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Abstract for TR-168 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr168
Abstract N-(1-Naphthyl)ethylenediamine dihydrochloride, a diagnostic reagent derived from 1-naphthylamine, was selected for bioassay by the National Cancer Institute because of the ...
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Abstract for TR-64 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr064
Full Report PDF Abstract 1-Nitronaphthalene is used as an intermediate for the preparation of 1-naphthylamine, which is used in the manufacture of numerous dyes and intermediates, ...
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RoC Background Document for Naphthalene; Sept. 19, 2002 4.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/naphthalenepub_508.pdf
... It formerly was used as an intermediate in 1-naphthylamine synthesis. Crystalline ... et al. 1997, Grosovsky et al. 1999). 1-Naphthylamine and 2-naphthylamine induced ...
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RoC Profile: 2-Naphthylamine; 15th RoC 2021 130KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/naphthylamine.pdf
... of 67 ng per cigarette was reported (Patrianakos and Hoffmann 1979). 2-Naph- thylamine also occurs as an impurity (0.5% or less) in commercially produced 1-naphthylamine. ...
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TR-333: N-Phenyl-2-naphthylamine (CASRN 135-88-6) in F344/N Rats... 9.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr333.pdf
... naphthylamine, mutagenicity data are available on only one, N-phenyl-1-naphthylamine. ... However, exposure to N - phenyl-1-naphthylamine did induce a slight, re- producible ...
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TR-168: N-(1-Naphthyl)ethylenediamine Dihydrochloride (CASRN... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr168.pdf
... dihydrochloride (Figure 1) (NCI No, CO3281), a diagnostic reagent derived from 1-naphthylamine, was selected for bioassay by the National Cancer Institute because of the ...
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Minutes: BSC; March 27, 1984 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf
... 2-naphthylamine (2-NA) and 2-aminofluorene, which are N-oxidized in rat and human liver, as contrasted with the non- carcinogen, 1-naphthylamine, which is not N-oxidized . ...
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Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf
... that rats dosed with aniline, 1-naphthylamine, or 2-NA excrete in the urine a very ... nitroso and N-hydroxy metabolites of 1-naphthylamine and 2-NA. 426 In rats treated with ...
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RoC Monograph: ortho-Toluidine; July 2014 2.4MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/otoluidine_508.pdf
... bicyclic and polycyclic aromatic amines (4-aminobiphenyl, 2-acetylaminofluorene, 1-naphthylamine, 2-naphthylamine, 4- nitrobiphenyl, benzidine, and N-acetylbenzidine) correlated ...
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TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf
... Genetics, 112 (1971), 289-294. 26. Mayer, V.W. "Induction of Mitotic Crossing Over in Saccharomyces cerevisiae by Breakdown Products of Dimethylnitrosamine 1-naphthylamine and ...
