-
TR-566: Diethylamine (CASRN 109-89-7) in F344/N Rats and B6C3F1... 8.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr566.pdf
Park, NC 27709 October 2011 NTP TR 566 NIH Publication ... The Technical Report series began in 1976 with ... aromatic hydrocarbons, mineral oils, and stearic and oleic ...
-
TOX-17: Black Newsprint Inks 2.1MB
https://ntp.niehs.nih.gov/go/tox017
... ink-oil mists generated from lubricating oils and from printing inks which 10 BLACK NEWSPRINT INK, NTP TOXICITY REPORT NUMBER 17 contain mineral oil (a vehicle for carbon black). ...
-
RoC Background Document for Diethanolamine; March 22, 2002 1.1MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/deapub_no_appendices_508.pdf
... semisynthetic fluids, which consist of mineral oil, a soluble base (usually amines), ... The original report (Eisen et al. 1992) did not describe effects for specific metalworking ...
-
TR-381: d-Carvone (CASRN 2244-16-8) in B6C3F1Mice (Gavage Studies... 6.3MB
https://ntp.niehs.nih.gov/go/tr381
... Lijinsky proposed that all references to the studies in rats be deleted from the Report. ... pro- pylene glycol, fixed oils, and mineral oil (Con- densed Chemical Dictionary, 1981). ...
-
GMM-04: Genetically Modified Model Report on Pentaerythritol... 5.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/gmm_rpts/gmm04_508.pdf
... pentaerythritol triacrylate in white mineral oil (2.5 mg/mouse) painted onto the shaved ... Humans No epidemiology studies or case reports associating pen- taerythritol triacrylate ...
-
TR-484: 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/go/tr484
... Medinsky moved that under the conditions of this study, the Technical Report on ... at 25E C. It is miscible with water and soluble in mineral oil and most organic solvents. ...
-
TR-244: Polybrominated Biphenyl Mixture (Firemaster FF-1) in... 8.6MB
https://ntp.niehs.nih.gov/go/tr244
... In another study, different diets and mineral oil were used to study the PBB concentration ... and mice are described in this technical report. 15 Polybrominated Biphenyl Mixture ...
-
TR-463: D&C Yellow No. 11 (CASRN 8003-22-3) in F344 Rats (Feed... 12.5MB
https://ntp.niehs.nih.gov/go/tr463
... Dr. Russo moved that the Technical Report on D& C Yellow No. 11 be accepted with the ... ethanol, ethyl acetate, linseed oil, mineral oil, oleic acid, paraffin wax, stearic ...
-
TOX-8: D&C Yellow No. 11 (CASRN 8003-22-3) 2.1MB
https://ntp.niehs.nih.gov/go/tox008
... The Panel recommended completion of the report with consideration of the points discussed. ... lin- seed oil, mineral oil, and oleic acid; and insoluble in water (Colour Index, 1982). ...
-
TR-553: Photococarcinogenesis Study of Aloe Vera[CASRN 481-72... 6.7MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr553.pdf
... Reports on analyses performed in support of the study on the effect of Aloe vera on the ... A A B B Mineral Oil 65/75 Glycerin 96% Carbopol 981 (2% Soln.) Ceteryl Alcohol Penreco/...
-
Nomination Background: Trimethylolpropane triacrylate (CASRN... 508KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/tmtpa_508.pdf
... 5% solution of trimethylolpropane triacrylate in mineral oil 2 times per week for 5 weeks. ... C. Prechronic 1. Epidemiological Evidence/Case Reports The case reports concern the skin ...
-
TR-433: Tricresyl Phosphate (CASRN 1330-78-5) in F344/N Rats... 24.1MB
https://ntp.niehs.nih.gov/go/tr433
... more toxic with corn oil as a vehicle than with mineral oil as a vehicle. Dr. van Zwieten moved that, the Technical Report on tricresyl phosphate be accepted with the revision ...
