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Search suggestions for "118-74-1".

  1. CEBS Data Related to Hexachlorobenzene (118-74-1) https://cebs.niehs.nih.gov/cebs/test_article/118-74-1
  2. Report on Carcinogens Hexachlorobenzene https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/hexachlorobenzene.pdf


72 results found for "118-74-1".

  1. TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox077_508.pdf

    STudieS of hexachloRobeNzeNe (caSRN 118-74-1) admiNiSTeRed by GavaGe To female SPRaGue dawley (hSd:SPRaGue dawley ® Sd ® ) RaTS NTP TOX 77 MARCH 2021 NTP Technical Report on the ...

  2. RoC Profile: Hexachlorobenzene; 15th RoC 2021 155KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/hexachlorobenzene.pdf

    Hexachlorobenzene CAS No. 118-74-1 Reasonably anticipated to be a human carcinogen First listed in the Third Annual Report on Carcinogens (1983) Cl Cl Cl Cl Cl Cl Carcinogenicity ...

  3. Abstract for TOX-77 69KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox077

    Abstract for TOX-77 Toxicity Studies of Hexachlorobenzene Administered by Gavage to Female Sprague Dawley (Hsd:Sprague Dawley SD) Rats CASRN: 118-74-1 Chemical Formula: C6Cl6 ...

  4. TOX-6: Pentachlorobenzene (CASRN 608-93-5) 3.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox006.pdf

    ... compounds such as lindane and hexachlorobenzene (Villaneuva et al., 1974; USEPA, ... It is also known to be an im- purity of hexachlorobenzene and pentachloroni- trobenzene ...

  5. RoC Monograph: Pentachlorophenol and By-products of Its Synthesis... 2.9MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/pentachlorophenol_508.pdf

    ... are higher-chlorinated dioxins and furans, polychlorinated phenols, and hexachlorobenzene. ... dioxins and furans, polychlorinated phenols, hexachlorobenzene and other by- products. ...

  6. TOX-7: 1,2,4,5-Tetrachlorobenzene (CASRN 95-94-3) 4.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox007.pdf

    ... organochlorine compounds, such as hexachlorobenzene or lindane in rats, pheasants, or ... only halo- genated benzene besides hexachlorobenzene that enhanced production of ...

  7. TR-325: Pentachloronitrobenzene (CASRN 82-68-8) in B6C3F1Mice... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr325.pdf

    ... for the re- duction of the percentage of hexachlorobenzene to 0.1%. Available studies indicate that the im- purity hexachlorobenzene is likely to be respon- sible for the ...

  8. Tooth, Incisor - Degeneration - Nonneoplastic Lesion Atlas 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/tooth/Incisor-Degeneration

    References: Long PH, Herbert RA, Nyska A. 2004. Hexachlorobenzene-induced incisor degeneration in Sprague-Dawley rats. Toxicol Pathol 32:35-40. Abstract: https://...

  9. TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB

    https://ntp.niehs.nih.gov/go/tr349

    ... and Use methods: direct chlorination of phenols or hy- drolysis of hexachlorobenzene. ... relatively large quan- tities of hexachlorobenzene, chlorophenoxyphe- nols, CDDs, and ...

  10. Tooth, Incisor - Degeneration 385KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/tooth/indegen/tooth-incisor-degeneration_508.pdf

    References Long PH, Herbert RA, Nyska A. 2004. Hexachlorobenzene-induced incisor degeneration in Sprague- Dawley rats. Toxicol Pathol 32:35-40. Abstract: http://...

  11. Protocol: Evaluation of Human Cancer Studies on Exposure to Pentachlor... 363KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/pcphumanstudies20130815_508.pdf

    ...chlorodibenzo-p-dioxins, octachlorodibenzo-p-dioxins), higher chlorinated furans hexachlorobenzene and other higher chlorinated phenols (tetrachlorophenol, trichlorophenol). ...

