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TR-431: Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1Mice... 15.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr431.pdf
1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZYL ACETATE (CAS NO. 140-11-4) IN F344/N RATS AND B6C3F, MICE (FEED STUDIES) U.S.DEPARTMENT OF HEALTHANDHUMANSERVICES ...
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TR-250: Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1Mice... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr250.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 250 +~~,.,. su"'"t.r (~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZYL ACETATE (CAS N 0 . 140-11 -4) IN F344/N RATS AND ...
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TOX-48: Allyl Acetate (CASRN 591-87-7), Allyl Alcohol (CASRN... 18.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox048.pdf
National Toxicology Program Toxicity Report Series Number 48 NTP Technical Report on the Comparative Toxicity Studies of Allyl Acetate, Allyl Alcohol, and Acrolein (CAS Nos. ...
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TR-252: Food Grade Geranyl Acetate (71 Geranyl Acetate, 29Citronellyl... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr252.pdf
N A T I O N A L T O X I C O L O G Y P R O G R A M Technical Report Series No. 252 CARCl NOG EN ESlS STU DIES OF FOOD GRADE GERANYL ACETATE (71% GERANYL ACETATE, 29% CITRONELLYL ...
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Nomination Background: Isoamyl acetate (CASRN: 123-92-2) 205KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/isoamylacetate_508.pdf
SUMMARY OF DATA FOR CHEMICAL SELECTION Isoamyl Acetate CAS No. 123-92-2 Prepared for NTP by Technical Resources International, Inc Prepared on 11/94 Under NCI Contract No. ...
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Abstract for TR-431 70KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr431
1abs Abstract for TR-431 Toxicology and Carcinogenesis Studies of Benzyl Acetate in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 140-11-4 Chemical Formula: C9H10O2 Molecular ...
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Abstract for TOX-48 71KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox048
8abs Abstract for TOX-48 Comparative Toxicity Studies of Allyl Acetate, Allyl Alcohol and Acrolein Administered by Gavage to F344/N Rats and B6C3F1 Mice Substances: Allyl acetate ...
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Abstract for TR-250 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr250
0abs Abstract for TR-250 Toxicology and Carcinogenesis Studies of Benzyl Acetate in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 140-11-4 Chemical Formula: C9H10O2 Molecular ...
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Abstract for TR-252 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr252
2abs Abstract for TR-252 Carcinogenesis Studies of Food Grade Geranyl Acetate (71% Geranyl Acetate, 29% Citronellyl Acetate) in F344/N Rats and B6C3F1 Mice (Gavage Study) CASRN: ...
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Abstract for RACB82102 61KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb82102
2abs Abstract for RACB82102 Lead Acetate Trihydrate: Reproduction and Fertility Assessment in CD-1 Mice When Administered in the Drinking Water CASRN: 301-04-2 Chemical Formula: ...
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Abstract for RACB84059 61KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84059
9abs Abstract for RACB84059 Lead Acetate Trihydrate: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Drinking Water CASRN: 301-04-2 Chemical Formula: ...
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Abstract for RACB94009 65KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb94009
9abs Abstract for RACB94009 Reproductive Toxicity of in Lead Acetate Trihydrate in Sprague-Dawley Rats CASRN: 6080-56-4 Chemical Formula: C4H6O4Pb3H2O Molecular Weight: 379.33 ...
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Abstract for RACB85054 62KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb85054
4abs Abstract for RACB85054 Ethylene Glycol Monoethyl Ether Acetate: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Drinking Water CASRN: 111-15-9 Chemical ...
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Target Organs and Levels of Evidence for TR-252 57KB
https://ntp.niehs.nih.gov/data/tr/200s/tr252levels
88 Target Organs and Levels of Evidence for TR-252 Carcinogenesis Studies of Food Grade Geranyl Acetate (71% Geranyl Acetate, 29% Citronellyl Acetate) (CASRN 105-87-3) in F344/N ...
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RoC Profile: Lead and Lead Compounds; 15th RoC 2021 190KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/lead.pdf
Lead and Lead Compounds CAS No. 7439-92-1 (Lead) No separate CAS No. assigned for lead compounds as a class Reasonably anticipated to be human carcinogens First listed in the ...
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Target Organs and Levels of Evidence for TR-250 58KB
https://ntp.niehs.nih.gov/data/tr/200s/tr250levels
4 Target Organs and Levels of Evidence for TR-250 Toxicology and Carcinogenesis Studies of Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical ...
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Target Organs and Levels of Evidence for TR-431 57KB
https://ntp.niehs.nih.gov/data/tr/400s/tr431levels
2 Target Organs and Levels of Evidence for TR-431 Toxicology and Carcinogenesis Studies of Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1 Mice Feed Studies) Chemical ...
