYCOL MONO-t-BUTYL ETHER (CAS NO. 57018-52-7) IN F344/N RATS AND B6C3F 1 MICE AND A TOXICOLOGY STUDY OF PROPYLENE GLYCOL ...
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TR-267: Propylene Oxide (CASRN 75-56-9) in F344/N Rats and B6C3F1Mice... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr267.pdf
AND CARCINOGENESIS STUDIES OF PROPYLENE OXIDE (CAS NO. 75-56-9) IN F344/N RATS ... NCI, was transferred to the NIEHS. Propylene Oxide, NTP TR 267 NTP TECHNICAL REPORT ...
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TR-272: Propylene (CASRN 115-07-1) in F344/N Rats and B6C3F1Mice... 8.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr272.pdf
Technical Report Series No. 272 3 c TOXICOLOGY AND CARCINOGENESIS STUDIES OF PROPYLENE (CAS NO. 115-07-1) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) U.S. DEPARTMENT OF ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf
and Developmental Effects of Propylene Glycol March 2004 NIH Publication No. ......... vi NTP Brief on Propylene Glycol ......
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RoC Profile: Propylene Oxide; 15th RoC 2021 196KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/propyleneoxide.pdf
Propylene Oxide CAS No. 75-56-9 Reasonably anticipated to be a human carcinogen First ... Also known as 2-methyloxirane O CH 3 Carcinogenicity Propylene oxide is reasonably ...
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Abstract for TR-515 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr515
Toxicology and Carcinogenesis Studies of Propylene Glycol Mono-t-Butyl Ether in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Propylene Glycol Mono-t-Butyl Ether in Male NBR ...
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Abstract for TR-272 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr272
Abstract for TR-272 Toxicology and Carcinogenesis Studies of Propylene in F344/N Rats and B6C3F1 Mice (Inhalation Studies) CASRN: 115-07-1 Chemical Formula: C3H6 Molecular Weight: ...
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Abstract for TR-267 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr267
Toxicology and Carcinogenesis Studies of Propylene Oxide in F344/N Rats and B6C3F1 Mice ... Full Report PDF Abstract Propylene oxide is a volatile, colorless liquid used as an ...
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Abstract for RACB84068 60KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84068
8abs Abstract for RACB84068 Propylene Glycol: Reproduction and Fertility Assessment in ... Propylene glycol, a common solvent used in industry, food, and in consumer goods, was ...
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Abstract for RACB85069 60KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb85069
9abs Abstract for RACB85069 Propylene Glycol Monomethyl Ether: Reproduction and Fertility ... Propylene glycol monomethyl ether (PGME), a solvent used in industry, was tested for ...
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Target Organs and Levels of Evidence for TR-515 59KB
https://ntp.niehs.nih.gov/data/tr/500s/tr515levels
Toxicology and Carcinogenesis Studies of Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Propylene Glycol ...
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Target Organs and Levels of Evidence for TR-272 56KB
https://ntp.niehs.nih.gov/data/tr/200s/tr272levels
Target Organs and Levels of Evidence for TR-272 Toxicology and Carcinogenesis Studies of Propylene (CASRN 115-07-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) Chemical ...
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Abstract for TR-191 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr191
Abstract Bis(2-chloro-1-methylethyl) ether is a beta-haloether and a byproduct of propylene oxide and propylene glycol manufacture. A bioassay of technical grade ...
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Abstract for TR-477 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr477
Chlorohydrin; 1-chloro-2-hydroxypropane; 1-chloroisopropyl alcohol; propylene-delta-chlorohydrin; sec-propylene chlorohydrin Report Date: September 1998 Full Report PDF Abstract ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 4.3MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/ethylene/eg_monograph.pdf
Appendix I. NTP-CERHR Ethylene Glycol / Propylene Glycol Expert Panel Preface ... member agencies, recommended ethylene glycol and propylene glycol for expert panel review. ...
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Target Organs and Levels of Evidence for TR-267 59KB
https://ntp.niehs.nih.gov/data/tr/200s/tr267levels
Toxicology and Carcinogenesis Studies of Propylene Oxide (CASRN 75-56-9) in F344/N Rats .../Exposure Levels Study Laboratory 1,2-Propylene oxide 75-56-9 06/29/1983 Inhalation ...
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Minutes: BSC TRRS; May 22, 2003 842KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2003/may/trrs22may2003mins_508.pdf
Propylene Glycol Mono-t-butyl Ether ......MaryS. Wolfe, Executive Secretary, at 919-541-3971 or wolfe@niehs.nih.gov. Propylene ...
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Abstract for TR-542 78KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr542
Cumene is produced in a modified Friedel-Crafts reaction process that uses acidic catalysts to alkylate benzene with propylene. Cumene is the principal chemical used in the ...
