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68 results found for "119-61-9".
  1. TR-533: Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1Mice... 10.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr533.pdf

    BENZOPHENONE (CAS NO. 119-61-9) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 February 2006 NTP TR 533 ...

  2. TOX-61: Benzophenone 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox061.pdf

    National Toxicology Program Toxicity Report Series Number 61 NTP Technical Report on the Toxicity Studies of Benzophenone (CAS No. 119-61-9) Administered in Feed to F344/N Rats and ...

  3. Abstract for TR-533 72KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr533

    Abstract for TR-533 Toxicology and Carcinogenesis Studies of Benzophenone in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 119-61-9 Chemical Formula: C13H10O Molecular Weight: ...

  4. Abstract for TOX-61 63KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox061

    1abs Abstract for TOX-61 Toxicity Studies of Benzophenone Administered in Feed to F344/N Rats and B6C3F1 Mice CASRN: 119-61-9 Chemical Formula: C12H10O Molecular Weight: 182.22 ...

  5. Abstract for TER98005 62KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter98005

    Developmental Toxicity Evaluation for Benzophenone Administered by Gavage to Sprague Dawley (CD) Rats on Gestational Days 6 Through 19 CASRN: 119-61-9 Chemical Formula: C13H10O ...

  6. Abstract for TER99001 62KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter99001

    Developmental Toxicity Evaluation for Benzophenone Administered by Gavage To New Zealand White Rabbits on Gestational Days 6 Through 29 CASRN: 119-61-9 Chemical Formula: C13H10O ...

  7. Target Organs and Levels of Evidence for TR-533 60KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr533levels

    Target Organs and Levels of Evidence for TR-533 Toxicology and Carcinogenesis Studies of Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical (Study ...

  8. Comment: Draft Report 05 Dated March 21, 2021; J.C. DiNardo;... 243KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/publiccomm/dinardo_oxybenzone20210928_trprp_508.pdf

    (2H4MBP), also known as oxybenzone and benzophenone-3, is approved by the U.S. Food and ... For example: in the Scientific Committee on Consumer Safety (SCCS) opinion on benzophenone...

  9. Abstract for TOX-21 64KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox021

    CASRN: 131-57-7 Chemical Formula: C14H12O3 Molecular Weight: 228.26 Synonyms/Common Names: Oxybenzone; 4-methoxy-2-hydroxy-benzophenone; (2-hydroxy-4-methoxyphenyl)phenyl-methanone...

  10. TOX-21: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) 21.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox021.pdf

    ... Oxybenzone; 4-Methoxy-2- hydroxy-benzophenone; Cyasorb UV; Uvinul M 40; ... studies of 2-hydroxy-4-methoxy- benzophenone (HMB) by reviewing the natural ...

  11. Oviduct - Mesonephric Duct Remnant - Nonneoplastic Lesion Atlas 287KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/oviduct/MesonephricDuctRemnant

    National Toxicology Program. 2006. NTP TR-533. Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...

  12. Ovary - Infiltration Cellular - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/InfiltrationCellular

    National Toxicology Program. 2006. NTP TR-533. Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...

  13. Minutes: BSC TR; Nov. 21, 1991 728KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1991/minutesbsctrrs19911121_508.pdf

    68-12-2 Inhalation 2-Hydroxy-4-Methoxy-Benzophenone 131-57-7 Dermal/Feed o-,m-, and ... and as a representative benzophenone derivative used as a UV screen and UV stabilizer. ...

  14. Historical Controls: All Routes and Vehicles for Mice; Studies... 255KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/m_hcrpt_allrte2006_508.pdf

    09/14/99 730 50(1) 44(717) 46.0 Benzophenone Battelle Columbus Laboratory 055611104 ... 09/13/99 729 50(5) 40(706) 46.2 Benzophenone Battelle Columbus Laboratory 055611104 ...

  15. Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf

    Battelle Columbus Laboratory 058813803 08/16/99 729 50(3) 22(681) 501.7 Benzophenone ... Battelle Columbus Laboratory 058813803 08/17/99 729 50(5) 32(688) 348.7 Benzophenone ...

  16. Historical Controls: All Routes and Vehicles for Mice; Studies... 317KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20070300_508.pdf

    09/14/99 730 50(1) 44(717) 46.0 Benzophenone Southern Research Institute 059902704 ... 09/13/99 729 50(5) 40(706) 46.2 Benzophenone Southern Research Institute 059902704 ...

  17. Historical Controls: All Routes and Vehicles for Mice; Studies... 211KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20071000_508.pdf

    Battelle Columbus Laboratory 058813804 09/14/99 730 50(1) 44(717) 46.0 Benzophenone ... Battelle Columbus Laboratory 058813804 09/13/99 729 50(5) 40(706) 46.2 Benzophenone ...

