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104 results found for "132-22-9".

  1. TR-317: Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats... 10.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr317.pdf

    AND CARCINOGENESIS STUDIES OF CHLORPHENIRAMINE MALEATE (CAS NO. 113-92-8) IN F344/N ... NCI, was transferred to the NIEHS. Chlorpheniramine Maleate, NTP TR 317 NTP TECHNICAL ...

  2. Abstract for TR-317 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr317

    Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate in F344/N Rats and ... Toxicology and carcinogenesis studies of chlorpheniramine maleate (99% pure), a widely ...

  3. Target Organs and Levels of Evidence for TR-317 57KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr317levels

    Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate (CASRN 113-92-8) in .../Exposure Levels Study Laboratory Chlorpheniramine maleate 113-92-8 12/09/1985 Gavage ...

  4. Modernizing Drug Discovery Using (ICCVAM Communities of Practice... 6.0MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2023/20230130-iccvam-cop-ewart-508.pdf

    ... Benoxaprofen Metabolism leading to toxic intermediate No Yes Beta-Estradiol Inhibition of transporter No Yes Chlorpheniramine Reactive Oxygen Species production No Yes Labetalol ...

  5. Minutes: BSC TRRS; Dec. 9, 1985 520KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1985/dec/85dec9trrsmins_508.pdf

    ... Crowley , Jones, Purchase, and Turnbull). Chlorpheniramine Maleate. Dr. R. Melnick, NTP Chemical Manager, introduced the toxicoloav and carcinoaenesis studies of chlorpheniramine ...

  6. TR-374: Glycidol (CASRN 556-52-5) In F344/N Rats and B6C3F1Mice... 11.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr374.pdf

    ... (b) Malonaldehyde, sodium salt (c) Chlorpheniramine maleate ( c ) Tetrakis(hydroxymethy1... Malonaldehyde, sodium salt (d) 0150 Chlorpheniramine maleate (d) 0150 Tetrakid ...

  7. TR-355: Diphenhydramine Hydrochloride (CASRN 147-24-0) in F344... 10.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr355.pdf

    ... Administration of 2,000 ppm diphenhydramine hydrochloride or 1,000 ppm chlorpheniramine ... Thus, in vivo nitrosation of diphenhydramine or chlorpheniramine may produce carcinogenic ...

  8. TR-352: N-Methylolacrylamide (CASRN 924-42-5) in F344/N Rats... 27.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr352.pdf

    ... (b) Malonaldehyde, sodium salt (c) Chlorpheniramine maleate (c) Tetrakis(hydroxymethyl)p... (b) Malonaldehyde, sodium salt (c) Chlorpheniramine maleate (c) Tetrakis(hydroxymethyl)p...

  9. TR-328: Methyl Carbamate (CASRN 598-55-0) in F344/N Rats and... 10.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr328.pdf

    ... in All Water Gavage Controls (b) Chlorpheniramine maleate Tetrakis(hydroxymethy1)phosp... in All Water Gavage Controls (b) Chlorpheniramine maleate 12/50 0150 12/50 ...

  10. TR-331: Malonaldehyde, Sodium Salt (3-Hydroxy-2-propenal, Sodium... 7.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr331.pdf

    ... Battelle Columbus Laboratories (b) Chlorpheniramine maleate 21/49 Tetrakis(hydroxymethyl... Battelle Columbus Laboratories (b) Chlorpheniramine maleate 3/50 Tetrakis(hydroxymethyl)...

  11. TR-340: Iodinated Glycerol (Organidin) (CASRN 5634-39-9) in F344... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr340.pdf

    ... (b) Malonaldehyde, sodium salt (c) Chlorpheniramine maleate (c) Tetrakis(hydroxymethy1)p... sodium salt (c) 3/50 1150 4/50 Chlorpheniramine maleate (c) 0150 1/50 1150 ...