  12. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... 117-79-3 see 2-Aminoanthraquinone 117-81-7 see Di(2-ethylhexyl) Phthalate 118-74-1 see Hexachlorobenzene 119-90-4 (3,3'-dimethoxybenzidine) see 3,3'-Dimethoxybenzidine and Dyes ...

  13. TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf

    ... penta- chloronitrobenzene, sodium pentachlorophenate,.and hexachlorobenzene (Figure 1). ... HEXACHLOROBENZENE FIGURE 1 Chlorinated Aromatic Compounds Structurally Related to ...

  14. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... Ethyl Methanesulfonate Furan Glass Wool Fibers (Inhalable), Certain Glycidol Hexachlorobenzene Hexachloroethane Hexamethylphosphoramide Hydrazine and Hydrazine Sulfate ...

  15. Short-Term Toxicity Reports 224KB

    https://ntp.niehs.nih.gov/publications/reports/tox

    ... Mice 2018 Short-Term Toxicity TOX-77 PDF (2.19 MB) Toxicity Studies of Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage to Female Sprague Dawley (Hsd:Sprague Dawley SD) ...

  16. Draft RoC Monograph for Pentachlorophenol: Literature Search... 2.0MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/pcpliteraturesearch20130815_508.pdf

    ... 6c) Pentachlorobenzene Table 6d) Hexachlorobenzene Table 6e) Tetrachlorodibenzodioxin ... General Sources Checklist for: Hexachlorobenzene Source Name of document 1) NTP technical ...

  17. TR-255: 1,2-Dichlorobenzene (o-Dichlorobenzene) (CASRN 95-50... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr255.pdf

    ... Therefore, although hexachlorobenzene is clearly porphyrogenic, there is less evidence ... Although there is clear- cut evidence that hexachlorobenzene produces porphyria (Cam and ...

  18. TR-319: 1,4-Dichlorobenzene (CASRN 106-46-7) in F344/N Rats and... 17.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr319.pdf

    ... Later work showed that, unlike hexachlorobenzene, which produces porphyria in female rats ... In comparison, hexachlorobenzene adni.inistered in the diet at 300 ppm to female ...

  19. Application of In Vitro to In Vivo Extrapolation (IVIVE) to Inform... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot22/poster/mumtaz-sot2022.pdf

    ... pentachlorophenol 0.005 5 0.1 - 21.1 di-n-butyl phthalate 0.5 50 1.1 - 148.2 hexachlorobenzene 0.008 2.4 141.1 ethylene glycol 0.8 80 9.2 1,4-dioxane 5 500 12.6 Neurotoxicity ...

  20. RoC Concept: Pentachlorophenol 299KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/concepts/pcp_concdocroc8-30-12_508.pdf

    ... An alternative production method used in other countries is the hydrolysis of hexachlorobenzene, which can form 2,3,7,8-TCDD (reviewed by IARC 1991). 3. Overview of the ...

  21. RoC Profile: Mirex; 15th RoC 2021 138KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/mirex.pdf

    ... Bloom MS, Vena JE, Swanson MK, Moysich KB, Olson JR. 2005. Profiles of ortho-polychlorinated biphenyl congeners, dichlorodiphenyldichloroethylene, hexachlorobenzene, and mirex ...

  22. RoC Profile: Pentachlorophenol and By-products of Its Synthesis... 220KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/pentachlorophenol.pdf

    ... Another process, alkaline hydrolysis of hexachlorobenzene (HCB), might have been used in ... rise to penta- chlorophenol include hexachlorobenzene, penta chlorobenzene, pen- ...

  23. Peer Review Report: RoC Peer Review; Dec. 12-13, 2013 287KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2013/december/peerreviewrpt20131213_508.pdf

    ... tri- and tetra-chlorinated phenols, hexachlorobenzene, and dioxins and furans (primarily ... higher chlorinated phenoxyphenols, hexachlorobenzene, dioxin-like chemicals, and furans. ...