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Abstract for RACB88075 61KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb88075
and is also formed in foods following fumigation with propylene oxide, was tested for its effects on reproduction and fertility in Sprague-Dawley rats using the RACB protocol. ...
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Abstract for TR-239 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr239
Bis (2-chloro-1- methylethyl) ether has been a by-product in the manufacture of propylene oxide and propylene glycol. It is the active ingredient of a nematocide developed and used ...
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RoC Background Document: Ethylene Oxide; Dec. 2-3, 1998 4.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/ethyloxide_oneapp_508.pdf
......... 51 6.5.11,2-Propylene Oxide ......alkyl phenols, cellulose, starch, poly(propylene glycol), and ethylene carbonate. ...
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TR-477: 1-Chloro-2-Propanol (Technical Grade) (CASRN 127-00-4... 9.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr477.pdf
... Chlorohydrin, 1-chloro-2-hydroxypropane, 1-chloroisopropyl alcohol, propylene-%-chlorohydrin, sec-propylene chlorohydrin 1-Chloro-2-propanol and its positional isomer, ...
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West Virginia Chemical Spill 92KB
https://ntp.niehs.nih.gov/whatwestudy/topics/wvspill
Dimethyl 1,4-cyclohexanedicarboxylate Propylene glycol phenyl ether Dipropylene glycol ... The chemicals dipropyleneglycol phenyl ether (DiPPH) and propylene glycol phenyl ether ...
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TR-511: Dipropylene Glycol (CASRN 25265-71-8) in F344/N Rats... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr511.pdf
... 2,2N-dihydroxyisopropyl ether; di-1,2-propylene glycol; dipropylene glycol (6CI); ... 2,2N-dihydroxyisopropyl ether; di-1,2-propylene glycol; dipropylene glycol (6CI); ...
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WV Spill: 5-Day Rat Toxicogenomic Studies; June 2015 Update 205KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/micronucleus_update_508.pdf
4-methylcyclohexanemethanol (MCHM), propylene glycol phenyl ether (PPH), or a ... 4- methylcyclohexanemethanol (MCHM), propylene glycol phenyl ether (PPH), and crude ...
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WV Spill: TGMX Update; July 2016 246KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/tgmx_update_july2016_508.pdf
4-methylcyclohexanemethanol (MCHM), propylene glycol phenyl ether (PPH), or the ... 4- methylcyclohexanemethanol (MCHM), propylene glycol phenyl ether (PPH), and crude ...
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TOX-36: Pesticide/Fertilizer Mixtures 5.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox036.pdf
... The mixtures were administered in drinking water (with 512 ppm propylene glycol) to F344/N ... The California mixture stock consisted of eight organic components in propylene glycol, ...
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RoC Review of Cumene 71KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/cumene
An alkylated benzene that is a natural component of petroleum and can also be synthesized from propylene and benzene. Used primarily to produce phenol and acetone (accounting for ...
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Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
... Proliferating Cell Nuclear Antigen PG Propylene glycol PRP ICCVAM Peer Review Panel ... (DMF), methyl ethyl ketone (MEK), propylene glycol (PG), dimethyl sulfoxide (DMSO), ...
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1-Bromopropane: Preliminary Literature Search Strategy and List... 639KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/1-bp-litsearch&references5oct2012_508.pdf
... Phase I metabolites and their synonyms propylene oxide, n-propanol, glycidol, and 3- ... in combination with ethylene oxide or propylene oxide in human fibroblasts. ...
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WV Spill: NTP Research Project Plan Summary 79KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/wvprojectsummary_508.pdf
The spilled liquid was primarily the chemical 4-methylcyclohexanemethanol (MCHM). Other chemicals, including dipropylene glycol phenyl ether (DiPPH) and propylene glycol phenyl ...
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Abstract for TER91032 60KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91032
propylene glycol, where X was the median concentration of the components observed in groundwater determination in IOWA. A vehicle control formulation containing 512 ppm propylene ...
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Agenda: BSC TRRS; May 22, 2003 89KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2003/may/trrs22may2003agenda_508.pdf
Mary Anna Thrall, Board Chair Colorado State University Chemical/CAS # Report Number Primary Use, Route & Species Propylene Glycol Mono-t-butyl Ether 57018-52-7 TR 515 solvent ...
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Poster: Assessment of Genotoxic Potential of Elk River Chemical... 623KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/auerbach_sot_201603_508.pdf
were also identified, including propylene glycol phenyl ether (PPH) and its ... ether [DiPPH, 51730-94-0] X X X X X b Propylene glycol phenyl ether [PPH, 770-35-4] X X ...
