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TR-313: Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro... 13.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr313.pdf
cyclo buta[cd]pentalene) (CAS NO. 2385-85-5) IN F344/N RATS (FEED STUDIES) U.S. ... Mirex, NTP TR 313 NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENl~SIS STUDIES OF ...
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RoC Profile: Mirex; 15th RoC 2021 138KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/mirex.pdf
Mirex CAS No. 2385-85-5 Reasonably anticipated to be a human carcinogen First listed in the Second Annual Report on Carcinogens (1981) Also known as 1,1a,2,2,3,3a,4,5,5,5a,5b,6-dod...
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Abstract for TR-313 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr313
Studies of Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene) in F344/N Rats (Feed Studies) CASRN: 2385-85-5 Chemical ...
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Target Organs and Levels of Evidence for TR-313 58KB
https://ntp.niehs.nih.gov/data/tr/300s/tr313levels
Toxicology and Carcinogenesis Studies of Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene) (CASRN 2385-85-5) in F344/N Rats (Feed ...
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Minutes: BSC TRRS; March 4, 1987 864KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1987/mar/87mar04trrsmins_508.pdf
Gavage 7 t h i azole M irex 2385 -85-5 Feed 9 N-Phenyl-2- Feed 11 Napthyl ami ... o f a number o f p o i n t s be incorporated i n t o the r e p o r t . - Mirex. Dr. ...
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NTP Monograph on Health Effects of Low-Level Lead Appendix E... 2.5MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixe_final_508.pdf
other pollutants (p,p'-DDE, HCB, PCBs, mirex, mercury) Binary Logistic Regression ... AP. 2005. Relationship of lead, mercury, mirex, dichlorodiphenyldichloroethylene, ...
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RoC Profile: Kepone; 15th RoC 2021 129KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/kepone.pdf
... of another insecticide, mirex (IARC 1979). Investigators have detected chlordecone in soil at a concentration of 0.02 μg/g of soil 12 years after mirex was ap- plied at the rate ...
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Appendix G; 15th RoC 2021 73KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf
... (C.I. direct black 38) see Benzidine and Dyes Metabolized to Benzidine 2385-85-5 see Mirex 2425-06-1 see Captafol 2429-74-5 (C.I. direct blue 15) see 3,3'-Dimethoxybenzidin...
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Listed Substances; 15th RoC 2021 76KB
https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf
...ro-N-Nitrosoguanidine (see N-Nitrosamines: 15 Listings) Metronidazole Michler's Ketone Mirex Naphthalene Nickel, Metallic (see Nickel Compounds and Metallic Nickel) ...
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RoC Profile: Hexachlorobenzene; 15th RoC 2021 155KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/hexachlorobenzene.pdf
... hexachlorobenzene, and Mirex among male Lake Ontario sportfish ... between local fish consumption and DDE, mirex, and HCB concentrations in the breast milk ...
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TR-437: Hexachlorocyclopentadiene (CASRN 77-47-4) in F344/N Rats... 15.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr437.pdf
... such as heptachlor,chlordane,aldrin,dieldrin,endrin,and mirex (Bell et al., 1 9 7 9 ) . ... (chlordane, aldrin, dieldrin, heptachlor, mirex, endosulfan, and pentac) (Bell et al., ...
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Minutes: BSC; April 17, 1996 335KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1996/april/19960417_bsc_508.pdf
... Tennant showed results with the TG.AC for three chemicals which were nonmutagenic carcinogens in NTP bioassays. For two, o-benzyl-p-chlorophenol and Mirex, positive results were ...
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Minutes: BSC; Feb. 5, 1998 713KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf
... a mutagenic transspecies human carcinogen, and mirex, a nonmutagenic carcinogen. Dr. ... pentachlorophenol, mirex, phenolphthalein, ethyl acrylate, and ethylene thiourea. ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
... Report on Carcinogens, Fifteenth Edition 1,1a,2,2,3,3a,4,5,5,5a,5b,6-dodecachlorooctahydro-1,3,4-metheno- lH-cyclobuta(cd)pentalene see Mirex Dowicide EC-7 see Pentachlorophenol ...
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Appendices A-G; 15th RoC 2021 448KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf
... lH-cyclobuta(cd)pentalene see Mirex Dowicide EC-7 see Pentachlorophenol and ... and Dyes Metabolized to Benzidine 2385-85-5 see Mirex 2425-06-1 see Captafol ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-313 03/04/87 Mirex 2385-85-5 P Clear Evidence P Clear Evidence NT Chemical Not Tested in Species/Sex NT ...
