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Abstract for RACB90029 59KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb90029
9abs Abstract for RACB90029 Reproductive Toxicity of Iowa Pesticide/Fertilizer Mixture in CD-1 Swiss Mice CASRN: PESTFERTMIX3 Report Date: August 1992 Abstract The following ...
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Abstract for TOX-36 63KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox036
6abs Abstract for TOX-36 Toxicity Studies of Pesticide/Fertilizer Mixtures Administered in Drinking Water to F344/N Rats and B6C3F1 Mice Report Date: July 1993 Full Report PDF ...
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Abstract for TER91032 60KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91032
2abs Abstract for TER91032 Developmental Toxicology of Iowa Pesticide/Fertilizer Mixture in Sprague Dawley (CD) Rats CASRN: PestFertMix3 Report Date: August 1992 Abstract The ...
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RoC Background Document: Nickel Compounds; Dec. 2-3, 1998 6.7MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/nickelcompds1_oneapp_508.pdf
NICKEL COMPOUNDS FINAL MARCH 1999 Prepared for the December 2-3, 1998, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by ...
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TOX-36: Pesticide/Fertilizer Mixtures 5.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox036.pdf
6 N T P Technical Report on Toxicity Studies of Pesticide/Fertilizer Mixtures Administered in Drinking Water to F344/N Rats and B6C3F, Mice National Toxicology Program Post Office ...
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RoC Background Document: Cadmium; Oct. 30-31, 1997 13.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cadmium_508.pdf
CADMIUM FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by Integrated ...
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RoC Profile: Nitrosamines; 15th RoC 2021 374KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrosamines.pdf
N-Nitrosamines: 15 Listings R 1 N R 2 N O Generic N-nitrosamine structure N-Nitrosamines are a class of chemical compounds with the general structure shown above. The essential ...
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RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf
FINAL Report on Carcinogens Background Document for Lead and Lead Compounds May 8, 2003 Prepared for the: U.S. Department of Health and Human Services Public Health Service ...
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RoC Background Document: Beryllium Compounds; Dec. 16-17, 1999 5.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/be_no_appendices_508.pdf
... ::e; I 13J 240 240 48J 240 240 Total 1518 29:li ~ cl!s::rite:i in tre 1eXI. this is a pan oi a lag;rstu:i,> of the caJtin::g=ni:ity of combired e:xp:lSwe.s of rat:s to Be I ...
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RoC Profile: Lead and Lead Compounds; 15th RoC 2021 190KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/lead.pdf
Lead and Lead Compounds CAS No. 7439-92-1 (Lead) No separate CAS No. assigned for lead compounds as a class Reasonably anticipated to be human carcinogens First listed in the ...
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Abstract for TR-431 70KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr431
1abs Abstract for TR-431 Toxicology and Carcinogenesis Studies of Benzyl Acetate in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 140-11-4 Chemical Formula: C9H10O2 Molecular ...
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TR-495: Sodium Nitrite (CASRN 7632-00-0) IN F344/N Rats and B6C3F1Mice... 16.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr495.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM NITRITE (CAS NO. 7632-00-0) IN F344/N RATS AND B6C3F 1 MICE (DRINKING WATER STUDIES) NATIONAL ...
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Comment: Meat-related exposures (ORoC3); Shalene McNeill, The... 69KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill_3oroc20161007.pdf
SUMMARY OF OBSERVATIONS Data from Kazerouni and co---workers (2001) indicates that pan and ... increased exposure to HCAs from pan---frying is not limited to red and processed meat. ...
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Comment: Meat-related exposures (OHAT4); Shalene McNeill, The... 70KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill_4ohat20161007.pdf
SUMMARY OF OBSERVATIONS Data from Kazerouni and co---workers (2001) indicates that pan and ... increased exposure to HCAs from pan---frying is not limited to red and processed meat. ...
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Public Comment: Neonicotinoid pesticides; Eric Chivian, Table... 38KB
https://ntp.niehs.nih.gov/ntp/ohat/publiccomms/2016/attachment.pdf
Table 1: 2011 Summary of Groundwater Sample Results for the Monitoring Well Project Compound Number of Detects Detect Range (parts per billion) Groundwater Enforcement Standard ...
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RoC Profile: Cadmium and Cadmium Compounds; 15th RoC 2021 162KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cadmium.pdf
Cadmium and Cadmium Compounds CAS No. 7440-43-9 (Cadmium) No separate CAS No. assigned for cadmium compounds as a class Known to be human carcinogens First listed in the First ...
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Comment: Meat-related exposures; Jane Pouzou, Solenne Costard... 945KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/pouzou_costard_zagmutt20161011.pdf
... Table 1. 19 pan-fried beef (300C/6min) pan-fried beef (150- 180C/10 min) pan-fried beef scrapings barbecued beef barbecued chicken Salmon (grilled) Salted fish (grilled) IQ 260±43 ...
