-
TR-062: Endosulfan (CASRN 115-29-7) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr062.pdf
National Cancer Institute CARCINOGENESIS Technical Report Series No. 62 1978 BIOASSAY OF ENDOSULFAN FOR POSSIBLE CARCINOGENICITY CAS No. 115-29-7 NCI-CG-TR-62 U.S. DEPARTMENT OF ...
-
Endosulfan: Target Organs and Levels of Evidence for TR-062 56KB
https://ntp.niehs.nih.gov/data/tr/000s/tr062levels
8205 Endosulfan: Target Organs and Levels of Evidence for TR-062 Bioassay of Endosulfan for Possible Carcinogenicity (CASRN 115-29-7) Chemical (Study Title) CASRN Peer Review Date ...
-
Abstract for TR-62 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr062
2abs Abstract for TR-62 Bioassay of Endosulfan for Possible Carcinogenicity CASRN: 115-29-7 Chemical Formula: C9H6Cl6O3S Molecular Weight: 406.9274 Synonyms/Common Names: ...
-
Abstract for TR-8 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr008
Chlordane is a member of the cyclodiene group of chlorinated insecticides, which includes aldrin, dieldrin, endrin, heptachlor, and endosulfan. It was introduced in 1945 and was ...
-
Abstract for TR-12 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr012
group, which includes aldrin (CAS No. 309-00-2), dieldrin (CAS No. 60-57-1), chlordane (CAS No. 57-74-9), heptachlor (CAS No. 76-44-8), and endosulfan (CAS No. 115-29-7). ...
-
RoC Profile: Chlorendic Acid; 15th RoC 2021 124KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chlorendicacid.pdf
insecticides such as heptachlor, chlordane, endosulfan, endrin, and dieldrin (NTP 1987). ... of numerous pesticides, including endosulfan, chlordane, heptachlor, aldrin, ...
-
Validation of In Vitro Cytotoxicity Test Methods: Test Chemicals 188KB
https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invitrocyto/ivcytodocs/valstdchm.pdf
SERVICE INC. PS-365 99 Disulfoton 298-04-4 274.42 CHEM SERVICE INC. PS-652 99.4 Endosulfan 115-29-7 406.91 CHEM SERVICE INC. PS-81 99.5 Epinephrine bitartrate 51-42-3 333.30 ...
-
TR-026: Nitrofen (CASRN 1836-75-5) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr026.pdf
... The nitrofen-treated and control rats were housed in the same room with rats treated with trifluralin (1582-09-8), dioxathion (78- 34-2), dicofol (115-32-2), endosulfan (115-29-7), ...
-
TOWARD VALIDATION OF A HUMAN IN... 1.1MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/egnashposter-2014-wc.pdf
... TER 14 Diquat dibromide Environmental TER 0.1 Glycerol Environmental NON 300 Endosulfan Environmental TER 22 Hexazinone Environmental NON 300 Fluazinam Environmental TER 10 ...
-
Application of CATMoS to Ecological Risk Assessment 2.4MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2021/ppt/2021_sacatm_s2b-1_mansouri_v3_508.pdf
... .!.J Acetaminophen 103-90-2 Endosu lfan 115-29-7 3.Phenylprop.2-enal 104-55-2 Acrolein ... 104-55-2 78 -70- 6 103-90-2 101-02 -a 115-29-7 Add chemicals w ith identi ca l QSAR st ...
-
TR-304: Chlorendic Acid (CASRN 115-28-6) in F344/N Rats and B6C3F1Mice... 14.6MB
https://ntp.niehs.nih.gov/go/tr304
... and chlorendic anhydride are used pri- endosulfan, endrin, and dieldrin) (Murphy, marily ... (Cochrane and Forbes, 1974) and endosulfan (Martens, 1972); it could therefore ...
-
Application of In Vitro to In Vivo Extrapolation (IVIVE) to Inform... 2.9MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot22/poster/mumtaz-sot2022.pdf
... - 15.7 ethion 0.002 0.06 0.014 - 48.8 4,6-dinitro-o-cresol 0.004 0.4 0.030 - 8.8 endosulfan 0.007 0.7 0.2 - 4.8 guthion (azinphos-methyl) 0.01 1 0.2 - 277.5 chlordecone 0.01 1 ...