  18. Historical Controls: All Routes and Vehicles for Rats; Studies... 252KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20070300_508.pdf

    Battelle Columbus Laboratory 058813803 08/16/99 729 50(3) 22(681) 501.7 Benzophenone ... Battelle Columbus Laboratory 058813803 08/17/99 729 50(5) 32(688) 348.7 Benzophenone ...

  19. Historical Controls: All Routes and Vehicles for Rats; Studies... 225KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20071000_508.pdf

    Battelle Columbus Laboratory 058813803 08/16/99 729 50(3) 22(681) 501.7 Benzophenone ... Battelle Columbus Laboratory 058813803 08/17/99 729 50(5) 32(688) 348.7 Benzophenone ...

  20. Historical Controls: All Route and Vehicles for Rats; Studies... 162KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2008/r_hcrtp_allrte_20081100.pdf

    08/16/99 729 50 (3) 22(681) 501.7 Benzophenone Battelle Columbus Laboratory 059902805 ... 08/17/99 729 50 (5) 32(688) 348.7 Benzophenone Battelle Columbus Laboratory 059902805 ...

  21. Ovary - Infiltration Cellular 286KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/ovary/infilt/ovary-infiltration-cellular-pdf-508.pdf

    Reference: National Toxicology Program. 2006. NTP TR-533. Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F 1 Mice (Feed Studies). ...

  22. Draft DART-05: Modified One-Generation Study of 2-Hydroxy-4-methoxyben... 3.3MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/dart05_508.pdf

    ... also known as oxybenzone and 2 benzophenone-3, is approved by the U.S. Food and ... Expected estrogenic responses were observed in the 15 EE group. 16 Synonyms: Benzophenone-...

  23. DART-05: Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophen... 6.0MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart05_508.pdf

    ... (2H4MBP), also known as oxybenzone and benzophenone-3, is approved by the U.S. Food and ... Expected estrogenic responses were observed in the EE group. Synonyms: benzophenone-3; ...

  24. TR-597: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered... 3.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr597_508.pdf

    ... with exposure to 2H4MBP. Synonyms: Benzophenone-3; (2-hydroxy-4-methoxyphenyl)-phenylm... ; Molecular Weight: 228.25) Synonyms: Benzophenone-3; (2-hydroxy-4-methoxyphenyl)-phenylm...

  25. Ovary - Mineral - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/Mineral

    National Toxicology Program. 2006. NTP TR-533. Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...

  26. Oviduct - Mesonephric Duct Remnant 288KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/oviduct/mdremn/oviduct-mesonephric-duct-remnant-pdf-508.pdf

    Program. 2006. NTP TR-533. Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F 1 Mice (Feed Studies). NTP, Research Triangle ...

  27. UV Filters 75KB

    https://ntp.niehs.nih.gov/whatwestudy/topics/uvfilters

    Oxybenzone Benzophenone-3 Type of filter: UVB, UVA Two-year chronic toxicity studies: Completed Findings: In rats, NTP found uncertain evidence of the toxicity and carcinogenicity ...

  28. Ovary - Mineral 306KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/ovary/mineral/ovary-mineral-pdf-508.pdf

    .../go/6018 National Toxicology Program. 2006. NTP TR-533. Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F 1 Mice (Feed Studies). ...

  29. Presentation: Using Adverse Outcome Pathway Analysis to Identify... 2.2MB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/paul-508.pdf

    ... NIS T4, T3 Propylthiouracil, methimazole, Benzophenone-2, isoflavones, etc. Perchlorate, bromate, some small organics PCBs, PTU, FD&C Red No3 dye, etc. ? Figure reproduced from ...

  30. RoC Profile: Michler's Ketone; 15th RoC 2021 122KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/michlersketone.pdf

    Also known as 4,4'-(dimethylamino)benzophenone C O N N H 3 C CH 3 CH 3 CH 3 ... Part 2. Survey for residues of dialkylamino benzophenone UV-cure ink photoinitiators. Food ...

  31. Minutes: BSC; Oct. 26, 2004 769KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2004/october/bscmins2004oct26_508.pdf

    ... two water disinfection by-products (bromodichloromethane and sodium chlorate), and benzophenone. 5. Center for the Evaluation of Risk to Human Reproduction The Center for the ...

  32. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence NE No Evidence NE No Evidence EE Equivocal Evidence TR-533 12/09/04 Benzophenone 119-61-9 SE Some Evidence EE Equivocal Evidence SE Some Evidence SE Some Evidence TR-532 ...

  33. Short-Term Toxicity Reports 224KB

    https://ntp.niehs.nih.gov/publications/reports/tox

    ... Hamsters 2007 Short-Term Toxicity TOX-61 PDF (2.12 MB) Toxicity Studies of Benzophenone (CASRN 119-61-9) Administered in Feed to F344/N Rats and B6C3F1 Mice 2000 Short-Term ...

  34. Comment: Draft Report 06 Dated March 21, 2021; J.C. DiNardo;... 151KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/publiccomm/dinardo_octinoxate20210928_trprp_508.pdf

    ... Based on keyword analysis, benzophenone-3, 4-methylbenzylidene-camphor, 3- benzylidene camphor, and ethylhexyl-methoxycinnamate are the most studied OUVFs, and effects on ...

