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TR-330: 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr330.pdf
PROGRAM Technical Report Series No. 330 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 4-HEXYLRESORCINOL (CAS NO. 136-77-6) IN F344/N RATS AND B6C3Fi MICE (GAVAGE STUDIES) U.S. ...
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Abstract for TR-330 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr330
Abstract for TR-330 Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 136-77-6 Chemical Formula: C12H18O2 Molecular ...
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Target Organs and Levels of Evidence for TR-330 57KB
https://ntp.niehs.nih.gov/data/tr/300s/tr330levels
Target Organs and Levels of Evidence for TR-330 Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical ...
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Minutes: BSC TRRS; March 4, 1987 864KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1987/mar/87mar04trrsmins_508.pdf
-88-0 Gavage 1 Hexyl r e s o r c i no1 136-77-6 Gavage 3 Ma1 onal dehyde Gavage 5 Sodium ... o f carcinogenic a c t i v i t y of 4-hexylresorcinol f o r male% female k344/N r a t s ...
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Ovary - Necrosis - Nonneoplastic Lesion Atlas 288KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/Necrosis
National Toxicology Program. 1988. NTP TR-330. Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CAS No. 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies). NTP, ...
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Ovary - Necrosis 350KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/ovary/necrosis/ovary-necrosis-pdf-508.pdf
Elsevier, Amsterdam, 667-724. National Toxicology Program. 1988. NTP TR-330. Toxicology and Carcinogenesis Studies of 4-
Hexylresorcinol (CAS No. 136-77-6) in F344/N Rats and ...
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Bone - Increased Bone - Nonneoplastic Lesion Atlas 292KB
https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/bone/IncreasedBone
Chhabra RS, Huff JE, Haseman J, Hall A, Baskin G, Cowan M. 1988. Inhibition of some spontaneous tumors by 4-hexylresorcinol in F344/N rats and B6C3F1 mice. Fundam Appl Toxicol ...
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Bone - Increased Bone 474KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/musculoskeletal/bone/incbone/bone-increased-bone-pdf_508.pdf
... Bone References: Chhabra RS, Huff JE, Haseman J, Hall A, Baskin G, Cowan M. 1988. Inhibition of some spontaneous tumors by 4-hexylresorcinol in F344/N rats and B6C3F1 mice. ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Evidence P Clear Evidence NE No Evidence NE No Evidence TR-330 03/04/87 4-Hexylresorcinol 136-77-6 NE No Evidence NE No Evidence EE Equivocal Evidence NE No Evidence TR-329 08/...
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TR-339: 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr339.pdf
... were: 2-amino-5-nitrophenol--6/50; 4-hexylresorcinol--10/50; 2-mercaptobenzothia- ... Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol in F344/N Rats and B6C3Fl Mice. ...
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TR-442: p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr442.pdf
... the aminehitro substitution [e.g., 4-hexylresorcinol (NTP, 1988a) and p-Nitrobenzoic ... Rosenthal and Bauer, 1941) and 4-hexylresorcinol (NTP, 1988a; Burnens and Vurma-Pupp, ...
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TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf
... in male mice (NTP, 1987a), 4-hexylresorcinol in male mice (NTP, 1988b), 4,4' ... For 4-hexylresorcinol, the response in mice was judged equivocal. Six compounds containing ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... Studies of 4-Hexylresorcinol in F344/N Rats and B6C3F1 Mice (Gavage Studies). ... Type: Proposed Rule May 01, 2015 80 FR 25166 121-54-0 51-79-6 64-17-5 136-77-6 2015 OEHHA ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Report TR-330 PDF (9.39 MB) Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1988 Technical Report ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-330 PDF (9.39 MB) Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1988 Long-Term ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Report TR-330 PDF (9.39 MB) Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1988 Technical Report ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... p-Aminophenol 0.062 15.2 1658.9 187 4-Hexylresorcinol 0.064 2.83 549.9 43 Aldrin 0.067 ... Tributylamine 15.4 2.91 539.5 187 4-Hexylresorcinol 0.064 2.83 549.9 193 5-Azacytidine ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... 42 p- Aminophenol 23-30-8 6.77 0.062 1658.9 15.2 NA NA 109.14 15.2 187 4-
Hexylresorcinol 136-77-6 12.44 0.064 549.9 2.83 NA NA 194.3 2.83 43 Aldrin 309-00-2 24.45 0.067 40.1 ...
