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RoC Background Document: 2,3,7,8-Tetrachlorodibenzo-p-dioxin... 7.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrachl_tcdd_4apps_508.pdf
... Dibenzofurans), 2,3,7,8-TCDD, pp. 3-343, 525-630, 1997 ...... A-1 APPENDIX ... of action ofTCDD and other chlorinated dibenzodioxins, dibenzofurans, and planar PCBs. ...
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RoC Profile: 2,3,7,8-Tetrachlorodibenzo-p-dioxin; 15th RoC 2021 154KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/tetrachlorodibenzodioxin.pdf
chlorinated dibenzodioxins, dibenzofurans, and planar polychlorinated biphenyls (PCBs). ... the specific CDD and polychlori- nated dibenzofuran (CDF) congeners relative to that of ...
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Abstract for TR-525 75KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr525
Weight: 340.4 Synonyms/Common Names: Dibenzofuran, 2,3,4,7,8-pentachloro-; ... polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...
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TR-525: 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CASRN 57117... 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr525.pdf
... 5 O Molecular Weight: 340.4 Synonyms: Dibenzofuran, 2,3,4,7,8-pentachloro-; ... polychlorinated dibenzodioxins (PCDDs), polychlori- nated dibenzofurans (PCDFs), and PCBs. ...
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TR-526: a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD... 9.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr526.pdf
... 5 O Molecular Weight: 340.42 Synonyms: Dibenzofuran, 2,3,4,7,8-pentachloro-; ... polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...
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Presentation: Adverse Outcome Pathway (AOP) for Sustained Aryl... 822KB
https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/simon-508.pdf
chemicals ¤ Dioxins, PCBs, Dibenzofurans ¤ Other planar polyaromatic hydrocarbons ¤ Natural phytochemicals, flavinoids and indoles ¤ Multiple endogenous ligands proposed, e.g. ...
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TR-521: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) (CASRN 1746... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr521.pdf
... polychlorinated dibenzodioxins (PCDDs), polychlori- nated dibenzofurans (PCDFs), and PCBs. ... (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls ...
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TR-520: 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465... 16.2MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr520.pdf
... polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ... (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls ...
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TR-529: 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065... 7.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr529.pdf
... (PCDDs), polychlori- nated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). ... (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls ...
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RoC Concept: Pentachlorophenol 299KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/concepts/pcp_concdocroc8-30-12_508.pdf
... chlorinated congeners of dibenzo-p- dioxins, and dibenzofurans) formed during production. ... dibenzo-p-dioxins including 2,3,7,8-TCDD, and polychlorinated dibenzofurans. ...
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Abstract for TR-521 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr521
... a part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...
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Abstract for TR-520 76KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr520
... a part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...
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Abstract for TR-529 71KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr529
... to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). ...
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Abstract for TR-526 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr526
... as part of the dioxin TEF evaluation to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and PCBs. ...
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Abstract for TR-530 82KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr530
... to assess the cancer risk posed by complex mixtures of polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). ...
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RoC Monograph: Pentachlorophenol and By-products of Its Synthesis... 2.9MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/pentachlorophenol_508.pdf
... molecules, particularly chlorinated dibenzo-p- dioxins and dibenzofurans (see below). ... DD = dibenzo-p-dioxins; DF = dibenzofurans; NS = not specified. a Goldstein et al. (1977), ...
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15th RoC: Acronyms 58KB
https://ntp.niehs.nih.gov/ntp/roc/content/acronyms_508.pdf
... aromatic hydrocarbon PCDD polychlorinated dibenzodioxin PCDF polychlorinated dibenzofuran PCP pentachlorophenol PCR polymerase chain reaction PEL permissible exposure limit ...
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TR-483: Pentachlorophenol (CASRN 87-86-5) in F344/N Rats (Feed... 7.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr483.pdf
... NTP TR 483 of polychlorinated dibenzo-p-dioxins and poly- chlorinated dibenzofurans. ... dibenzo-p-dioxins and chlorinated dibenzofurans, may affect the rate of ...
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TR-559: 2,3',4,4',5-Pentachlorobiphenyl (PCB 118)(CASRN 31508... 6.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr559.pdf
... (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls ... Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and ...
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TR-530: a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl ... 13.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr530.pdf
... (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls ... One impurity was not identified, but was determined not to be a dioxin, dibenzofuran, or ...
