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TR-240: Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1Mice... 6.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr240.pdf
BIOASSAY OF PROPYL GALLATE (CAS NO. 121-79-9) IN F344 RATS AND B6C3F1 MICE (FEED ... CARCINOGENESIS BIOASSAY OF PROPYL GALLATE (CAS NO. 121-79-9) IN F344/N RATS A N D B6C3F1 ...
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Propyl gallate: Target Organs and Levels of Evidence for TR-240 57KB
https://ntp.niehs.nih.gov/data/tr/200s/tr240levels
(CASRN 121-79-9) in F344/N Rats and B6C3F1 Mice (Feed Study) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Propyl gallate 121-79-9 12/16/...
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Abstract for TR-240 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr240
Carcinogenesis Bioassay of Propyl Gallate in F344/N Rats and B6C3F1 Mice (Feed Study) CASRN: 121-79-9 Chemical Formula: C10H12O5 Molecular Weight: 212.20 Synonyms/Common Names: ...
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TR-585: Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice... 3.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr585_508.pdf
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TR-585: Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice... 3.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr585_508.pdf
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Abstract for TR-585 80KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr585
5abs Abstract for TR-585 Toxicology Studies of Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Green Tea Extract in Wistar Han ...
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Peer Review Report of the EpiSensA Skin Sensitization Assay ... 1.5MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-reinke-poster.pdf
Peer Review Report of the EpiSensA Skin Sensitization Assay E.N. Reinke 1 , E. Corsini 2 , A. Ono 3 , T. Fukuyama 4 , T. Ashikaga 5 , G.F. Gerberick 6 1 Inotiv, RTP, NC; 2 ...
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PowerPoint Presentation 925KB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/knudsenposter.pdf
U.S. Environmental Protection Agency Office of Research and Development EPA www.epa.gov EVALUATION OF 1066 TOXCAST CHEMICALS IN A HUMAN STEM CELL ASSAY FOR DEVELOPMENTAL TOXICITY ...
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Adverse Outcome Pathways: From Research to Regulation 76KB
https://ntp.niehs.nih.gov/whatwestudy/niceatm/3rs-meetings/past-meetings/aop-wksp-2014
Adverse Outcome Pathways: From Research to Regulation September 3-5, 2014 William H. Natcher Conference Center National Institutes of Health Bethesda, Maryland, USA Videocasts of ...
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ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf
... ester; Propyl 3,4,5- trihydroxybenzoate 121-79-9 212.20 NA High Solid Carboxylic acids ... et al. 2008 + ICCVAM 1999 Propyl gallate 121-79-9 2.5 4.95 + + - - - + + + + + + + + + + ...
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Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf
... 50-21-5 N N/A NC NC NC 4-Nitrobenzyl bromide 100-11-8 N N/A 1A 1 1A Propyl gallate 121-79-9 Y N/A 1A 1 1A Resorcinol 108-46-3 N N/A 1B NC 1B Salicylic acid 69-72-7 N N/A 1B NC ...
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Reproducing the ITS-2 Model Using R 472KB
https://ntp.niehs.nih.gov/iccvam/methods/immunotox/its-os/its2_r_version-508.pdf
... 0.906084 0.062214 0.002272 0.029430 121-79-9 0.000443 0.000907 0.776881 0.221769 ... 0.906084 0.062214 0.002272 0.029430 121-79-9 0.000443 0.000907 0.776881 0.221769 ...
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All Past Events 1004KB
https://ntp.niehs.nih.gov/events/past
https://ntp.niehs.nih.gov/go/meeting All Past Events The sidebars on this page are hidden to provide an optimal data view. may prevent you from viewing the data in an optimal ...
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Presentation: The Murine Local Lymph Node Assay: DA 1010KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf
Murine Local Lymph Node Assay: Daicel Chemical Industries, Ltd., Based on ATP Content (LLNA: DA) ICCVAM Workshop Series on Best Practices for Regulatory Safety Testing: Assessing ...
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RR-06: Baseline Characteristics of Diversity Outbred (J:DO) Mice... 672KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr06_508.pdf
BaseliNe chaRacTeRisTics of DiveRsiTy ouTBReD (J:Do) Mice RelevaNT To Toxicology sTuDies NTP RR 6 JUNE 2018 NTP Research Report on Baseline Characteristics of Diversity Outbred ...
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Validation of the Electrophilic Allergen Screening Assay (EASA... 1.3MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-gordon-poster.pdf
Validation of the Electrophilic Allergen Screening Assay (EASA) to Detect Substances that Impact the Initial Key Event in the Adverse Outcome Pathway for Skin Sensitization J. ...
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Minutes: TR Panel; May 22, 2014 273KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2014/may/minutes20140522_508.pdf
National Toxicology Program Technical Reports Peer Review Panel Meeting May 22, 2014 National Institute of Environmental Health Sciences Research Triangle Park, NC Summary Minutes ...
