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Search suggestions for "120-80-9".

  1. CEBS Data Related to Catechol (120-80-9) https://cebs.niehs.nih.gov/cebs/test_article/120-80-9


72 results found for "120-80-9".

  1. RoC Background Document: Steroidal Estrogens; Dec. 13-14, 2000 1.7MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/se_no_appendices_508be.pdf

    ... species, with aromatic hydroxylation to catechol intermediates and glucuronidation, ... Sato and Aizu- Yokota (1996) tested several natural estrogens and their catechol ...

  2. TR-380: l-Epinephrine Hydrochloride (CASRN 55-31-2) in F344/N... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr380.pdf

    ... hydrochloride; methylaminoethanol catechol hydrochloride Trade Names for ... hydrochloride; methylaminoethanol catechol hydrochloride Trade Names for ...

  3. TR-289: Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1Mice... 16.4MB

    https://ntp.niehs.nih.gov/go/tr289

    ... 222 GENETIC TOXICOLOGY O F BENZENE. CATECHOL. AND HYDROQUINONE .....223 INDUCTION O F ... 224 MUTAGENICITY O F CATECHOL IN SALMONELLA ......

  4. TOX-70: p-tert-Butylcatechol (CASRN 98-29-3) 4.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox070.pdf

    ... isobutylene with catechol in the presence of ion exchange resins (Kirk-Othmer, 1980). ... Hirose et al. (1989) cited results of in vitro studies in which derivatives of catechol ...

  5. Abstract for TR-380 65KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr380

    ...dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride; methylaminoethanol catechol hydrochloride Report Date: March 1990 Full Report PDF Abstract l-Epinephrine,an ...

  6. RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf

    ... µg CIB (1991) Hoffmann and Hecht (1989) Catechol 58-290 µg 22.6-86.5 µg CIB (1991) ... Concentration range type Low High Units Catechol MS 148.00 362.00 µg/cig Catechol SS ...

  7. Stomach, Glandular Stomach, Epithelium - Hyperplasia - Nonneoplastic... 299KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Epithelium-Hyperplasia

    in the glandular stomach induced by oral administration of catechol to male F344 rats. ... Hirose M, Wada S, Yamaguchi S, Masuda A, Okazaki S, Ito N. 1992. Reversibility of catechol...

  8. Stomach, Glandular Stomach, Epithelium - Hyperplasia, Atypical... 291KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Epithelium-HyperplasiaAtypical

    in the glandular stomach induced by oral administration of catechol to male F344 rats. ... Hirose M, Wada S, Yamaguchi S, Masuda A, Okazaki S, Ito N. 1992. Reversibility of catechol...

  9. Stomach, Glandular Stomach, Epithelium - Hyperplasia, Atypical 292KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/hypat/glandular-stomach-hyperplasia-atypical-pdf_508.pdf

    ... in the glandular stomach induced by oral administration of catechol to male F344 rats. ... Okazaki S, Ito N. 1992. Reversibility of catechol-induced rat glandular stomach lesions. ...

  10. Stomach - Edema - Nonneoplastic Lesion Atlas 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Edema

    K, Lin C, Saito K, Kaneko H, Shirai T. 1999. Sequential morphological and biological changes in the glandular stomach induced by oral administration of catechol to male F344 rats. ...

  11. Stomach, Glandular Stomach - Edema 305KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/edema/glandular-stomach-edema_508.pdf

    K, Lin C, Saito K, Kaneko H, Shirai T. 1999. Sequential morphological and biological changes in the glandular stomach induced by oral administration of catechol to male F344 rats. ...

  12. Stomach, Glandular Stomach, Epithelium - Hyperplasia 893KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/epihyp/glandular-stomach-epithelium-hyperplasia-pdf_508.pdf

    ... in the glandular stomach induced by oral administration of catechol to male F344 rats. ... Okazaki S, Ito N. 1992. Reversibility of catechol-induced rat glandular stomach lesions. ...

  13. Stomach - Erosion - Nonneoplastic Lesion Atlas 291KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Erosion

    ... K, Lin C, Saito K, Kaneko H, Shirai T. 1999. Sequential morphological and biological changes in the glandular stomach induced by oral administration of catechol to male F344 rats. ...

  14. Stomach - Ulcer - Nonneoplastic Lesion Atlas 291KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Ulcer

    ... K, Lin C, Saito K, Kaneko H, Shirai T. 1999. Sequential morphological and biological changes in the glandular stomach induced by oral administration of catechol to male F344 rats. ...

  15. Stomach, Glandular Stomach - Erosion 324KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/erosion/glandular-stomach-erosion_508.pdf

    ... K, Lin C, Saito K, Kaneko H, Shirai T. 1999. Sequential morphological and biological changes in the glandular stomach induced by oral administration of catechol to male F344 rats. ...

  16. Stomach, Glandular Stomach - Ulcer 263KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/ulcer/glandular-stomach-ulcer_508.pdf

    ... K, Lin C, Saito K, Kaneko H, Shirai T. 1999. Sequential morphological and biological changes in the glandular stomach induced by oral administration of catechol to male F344 rats. ...