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Abstract for TER20001 63KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter20001
1abs Abstract for TER20001 Developmental Toxicity Evaluation for Silver Acetate Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6-19 CASRN: 563-63-3 ...
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Abstract for RACB83098 67KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb83098
8abs Abstract for RACB83098 Ethylene Glycol Monomethyl Ether: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Drinking Water CASRN: 109-86-4 Chemical ...
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RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf
FINAL Report on Carcinogens Background Document for Lead and Lead Compounds May 8, 2003 Prepared for the: U.S. Department of Health and Human Services Public Health Service ...
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Abstract for TR-80 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr080
0abs Abstract for TR-80 Bioassay of 1,4-Dioxane for Possible Carcinogenicity CASRN: 123-91-1 Chemical Formula: C4H8O2 Molecular Weight: 88.1052 Report Date: 1978 Full Report PDF ...
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RoC Background Document: Nickel Compounds; Dec. 2-3, 1998 6.7MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/nickelcompds1_oneapp_508.pdf
NICKEL COMPOUNDS FINAL MARCH 1999 Prepared for the December 2-3, 1998, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by ...
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RoC Profile: Norethisterone; 15th RoC 2021 125KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/norethisterone.pdf
Norethisterone CAS No. 68-22-4 Reasonably anticipated to be a human carcinogen First listed in the Fourth Annual Report on Carcinogens (1985) Also known as norethindrone O CH 3 OH ...
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TR-354: Dimethoxane (CASRN 828-00-2) (Commercial Grade) in F344... 11.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr354.pdf
4 TOXICOLOGY AND CARCINOGENESIS STUDIES OF DIMETHOXANE (CAS NO. 828-00-2) (COMMERCIAL GRADE) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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Minutes: BSC TRRS; Dec. 1, 1992 1003KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1992/dec/trrs1dec1992mins_508.pdf
and Short-Term Toxicity Studies by the Technical Reports Review Subcommittee December 1-2, 1992 Research Triangle Park, North Carolina The review meeting began a t 9:00 a.m. on ...
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Minutes: BSC TRRS; Nov. 2, 1984 839KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1984/nov/84nov2trrsmins_508.pdf
of S c i e n t i f i c Counselors National Toxicology Program Summary Minutes from Peer Reviews o f Draft Technical Reports o f Long-Term Toxicology and Carcinogenesis Studies by ...
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RR-17: Scoping Review of Prenatal Exposure to Progestogens and... 960KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr17_508.pdf
PReNaTal exPosuRe To PRogesTogeNs aNd adveRse healTh ouTcomes NTP RR 17 SEPTEMBER 2020 NTP Research Report on the Scoping Review of Prenatal Exposure to Progestogens and Adverse ...
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Japanese Minimum Requirements for Biological Products 2.0MB
https://ntp.niehs.nih.gov/iccvam/methods/biologics/vaccine/japan-minreqs.pdf
MINIMUM REQUIREMENTS FOR BIOLOGICAL PRODUCTS National Institute of Infectious Diseases Japan, 2006 - 1 - MINIMUM REQUIREMENTS FOR BIOLOGICAL PRODUCTS Notice: This English version ...
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RoC Background Document: Cadmium; Oct. 30-31, 1997 13.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cadmium_508.pdf
CADMIUM FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by Integrated ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 444 ONE-YEAR INITIATION/PROMOTION STUDY OF O-BENZYL-p-CHLOROPHENOL (CAS NO. 120-32-1) IN SWISS (CD-l@) MICE (MOUSE SKIN ...
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Abstract for TR-354 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr354
4abs Abstract for TR-354 Toxicology and Carcinogenesis Studies of Dimethoxane (Commercial Grade) in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 828-00-2 Chemical Formula: ...
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TR-441 Comparative Initiation/Promotion Skin Paint Studies of... 11.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr441.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 441 COMPARATIVE INITIATION/PROMOTION SKIN PAINT STUDIES OF B6C3Fl MICE, SWISS (CD-l@) MICE, AND SENCAR MICE U.S. DEPARTMENT ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
NIH Publication No: 03-4503 ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential Endocrine Disruptors: Estrogen Receptor and Androgen Receptor Binding and ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
71.1.1711999472.152.1804289383% X-Anytotx-Content-Type: application/pdf X-Anytotx-Identified-By: command-line Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: ...
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RoC Profile: Nickel Compounds and Metallic Nickel; 15th RoC 2021 170KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nickel.pdf
Nickel Compounds and Metallic Nickel Introduction Nickel compounds and metallic nickel have many industrial and com- mercial applications, including use in stainless steel and ...
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Abstract for TR-441 71KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr441
1abs Abstract for TR-441 Comparative Initiation/Promotion Skin Paint Studies of B6C3F1 Mice, Swiss (CD-1) Mice, and SENCAR Mice Substances: Benzoyl peroxide (CASRN 94-36-0) 7,12- ...
