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National Institute of Environmental Health Sciences: Georgia... 154KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/georgia
Skip Navigation Georgia K. Roberts, Ph.D. National Institute of Environmental Health Sciences (NIEHS) Office of Program Operations Much of the work carried out by DTT is in support ...
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Application of Defined Approaches for Skin Sensitization to Agrochemic... 968KB
https://ntp.niehs.nih.gov/iccvam/meetings/11wc/posters/strickland-dass-wc11-poster.pdf
. The assessment of skin sensitization potential is included in international regulatory safety evaluations of pesticides. . Although several non-animal test methods based on key ...
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Highlights From 2020 OECD WNT Meeting (ICCVAM Public Forum 2020... 284KB
https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2020/ppt/15-oecd-hall-508.pdf
OECD TEST GUIDELINES PROGRAMME UPDATE ICCVAM Public Forum Webcast Thursday, 21 May 2020 Wanda Hall USG National Coordinator for the OECD TG Programme (hall.wanda@epa.gov) 2 No. ...
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Presentation: Developing AOPs from PPAR Activation Leading to... 738KB
https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/nepelska-508.pdf
www.jrc.ec.europa.eu Serving society Stimulating innovation Supporting legislation Peroxisome proliferator-activated receptors (PPARs) activation leading to reproductive toxicity ...
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ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf
... (1/1) POS (1/1) POS (1/1) Ethyl paraben 120-47-8 POS POS I (1) POS (1/1) POS (1/1) ... Class d Product Class e Ethyl paraben 120-47-8 POS POS 2.48 × 10 -5 Carboxylic Acid, ...
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Comment: Draft Report 05 Dated March 21, 2021; J.C. DiNardo;... 243KB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/publiccomm/dinardo_oxybenzone20210928_trprp_508.pdf
5 Dated March 21, 2021 NTP Developmental and Reproductive Toxicity Technical Report on the Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... phenolic Pharmaceutical Ethyl paraben 120-47-8 Paraben; Organic acid Pharmaceutical ... (Presumed Positive) Ethyl paraben e 120-47-8 0.0006 1/1 1 Binds weakly to ER Paraben; ...
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Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... by EPA and in vivo by OECD Ethyl paraben 120-47-8 Carboxylic Acid, Phenol Pharmaceutical, ... Veterinary Agent Ethyl paraben 120-47-8 166.2 Y n.d. 885 mg/L @ 25 °C - 2.47 $8 ...
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NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf
... Positive Positive Estrone 53-16-7 POS Positive Positive Positive Ethylparaben 120-47-8 POS Positive Positive Positive Fenarimol 60168-88-9 POS Negative NT NT Flutamide ...
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Protocol: Evidence Map of Inflammation-Based Atherosclerosis... 643KB
https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosis_supplementaljuly2023_508.pdf
EVIDENCE MAP OF INFLAMMATION-BASED ATHEROSCLEROSIS ASSOCIATED WITH ENVIRONMENTAL EXPOSURES July 2023 Integrative Health Assessments Branch Division Translational Toxicology ...
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TOX-21: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) 21.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox021.pdf
National Toxicology Program Toxicity Report Series Number 21 NTP Technical Report on Toxicity Studies of 2-Hydroxy-4-methoxybenzophenone (CAS Number: 131-57-7) Adminstered ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... > 99% Sigma Powder Ethyl paraben 120-47-8 Paraben; Organic acid Pharmaceutical ... - 1.79E-10 2.97E-02 62% Ethyl paraben 120-47-8 P + - - - Active Viable 1.26E-05 - ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... > 99% Sigma Powder Ethyl paraben 120-47-8 Paraben; Organic acid Pharmaceutical ... - 1.79E-10 2.97E-02 62% Ethyl paraben 120-47-8 P + - - - Active Viable 1.26E-05 - ...
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Draft TR-600: Di-n-butyl Phthalate (CASRN 84-74-2) Administered... 2.0MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr600_508.pdf
Di-n-butyl Phthalate (CASRN 84-74-2) 3 Administered in Feed to Sprague Dawley 4 (Hsd:Sprague Dawley ® SD ® ) Rats 5 and B6C3F1/N Mice 6 Technical Report 600 7 February 2021 8 ...
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TR-600: Di-n-butyl Phthalate Administered in Feed to Sprague... 3.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf
di-N-buTyl PhThalaTe (casRN 84-74-2) admiNisTeRed iN feed To sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs aNd b6c3f1/N mice NTP TR 600 NOVEMBER 2021 NTP Technical Report on ...
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Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds The Results of an Independent Peer Review Evaluation ...
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Draft DART-05: Modified One-Generation Study of 2-Hydroxy-4-methoxyben... 3.3MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/dart05_508.pdf
Hydroxy-4-methoxybenzophenone 4 (CASRN 131-57-7) Administered in Feed to 5 Sprague Dawley (Hsd:Sprague Dawley ® SD ® ) 6 Rats with Prenatal and Reproductive 7 Performance ...
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DART-05: Modified One-Generation Study of 2-Hydroxy-4-methoxybenzophen... 6.0MB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart05_508.pdf
hyDRoxy-4-meTho xybeNzoPheNoNe (caSRN 131-57-7) aDmiNiSTeReD iN feeD To SPRaGue Dawley (hSD:SPRaGue Dawley ® SD ® ) RaTS wiTh PReNaTal aND RePRoDucTive PeRfoRmaNce aSSeSSmeNTS iN ...
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ICCVAM Test Method Evaluation Report: In Vitro Test Methods for... 42.0MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/invitro-2010/tmer-vol1.pdf
ICCVAM Test Method Evaluation Report: Current Validation Status of In Vitro Test Methods Proposed for Identifying Eye Injury Hazard Potential of Chemicals and Products Interagency ...