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TR-431: Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1Mice... 15.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr431.pdf
... kidney, larynx, liver, lung, nose, ovary, pan-, parathyroid gland, pituitary gland, ... 1 (2%) (50) (49) Cyst Hemorrhage 7 (14%) Pan, d i s t a l i s ,hyperplasia, focal Pan, ...
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TOX-74: Cellulose Insulation 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox074_rev.pdf
... It can also be installed on complex surfaces and substrates (e.g., barrel vaults, corrugated decks, concrete "T"s or pans, flat surfaces, wood, concrete, metal, sheetrock, plaster, ...
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Adrenal glands - Necrosis - Nonneoplastic Lesion Atlas 294KB
https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/adrenal-gland/Necrosis
References: Chen-Pan C, Pan I-J, Yamamoto Y, Sakogawa T, Yamada J, Hayashi Y. 1999. Prompt recovery of damaged adrenal medulla induced by salinomycin. Toxicol Pathol 27:563-572. ...
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Adrenal Gland - Necrosis 512KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/endocrine/adrenal/necrosis/adrenal-gland-necrosis-pdf_508.pdf
... References: Chen-Pan C, Pan I-J, Yamamoto Y, Sakogawa T, Yamada J, Hayashi Y. 1999. Prompt recovery of damaged adrenal medulla induced by salinomycin. Toxicol Pathol 27:563-572. ...
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RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf
Cobalt and Cobalt CoMpounds that Release Cobalt ions in ViVo ROC MONOGRAPH 06 APRIL 2016 Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In ...
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Topics Under Consideration 60KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/nominated
In the U.S., the average total daily processed meat intake is estimated to be 23 g. Cooking meat at high temperatures refers to cooking methods including grilling and pan frying as ...
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TR-561: Tetralin (CASRN 119-64-2) in F344/N Rats and B6C3F1 Mice... 13.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr561.pdf
... During the first 4 weeks of exposure, dark-stained urine was observed in the catch pans of ... Dark-stained urine was observed in the catch pans of mice exposed to 30, 60, or 120 ppm ...
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Background Document for Selected Heterocyclic Amines: PhIP, MeIQ... 3.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/hcaspub_508.pdf
... In addition, the extent to which pan residue and gravy were consumed affected the amount ... in hamburger patties and pan residues, with a greater effect noted in the pan residues. ...
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National Institute of Environmental Health Sciences: Jennifer... 156KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/jennifer
... S, Xiao N, Huang CC, Boyer P, Chan DD, Pan Q, Gong H, Taylor J, Choi D, Rashid A, ... S, Xiao N, Huang CC, Boyer P, Chan DD, Pan Q, Gong H, Taylor J, Choi D, Rashid A, ...
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Presentation: Cobalt and Certain Cobalt Compounds: Properties... 908KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/humanexposure_508.pdf
Sanford C. Garner, PhD Integrated Laboratory Systems, Inc. Contractor supporting the ORoC National Institute of Environmental Health Sciences July 22, 2015 Properties and Human ...
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Presenter Biosketches: Sept. 2010 ICCVAM Workshop on Vaccine... 163KB
https://ntp.niehs.nih.gov/iccvam/meetings/biologicswksp-2010/wkshpbiosketch.pdf
He has published more than 15 papers in his field and cooperated with the World Health Organization and the Pan American Health Organization as a Temporary Advisor; with the ...
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Recombinant Monoclonal Antibodies: An Indispensable Research... 2.6MB
https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2020/20200121-iccvam-cop-solache-508.pdf
... of Neuro-2a (Mouse Human astrocytoma tissue labelling Pan Trkwith abl81560 neuroblastoma cells) cells labelling Pan Trkwith abl81560 Pan-Trk immunohistochemistry is an ...
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Abstract for TOX-74 66KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox074
4abs Abstract for TOX-74 Toxicity Study Report on the Atmospheric Characterization, Particle Size, Chemical Composition, and Workplace Exposure Assessment of Cellulose Insulation ...
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Abstract for TER90031 59KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter90031
1abs Abstract for TER90031 Developmental Toxicology of California Pesticide/Fertilizer Mixture in Sprague Dawley (CD) Rats CASRN: PestFertMix2 Report Date: February 1992 Abstract ...
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TR-365: Pentaerythritol Tetranitrate (CASRN 78-11-5) with 80D... 22.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr365.pdf
No. 365 ("'l /<~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF PENTAERYTHRITOL TETRANITRATE (CAS NO. 78-11-5) WITH 80% o-LACTOSE MONOHYDRATE (PETN, NF) IN F344/N RATS AND B6C3FI MICE ...
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CERHR Update on the Reproductive and Developmental Toxicity of... 4.5MB
https://ntp.niehs.nih.gov/ntp/ohat/phthalates/dehp/dehp-monograph.pdf
... CERHR.monograph,.which.includes.the.NTP. brief.on.the.chemical.evaluated,.the.expert.pan- el. report,. and. public. comments. on. the. expert. panel.report..The.NTP-CERHR.monogr...