  35. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-533 PDF (10.78 MB) Toxicology and Carcinogenesis Studies of Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2006 Technical Report TR-532 ...

  36. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-533 PDF (10.78 MB) Toxicology and Carcinogenesis Studies of Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2006 Technical Report TR-532 ...

  37. Poster Abstracts: In Vitro to In Vivo Extrapolation for High... 132KB

    https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/posterabstracts-all-508.pdf

    ... and 6-propylthiouracil) to moderate (benzophenone-2 and 2- mercaptobenzothiazole) to low ... For example, benzophenone-2 and triclosan exhibited small MOE values due to slow clearance ...

  38. Minutes: BSC; Aug. 18, 2005 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2005/august/bscmins2005aug18_508.pdf

    ... on December 9, 2004. The Subcommittee reviewed reports on 3'-azido-3'thymidine, benzophenone, bromodichloromethane, 2,2',4,4',5,5'-hexachloro-biphenyl (PCB 153), a PCB mixture ...

  39. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-533 PDF (10.78 MB) Toxicology and Carcinogenesis Studies of Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2006 Long-Term ...

  40. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    ... to no longer authorize the use of benzophenone, ethyl acrylate, eugenyl methyl ether, ... Because of evidence that benzophenone causes cancer in animals, FDA also is amending the ...

  41. Public Comment: Pulegone Christie Harman; RoC; Sept. 20, 2013 126KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/harman20131018_508.pdf

    ... Toxicology 55, 327-337. Page | 9 National Toxicology Program (NTP) (2006) NTP Technical Report on the Toxicology and Carcinogenesis Studies of Benzophenone (CAS NO. 119-61-9) in ...

  42. Minutes: BSC; June 29, 2004 883KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2004/june/20040629_508.pdf

    ... mixture of 2,3,4,4',5, pentachlorobiphenyl (PCB 118) and PCB 126, sodium chlorate, benzophenone, bromodichloromethane, a transplacental azidothymidine (AZT) study, and a genistein ...

  43. TR-562: Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats... 6.4MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr562.pdf

    ... Historical Incidence: Feed Studies Benzophenone 2/50 2/50 Chromium picolinate monohydrate ... Study Incidence in Controls Historical Incidence: Feed Studies Benzophenone 10/50 Chromium ...

  44. TR-550: Cresols (CASRN 1319-77-3) in Male F344/N Rats and Female... 3.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr550.pdf

    ... National Toxicology Program (NTP) (2006). NTP Technical Report on the Toxicology and Carcinogenesis Studies of Benzophenone (CAS No. 119-61-9) in F344/N Rats and B6C3F 1 Mice (Feed ...

  45. TR-568: Photocarcinogenesis Studies of Retinoic Acid and Retinyl... 18.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr568_508.pdf

    ... octyl methoxycinnamate, avobenzone, and 4-methylbenzilidene camphor or a photostable UV-filter combination that contained octyl methoxycinnamate, benzophenone-3, and octocrylene. ...

  46. TR-535: 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr535.pdf

    ... Historical Incidence: Feed Studies Benzophenone 19/50 trans-Cinnamaldehyde 21/100 ... Historical Incidence: Feed Studies Benzophenone 14/50 2/50 16/50 trans-Cinnamaldehyde ...

  47. TR-556: Chromium Picolinate Monohydrate (CASRN 27882-76-4) in... 6.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr556.pdf

    ... Historical Incidence in Feed Controls Given NTP-2000 Diet Benzophenone 0/50 Chromium ... Historical Incidence in Feed Controls Given NTP-2000 Diet Benzophenone 3/50 Chromium ...

  48. TR-523: Diisopropylcarbodiimide (CASRN 693-13-0) in F344/N Rats... 10.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr523.pdf

    ... NOS Historical Incidence: All Routes Benzophenone (feed) 8/50 0/50 0/50 8/50 ... All Routes Acrylonitrile (gavage) 2/50 Benzophenone (feed) 1/50 Bromodichloromethane ...

  49. TR-595: Sprague Dawley (Hsd:Sprague Dawley SD) Rats Exposed to... 5.6MB

    https://ntp.niehs.nih.gov/go/tr595

    ... perfluorooctanoic acid, dietary zinc, p-chloro- α,α,α-trifluorotoluene, dibutyl phthalate, 2-hydroxy-4-methoxy-benzophenone, and diethylhexyl phthalate (2 studies). ...

  50. Historical Controls: By Route and Vehicle for Mice; Studies started... 644KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_rte20071000_508.pdf

    ... Battelle Columbus Laboratory 058813804 09/14/99 730 50(1) 44(717) 46.0 Benzophenone ... Battelle Columbus Laboratory 058813804 09/13/99 729 50(5) 40(706) 46.2 Benzophenone ...

 
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