-
Minutes: BSC TRRS; June 22, 1993 561KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/trrs/1993/june/trrs22june1993mins_508.pdf
... more toxic with corn oil as a vehicle than with mineral oil as a vehicle. Dr. van Zwieten moved that the Technical Report on tricresyl phosphate be accepted with the revisions ...
-
TR-310: Marine Diesel Fuel (NO CAS) and JP-5 Navy Fuel (CASRN... 10.1MB
https://ntp.niehs.nih.gov/go/tr310
... National Technical Informahion Service Report, prepared for the U.S.Department of Energy ... potential of twelve re- fined mineral oils following long-term topical application. ...
-
RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf
... The pitfalls of hair analysis for toxicants in clinical practice: three case reports. ... D.H. J.M. Benoit, and H.A. Tyroler. 1970. An epidemiologic study of an oil mist exposure. ...
-
Nomination Background: 1,3,5-Triazine-1,3,5(2H,4H,6H)-triethanol... 103KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/triazinetriethanol_508.pdf
from TZT-like biocides, and that inhalation of oil mists, themselves, may be toxic. ... guidelines specify that each company's report of a chemical represents production of ...
-
Nomination Background: alpha-Pinene (CASRN: 80-56-8) 1.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/turpentine_508.pdf
... Acute Exposure For the purpose of this report, acute exposures are defined as single or ... induced by carbon tetrachloride (CCl 4 in mineral oil, i.p.) (Greenwel and Rojkind, 1997). ...
-
McFarland et al: Non-animal replacement methods for human vaccine... 1019KB
https://ntp.niehs.nih.gov/iccvam/meetings/leptovaccwksp-2012/refs/mcfarlandetal2011-508.pdf
Procedia in Vaccinology 5 ( 2011 ) 16 - 32 NICEATM-ICCVAM # ... This report addresses methods and strategies identified by ... may contain mineral oil or other more complex adjuvants. ...
-
Kulpa-Eddy et al: Non-animal replacement methods for veterinary... 1.1MB
https://ntp.niehs.nih.gov/iccvam/meetings/leptovaccwksp-2012/refs/kulpa-eddyetal2011-508.pdf
Procedia in Vaccinology 5 ( 2011 ) 60 - 83 NICEATM-ICCVAM # ... participants and are reported in a series of six reports. ... However, many typically use adjuvants such as mineral oil ...
-
RoC Profile: Trichloroethylene; 15th RoC 2021 237KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/trichloroethylene.pdf
... Report on Carcinogens, Fifteenth Edition For definitions of ... et al. 2008, Bahr et al. 2011, Lip- worth et al. 2011, ... effects of solvents and mineral
oils on cancer incidence and ...
-
Nomination Background: Metal working fluids (Clearedge 6584)... 570KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/mwfs_508.pdf
... Sulfochlorinated mineral oils with fatty oils added are good for heavy-duty, slow-speed operations [CRC 1985]. ILMA [1996] reports that current formulations have reduced or ...
-
RoC Monograph: Trichloroethylene; January 2015 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/finaltce_508.pdf
... processing workers (Bahr et al. 2011; Ritz 1999) did not report on kidney cancer and exposure ... from lifestyle factors and mineral oils, the major co- exposure in this ...
-
TR-568: Photocarcinogenesis Studies of Retinoic Acid and Retinyl... 18.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr568_508.pdf
... PANEL COMMENTS On January 26, 2011, the draft Technical Report on the photococarcinogenicity ... glycol = isopropyl alcohol > mineral oil > diisopropyl adipate > ...
-
Nomination Background: Methyl soyate (CASRN: 67784-80-9) 128KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/methylsoyate_508.pdf
... The OSHA permissible exposure limit of 5 mg/m 3 for oil mists may apply to some products ... Data: No epidemiological studies or case reports investigating the association of exposure ...
-
TR-569: Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine... 7.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr569_508.pdf
... REVIEW PANEL COMMENTS On April 5, 2011, the draft Technical Report on the toxicology and ... insoluble in soy bean oil and mineral
oil (Merck, 2006d; PDR, 2007c). ...