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TR-150: Butylated Hydroxytoluene (BHT) (CASRN 128-37-0) 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr150.pdf
National Cancer Institute CARCINOGENESIS Technical Report Series No. 150 1979 BIOASSAY OF BUTYLATED HYDROXYTOLUENE (BHT) FOR POSSIBLE CARCINOGENICITY CAS No. 128-37-0 ...
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TR-238: Ziram (CASRN 137-30-4) in F344/N Rats and B6C3F1Mice... 11.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr238.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 238 CARClNOG EN ESI S BIOASSAY OF ZIRAM (CAS NO. 137-30-4) IN F344/N RATS AND B6C3F1 MICE (FEED STUDY) U.S. DEPARTMENT OF ...
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TR-459: t-Butylhydroquinone (CASRN 1948-33-0) in F344 Rats and... 25.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr459.pdf
NATIIONAL T O X I I C O L O G ~ PII~OGII~L~]~'iI T e c ~ e ~ ~ o ~ ~erb~ , Ne. 459 ~ST-~VICI~$04 " T © X J I C © L © G Y ANII> CAXCIIN©GENIZSff$ $ T ~ f f E 5 ©~ ...
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CERHR Monograph: Hydroxyurea 3.6MB
https://ntp.niehs.nih.gov/ntp/ohat/hydroxyurea/humonograph20090401.pdf
National Toxicology Program U.S. Department of Health and Human Services Center for The Evaluation of Risks To Human Reproduction NTP-CERHR MoNogRaPH oN THE PoTENTial HuMaN ...
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TR-235: Zearalenone (CASRN 17924-92-4) in F344/N Rats and B6C3F1Mice... 6.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr235.pdf
5 CARClNOGENESlS BIOASSAY OF ZEARALENONE (CAS NO. 17924-92-4) IN F344/N RATS A N D B6C3F1 MICE (FEED STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...
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Submission of the CertiChem Cell Proliferation Test Method for... 3.1MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/submdoc.pdf
TEST METHOD NOMINATION: MCF-7 CELL PROLIFERATION ASSAY OF ESTROGENIC ACTIVITY This nomination application includes no confidential information. TABLE OF CONTENTS Page # I ...
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Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
... Propyl gallate// Tenox PG// 3,4,5-Trihydroxybenzoic acid propyl ester 121-79-9 benzoate ... β-Propiolactone 57-57-8 + Propylgallate 121-79-9 + + 1-Propyl-3-nitro-1-nitrosoguanidine ...
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Public Comment: 2-Butoxyethanol (Attachment); Seth Barna; RoC... 758KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/barna_attachmentacc_508be.pdf
Attachment 2 Page 1 of 56 Kimberly Bateman 10/1/2013 Search Descriptions for Searches Related to the Registration of Butoxyethanol CAS# 111-76-2 Searches Conducted Sept. 27 th and ...
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TR-341: Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr341.pdf
1 (""l '<J TOXICOLOGY AND CARCINOGENESIS STUDIES OF NITROFURANTOIN (CAS NO. 67-20-9) IN F344/N RATS AND B6C3FI MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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TR-345: Roxarsone (CASRN 121-19-7) in F344/N Rats and B6C3F1... 25.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr345.pdf
5 (/~ <~>~~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF ROXARSONE (CAS NO. 121-19-7) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...
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NICEATM Pre-screen Evaluation: MCF-7 Cell Proliferation Assay... 258KB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/cciprescreeneval.pdf
NICEATM Pre-Screen Evaluation of the In Vitro Endocrine Disruptor Assay (Robotic MCF-7 Cell Proliferation Assay of Estrogenic Activity) EVALUATION NICEATM 16 October 2006 NICEATM ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Species/Sex E Equivocal Evidence E Equivocal Evidence TR-240 12/16/81 Propyl gallate 121-79-9 E Equivocal Evidence N No Evidence E Equivocal Evidence N No Evidence TR-239 12/16/81 ...
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Minutes: BSC TRRS; June 16, 1982 632KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1982/june/82june16trrsmin_508.pdf
Board o f S c i e n t i f i c Counselors N a t i o n a l Toxicology Program Summary M i nu t e s from Peer Reviews o f D r a f t Technical Reports o f Long-Term Carcinogenesis ...
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TR-271: HC Blue No. 1 (CASRN 2784-94-3) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/go/tr271
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 271 b?l =wc,> TOXICOLOGY AND CARCINOGENESIS STUDIES OF MC BLUE NO. 1 (CAS NO.2784-94-3) IN F344/N RATS AND B6C3F1 MICE (FEED ...
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TR-299: C.I. Disperse Blue 1 (A commercial dye containing approximatel... 15.0MB
https://ntp.niehs.nih.gov/go/tr299
299 +LIMAN 5 4 3 ' . J TOXICOLOGY AND CARCINOGENESIS STUDIES OF C.I. DISPERSE BLUE 1 (A commercial dye containing approximately 50% 1,4,5,8-tetraaminoanthraquinone, 30% other ...