  24. TR-483: Pentachlorophenol (CASRN 87-86-5) in F344/N Rats (Feed... 7.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr483.pdf

    ... In addition, a number of other chemicals such as hexachlorobenzene, pentachlorobenzene, ... (6.5%), octachlorodibenzo- p-dioxin (2%), and hexachlorobenzene (10 ppm). ...

  25. TOX-28: Tetrachlorophthalic Anhydride (CASRN 117-08-8) 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox028.pdf

    ... Supporting factors were the relatively large production volume and structural similarity to carcinogenic aromatic halides such as hexachlorobenzene and 2,4,6-trichlorophenol (NCI, ...

  26. TR-538: Methyl Isobutyl Ketone (CASRN 108-10-1) in F344/N Rats... 13.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr538.pdf

    ... administered after hexachlorobenzene. However, the simultaneous admin- istration of methyl isobutyl ketone and hexachloro- benzene reduced the hexachlorobenzene-induced hepatic ...

  27. NTP Monograph on Health Effects of Low-Level Lead Appendices... 6.8MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/appendicesathrue_final_508.pdf

    ... aldrin, β- HCH, DDE, DDT, Mirex, Hexachlorobenzene, Chlordane, Cis- Nonachlor, Trans- ... (GSTM1); Hb - hemoglobin; HCB - hexachlorobenzene; γ-HCB- hexachlorocyclobenzene; Hg ...

  28. TR-392: Chlorinated Water (CASRNs. 7782-50-5 and 7681-52-9) and... 75.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr392.pdf

    ... chloroethane and hexachlorobenzene, were not present at concentrations greater than 0.01%. ... Gas chromatography indicated that hexachloroethane and hexachlorobenzene, possible ...

  29. TOX-1: Hexachloro-1,3-butadiene(CASRN 87-68-3) 415KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox001.pdf

    ... D. (1971) Review of the Toxicity of Hexachlorobenzene and Hexa- chlorobutadiene. ... Industrial Processing Data, Task I-Hexachlorobenzene and Hexachlo- robutadiene Pollution ...

  30. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf

    ... 142.29 1-Heptene 592-76-7 98.19 2-Hexanone (MBK) 591-78-6 100.16 Hexachlorobenzene 118-74-1 284.78 Hexachlorobutadiene 87-68-3 260.76 Hexachlorocyclopentadiene 77-47-4 ...

  31. TR-311: Tetrachloroethylene (Perchloroethylene) (CASRN 127-18... 13.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr311.pdf

    ... At 700" C in contact with active carbon, it decomposes to hexachloroethane and hexachlorobenzene. Reactivity Oxidized by strong oxidizing agents (sulfuric and nitric acids, sulfur ...

  32. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... 117-79-3 see 2-Aminoanthraquinone 117-81-7 see Di(2-ethylhexyl) Phthalate 118-74-1 see Hexachlorobenzene 119-90-4 (3,3'-dimethoxybenzidine) see 3,3'-Dimethoxybenzidine and Dyes ...

  33. TR-061: Pentachloronitrobenzene (CASRN 82-68-8) 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr061.pdf

    ... Mutation Research 11: 247-248, 1971. Courtney, K.D., M.F. Copeland, and A. Robbins, "The Effects of Penta- chloronitrobenzene, Hexachlorobenzene and Related Compounds on Fetal ...

  34. TR-521: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) (CASRN 1746... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr521.pdf

    ... chlorophenols, chlorodiphenyl ether herbicides [e.g., 1,3,4-trichloro-2-(4-nitrophenoxy)ben- zene], hexachlorobenzene, pulp bleaching, and the man- ufacture of dyes and pigments. ...

  35. TOX-103: Select Ionic Liquids (1-Ethyl-3-Methylimidazolium Chloride... 4.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox103_508.pdf

    ...hlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl. a ...hlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl. a ...

  36. TR-244: Polybrominated Biphenyl Mixture (Firemaster FF-1) in... 8.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr244.pdf

    ... the porphyrogenic action of hexachlorobenzene in rats (San Martin de Viale et al., 1970). ... accidental consumption of hexachlorobenzene in Turkey in 1956 (Ockner and Schmid, 1961). ...