-
Nomination Background: Linalool (CASRN: 78-70-6) 190KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/linalool_508.pdf
... most aliphatic and aromatic esters, mineral oil, and chlorinated solvents Technical ... EVIDENCE FOR POSSIBLE CARCINOGENIC ACTIVITY Human Data: No epidemiological or case reports ...
-
TR-591: TRIM VX in Wistar Han [Crl:WI (Han)] Rats and B6C3F1... 7.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr591_508.pdf
... Mineral oils: Untreated and mildly- treated oils (group 1). Highly-refined oils ... National Institutes of Health; 2011. Technical Report Series No. 566. NIH Publication No. ...
-
Classen: Case study of development, validation, and acceptance... 398KB
https://ntp.niehs.nih.gov/iccvam/meetings/leptovaccwksp-2012/refs/claasen2011-508.pdf
... Procedia in Vaccinology 5 ( 2011 ) 175 - 183 2.1. Antigen ... poultry vaccines are adjuvanted with mineral oils. ... testing of vaccines: the report and recommendations of ...
-
TR-586: CIMSTAR 3800 in F344/NTac Rats and B6C3F1/N Mice and... 2.8MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr586_508.pdf
... Vols. 1-42, Suppl. 7. Mineral oils: Untreated and mildly-treated oils (group 1). ... National Institutes of Health; 2011. Technical Report Series No. 566. NIH Publication No. ...
-
Peer Review Report: Technical Reports Peer Review Panel Meeting... 254KB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2016/february/panel_report20160216_508.pdf
... He noted a discrepancy of NTP's analysis of mineral oil ... systemic effects than what is currently in the draft report. ... Baarlen J, Van Der Valk PD. 2011. Toxic alveolitis after ...
-
Peer Review Report: RoC Peer Review; Aug. 12, 2014 198KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2014/august/sep_report20140812_508.pdf
... B, Stewart P, De Roos AJ, Schenk M, Lynch CF, et al. 2011a. ... Am J Ind Med 57(4): 412-424. 28 Peer-Review Report - August ... effects of solvents and mineral oils on cancer incidence and ...
-
Nomination Background: 2,5-Dimercapto-1,3,4-thiadiazole (CASRN... 758KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmct_508.pdf
... The induction phase was done with 15% w/v CUVAN ® 826 in mineral oil; the challenge was ... possess too many constituent groups to merit any toxicity discussion in this report. ...
-
TR-576: Trimethylolpropane Triacrylate (Technical Grade) (CASRN... 6.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr576_508.pdf
... 2012, the draft Technical Report on the toxicology and ... Toxic Substances Control Act (TSCA) inventory (USEPA, 2011). ... or in acetone or mineral oil to the interscapular ...
-
TOX-103: Toxicity Studies of Select Ionic Liquids (1-Ethyl-3... 4.7MB
https://ntp.niehs.nih.gov/go/tox103
... Toxicity Report 103. Acknowledgments This work was supported ... HHSN316201200054W, HHSN273201100001C, N01-ES-45517, ... (Lot S37784), Nujol Mineral Oil ......
-
Nomination Background: Methylolurea (CASRN: 1000-82-4) 497KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/methylolurea_508.pdf
... 3M. 1991. Product toxicity summary sheet. 3M microcapsules mineral Oil/32 micron. ... U.S. EPA. 1983. Twelfth report of the Interagency Testing Committee to the Administrator; ...
-
ICCVAM Biennial Progress Report 2010-2011 11.9MB
https://ntp.niehs.nih.gov/iccvam/docs/annrpt/biennial2012-508.pdf
Committee on the Validation of Alternative Methods Biennial Progress Report 2010 -2011 A bout the Inter agency Coor dinating Committee on the Validation of Alter native ...