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TR-334: 2-Amino-5-Nitrophenol (CASRN 121-88-0) in F344/N Rats... 9.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr334.pdf
... 2-amino-4-nitrophenol (NTP,1988a), 4-hexylresorcinol (NTP, 1988b), and ... Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol in F344/N Rats and B6C3F1 Mice. ...
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TR-370: Benzofuran (CASRN 271-89-6) in F344/N Rats and B6C3F1Mice... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr370.pdf
... (a) 2,4-Dichlorophenol(D 4-Hexylresorcinol (c) n-Butyl chloride (g) ... (a) 2,4-Dichlorophenol (D 4-Hexylresorcinol (c) n-Butyl chloride (g) ...
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TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf
... Ethylene Oxide 327 Xylenes (Mixed) 328 Methyl Carbamate 329 1,2-Epoxybutane 330 4-Hexylresorcinol 331Malonaldehyde, Sodium Salt 332 2-Mercaptobenzothiazole 333 ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
... Pentachloronitrobenzene 326 Ethylene Oxide 327 Xylenes (Mixed) 328 Methyl Carbamate 329 1,ZEpoxybutane 330 4-Hexylresorcinol 331Malonaldehyde,SodiumSalt 332 2-Mercaptobenzothiazole ...
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TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf
... Ethylene Oxide 327 Xylenes (Mixed) 328 Methyl Carbamate 329 1,2-Epoxybutane 330 4-Hexylresorcinol 331 Malonaldehyde, Sodium Salt 332 2-Mercaptobenzothiazole 333 ...
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TR-409: Quercetin (CASRN 117-39-5) in F344 Rats (Feed Studies... 9.6MB
https://ntp.niehs.nih.gov/go/tr409
... Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epaxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiale N-Phenyl-2-naphthylamine ...
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TR-278: 2,6-Xylidine (2,6-Dimethylaniline) (CASRN 87-62-7) in... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr278.pdf
... Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt Mercaptobenzothiazole N-Phenyl-2-naphthylamine ...
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TR-335: C.I. Acid Orange 3 (CASRN 6373-74-6) in F344/N Rats and... 12.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr335.pdf
... Methyl Carbamate 259 Ethyl Acrylate 329 1,2-Epoxybutane 261 Chlorobenzene 330 4-Hexylresorcinol 263 1,2-Dichloropropane 331 Malonaldehyde, Sodium Salt 266 Monuron 332 ...
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TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf
... N-Phenyl-2-naphthylamine 2-Mercaptobenzothiamle Malonaldehyde, Sodium Salt 4-Hexylresorcinol 1,2-Epoybutane Methyl Carbamate Xylenes(Mixed) Ethylene Oxide ...
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TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf
... Ethylene Oxide 327 Xylenes (Mixed) 328 Methyl Carbamate 329 1,2-Epoxybutane 330 4-Hexylresorcinol 331 Malonaldehyde, Sodium Salt 332 2-Mercaptobenzothiazole 333 ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
... 2 HC Red 3 HC Yellow 4 Hexachlorocyclopentadiene Hexachloroethane 2,4-Hexadienal 4-Hexylresorcinol Hydrochlorothiazide Hydroquinone 8-Hydroxyquinoline Indium Phosphide Iodinated ...
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TR-338: Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr338.pdf
... Methyl Carbamate 259 Ethyl Acrylate 329 1,2-Epoxybutane 261 Chlorobenzene 330 4-Hexylresorcinol 263 1,L-Dichloropropane 331 Malonaldehyde, Sodium Salt 266 Monuron 332 ...
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TR-373: Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and... 21.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr373.pdf
... Ethylene Oxide Xylenes CMixed> Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt Mercaptobenzothiazole N-Phenyl-2-naphthylamine ...
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TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf
... Ethylene Oxide 327 Xylenes (Mixed) 328 Methyl Carbamate 329 1,2-Epoxybutane 330 4-Hexylresorcinol 331 Malonaldehyde, Sodium Salt 332 2-Mercaptobenzothiazole 333 ...
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TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf
... Ethyl Acrylate 329 1,2-Epoxybutane 261 Chlorobenzene 263 1,2-Dichloropropane 330 4-Hexylresorcinol 331Malonaldehyde,SodiumSalt 266 Monuron 267 1,2-Propylene Oxide 332 ...