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TR-557: beta-Myrcene (CASRN 123-35-3) in F344/N Rats and B6C3F1... 16.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr557.pdf
$-MYRCENE (CAS NO. 123-35-3) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 December 2010 NTP TR 557 ...
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TR-234: Allyl Isothiocyanate (CASRN 57-06-7) in F344/N Rats and... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr234.pdf
4 CARCINOGENESIS BIOASSAY OF ALLYL ISOTHIOCYANATE (CAS NO. 57-06-7) IN F344/N RATS AND 86C3Fl MICE (GAVAGE STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...
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TR-236: D-Mannitol (CASRN 69-65-8) in F344/N Rats and B6C3F1Mice... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr236.pdf
6 CARCINOGENESIS BIOASSAY OF D-MAN NITOL (CAS NO. 69-65-8) IN F344/N RATS AND B6C3F1 MICE (FEED STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National ...
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TR-293: HC Blue No. 2 [2,2'-((4-((2-Hydroxyethyl)amino)-3-nitrophenyl... 8.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr293.pdf
3 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HC BLUE NO.2 2,2'.((4-((2-HYDROXYETHYL)AMIN0)-3-NITROPHENYL)IMINO)BIS(ETHANOL) (CAS NO. 33229-34-4) IN F344/N RATS AND B6C3Ft MICE (FEED ...
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TR-364: Rhodamine 6G (C.I. Basic Red 1) (CASRN 989-38-8) in F344... 11.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr364.pdf
NO. 364 TOXICOLOGY AND CARCINOGENESIS STUDIES OF RHODAMINE 6G (C.I. BASIC RED 1) (CAS NO. 989-38-8) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... N/A Technical Report TR-240 PDF (6.89 MB) Carcinogenesis Bioassay of Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1 Mice (Feed Study) 1982 Technical Report TR-239 PDF ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... N/A Long-Term Carcinogenicity TR-240 PDF (6.89 MB) Carcinogenesis Bioassay of Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1 Mice (Feed Study) 1982 Long-Term ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... N/A Technical Report TR-240 PDF (6.89 MB) Carcinogenesis Bioassay of Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1 Mice (Feed Study) 1982 Technical Report TR-239 PDF ...
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RR-16: Scoping Review of Paraquat Dichloride Exposure and Parkinson... 2.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr16_508.pdf
PaRaquaT DichloRiDe exPosuRe aND PaRkiNsoN's Disease NTP RR 16 SEPTEMBER 2020 NTP Research Report on the Scoping Review of Paraquat Dichloride Exposure and Parkinson's Disease ...
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Literature Search Results: Systematic Review of Fluoride Exposure... 768KB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf
LITERATURE SEARCH RESULTS FOR THE SYSTEMATIC REVIEW OF FLUORIDE EXPOSURE AND NEURODEVELOPMENTAL AND COGNITIVE HEALTH EFFECTS September 16, 2020 Office of Health Assessment and ...
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Validation, Qualification, and Regulatory Acceptance of New Approach... 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/VWG_Report_27Feb2024_FD_508.pdf
Advancing Alternatives to Animal Testing U N I T E D S T A T E S Validation, Qualification, and Regulatory Acceptance of New Approach Methodologies March 2024 doi:10.22427/...
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Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... Trihydroxybenzoic acid, propyl ester; Benzoic acid, 3,4,5- trihydroxy-, propyl ester 121-79-9 212.20 1.80 Solid High Carboxylic acids Food additive C-299 'l < q~ I 0 0 ~o~ 0 O Q I ...
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Documents Provided to the NTP Board of Scientific Counselors... 55.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf
DRAFT NTP Monograph on the State of the Science Concerning Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Systematic Review NTP Monograph 08 September ...
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TR-223 Carcinogenesis Studies of Eugenol (CASRN 97-53-0) in F344... 6.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr223.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 223 CARCINOGENESIS STUDIES OF EUGENOL (CAS NO. 97-53-0) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF ...
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TR-540: Methylene Blue Trihydrate (CASRN 7220-79-3) in F344/N... 10.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr540.pdf
... National Toxicology Program (NTP) (1982). Carcinogenesis Bioassay of Propyl Gallate (CAS No. 121-79-9) in F344 Rats and B6C3F 1 Mice (Feed Study). Technical Report Series No. 240. ...
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TR-574: Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1... 13.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr574_508.pdf
PYROGALLOL (CAS NO. 87-66-1) IN F344/N RATS AND B6C3F1/N MICE (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 February 2013 NTP TR 574 ...
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TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf
6 TOXICOLOGY AND CARCINOGENESIS STUDIES O F ETHYLENE OXIDE (CAS NO. 75-21-8) IN B6C3F1 MIiCE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...
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ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
ICCVAM Test Method Evaluation Report The Reduced Murine Local Lymph Node Assay: An Alternative Test Method Using Fewer Animals to Assess the Allergic Contact Dermatitis Potential ...