-
P14: Individual Animal Pathology Data for Rats (20303-05) 1.5MB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20303_tables/05p14.pdf
4: INDIVIDUAL ANIMAL PATHOLOGY DATA Date Report Requested: 12/12/2011 Test Type: CHRONIC Vinylidene chloride Time Report Requested: 09:47:55 Route: RESPIRATORY EXPOSURE WHOLE BODY ...
-
Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 1.2MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_byroute.pdf
NTP Historical Controls Report By Route and Vehicle MICE May 2011 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies ...
-
Historical Controls: Pathology Tables by Route/Vehicle for Fischer... 1.2MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_byroute.pdf
By Route and Vehicle F 344/N RATS May 2011 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the ...
-
P10: Statistical Analysis of Nonneoplastic Lesions for Rats ... 346KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20303_tables/05p10.pdf
0: STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS Date Report Requested: 12/12/2011 Test Type: CHRONIC Vinylidene chloride Time Report Requested: 09:47:55 Route: RESPIRATORY ...
-
P10: Statistical Analysis of Nonneoplastic Lesions for Rats ... 496KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20107_tables/03p10.pdf
P10: STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS Date Report Requested: 02/28/2011 Test Type: CHRONIC N,N-Dimethyl-p-toluidine Time Report Requested: 11:17:44 Route: GAVAGE CAS ...
-
P10: Statistical Analysis of Nonneoplastic Lesions for Mice ... 437KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20107_tables/04p10.pdf
0: STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS Date Report Requested: 03/10/2011 Test Type: CHRONIC N,N-Dimethyl-p-toluidine Time Report Requested: 11:42:39 Route: GAVAGE CAS ...
-
P04: Neoplasms by Individual Animal for Rats (20303-05) 760KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20303_tables/05p04.pdf
4: NEOPLASMS BY INDIVIDUAL ANIMAL Date Report Requested: 12/12/2011 Test Type: CHRONIC Vinylidene chloride Time Report Requested: 09:47:50 Route: RESPIRATORY EXPOSURE WHOLE BODY ...
-
P10: Statistical Analysis of Nonneoplastic Lesions for Rats ... 394KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/99031_tables/03p10.pdf
0: STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS Date Report Requested: 01/17/2011 Test Type: CHRONIC Ginkgo biloba extract Time Report Requested: 12:22:19 Route: GAVAGE CAS ...
-
Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf
NTP Historical Controls Report All Routes and Vehicles MICE May 2011 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The ...
-
Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf
All Routes and Vehicles F 344/N RATS May 2011 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the ...
-
P10: Statistical Analysis of Nonneoplastic Lesions for Rats ... 348KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20009_tables/03p10.pdf
0: STATISTICAL ANALYSIS OF NON-NEOPLASTIC LESIONS Date Report Requested: 05/27/2011 Test Type: CHRONIC beta-Picoline Time Report Requested: 10:09:56 Route: DOSED WATER CAS Number: ...
-
P08: Statistical Analysis of Primary Tumors for Rats (20303-05... 244KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20303_tables/05p08.pdf
8: STATISTICAL ANALYSIS OF PRIMARY TUMORS Date Report Requested: 12/12/2011 Test Type: CHRONIC Vinylidene chloride Time Report Requested: 09:47:55 Route: RESPIRATORY EXPOSURE WHOLE ...
-
P09: Nonneoplastic Lesions by Individual Animal for Rats (20303... 751KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20303_tables/05p09.pdf
9: NON-NEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL Date Report Requested: 12/12/2011 Test Type: CHRONIC Vinylidene chloride Time Report Requested: 09:47:55 Route: RESPIRATORY EXPOSURE ...
-
P09: Nonneoplastic Lesions by Individual Animal for Rats (20107... 821KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20107_tables/03p09.pdf
P09: NON-NEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL Date Report Requested: 02/28/2011 Test Type: CHRONIC N,N-Dimethyl-p-toluidine Time Report Requested: 11:17:44 Route: GAVAGE CAS ...