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TR-368: Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1Mice... 13.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr368.pdf
... Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt Mercaptobenzothiazole N-Phenyl-2-naphthylamine ...
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TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr412.pdf
... Ethylene Oxide Xylenes (Mimed) Methyl Carbamate 12-Epaxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothimle N-Phenyl-2-naphthylamine ...
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TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr415.pdf
... Pentachloronittobenzene Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobemthiazole N-Phenyl-2-naphthylamine ...
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TR-419: HC Yellow 4 (CASRN 59820-43-8) in F344 Rats and B6C3F1Mice... 10.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr419.pdf
... Pentachloronitrobenne Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,ZEpoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiazole N-Phenyl-2-naphthylamine ...
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TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB
https://ntp.niehs.nih.gov/go/tr385
... Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiazole N-Phenyl-2-naphthylamine ...
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TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf
... Pentachloronitrobenzene Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzot hiazole N-Phenyl-2-naphthylami...
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TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr391.pdf
... Ethylene Oxide Xylenes (Mied) Methyl Carbamate 1,2-Epo~cybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiazole N-Phenyl-2-naphthylamine ...
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TR-395: Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1Mice... 16.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr395.pdf
... Pentachioronitrobenzene Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Maionaldehyde, Sodium Salt 2-Mercaptobenzothiazole N-Phenyl-2-naphthylamin...
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TR-396: Monochloroacetic Acid (CASRN 79-11-8) in F344/N Rats... 14.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr396.pdf
... Ethylene Oxide Xylenes (Mied) Methyl Carbamate 1,2-Epaxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothi~le N-Phenyl-2-naphthylamine ...
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TR-401: 2,4-Diaminophenol Dihydrochloride (CASRN 137-09-7) in... 12.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr401.pdf
... Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiamle N-Phenyl-2-naphthylamine ...
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TR-406: g-Butyrolactone (CASRN 96-48-0) in F344/N Rats and B6C3F1Mice... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr406.pdf
... Pentachloronitrobenne Ethylene Oxide Xylenes (Mied) MethylCarbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiale N-Phenyl-2-naphthylamine ...
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TR-408: Mercuric Chloride (CASRN 7487-94-7) in F344 Rats and... 12.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr408.pdf
... Pentachloronitrobenzene 326 Ethylene Oxide 327 Xylenes (Mixed) 328 Methyl Carbamate 329 1,2-Epoq~butane 330 4-Hexylresorcinol 331Malonaldehyde,SodiumSalt 332 2-Mercaptobenzothiale ...
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TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf
... Carbamate 2 6 1 Chlorobenzene 1,2-Epoxybutane 329 263 1,2-Dichloropropane 330 4-Hexylresorcinol 266 Monuron 331 Malonaldehyde,SodiumSalt 267 1,2-Propylene Oxide 332 ...
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TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf
... Blue 1 HC Blue 2 HC Red 3 HC Yellow 4 Hexachlorocyclopentadiene Hexachloroethane 4-Hexylresorcinol Hydrochlorothiazide Hydroquinone 8-Hydroxyquinoline Iodinated Glycerol Isobutene ...
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TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf
... Blue 1 HC Blue 2 HC Red 3 HC Yellow 4 Hexachlorocyclopentadiene Hexachloroethane 4-Hexylresorcinol Hydrochlorothiazide Hydroquinone 8-Hydroxyquinoline Indium Phosphide Iodinated ...
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TR-426: Corn Oil, Safflower Oil, and Tricaprylin (CASRNs. 8001... 18.8MB
https://ntp.niehs.nih.gov/go/tr426
... Ethylene Oxide Xylenes (Mixed) Methyl Carbamate 1,2-Epoxybutane 4-Hexylresorcinol Malonaldehyde, Sodium Salt 2-Mercaptobenzothiale N-Phenyl-2-naphthylamine ...
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TR-394: Acetaminophen (CASRN 103-90-2) in F344 Rats and B6C3F1Mice... 14.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr394.pdf
... 1,2-Epoxybutane 330 4-Hexylresorcinol 331 Malonaldehyde, Sodium Salt 332 2-Mercaptobenzothiale 333 N-Phenyl-2-naphthylamine 334 2-Amino-5-nitrophenol 335 C.I. Acid Orange 3 i 7 U . ...