-
Protocol: Evidence Map of Inflammation-Based Atherosclerosis... 643KB
https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosis_supplementaljuly2023_508.pdf
... OR Endocrine-disruptors[mh] OR endosulfan[tiab] OR endrin[tiab] OR ... OR Endocrine-disrupt* OR endosulfan OR endrin OR Environmental-agent* OR ...
-
TR-147: Mexacarbate (CASRN 315-18-4) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr147.pdf
... in the same room with other rats receiving diets containing dioxathion (78-34-2); dicofol (115-32-2); nitrofen (1836-75-5); endosulfan (115-29-7); and triflu- ralin (1582-09-8). ...
-
Comparison of devTOX quickPredict Assay With Other Methods 1.0MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/comparisonspreadsheet-508.pdf
... DT (Weak, 3) NON (4) NON NON D-Penicillamine 13.4 N/A N/A D DT DT (1) DT (4) n.d. NON (4) NON (3) NON (4) DT NON Endosulfan N/A N/A N/A n.d. DT n.d. DT (6) NON (6) DT (5,14) n.d. ...
-
TR-034: Trifluralin (CASRN 1582-09-8) 3.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr034.pdf
... in the same * room with other rats receiving diets treated with dioxathion (78-34- 2), dicofol (115-32-2), nitrofen (1836-75-5), endosulfan (115-29-7), and mexacarbate (315-18-4). ...
-
TR-075: Chlorobenzilate (CASRN 510-15-6) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr075.pdf
... other rats receiving diets containing trifluralin (1582-09-8); dioxathion (78-34-2); dicofol (115-32-2); nitrofen (1836-75-5); endosulfan (115-29-7); and mexa- carbate (315-18-4). ...
-
TR-091: Clonitralid (CASRN 1420-04-8) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr091.pdf
... dioxathion (78-34-2); mexacarbate (315-18-4); pentachloronitrobenzene (82-68-8); amitrole (61-82-5); nitrofen (1836-75-5); endosulfan (115-29-7); and triflur- alin (1582-09-8). ...
-
TR-115: Sulfallate (CASRN 95-06-7) 3.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr115.pdf
... other rats receiving diets containing trifluralin (1582-09-8); dioxathion (78-34-2); dicofol (115-32-2); nitrofen (1836-75-5); endosulfan (115-29-7); and mexacarbate (315-18-4). ...
-
TR-125: Dioxathion (CASRN 78-34-2) 1.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr125.pdf
... Treated and control rats were housed in the same room with other rats receiving diets containing trifluralin (1582-09-8); endosulfan (115-29-7); dicofol (115-32-2); nitrofen ...
-
TR-008: Chlordane (CASRN 57-74-9) 3.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr008.pdf
... in the Diet 41 xi I. INTRODUCTION Chlordane is a member of the cyclodiene group of chlorinated insecticides, which includes aldrin, dieldrin, endrin, heptachlor, and endosulfan. ...
-
TR-012: Endrin (CASRN 72-20-8) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr012.pdf
... C I of the cyclodiene group, which includes aldrin (CAS 309-00-2), dieldrin (CAS 60-57-1), chlordane (CAS 57-74-9), heptachlor (CAS 76-44-8), and endosulfan (CAS 115-29-7). ...
-
Comparison of the Stemina devTOX quickPredict system with other... 2.1MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2018-09961/palmer-stemina-spreadsheet.pdf
... D-Penicillamine DT D DT (1) DT (4) n.d. NON (4) NON (3) NON (4) 1.16 NON NON 13.4 N/A N/A Exposure (Cmax) Human Endosulfan DT n.d. n.d. DT (6) NON (6) DT (5,14) n.d. n.d. 0.67 DT ...
-
Minutes: BSC; April 17, 1996 335KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1996/april/19960417_bsc_508.pdf
... estrogens - endosulfan, methoxychlor, and p-nonylphenol - an anti- androgen, vinclozolin, and a naturally occurring plant estrogen, genistein. Endosulfan and vinclozolin ...
-
TR-035: Methoxychlor (CASRN 72-43-5) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr035.pdf
... (82-68-8), amitrole (61-82-5), acetylaminofluorene (53-96-3), clonitralid (1420-04-8), nitrofen (1836-75-5), endosulfan (115-29-7), mexacarbate (315-18-4), and safrole (94-59-7). ...
-
TR-061: Pentachloronitrobenzene (CASRN 82-68-8) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr061.pdf
... (510-15-6); clonitralid (1420-04-8); nitrofen (1836-75-5); endosulfan (115-29-7); mexacarbate (315-18-4); amitrole (61-82-5); acetylaminofluorene (53-96-3); and safrole (94-59-7). ...