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RoC Profile: Acrylamide; 15th RoC 2021 154KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/acrylamide.pdf
... A small cohort study of U.S. workers (mostly male) found statistically nonsignificant in- creases in the risks for cancers of the digestive system, including pan- creatic cancer ...
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RoC Profile: 1-Bromopropane; 15th RoC 2021 194KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/bromopropane.pdf
... of the abdominal cavity and pan- creatic islet tumors in males and skin tumors (squamous-cell pap- illoma, keratoacanthoma, and basal-cell adenoma or carcinoma) in females. ...
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RoC Profile: Nitromethane; 15th RoC 2021 136KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitromethane.pdf
Nitromethane CAS No. 75-52-5 Reasonably anticipated to be a human carcinogen First listed in the Eleventh Report on Carcinogens (2004) O 2 N - CH 3 Carcinogenicity Nitromethane is ...
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Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf
... meats. 8-10 HAAs are also present in pan- fried residues used for gravies 11,12 and ... methods of high-temperature cooking (pan-frying, broiling, and barbecuing/grilling) ...
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RoC Profile: Heterocyclic Amines (Selected); 15th RoC 2021 184KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/heterocyclicamines.pdf
... Pan residues usually contain higher HCA concentrations than the meat itself; therefore, ... 9 ng/g, and very-well-done oven-broiled or pan- fried skinless, boneless chicken breasts ...
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Minutes: BSC; March 27, 1984 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf
... They were Drs . Thomas C . Pan el meeting on March 23 in Washington, D .C . Jones, Harvard ; Richard Kociba, Dow Chemical ; David Kotelchuck, United ' ; and Electrical, Radio and ...
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TOX-81: α-Pinene (CASRN 80-56-8) Administered by Inhalation... 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox081_508.pdf
... concentrations could be maintained throughout the chamber with the catch pans in place. ... weekly Cageboard Untreated paper cage pan liner (Shepherd Specialty Papers, ...
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Abstract for TR-561 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr561
... During the first 4 weeks of exposure, dark-stained urine was observed in the catch pans of ... Dark;-stained urine was observed in the catch pans of mice exposed to 30, 60, or 120 ppm ...
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Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf
... Single dose/2 yr Negative (Gilman and Ruckerbauer 1962) Cobalt oxide Hamster Syrian Golden (M) Inhalation Lifespan/lifes pan Negative (Wehner et al. 1977) Cobalt sulfide Rat ...
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Comment: Meat-related exposures, Shalene McNeill, The Beef Checkoff... 57KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill20180911-1.pdf
On 9/11/18, 8:29 AM, "NTP Website" <ntpweb-noreply@ntp.niehs.nih.gov> wrote: The following comments have been submitted to the Office of the Report on Carcinogens. Our record of ...
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RoC Profile: Diazoaminobenzene; 15th RoC 2021 129KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diazoaminobenzene.pdf
Diazoaminobenzene CAS No. 136-35-6 Reasonably anticipated to be a human carcinogen First listed in the Eleventh Report on Carcinogens (2004) Also known as 1,3-diphenyltriazene N N ...
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TR-560: Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1... 7.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr560.pdf
... and mice; pancreatic islets and exocrine pan- creas of female rats; and clitoral gland, ... induce these neoplasms, but the mouse pan- creatic islet $-cells express the androgen ...
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TOX-39: Cadmium Oxide (CASRN 1306-19-0) 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox039.pdf
39 NTP Technical Report on Toxicity Studies of Cadmium Oxide (CAS No. 1306-19-0) Administered by Inhalation to F344/N Rats and B6C3F Mice 1 June K. Dunnick, Ph.D., Study Scientist ...
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RoC Background Document for Nitromethane; March 25, 2002 1.2MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/nmpub_no_appendices_508.pdf
FINAL Report on Carcinogens Background Document for Nitromethane March 25, 2002 Prepared for the: U.S. Department of Health and Human Services Public Health Service National ...
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Comment: BSC to Strengthen and Broaden the NTP Efforts; Olga... 369KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/february/publiccomm/naidenko20210126_bsc_508.pdf
January 26, 2021 Comments submitted for the National Toxicology Program February 2, 2021, Board of Scientific Counselors meeting The Environmental Working Group, or EWG, a ...
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RoC Profile: Aflatoxins; 15th RoC 2021 135KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/aflatoxins.pdf
... In addition, kidney (renal-cell) and colon tu- mors occurred in rats, benign lung tumors (adenoma) in mice, and tumors of the liver, bone (osteogenic sarcoma), gallbladder, and pan...
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RoC Profile: Beryllium and Beryllium Compounds; 15th RoC 2021 149KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/berylliumandberylliumcompounds.pdf
Beryllium and Beryllium Compounds CAS No. 7440-41-7 (Beryllium) No separate CAS No. assigned for beryllium compounds as a class Known to be human carcinogens First listed in the ...