  17. TR-543: alpha-Methylstyrene (CASRN 98-83-9) in F344/N Rats and... 8.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr543.pdf

    ... stabilized with 4-tert-butyl catechol to inhibit oxidation and polymerization ... Concentrations of 4-tert-butyl catechol were well above the 8 ppm action criteria as a ...

  18. GMM-08: Genetically Modified Model Report on Benzene (Gavage... 1.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm08_508.pdf

    ... by the cytochrome enzymes to phenol, catechol, and hydroquinone, as well as enzyme ... Phenol is further metabolized (via CYP450) to hydroquinone and catechol. Hydroquinone and ...

  19. GMM-12: Genetically Modified Model Report on Phenolphthalein... 768KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm12_508.pdf

    ... A catechol metabolite of phenolphthalein, hydroxyphenolphthalein (PT-CAT), has been ... These authors hypothesize that PT-CAT inhibits the enzyme catechol-O-methyltransferase ...

  20. TR-403: Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1Mice... 15.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr403.pdf

    ... Although both p-tert-butyl catechol and p-methyl catechol promote the development of neoplasms of the forestomach and glandular stomach in MNNG- 13 Introduction treated rats, ...

  21. TR-495: Sodium Nitrite (CASRN 7632-00-0) IN F344/N Rats and B6C3F1Mice... 16.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr495.pdf

    ... (e.g., phenol, 3-methoxycatechol, catechol, vanillin, and butylated hydroxyanisole) ... when sodium nitrite was given with catechol or 3-methoxycatechol than when catechol ...

  22. RoC Profile: Estrogens, Steroidal; 15th RoC 2021 161KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/estrogenssteroidal.pdf

    ... estriol are metabolized via similar phase I pathways (aromatic hydroxylation to catechol intermediates) and phase II path- ways (glucuronidation, sulfonation, and O-methylation). ...

  23. TR-366: Hydroquinone (CASRN 123-31-9) in F344/N Rats and B6C3F1Mice... 14.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr366.pdf

    ... conver- sion of phenol to hydroquinone, catechol, and other hydroxylated benzenes. ... with evidence that hydroquinone and catechol (or metabolites of these compounds) are ...

  24. TR-574: Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1... 13.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr574_508.pdf

    ... > hydroquinone > catechol) and is one of only two polyphenols able to produce . ... after incubation with rat catechol- O-methyl transferase (COMT) (Masri et al., 1964). ...

  25. TR-548: Ethinyl Estradiol (CASRN 57-63-6) in Sprague-Dawley Rats... 6.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr548.pdf

    ... stress and direct DNA binding of catechol metabolites of estrogens has been ... been attributed to the low generation of catechol metabo- lites and oxidative stress ...

  26. TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf

    ... A number o f minor metabolites o f 5,5diphenylhydantoin have been identified. These include dihydrodiol (DHD), a catechol, m-HPPH, a methylated catechol, and diphenylhydantoin ...

  27. RoC Background Document: 2,3,7,8-Tetrachlorodibenzo-p-dioxin... 7.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrachl_tcdd_4apps_508.pdf

    ... of a production of genotoxic metabolites through redox cycling of catechol estrogens. ... P450 CYP1A2, which is hypothesized to metabolize estradiol to form catechol estrogens. ...

  28. Documents Provided to the NTP Board of Scientific Counselors... 55.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf

    ... genotypes [met/val or met/met]) in the catechol- O-methyltransferase (COMT) gene ... polymorphism in the COMT gene (i.e., catechol-O-methyltransferase), which results in ...

  29. TR-585: Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice... 3.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr585_508.pdf

    ... EGCG = epigallocatechin gallate; COMT = catechol-O-methyltransferase; SULT = ... Catechin polyphenols have been reported to inhibit catechol-O- methyltransferase in human ...

  30. TR-585: Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice... 3.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr585_508.pdf

    ... EGCG = epigallocatechin gallate; COMT = catechol-O-methyltransferase; SULT = ... Catechin polyphenols have been reported to inhibit catechol-O- methyltransferase in human ...

  31. RoC Background Document for Diazoaminobenzene; Nov. 22, 2002 1.3MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/daab_rg2_public_correct_no_app_508.pdf

    ... Phenol may be oxidized by cytochrome P-450 2E1 to hydroquinone or catechol. Catechol also may be formed by dehydrogenation of the 1,2-dihydrodiol intermediate. The 1,2-dihydrodiol ...

  32. TR-255: 1,2-Dichlorobenzene (o-Dichlorobenzene) (CASRN 95-50... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr255.pdf

    ... The presence of catechol and mercapturic acid metabolites suggests the possi- bility of an ... is not metabolized to catechols or mercapturic acid (Azouz et al., 1955) ...

  33. TOX-73: Diazoaminobenzene (CASRN 136-35-6) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox073.pdf

    ... sulfate Benzoquinone glucuronide Phenol glucuronide R Phenyl sulfate R Phenol M Catechol Catechol sulfate Catechol glucuronide Trihydroxy benzene Trihydroxy benzene glucuronide ...