-
TR-090: Dicofol (CASRN 115-32-2) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr090.pdf
... housed in the same room with rats receiving diets containing dioxathion (78-34-2); mexacarbate (315-18-4); nitrofen (1836-75-5); endosulfan (115-29-7); and trifluralin (1582-09-8). ...
-
ICCVAM Background Review Document (Vol 1): In Vitro Cytotoxicity... 16.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol1_nov2006.pdf
... Organic compound; Nitrile; Ester; Ether Endosulfan 18 * TESS, EPA, NTP Pesticide ... 10-64 13-81.5 0.127 0.050-0.32 6.3 5 20 Endosulfan 28 NC 18-43 0.068 NC 2.4 2 18 8 Digoxin ...
-
ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... 0.47-500 Disulfoton 298-04-4 99.4 Chem Service, Inc. 8.0 2.4-2500 7.8 2.4-2500 Endosulfan 115-29-7 99.5 Chem Service, Inc. 8.3 0.1-100 7.8 0.67-50 Epinephrine bitartrate 51-42-3 > ...
-
DART-07: Prenatal Development Studies of 2-((1-(4-Phenoxyphenoxy... 1.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/dart/dart07_508.pdf
... 1 Methyl Parathion b <0.02 1 Ethyl Parathion b <0.02 1 Malathion 0.11 1 Endosulfan I b <0.01 1 Endosulfan II b <0.01 1 Endosulfane Sulfate b <0.03 1 All samples were irradiated. ...
-
TR-131: Bioassays of DDT, TDE, and p,p'-DDE (CASRN 50-29-3, CASRN... 7.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr131.pdf
... nitrobenzene (82-68-8); clonitralid (1420-04-8); nitrofen (1836-75-5); endosulfan (115-29-7); trifluralin (1582-09-8); amitrole (61-82-5); acetylaminofluorene (53-96-3); ...
-
TR-437: Hexachlorocyclopentadiene (CASRN 77-47-4) in F344/N Rats... 15.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr437.pdf
... aldrin, dieldrin, heptachlor, mirex, endosulfan, and pentac) (Bell et al., 1979) and ... 17 Malathion 0.14 2 0.12 0.05 - 0.35 17 Endosulfan I <0.01 17 Endosulfan I1 <0.01 17 ...
-
XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... Chemical a-Endosulfan 959-98-8 Pesticide environmental contaminant 4.00E+07 - 1.95E+04 1.00E+02 - 4.88E-02 2.46E-04 - 1.20E-07 > 98% Sigma Powder b-Endosulfan 33213-65-9 ...
-
TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf
... Trithion (a) Diazinon (a) Methyl parathion (a) Ethyl parathion (a) Malathion (1) Endosulfan I (m) Endosulfan II (m) Endosulfan sulfate (m) Mean k S t a n d a r d Deviation 0.50 f ...
-
TOX-103: Select Ionic Liquids (1-Ethyl-3-Methylimidazolium Chloride... 4.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox103_508.pdf
... 1 Methyl Parathion a <0.02 1 Ethyl Parathion a <0.02 1 Malathion 0.0324 1 Endosulfan I a <0.01 1 Endosulfan II a <0.01 1 Endosulfane Sulfate a <0.03 1 All samples were irradiated. ...
-
Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... Chemical a-Endosulfan 959-98-8 Pesticide environmental contaminant 4.00E+07 - 1.95E+04 1.00E+02 - 4.88E-02 2.46E-04 - 1.20E-07 > 98% Sigma Powder b-Endosulfan 33213-65-9 ...
-
NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Evidence P Clear Evidence P Clear Evidence P Clear Evidence TR-062 01/18/78 Endosulfan 115-29-7 IS Inadequate Experiment N No Evidence IS Inadequate Experiment N No Evidence ...
-
TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf
... - 4 Ethyl Parathion a <0.02 - 4 Malathion 0.040 ± 0.039 0.02-0.10 4 Endosulfan I a <0.01 - 4 Endosulfan II a <0.01 - 4 Endosulfane Sulfate a <0.03 - 4 All samples were irradiated. ...