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TR-392: Chlorinated Water (CASRNs. 7782-50-5 and 7681-52-9) and... 75.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr392.pdf
... (NTP, 1990b), Mirex (NTP, 1990a), and tris(2-chloroethyl) phosphate, (NTP, 1991b). ... Toxicology and carcinogenesis Studies of Mirex (CAS No. 2385-85-5) in F344/N Rats (Feed ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... 4.00E+06 - 4.00E+01 1.00E+01 - 1.00E-04 7.03E-05 - 7.03E-10 > 95% Sigma Powder Mirex 2385-85-5 pesticide environmental contaminant 4.00E+07 - 4.00E+02 1.00E+02 - 1.00E-03 ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... 4.00E+06 - 4.00E+01 1.00E+01 - 1.00E-04 7.03E-05 - 7.03E-10 > 95% Sigma Powder Mirex 2385-85-5 pesticide environmental contaminant 4.00E+07 - 4.00E+02 1.00E+02 - 1.00E-03 ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... and Carcinogenesis Studies of Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene) (CASRN 2385-85-5) in F344/N Rats (Feed Studies) ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... and Carcinogenesis Studies of Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene) (CASRN 2385-85-5) in F344/N Rats (Feed Studies) ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... and Carcinogenesis Studies of Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene) (CASRN 2385-85-5) in F344/N Rats (Feed Studies) ...
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TR-409: Quercetin (CASRN 117-39-5) in F344 Rats (Feed Studies... 9.6MB
https://ntp.niehs.nih.gov/go/tr409
... P ~ 3 4 1 + a-Methylbenzyl Alcohol 9" Mirex a Monuron Nitrilotriacetic Acid CH2COOH I ... Aldrin Heptachlor epoxide DDE DDD DDT HCB Mirex Methoxychloj Dieldrin' Endrin Telodrin ...
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NTP Monograph on Health Effects of Low-Level Lead Appendices... 6.8MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/appendicesathrue_final_508.pdf
... PCB congeners, aldrin, β- HCH, DDE, DDT, Mirex, Hexachlorobenzene, Chlordane, Cis- ... other pollutants (p,p'-DDE, HCB, PCBs, mirex, mercury) Binary Logistic Regression ...
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Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... Y 2G (avian) Being tested in vivo by EPA, but not considered as it is highly toxic Mirex 2385-85-5 Hydrocarbon (Halogenated) Flame Retardant, Pesticide - - ER- ER-/AR- AR- Does not ...
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TOX-103: Select Ionic Liquids (1-Ethyl-3-Methylimidazolium Chloride... 4.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox103_508.pdf
... DDD a <0.01 1 DDT a <0.01 1 HCB a <0.01 1 Mirex a <0.01 1 Methoxychlor a <0.05 1 Dieldrin ... <0.01 - 4 DDT a <0.01 - 4 HCB a <0.01 - 4 Mirex a <0.01 - 4 Methoxychlor a <0.05 - 4 ...
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DART-07: Prenatal Development Studies of 2-((1-(4-Phenoxyphenoxy... 1.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/dart/dart07_508.pdf
... DDD b <0.01 1 DDT b <0.01 1 HCB b <0.01 1 Mirex b <0.01 1 Methoxychlor b <0.05 1 Dieldrin ... DDE a <0.01 1 DDD a <0.01 1 DDT a <0.01 1 Mirex a <0.01 1 Methoxychlor a <0.01 1 Dieldrin ...
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TOX-3: Acetone (CASRN 67-64-1) 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox003.pdf
... J. 231:151-155. 51. Hewitt, L.A.; Ayotte, P.; Plaa, G.L. (1986) Modifications in rat hepatobiliary function fol- lowing treatment with acetone, 2-butanone, 2- hexanone, mirex, or ...
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TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox077_508.pdf
... Epoxide a <0.01 - 1 DDE a <0.01 - 1 DDD a <0.01 - 1 DDT a <0.01 - 1 HCB a <0.01 - 1 Mirex a <0.01 - 1 Methoxychlor a <0.05 - 1 Dieldrin a <0.01 - 1 Endrin a <0.01 - 1 ...
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TR-350: Tribromomethane (Bromoform) (CASRN 75-25-2) in F344/N... 11.8MB
https://ntp.niehs.nih.gov/go/tr350
... of chloroform induced hepato- and nephrotoxicity by mirex and Kepone. Toxicol. Appl. ... (a) DDE ( 0 ) DDD (a) DDT (a) HCB (a) Mirex (a) Methoxychlor (p) Dieldrin (a) Endrin ...
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NTP Monograph on Health Effects of Low-Level Lead Appendix A... 2.5MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixa_final_508.pdf
... examined with 10 motor tasks Also measured PCB congeners, aldrin, β- HCH, DDE, DDT, Mirex, Hexachlorobenzene, Chlordane, Cis- Nonachlor, Trans- Nonachlor, Oxychlordane, and Hg ...
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DART-01: Prenatal Development Studies of Tris(chloropropyl) Phosphate... 937KB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart01_508.pdf
... 1 Heptachlor Epoxide <0.01 - 1 DDE <0.01 - 1 DDD <0.01 - 1 DDT <0.01 - 1 HCB <0.01 - 1 Mirex <0.01 - 1 Methoxychlor <0.05 - 1 Dieldrin <0.01 - 1 Endrin <0.01 - 1 Telodrin <0.01 - 1 ...