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TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB
https://ntp.niehs.nih.gov/go/tr349
... dibenzodioxins and dibenzofurans, in the carcino- genic effects observed in mice. ... For assessment of the hepatic effects of any di- benzodioxin or dibenzofuran content of ...
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Acronyms & Abbreviations 80KB
https://ntp.niehs.nih.gov/support/acronyms
... diphenyl ethers PCDD Polychlorinated dibenzodioxin PCDF Polychlorinated dibenzofuran PCP Pentachlorophenol PCR Polymerase chain reaction PEL Permissible exposure limit ...
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RoC Profile: Pentachlorophenol and By-products of Its Synthesis... 220KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/pentachlorophenol.pdf
... of chlorinated dibenzo-p-dioxins and dibenzofurans among former Michigan trichlorophenol ... 2008. Chlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyl profiles of workers with ...
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TOX-105: Usnea Lichens Containing (+/-)-Usnic Acid (CASRN 125... 4.2MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox105_508.pdf
... and include depsidones, depsides, dibenzofuranes, depsones, quinones, pulvinic acid ... diphenyl ether derivatives, and dibenzofurans. 16 The dibezofurane, (+/-)-usnic acid ...
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Minutes: BSC TRRS; Feb. 17, 2004 661KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2004/feb/trrs17feb2004mins_508.pdf
... and carcinogenesis studies of 2,3,4,7,8- pentachlorodibenzofuran (PeCDF), by noting it is the most potent polychlorinated dibenzofuran in the Toxic Equivalency Factor scheme. ...
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Draft RoC Monograph for Pentachlorophenol: Literature Search... 2.0MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/pcpliteraturesearch20130815_508.pdf
... of chlorinated dibenzo-p-dioxins and dibenzofurans among former Michigan trichlorophenol ... 2008. Chlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyl profiles of workers with ...
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RoC Profile: Polybrominated Biphenyls; 15th RoC 2021 140KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/polybrominatedbiphenyls.pdf
... 2006. Occurrence of polybrominated biphenyls, polybrominated dibenzo-p-dioxins, and polybrominated dibenzofurans as impurities in commercial polybrominated diphenyl ether mixtures. ...
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RoC Profile: Polychlorinated Biphenyls; 15th RoC 2021 176KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/polychlorinatedbiphenyls.pdf
... dibenzo- dioxins, and polychlorinated dibenzofurans (Beyer and Biziuk 2009). ... trends, and comparison with dioxins, dibenzofurans, and polychlorinated biphenyls. ...
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TOX-104: (+)-Usnic Acid (CASRN 7562-61-0) Administered in Feed... 4.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox104_508.pdf
... CASRN 7562-61-0, is a bright-yellow dibenzofuran compound, which occurs naturally as a ... of (-)-pseudoplacodiolic acid, a new dibenzofuran, from the lichen Rhizoplaca chrysoleuca. ...
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Protocol: Systematic Review of Inflammation-based Atherosclerosis... 1001KB
https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosisjuly2023_508.pdf
... OR 120-12-7:rn OR 129-00-0:rn OR 132-
64-9:rn OR 132-65-0:rn OR 191-24-2:rn OR ... OR 120-12-7[rn] OR 129-00-0[rn] OR 132-64-9[rn] OR 132-65-0[rn] OR 191-24-2[rn] OR ...
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RoC Background Document: Furan; Nov. 18-19, 1996 3.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/furan1_508.pdf
... Generally, the "furans" meant by these regulations are polychlorinated dibenzofurans ... by 110-00-9 and/or furan by name are really on polychlorinated dibenzofurans (PCDFs). ...
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TR-589: Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade... 7.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr589_508.pdf
... To assess the relative potencies of polybrominated dibenzo-p-dioxins/dibenzofurans, female ... Exposure to the three dibenzofurans resulted in a reduction in the antibody response ...
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TR-558: 3,3',4,4'-Tetrachloroazobenzene (TCAB) (CASRN 14047-09... 22.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr558.pdf
... dibenzo-p-dioxins and dibenzofurans together (NTP, 1998a; Van Birgelen et al., 1999a). ... in the envi- ronment than polychlorinated dibenzo-p-dioxins and dibenzofurans together. ...
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TR-201: Carcinogenesis 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr201.pdf
... Conference on Chlorinated Dibenzodioxins and Dibenzofurans held in April 1973. Environ. ... hazards of polychlorinated dibenzodioxins and polychlorinated dibenzofurans. Environ. ...
