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Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf
... It was suggested that the remaining dose might have been demethylated to ethanolamine ... cells overexpressing the Drosophila ethanolamine kinase, ethanolamine (50 to 200 µM) ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
... It is used as a chemical intermediate for anion- ethanolamine (greater than 99% pure) by ... male or female mice that received dermal applications of tri- ethanolamine for 13 weeks. ...
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RoC Background Document for Diethanolamine; March 22, 2002 1.1MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/deapub_no_appendices_508.pdf
... DEA is thought to be conserved by a mechanism that normally conserves ethanolamine, a ... presumably via the same enzymatic pathways that normally utilize ethanolamine. ...
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TOX-20: Diethanolamine (CASRN 111-42-2) 2.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox020.pdf
... Its reactions with long- chain fatty acids form neutral ethanolamine soaps (Mullins, 1978) ... reduced the level of incorporation of ethanolamine and choline into hepatic and renal ...
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TR-478: Diethanolamine (CASRN 111-42-2) in F344/N Rats and B6C3F1Mice... 10.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr478.pdf
... In most production facilities, ethylene oxide and ammonia are are reacted in a bath process that yields a crude mix- ture of ethanolamine, diethanolamine, and tri- ethanolamine. ...
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TR-586: CIMSTAR 3800 in F344/NTac Rats and B6C3F1/N Mice and... 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr586_508.pdf
... These sensitizers, irritants, or toxicants include ethanolamine and other amines, ... primarily as particulates while ethanolamine and 1-amino- CIMSTAR 3800, NTP TR 586 ...
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TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and B6C3F1Mice... 10.1MB
https://ntp.niehs.nih.gov/go/tr449
... and carcinogenesis studies of tri- ethanolamine first received public review by the ... long-chain fatty acids to form neutral ethanolamine soaps and "sweetening" of natural gas ...
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TR-091: Clonitralid (CASRN 1420-04-8) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr091.pdf
... II. MATERIALS AND METHODS A. Chemicals Technical-grade clonitralid (2 1 ,5-dichloro-4'-nitrosalicylanilide ethanolamine salt) was purchased from Chemagro Corporation, Kansas City, ...
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TOX-80: Sodium Thioglycolate (CASRN 367-51-1) Administered Dermally... 3.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox080_508.pdf
... Hair straightening products containing ammonium or ethanolamine thioglycolate or ... thioglycolate, calcium thioglycolate, ethanolamine thioglycolate, ethyl thioglycolate, ...
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RoC Profile: Nitrosamines; 15th RoC 2021 374KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrosamines.pdf
... N-Nitrosodi ethanolamine is present in most cutting fluids containing triethanolamine and sodium nitrite, at concentrations ranging from 0.02% to 3% (IARC 1978). In addition, an ...
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TR-591: TRIM VX in Wistar Han [Crl:WI (Han)] Rats and B6C3F1... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr591_508.pdf
... In addition, the concentrations of some suspected carcinogens, such as ethanolamine, have ... These sensitizers, irritants, or toxicants include ethanolamine and other amines, ...
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ICCVAM Test Method Evaluation Report: In Vitro Test Methods for... 34.8MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/invitro-2010/tmer-vol2.pdf
... Monoethanolamine 141-43-5 1 10% Solution 12.58 12 0.00 Severe 5.00 100.00 Severe 2B III NI Hagino et al. (1999)/Submitted Y. Ohno Data Monoethanolamine 141-43-5 2 10% Solution ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
... N-nitrosomethylurea see N-Nitrosamines: 15 Listings, N-Nitroso-N-methylurea N-nitrosophenylhydroxylamine, ethanolamine salt see Cupferron naphtho(1,2,3,4-def)chrysene see ...
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DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf
... was excreted unchanged. 24 The investigators proposed that the remaining compound could have been demethylated to ethanolamine and used in normal metabolic pathways. ...
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ICCVAM Report: Corrositex: An In Vitro Method for Assessing Dermal... 5.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf
... Amine 99+ 86.17 1 III III p1 p82 1-3-82069, #21 47 Ethanolamine Amine 99+ 23.88 1 II II ... 1998). No original data submitted. ethanolamine 141-43-5 23.92 23.83 2 3 . 8 8 0 . 0 6 ...
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Performance Standards for In Vitro Test Methods for Skin Corrosion 6.3MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/ps/ps044510.pdf
... 98 II II 5.2 1-(2-Aminoethyl) piperazine 140-31-8 organic base 99 II II 11.8 Ethanolamine 141-43-5 organic base 99+ II II 11.8 Sodium hydroxide 1310-73-2 inorganic base 100 II II ...
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TOX-50: Cyclohexanone Oxime 2.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox050.pdf
... passed through an ethanol (200 ml) trap for the collection of volatiles and then through 200 ml of a 7:3 (v /v) mixture of 2-methoxyethanol/ ethanolamine for ' 4 C0 2 collection. ...
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Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf
... Edwards, D.J., and Antelman, S.M. 1980. Mono amine oxidase and the metabolism of phenyl ethanolamine tyramine and octopamine. In: Mosnaim, A.D., and Wolf, M.E., Eds. Modern ...
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RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dieselexhaust_508.pdf
... Phosphatidyl ethanolamine content was lower in liver tissues of some dogs exposed for 68 months, and lung tissue phosphatidyl ethanolamine content was 90% of the mean control ...
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TR-250: Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1Mice... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr250.pdf
... Volatiles were collected in a series of two traps containing 200 ml cold ethanol. C02 was collected in a series of two traps containing 200 ml ethanolamine: methyl cellosolve ...
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ICCVAM Test Method Evaluation Report on the Applicability Domain... 16.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ad/tmer-revmay2012.pdf
... Formulation 4 100 g/L Clopyralid mono- ethanolamine salt) 1702-17-6 192.00 NA Liquid ... Formulation 4 100 g/L clopyralid mono- ethanolamine salt) 1702-17-6 192.00 NA Liquid ...
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TR-581: Cobalt Metal (CASRN 7440-48-4) in F344/N Rats and B6C3F1... 9.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr581_508.pdf
The Toxicology STudieS of cobalT MeTal (caSRN 7440-48-4) iN f344/N RaTS aNd b6c3f1/N Mice aNd Toxicology aNd caRciNogeNeSiS STudieS of cobalT MeTal iN f344/NTac RaTS aNd b6c3f1/N ...
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TR-316: Dimethylvinyl Chloride (1-Chloro-2-Methylpropene) (CASRN... 15.1MB
https://ntp.niehs.nih.gov/go/tr316
... Expired air was passed first through an ethanol-filled trap or an activated carbon trap to retain expired organic compounds and then through two con- secutive ethanolamine traps to ...
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TR-443: Oxazepam (CASRN 604-75-1) in Swiss-Webster and B6C3F1Mice... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr443.pdf
... Carbon dioxide was trapped in ethanolamine/ethylene glycol monomethyl ether (3:7). Collected urine was centrifuged at 1,000 x g t o sediment particulates, and directly injected ...
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Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
... 2,2'-(hexylamino)bis-. 721.3350 N-Nitrosodiethanolamine. 721.3360 Substituted ethanolamine. 721.3364 Aliphatic ether. 721.3374 Alkylenediolalkyl ether. 721.3380 Anilino ...