  12. TR-366: Hydroquinone (CASRN 123-31-9) in F344/N Rats and B6C3F1Mice... 14.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr366.pdf

    ... Malonaldehyde, sodium salt (c) 0150 Chlorpheniramine maleate (c) 0150 ... (b) Malonaldehyde, sodium salt (c) Chlorpheniramine maleate (c) Tetrakis(hydroxyrnethy1)...

  13. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Equivocal Evidence NE No Evidence NE No Evidence NE No Evidence TR-317 12/09/85 Chlorpheniramine Maleate 113-92-8 NE No Evidence NE No Evidence NE No Evidence NE No Evidence ...

  14. TR-351: para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in... 12.2MB

    https://ntp.niehs.nih.gov/go/tr351

    ... sodium salt 5/50 0/50 5/50 Chlorpheniramine maleate 21149 0/49 21149 ... glycerol Malonaldehyde, sodium salt Chlorpheniramine maleate Tetrakis(hydroxymethyl)phosp...

  15. TR-296: Tetrakis(hydroxymethyl)phosphonium sulfate (THPS) (CASRN... 16.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr296.pdf

    ... Chlorpheniramine maleate (b) TOTAL SD Overall Historical Incidence in Untreated Controls ... Vehicle Controls THPS (b) THPC (b) Chlorpheniramine maleate (b) TOTAL SD (c) 21/50 17/50 ...

  16. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Technical Report TR-317 PDF (10.58 MB) Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1986 ...

  17. TR-495: Sodium Nitrite (CASRN 7632-00-0) IN F344/N Rats and B6C3F1Mice... 16.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr495.pdf

    ... and Denlinger, 1975 F344 rats Diphenhydramine Liver Lijinsky, 1984a (males) and chlorpheniramine Allantoin Forestomach Lijinsky, 1984a Sprague-Dawley rats Heptamethyleneimine ...

  18. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Carcinogenicity TR-317 PDF (10.58 MB) Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1986 ...

  19. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Technical Report TR-317 PDF (10.58 MB) Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1986 ...

  20. TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 321 ...

  21. TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 ...

  22. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    ... Mirex 314 Methyl Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 ...

  23. TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf

    ... Mirex Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane ...

  24. TR-266: Monuron (CASRN 150-68-5) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr266.pdf

    ...(2-chloro-1-methylethyl)ether 316 1-Chloro-2-methylpropene 240 Propyl Gallate 317 Chlorpheniramine Maleate 242 Diallyl Phthalate (Mice) 318 Ampicillin Trihydrate 244 Polybrominated ...

  25. TR-335: C.I. Acid Orange 3 (CASRN 6373-74-6) in F344/N Rats and... 12.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr335.pdf

    ... 240 Propyl Gallate 316 1-Chloro-2-methylpropene 242 Diallyl Phthalate (Mice) 317 Chlorpheniramine Maleate 244 Polybrominated Biphenyl Mixture 318 Ampicillin Trihydrate 245 ...

  26. TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf

    ... Methacry late 315 Oxytetracycline Hydrochloride 316 l-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 ...

  27. TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 l-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 ...

  28. TR-409: Quercetin (CASRN 117-39-5) in F344 Rats (Feed Studies... 9.6MB

    https://ntp.niehs.nih.gov/go/tr409

    ... Mirex Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane ...

  29. TR-278: 2,6-Xylidine (2,6-Dimethylaniline) (CASRN 87-62-7) in... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr278.pdf

    ... Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-DichIorobenzene Rotenone Bromodichloromethane ...

  30. TR-320: Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1Mice... 11.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr320.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 321 ...

  31. TR-330: 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr330.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 l,4-Dichlorobenzene 320 Rotenone 321 ...

  32. TR-333: N-Phenyl-2-naphthylamine (CASRN 135-88-6) in F344/N Rats... 9.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr333.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 321 ...