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RoC Profile: Nitroarenes (Selected); 15th RoC 2021 233KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitroarenes.pdf
Nitroarenes (Selected) Introduction The nitroarenes are a large class of structurally related chemicals nor- mally found in particulate emissions from many combustion sources, most ...
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TR-429: Diethylphthalate (CASRN 84-66-2) in F344/N Rats and B6C3F1Mice... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr429.pdf
N.A'll'mt:JlNAJL 'll'Ofil(()OllLOGY JPIROGAAM 'll'iecJlrumn(!!Eil IR~JJMDll"ll: §~lr'Ji~§ N®. 412~ T((J) :A\Il C(Q) ILCQ)(Q.1{ Af\TJD) CAIPlCITN (Q)G IE NIE§ JI§ §T1UJD) ...
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Abstract for TR-458 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr458
8abs Abstract for TR-458 Toxicology and Carcinogenesis Studies of Butyl Benzyl Phthalate in F344/N Rats (Feed Studies) CASRN: 85-68-7 Chemical Formula: C19H20O4 Molecular Weight: ...
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GMM-03: Genetically Modified Model Report on Trimethylolpropane... 7.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm03_508.pdf
The ToxicoloGy STudieS of TRiMeThylolPRoPaNe TRiacRylaTe (TechNical GRade) (caSRN 15625-89-5) iN f344/N RaTS, B6c3f1 Mice, aNd GeNeTically Modified (fVB TG.ac heMizyGouS) Mice ...
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GMM-04: Genetically Modified Model Report on Pentaerythritol... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm04_508.pdf
PeNTaeRyThRiTol TRiacRylaTe (TechNical GRade) (caSRN 3524-68-3) iN f344/N RaTS, B6c3f1 Mice, aNd GeNeTically Modified (fVB TG.ac heMizyGouS) Mice (deRMal STudieS) NTP GMM 04 ...
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TR-301: ORTHO-Phenylphenol (CASRN 90-43-7) Alone and with 7,12... 15.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr301.pdf
1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF ORTHO-PHENYLPHENOL (CAS NO. 90-43-7) ALONE AND WITH 7,12-DIMETHYLBENZ(a)ANTHRACENE (CAS NO. 57-97-6) IN SWISS CD-1 MICE (DERMAL STUDIES) ...
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Vagina - Angiectasis - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/vagina/Angiectasis
Dilated vessels in the rat vagina are rarely observed. When present as angiectasis, they are usually a collection of prominent dilated blood vessels lined by a single layer of ...
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Abstract for TR-430 75KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr430
0abs Abstract for TR-430 Toxicology and Carcinogenesis Studies of C.I. Direct Blue 218 in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 28407-37-6 Chemical Formula: ...
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TR-456: 1,2-Dihydro-2,2,4-Trimethylquinoline (CASRN 147-47-7... 17.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr456.pdf
FOREWORD The National Toxicology Program (NTP) is made up of four charter agencies of the U.S. Department of Health a:nd Human Services (DHHS): the National Cancer Institute (NCI), ...
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Vagina - Angiectasis 273KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/vagina/angiect/vagina-angiectasis-pdf-508.pdf
Angiectasis Figure Legend: Figure 1 Vagina - Angiectasis in a female F344/N rat from a chronic study. Dilated blood vessels are present in the wall of the vagina. Figure 2 Vagina - ...
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Nomination Background: 1,3-Dichloro-2-propanol (CASRN: 96-23... 1.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dichloropropanol_508.pdf
1,3-Dichloro-2-propanol [CAS No. 96-23-1] Review of Toxicological Literature January 2005 1,3-Dichloro-2-propanol [CAS No. 96-23-1] Review of Toxicological Literature Prepared for ...
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Butyl benzyl phthalate: Target Organs and Levels of Evidence... 59KB
https://ntp.niehs.nih.gov/data/tr/400s/tr458levels
4 Butyl benzyl phthalate: Target Organs and Levels of Evidence for TR-458 Toxicology and Carcinogenesis Studies of Butyl Benzyl Phthalate (CASRN 85-68-7) in F344 Rats (Feed ...
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Vagina - Hypertrophy, Stromal - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/vagina/HypertrophyStromal
Stromal hypertrophy of the vagina is characterized by thickening of the fibromuscular stroma of the vaginal wall due to an increase in the size of cells, not the number of cells ...
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TR-183: Dibutyltin Diacetate (CASRN 1067-33-0) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr183.pdf
P8 2 9 ! 5 6 7 O National Cancer Institute 55 c CARCINOGENESIS Technical Report Series No. 183 1979 o m m BIOASSAY OF DIBUTYLTIN DIACETATE FOR POSSIBLE CARCINOGENICITY Z CAS No. ...