  34. TR-562: Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats... 6.4MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr562.pdf

    ... a product of methylenedioxy ring opening and catechol formation, jatrorrhizine (methylation of the catechol), and 3,10-demethylpalmatine, a product of multiple pathways (Figure 2). ...

  35. TR-322: Phenylephrine Hydrochloride (CASRN 61-76-7) in F344/N... 10.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr322.pdf

    ... Although not a catechol, it exhibits phar- macologic actions resembling several endoge- nous catecholamines (Meyer and Fraunfelder, 1980). Phenylephrine is an a-receptor agonist ...

  36. TR-261: Chlorobenzene (CASRN 108-90-7) in F344/N Rats and B6C3F1Mice... 10.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr261.pdf

    ... ides, 27% ethereal sulfates, 20% mercapturic acids), catechols (27%), and phenols (3%). ... excreted in urine (e.g., phenols and catechols, glucuronide and sulfate conju- gates, ...

  37. TR-466: Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr466.pdf

    ... to form phenol, catechol, and benzo- quinones (hydroquinones) and excreted in the urine or exhaled (NTP, 1986). Alternatively, oxidation and ring opening of catechol give rise to ...

  38. NTP Working Group Report: Draft State of the Science Monograph... 20.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/wgrptbsc20230400.pdf

    ... polymorphisms in dopamine receptor D2 or catechol-O-methyltransferase (Cui et al. 2018; ... polymorphisms in dopamine receptor D2 or catechol-O-methyltransferase (Cui et al. 2018; ...

  39. NTP Board of Scientific Counselors Working Group Report on the... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/bsc_wg_report_final_version_bsc_approved051623_508.pdf

    ... polymorphisms in dopamine receptor D2 or catechol-O-methyltransferase (Cui et al. 2018; ... polymorphisms in dopamine receptor D2 or catechol-O-methyltransferase (Cui et al. 2018; ...

  40. NTP Working Group Report: Draft State of the Science Monograph... 9.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/meeting_materials/wgrptbsc20230400_interimver_508.pdf

    ... polymorphisms in dopamine receptor D2 or catechol-O-methyltransferase (Cui et al. 2018; ... polymorphisms in dopamine receptor D2 or catechol-O-methyltransferase (Cui et al. 2018; ...

  41. TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf

    ... the toxic agent in both species is the liver metabolite 1,Zdihydroxynaph- thalene, different metabolic routes are involved: phenol oxidase in rats and catechol oxidase in rabbits. ...

  42. TOX-9: Cresols (CASRNs 95-48-7, 108-39-4, 106-44-5) 6.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox009.pdf

    ... Biochemical and behavioral effects of some substi- tuted catechols. Arch. Int Pharmacodyn. ... V. (1970). Depigmentation from 4-tertiary butyl catechol - an experimental study. /. ...

  43. Public Comment: Ethylbenzene; Jack Snyder; RoC; Jan. 19, 2012 288KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2012/publiccomm/snyder20120228.pdf

    ... of one or more reactive metabolites (catechols, quinones), are postulated to play a key ... or as a result of the formation of one or more reactive metabolites (catechols, quinones). ...

  44. TR-500: Naphthalene (CASRN 91-20-3) in F344/N Rats (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr500.pdf

    ... in both species is the liver metabolite 1,2-dihydroxynaphthalene, phenol oxidase was the primary metabolic enzyme in rats and catechol oxidase was the primary enzyme in rabbits. ...

  45. TR-319: 1,4-Dichlorobenzene (CASRN 106-46-7) in F344/N Rats and... 17.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr319.pdf

    ... In contrast to other dichlorobenzenes, mercap- turic acids and catechols were not found as me- tabolites in the rabbit. Hawkins et al. (1980) compared tissue distri- bution and ...

  46. TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf

    ... release of newly synthesized catechol- amines into the synaptic cleft, and methylphenidate stimulating the release of stored o r granular poolsof catecholamines(Finn et al., 1990). ...

  47. TR-534: Divinylbenzene-HP (CASRN 1321-74-0) in F344/N Rats and... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr534.pdf

    ... Because the divinylbenzene monomer readily polymerizes to a brittle insoluble resin, it is heavily inhibited with tert- butyl catechol and diluted with ethylvinylbenzene to ...

  48. TR-491: Methyleugenol (CASRN 93-15-2) in F344/N Rats and B6C3F1Mice... 22.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr491.pdf

    ... The epoxides of allylbenzene are relatively stable. The conversion of safrole epoxide to catechol epoxide demonstrated that the cleavage of the methylenedioxy group may occur with ...

  49. TR-569: Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine... 7.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr569_508.pdf

    ... of the tertiary butyl moiety; a catechol, designated M3, that results from ... M1, that results from methylation of the catechol metabolite; and two diastereomers, ...

  50. TR-446: 1-Trans-Delta9-Tetrahydrocannabinol (CASRN 1972-08-3... 16.4MB

    https://ntp.niehs.nih.gov/go/tr446

    ... the change in brain 5-hydro~- tryptamine levels (Watanabe et al., 1984) and suggested that the effectis mediated by catechol- amines (Yagiela et al., 1974; Singh and Das, 1976). ...

 
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