  33. TR-336: Penicillin VK (CASRN 132-98-9) in F344/N Rats and B6C3F1Mice... 9.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr336.pdf

    ... 238 Ziram 316 1-Chloro-2-methylpropene 239 Bis(2-chloro-1methylethyl)ether 317 Chlorpheniramine Maleate 240 Propyl Gallate 318 Ampicillin Trihydrate 242 Diallyl Phthalate (Mice) ...

  34. TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf

    ... (Mice) Propyl Gallate Bis(2chloro-1-methylethy1)ether 317 316 315 314 313 312 Chlorpheniramine Maleate 1-Chloro-2-methylpropene Oxytetracycline Hydrochloride Methyl ...

  35. TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate ,I ~- k 319 1,4-Dichlorobenzene .< 320 Rotenone ...

  36. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... Chlorpheniramine Maleate 317 C.I. Acid Orange 3 335 C.I. Acid Orange 10 211 C.I. Acid Red 14 220 C.I. Acid Red 114 405 C.I. Basic Red 9 Monohydrochloride 285 C.I. Direct Blue 15 ...

  37. TR-323: Dimethyl Methylphosphonate (CASRN 756-79-6) in F344/N... 9.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr323.pdf

    ... Methacry late 315 Oxytetracycline Hydrochloride 316 l-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 321 ...

  38. TR-329: 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1Mice... 10.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr329.pdf

    ... Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Bromodichloromethane ...

  39. TR-332: 2-Mercaptobenzothiazole (CASRN 149-30-4) in F344/N Rats... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr332.pdf

    ... 238 Ziram 316 1-Chloro-2-methylpropene 239 Bis(2-chloro-1methy1ethyl)ether 317 Chlorpheniramine Maleate 240 Propyl Gallate 318 Ampicillin Trihydrate 242 Diallyl Phthalate (Mice) ...

  40. TR-338: Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats... 10.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr338.pdf

    ... 240 Propyl Gallate 316 1-Chloro-2-methylpropene 242 Diallyl Phthalate (Mice) 317 Chlorpheniramine Maleate 244 Polybrominated Biphenyl Mixture 318 Ampicillin Trihydrate 245 ...

  41. TR-339: 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr339.pdf

    ... 238 Ziram 316 1-Chloro-2-methylpropene 239 Bis(2-chloro-1-methylethy!)ether 317 Chlorpheniramine Maleate 240 Propyl Gallate 318 Ampicillin Trihydrate 242 Diallyl Phthalate <Mice) ...

  42. TR-373: Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr373.pdf

    ... Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane ...

  43. TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf

    ... Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylpropene 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 ...

  44. TR-321: Bromodichloromethane (CASRN 75-27-4) in F344/N Rats and... 10.6MB

    https://ntp.niehs.nih.gov/go/tr321

    ... Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Phenylephrine Hydrochloride ...

  45. TR-337: Nitrofurazone (CASRN 59-87-0) in F344/N Rats and B6C3F1Mice... 10.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr337.pdf

    ... 238 Ziram 316 1-Chloro-2-methylpropene 239 Bis(2-chloro-1-methylethyl)ether 317 Chlorpheniramine Maleate 240 Propyl Gallate 318 Ampicillin Trihydrate 242 Diallyl Phthalate (Mice) ...

  46. TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf

    ... Melamine 317 Chlorpheniramine Maleate 246 ChrysotileAsbestos (Hamsters) 247 L - F b i c Acid 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 248 4,4 Methylenedianiline ...

  47. TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr391.pdf

    ... Mirex Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane ...

  48. TR-401: 2,4-Diaminophenol Dihydrochloride (CASRN 137-09-7) in... 12.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr401.pdf

    ... Mirex Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane ...

  49. TR-406: g-Butyrolactone (CASRN 96-48-0) in F344/N Rats and B6C3F1Mice... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr406.pdf

    ... Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane Phenylephrine Hydrochloride Dimethyl Methylphosphonate Boric Acid ...

  50. TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr412.pdf

    ... Mirex Methyl Methacrylate Oxytetracycline Hydrochloride 1-Chloro-2-methylpropene Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane ...

 
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