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WV Spill: 5-Day Toxicogenomic Studies: In Vivo Micronucleus Assay... 130KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/micronucleus_wvfeb2015_508.pdf
primary chemical in the spilled liquid; propylene glycol phenyl ether (PPH); and crude ... These chemicals were 4- methylcyclohexanemethanol (MCHM), propylene glycol phenyl ether ...
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Abstract for TR-509 71KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr509
2,4-hexadienal; 2,4-hexadien-1-al; 2,4-Hx; 1,3-pentadiene-1-carboxaldehyde; 2-propylene acrolein; sorbaldehyde; sorbic aldehyde Report Date: October 2003 Full Report PDF ...
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Abstract for TR-263 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr263
(Propylene Dichloride)in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 78-87-5 Chemical Formula: C3H6Cl2 Molecular Weight: 112.99 Synonyms/Common Names: Propylene ...
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Abstract for TR-511 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr511
ether; 2,2N-dihydroxydipropyl ether; 2,2n-dihydroxyisopropyl ether; di-1,2-propylene glycol; dipropylene glycol (6CI); dipropyl glycol; oxybis-propanol; oxydipropanol; ...
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WV Spill: NTP Research Project Plan 185KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/project_508.pdf
ether (DiPPH) and propylene glycol phenyl ether (PPH) at less than 10 percent by weight. ... ether [DiPPH, 51730-94-0] X X X X X b Propylene glycol phenyl ether [PPH, 770-35-4] X X ...
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WV Spill: High Throughput Screening Assays; Dec. 2014 NTP Update 149KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/hts_wvupdate_508.pdf
4 ---methylcyclohexanemethanol (MCHM), 1 ,4---cyclohexanedimethanol ( CHDM), d imethyl 1 ,4---cyclohexanedicarboxylate ( DMCHDC), a nd propylene g lycol p henyl e ther ( PPH). ...
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TR-072: Phenoxybenzamine Hydrochloride (CASRN 63-92-3) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr072.pdf
... The vehicle used for most of the period of the bioassay was 6% propylene glycol in saline, ... saline only for one week, and 6% propylene glycol in saline for the remaining 37 weeks. ...
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TR-542: Cumene (CASRN 98-82-8) in F344/N Rats and B6C3F1 Mice... 9.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr542.pdf
... reac- tion process that uses acidic catalysts to alkylate benzene with propylene. ... reaction process that uses acidic catalysts to alkylate benzene with propylene. ...
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Abstract for TOX-36 63KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox036
The Iowa mixture contained alachlor, atrazine, cyanazine, metolachlor, metribuzin, and ammonium nitrate. The mixtures were administered in drinking water (with 512 ppm propylene ...
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Abstract for TR-72 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr072
The vehicle used for most of the period of the bioassay was 6% propylene glycol in saline, although other vehicles, including 0.05% polysorbate 80 in saline, were used at the ...
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ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf
... Sulfur Compounds NC (1.0) NC (1.3) Propylene glycol Cosmetics; Food additive; ... 0.94, 0.98, 1.01, 1.57, 2.04, 2.22 1.70 Propylene glycol (2,1) AOO/Water 0.87, 1.57 1.60 ...
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WV Spill: Nematode (Caenorhabditis elegans) Toxicity Study; March... 201KB
https://ntp.niehs.nih.gov/ntp/research/areas/wvspill/celegans_wvupdate_march2015_508.pdf
d ipropylene g lycol e ther ( DiPPH), propylene g lycol p henyl e ther ( PPH), 1 ... phenyl e ther ( DiPPH) a 770---35---4 Propylene glycol p henyl ether (PPH) a ...
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Eye, Cornea - Necrosis - Nonneoplastic Lesion Atlas 288KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Cornea-Necrosis
Carcinogenesis Studies of Propylene Glycol Mono-t-butyl Ether (CAS No. 57018-52-7) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Propylene Glycol Mono-t-butyl Ether In ...
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Eye, Cornea - Necrosis 209KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/crnecr/eye-cornea-necrosis_508.pdf
Carcinogenesis Studies of Propylene Glycol Mono-t-butyl Ether (CAS No. 57018-52-7) In F344/N Rats and B6C3F 1 Mice and a Toxicology Study of Propylene Glycol Mono-t-butyl Ether ...
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Minutes: BSC; June 16, 2015 579KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2015/june/bsc_jun2015_minutes_508-.pdf
... and outcomes of interest PPH propylene glycol phenyl ether SAR ... other minor constituents from crude MCHM and stripped propylene glycol phenyl ether (PPH). ...
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TR-329: 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr329.pdf
... in the same lesions in male rats and in pre- vious NTP studies of propylene oxide. Dr. ... Starting December 22, 1981, a stan- dard gas, 25 ppm propylene in air, was used to ...