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TOX-65: 3,3',4,4'-Tetrachloroazobenzene 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox065.pdf
... as polychlorinated dibenzo-p-dioxins, dibenzofurans, biphenyls, and naphthalenes, involves ... polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs and PCDFs) in the rat. Arch. ...
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TOX-66: 3,3',4,4'-Tetrachloroazoxybenzene 3.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox066.pdf
... as polychlorinated dibenzo-p-dioxins, dibenzofurans, biphenyls, and naphthalenes, involves ... polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs and PCDFs) in the rat. Arch. ...
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Minutes: BSC TRRS; June 23, 1992 1.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1992/june/trrs23june1992mins_508.pdf
... brominated dibenzofurans, compounds for which there had been recent toxicity studies reported. Dr. T. Goehl, NIEHS, said a mass spectral analysis had been done for dibenzofurans. ...
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TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf
... biphenyls, dibenzodioxins and dibenzofurans which are known o r suspected toxins, ... N o chlorinated di- benzodioxins, dibenzofurans, o r diphenyl ethers were detected in lots ...
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Protocol: Evaluation of Human Cancer Studies on Exposure to Pentachlor... 363KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/pcphumanstudies20130815_508.pdf
... Chlorinated dibenzo-p-dioxins, dibenzofurans and biphenyl profiles of workers with ... Serum concentrations of chlorinated dibenzo-p-dioxins and dibenzofurans among former ...
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TOX-28: Tetrachlorophthalic Anhydride (CASRN 117-08-8) 1.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox028.pdf
... bulk chemical was also analyzed by high-resolution gas chromatography/mass spectroscopy/selected ion monitoring for the presence of 16 chlorinated dibenzodioxins and dibenzofurans. ...
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TR-209: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN 1746-01-6... 8.5MB
https://ntp.niehs.nih.gov/go/tr209
... Conference on Chlorinated Dibenzodioxins and Dibenzofurans held in April 1973. Environ. ... hazards of polychlorinated dibenzodioxins and polychlorinated dibenzofurans. Environ. ...
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Response Peer Review Report: RoC Peer Review; Dec. 12-13, 2013 238KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2013/december/responsepeerrevrep20131212_508.pdf
... LL, Budinsky RA, Martin GD, Carson ML. 2008. Chlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyl profiles of workers with trichlorophenol and pentachlorophenol exposures. ...
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TOX-6: Pentachlorobenzene (CASRN 608-93-5) 3.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox006.pdf
... dibenzodioxins or dibenzofurans were detected in the study material (detection limits ranged from 100 to 1,000 ppb for the in- dividual dibenzodioxins and dibenzofurans). ...
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RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
... Crumb Rubber B-5 Name CASRN Molecular Wt Dibenz(a,h)anthracene 53-70-3 278.35 Dibenzofuran 132-64-9 168.19 2-Dibenzofuranamine 3693-22-9 183.21 3-Dibenzofuranamine 4106-66-5 183.21 ...
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Minutes: BSC TRRS; April 18, 1988 4.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf
... studies did not support an important role for the impurities of pentachlorophenol, chlorinated dibenzodioxins and dibenzofurans, in the carcinogenic effects observed in mice. Dr. ...
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TR-398: Polybrominated Biphenyls (CASRN 67774-32-7)(Firemaster... 14.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr398.pdf
... Dr. T.J. Goehl, NIEHS, said a mass spectral analysis had been done for dibenzofurans. The fragmentation patterns would indicate the number of bromines but not their position on the ...
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TR-531: a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl ... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr531.pdf
... Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and ... Teratogenic effects of polychlo- rinated dibenzofurans in combination in C57BL/6N mice. ...
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TOX-7: 1,2,4,5-Tetrachlorobenzene (CASRN 95-94-3) 4.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox007.pdf
... dibenzodioxins or dibenzofurans were detected in the study mate- rial (detection limits ranged from 200 to 3,000 ppb for the individual dibenzodioxins and di- benzofurans). ...
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Minutes: BSC; June 29, 2004 883KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2004/june/20040629_508.pdf
... biphenyls (PCBs), which are dioxin-like compounds, and polychlorinated dibenzofurans (PeCDFs). The validity of the use of TEFs for cancer risk assessment is uncertain. ...
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TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox077_508.pdf
... polychlorinated dibenzodioxins, dibenzofurans and related compounds in human environments. ... of chlorinated dibenzo-p-dioxins and dibenzofurans to hexachlorobenzene-induced toxicity, ...