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Abstract for TR-394 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr394
CASRN: 103-90-2 Chemical Formula: C8H9NO2 Molecular Weight: 151.16 Synonyms/Common Names: 4-Hydroxyacetanilide; N-acetyl-p-aminophenol; paracetamol Report Date: January 1993 Full ...
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RoC Background Document for Nitrobenzene; Sept. 19, 2002 1.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/nbpub_no_appendices_508.pdf
... Figure 1-2. Structures of p-nitrophenol (4-nitrophenol) and p-aminophenol ... of nitrobenzene are p-nitrophenol (4-nitrophenol) and p-aminophenol (4-aminophenol). ...
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TR-394: Acetaminophen (CASRN 103-90-2) in F344 Rats and B6C3F1Mice... 14.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr394.pdf
... 4-Hydroxyacetanilide, N-Acetyl-p-aminophenol, Paracetamol Acetaminophen is a widely ... 4-Hydroxyacetanilide, N-Acetyl-p-aminophenol, Paracetamol activity in 1893 by von ...
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TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf
... manufacture of parathion insecticides to acetaminophen (M-acetyl-p-
aminophenol or AF'AP). ... amounts, to p-aminophenol by nitro- reduction or to p-nitrocatechol by hydroxylation. ...
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TR-211 Carcinogenesis Studies of C.I. Acid Orange 10 (CASRN 1936... 7.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr211.pdf
... the dose was excreted in the urine as p-
aminophenol and 6% was excreted in urine and 22% ... in urine as p-aminophenol, 3% as o-aminophenol, and 0.6% as aniline (Daniel, 1962). ...
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TR-351: para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in... 12.2MB
https://ntp.niehs.nih.gov/go/tr351
... information is available on p-
aminophenol, one of the purported metabolites of p-chloroaniline (Ichikawa et al., 1969). Al- though p-aminophenol is not generally observed to be ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... also part of the RC (acetonitrile, p-aminophenol, caffeine, coumarin, ... of + log 5, and for two chemicals (p-aminophenol and caffeine), the predicted LD50 ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... sulfate 0.06 2.6 1086.8 42 p-Aminophenol 0.062 15.2 1658.9 187 ... 97 Phenacetin 1.27 9.21 1650.8 42 p-Aminophenol 0.062 15.2 1658.9 248 m-Aminophenol ...
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Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
... Piperidene solvent 110-89-4 Mercuric chloride metal salt 7487-94-7 4-Aminophenol solvent 123-30-8 4.0 Reference Data Used for Performance Assessment In LD50 studies using OECD TG ...
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TR-403: Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1Mice... 15.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr403.pdf
... Biometrics 33, 386-389. Spengler, J., Osterburg, I., and Korte, R. (1986). Teratogenic evaluation of p-toluenediamine sulfate resorcinol and p-aminophenol in rats and rabbits. ...
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ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... evaluation of N-acetyl-p-aminophenol, salicylamide, and acetylsalicylic acid. ... evaluation of N-acetyl-p-aminophenol, salicylamide, and acetylsalicylic acid. ...