  37. TOX-65: 3,3',4,4'-Tetrachloroazobenzene 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox065.pdf

    ... Hexachlorobenzene, a compound with dioxin-like and nondioxin-like activities, resulted in ... Autoimmune effects of hexachlorobenzene in the rat. Toxicol. Appl. Pharmacol. 122, ...

  38. TOX-66: 3,3',4,4'-Tetrachloroazoxybenzene 3.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox066.pdf

    ... Hexachlorobenzene, a compound with dioxin-like and nondioxin-like activities, resulted in ... Autoimmune effects of hexachlorobenzene in the rat. Toxicol. Appl. Pharmacol. 122, ...

  39. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... > 98% Sigma liquid Hexachlobenzene 118-74-1 Organochlorine environmental contaminant ... ND Non-Active N/A N/A Hexachlobenzene 118-74-1 X X X X X Non-Active ND Non-Active N/A ...

  40. DART-07: Prenatal Development Studies of 2-((1-(4-Phenoxyphenoxy... 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/dart/dart07_508.pdf

    ...hlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl. a ...hlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl. a ...

  41. Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf

    ... > 98% Sigma liquid Hexachlobenzene 118-74-1 Organochlorine environmental contaminant ... ND Non-Active N/A N/A Hexachlobenzene 118-74-1 X X X X X Non-Active ND Non-Active N/A ...

  42. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Mice 2018 Short-Term Toxicity TOX-77 PDF (2.19 MB) Toxicity Studies of Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage to Female Sprague Dawley (Hsd:Sprague Dawley SD) ...

  43. NTP Monograph on Health Effects of Low-Level Lead Appendix A... 2.5MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixa_final_508.pdf

    ... DDE, DDT, Mirex, Hexachlorobenzene, Chlordane, Cis- Nonachlor, Trans- Nonachlor, Oxychlordane, and Hg Model included weight and child PCB153 Model F =4.41, p< 0.01; R 2 = 0.14 Alt. ...

  44. NTP Monograph on Health Effects of Low-Level Lead Appendix B... 873KB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixb_final_508.pdf

    ... assay; glutathione S transferase M1 gene (GSTM1); Hb - hemoglobin; HCB - hexachlorobenzene; γ-HCB- hexachlorocyclobenzene; Hg - mercury; HLA-DR - human leukocyte-assisted ...

  45. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Mice 2018 Short-Term Toxicity TOX-77 PDF (2.19 MB) Toxicity Studies of Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage to Female Sprague Dawley (Hsd:Sprague Dawley SD) ...

  46. TR-437: Hexachlorocyclopentadiene (CASRN 77-47-4) in F344/N Rats... 15.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr437.pdf

    ... preparation o f hexachlorocyclopentadiene include octachlorocyclopentadiene~exachloro-1,3-butadiene, tetrachloroethane, hexachlorobenzene, and penta- chlorobenzene(BUA, 1 9 8 8 ) . ...

  47. TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox102_508.pdf

    ...hlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl. a ...hlorodiphenyltrichloroethane; HCB = hexachlorobenzene; MPN = most probable number; PCB = ...

  48. DART-01: Prenatal Development Studies of Tris(chloropropyl) Phosphate... 937KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart01_508.pdf

    ... = dichlorodiphenyldichloroethane; DDT = dichlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl; PCB = polychlorinated biphenyl. a All samples ...

  49. DART-02: Prenatal Development Studies of 4-Methylcyclohexanemethanol... 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart02_508.pdf

    ... = dichlorodiphenyldichloroethane; DDT = dichlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl; PCB = polychlorinated biphenyl. a All samples ...

  50. DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf

    ... = dichlorodiphenyldichloroethane; DDT = dichlorodiphenyltrichloroethane; HCB = hexachlorobenzene; PCB = polychlorinated biphenyl. a All samples were irradiated. b For values less ...

 
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