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TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf
... Halothane anesthesia for all rats designated for biochemical interim evaluations. Necropsy ... The rats were anesthetized with halothane and intubated orally with a tracheal catheter ...
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Minutes: BSC; Sept. 17, 2002 762KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2002/september/20020917bscsummmins_508.pdf
... She said PETA would request that the NTP use halothane or halothane followed by carbon dioxide as the most humane method of euthanasia for the animals. Ms. Sweetland urged more ...
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TR-451: Nickel Oxide (CASRN 1313-99-1) in F344 Rats and B6C3F1... 27.7MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr451.pdf
... Rats and mice were anesthetized with halothane and killed by cardiac puncture the morning ... The animals were anesthetized with halothane and blood was collected by cardiac puncture ...
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Minutes: BSC; March 14, 1989 53.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1989/march/19890314bsc_minutes_508.pdf
... Exposure to halothane anesthesia results in increases in isobutane exhalation in humans, ... , H., and Roster, U. ( 1980 Isabutene formation during halothane anaesthesia in man. Br. ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... 12.5 325 Cyclohexanol 108-93-0 2634.73 26.3 2063.7 20.6 NA NA 100.18 20.6 326 Halothane 151-67-7 6138.83 31.1 5684.8 28.8 NA NA 197.39 28.8 327 20 Lithium I sulfate 10377-48-7 ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... 325 Cyclohexanol 26.3 20.6 2063.7 326 Halothane 31.1 28.8 5684.8 327 20 Lithium I ... 348 1-Propanol 96.5 89.8 5397.9 326 Halothane 31.1 28.8 5684.8 128 10 2-Propanol 167 ...
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TR-002: Trichloroethylene (CASRN 79-01-6) 19.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr002.pdf
... Pharmacol. 2 : 37-44. Price, H. L.; Dripps, R. D. (1965) General Anesthetics, II. Volatile Anesthetics: Diethyl Ether, Divinyl Ether, Chloroform, Halothane, Methoxyflurane, and ...
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TR-453: Nickel Subsulfide (CASRN 12035-72-2) in F344 Rats and... 17.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr453.pdf
... Exsanguination under halothane anesthesia Necropsy performed on all animals. Organs weighed were the brain, heart, right kidney, liver, lung, right testis, and thymus. Blood was ...
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TR-454: Nickel Sulfate Hexahydrate (CASRN 10101-97-0) in F344... 19.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr454.pdf
... Method of Sacrifice Exsanguination under halothane anesthesia Necropsy Necropsy performed on all animals. Organs weighed were brain, heart, right kidney, liver, lung, right testis, ...
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RoC Background Document: Tetrafluoroethylene; March 1999 4.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrafluoroethylene1.pdf
... Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J. Bioi. Chem. 266, ...
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TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB
https://ntp.niehs.nih.gov/go/tr371
... Toxicol. Teratol. 3:471-475. 166.Moser, V.C.; Balster, R.L. (1985)Effects of toluene, halothane and ethanol vapor on fixed- ratio performance in mice. Pharmacol. Biochem. Behav. ...
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TR-450: Tetrafluoroethylene (CASRN 116-14-3) in F344 Rats and... 21.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr450.pdf
... Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J. Biol. Chem. 266, ...
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ICCVAM Test Method Evaluation Report: In Vitro Ocular Toxicity... 5.9MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/oteval/otevalrpt.pdf
... arcade and postcapillary venules. Adult male Sprague-Dawley rats anesthetized with halothane gas and right cornea centers were treated with a silver nitrate applicator stick (75% ...
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ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... 4-Hexylresorcinol 194.3 0.064 12.4 2.83 549.9 L-Dopa 197.21 0.13 25.6 9.03 1780.8 Halothane 197.39 31.1 6138.8 28.8 5684.8 Arsenic III trioxide 197.84 0.0042 0.8 0.1 19.8 ...