-
TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox102_508.pdf
... 1 Methyl Parathion a <0.02 1 Ethyl Parathion a <0.02 1 Malathion 0.043 1 Endosulfan I a <0.01 1 Endosulfan II a <0.01 1 Endosulfane Sulfate a <0.03 1 All samples were irradiated. ...
-
TR-600: Di-n-butyl Phthalate Administered in Feed to Sprague... 3.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf
... 2 Ethyl Parathion a <0.02 - 2 Malathion 0.153 ± 0.002 0.151-0.154 2 Endosulfan I a <0.01 - 2 Endosulfan II a <0.01 - 2 Endosulfane Sulfate a <0.03 - 2 All samples were irradiated. ...
-
TOX-98: Acetoin (CASRN 513-86-0) and 2,3-Pentanedione (CASRN... 3.0MB
https://ntp.niehs.nih.gov/go/tox098
... 8 Ethyl Parathion a <0.02 - 8 Malathion 0.073 ± 0.078 0.02-0.234 8 Endosulfan I a <0.01 - 8 Endosulfan II a <0.01 - 8 Endosulfane Sulfate a <0.03 - 8 All samples were irradiated. ...
-
TR-334: 2-Amino-5-Nitrophenol (CASRN 121-88-0) in F344/N Rats... 9.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr334.pdf
... Trithion (a) Diazinon (a) Methyl parathion (a) Ethyl parathion (a) Malathion (p) Endosulfan I (q) Endosulfan II (q) Endosulfan sulfate (q) Mean * Standard Deviation 0.46 f 0.10 c o ...
-
TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf
... Trithion ( a ) Diazinon (a) Methyl parathion (a) Ethyl parathion (a) Malathion (p) Endosulfan I b,q) Endosulfan II (a,q) Endosulfan sulfate (a,q) Mean 5 Standard Deviation 0.46 f ...
-
TR-375: Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32... 20.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr375.pdf
... 25 Ethylparathion(a) <0.02 25 Malathion (l) 0.10 ± 0.10 <0.05-0.45 25 Endosulfan I (m) <0.01 23 Endosulfan II (ml <0.01 23 Endosulfan sulfate (ml <0.03 23 Vinyl Toluene (mixed ...
-
Draft TR-600: Di-n-butyl Phthalate (CASRN 84-74-2) Administered... 2.0MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr600_508.pdf
... 2 Ethyl Parathion a <0.02 - 2 Malathion 0.153 ± 0.002 0.151-0.154 2 Endosulfan I a <0.01 - 2 Endosulfan II a <0.01 - 2 Endosulfane Sulfate a <0.03 - 2 All samples were irradiated. ...
-
TR-317: Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats... 10.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr317.pdf
... Trithion (a) Diazinon (a,o) Methyl parathion (a) Ethyl parathion (a) Malathion (p) Endosulfan I (a.q) Endosulfan II (a,q) Endosulfan sulfate (a,q) Mean t Standard Dewiation 0.49 f ...
-
TR-329: 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr329.pdf
... Trithion (a) Diazinon (a) Methyl parathion (a) Ethyl parathion (a) Malathion (k) Endosulfan 10) Endosulfan II (1) Endosulfan sulfate (1) Mean F Standard Deviation 0.53 f 0.13 co.1 ...
-
TR-340: Iodinated Glycerol (Organidin) (CASRN 5634-39-9) in F344... 9.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr340.pdf
... Trithion (a) Diazinon (a) Methyl parathion (a) Ethyl parathion (a) Malathion (q) Endosulfan I (r) Endosulfan II (r) Endosulfan sulfate (r) 0.45 f 0.11 <0.1 0.95 f 0.78 <0.05 0.28 f ...
-
TR-345: Roxarsone (CASRN 121-19-7) in F344/N Rats and B6C3F1... 25.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr345.pdf
... 57 590 ± 74 840 ± 40 840 ± 93 413 ± 115
29 7 ± 32 253 ± 1 9 35 3 ± 4 1 340 ± 25 ... Malathion (q) 0.08 ± 0.05 <0.05-0.25 25 Endosulfan I (a,r) <0.01 17 Endosulfan II (a,r) ...
-
TR-348: alpha-Methyldopa Sesquihydrate (CASRN 41372-08-1) in... 10.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr348.pdf
... Trithion ( a ) Diazinon ( a ) Methyl parathion (a) Ethyl parathion (a) Malathion (p) Endosulfan I (a,q) Endosulfan II (a,q) Endosulfan sulfate (a,q) Mean _+ S t a n d a r d ...