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DART-02: Prenatal Development Studies of 4-Methylcyclohexanemethanol... 1.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart02_508.pdf
... <0.01 1 Heptachlor Epoxide <0.01 1 DDE <0.01 1 DDD <0.01 1 DDT <0.01 1 HCB <0.01 1 Mirex <0.01 1 Methoxychlor <0.05 1 Dieldrin <0.01 1 Endrin <0.01 1 Telodrin <0.01 1 ...
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DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf
... 2 Heptachlor Epoxide <0.01 - 2 DDE <0.01 - 2 DDD <0.01 - 2 DDT <0.01 - 2 HCB <0.01 - 2 Mirex <0.01 - 2 Methoxychlor <0.05 - 2 Dieldrin <0.01 - 2 Endrin <0.01 - 2 Telodrin <0.01 - 2 ...
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IMM-01: Dermal Hypersensitivity and Irritancy Studies of 4-Methylcyclo... 969KB
https://ntp.niehs.nih.gov/ntp/htdocs/imm/imm001_508.pdf
... 3 Heptachlor Epoxide <0.01 - 3 DDE <0.01 - 3 DDD <0.01 - 3 DDT <0.01 - 3 HCB <0.01 - 3 Mirex <0.01 - 3 Methoxychlor <0.05 - 3 Dieldrin <0.01 - 3 Endrin <0.01 - 3 Telodrin <0.01 - 3 ...
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TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf
... Aldrin Heptachlor epoxide IIDE DDD DDT HCB Mirex Methoxychlor Dieldrin Endrin Telodrin ... (Inhalation) 312 nButyl Chloride 313 Mirex 314 Methyl Methacrylate 315 ...
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TR-443: Oxazepam (CASRN 604-75-1) in Swiss-Webster and B6C3F1Mice... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr443.pdf
... 18 DDD <0.01 18 DDT co.01 18 HCB co.01 18 Mirex co.01 18 Methoxychlor co.05 18 Dieldrin ... o f chemicals such as phenobarbital and mirex (Cattley and Popp, 1989; Schulte-Hermann ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
... Aldrin Heptachlor epoxide DDE DDD DDT HCB Mirex Methoxychlor Dieldrin Endrin Telodrin ... Mirex 314 Methyl Methacrylate 315 Oxytetracycline Hydrochloride 316 1-Chloro-2-methylprope...
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TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox102_508.pdf
... DDD a <0.01 1 DDT a <0.01 1 HCB a <0.01 1 Mirex a <0.01 1 Methoxychlor a <0.05 1 Dieldrin ... Range Number of Samples HCB a <0.01 - 5 Mirex a <0.01 - 5 Methoxychlor a <0.05 - 5 ...
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Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf
... Not Tested Methotrexate* Tested Not Tested Methyl mercury chloride* Tested Not Tested Mirex Not Tested Not Tested Nitrilotriacetate* Tested Not Tested Penicillin G Not Tested Not ...
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TR-600: Di-n-butyl Phthalate Administered in Feed to Sprague... 3.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf
... <0.01 - 2 DDT a <0.01 - 2 HCB a <0.01 - 2 Mirex a <0.01 - 2 Methoxychlor a <0.05 - 2 ... - 25 DDT a <0.01 - 25 HCB a <0.01 - 25 Mirex a <0.01 - 25 Methoxychlor a <0.05 - 25 ...
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TOX-98: Acetoin (CASRN 513-86-0) and 2,3-Pentanedione (CASRN... 3.0MB
https://ntp.niehs.nih.gov/go/tox098
... <0.01 - 8 DDT a <0.01 - 8 HCB a <0.01 - 8 Mirex a <0.01 - 8 Methoxychlor a <0.05 - 8 ... <0.01 - 4 DDT a <0.01 - 4 HCB a <0.01 - 4 Mirex a <0.01 - 4 Methoxychlor a <0.05 - 4 ...
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TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox99_508.pdf
... 5 Heptachlor Epoxide <0.01 - 5 DDE <0.01 - 5 DDD <0.01 - 5 DDT <0.01 - 5 HCB <0.01 - 5 Mirex <0.01 - 5 Methoxychlor <0.05 - 5 Dieldrin <0.01 - 5 Endrin <0.01 - 5 Telodrin <0.01 - 5 ...
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TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf
... <0.01 - 4 DDT a <0.01 - 4 HCB a <0.01 - 4 Mirex a <0.01 - 4 Methoxychlor a <0.05 - 4 ... - 32 DDT a <0.01 - 32 HCB a <0.01 - 32 Mirex a <0.01 - 32 Methoxychlor a <0.05 - 32 ...
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TR-294: Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in... 6.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr294.pdf
... I-BHC (b) Heptachlor (b) Aldrin (b) Heptachlor epoxide (b) DDE (q) DDD (b) DDT (b) HCB (b) Mirex (b) Methoxychlor (q) Dieldrin (b) Endrin (b) Telodrin (b) Chlordane (b) Toxaphene ...
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TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf
... <0.01 ODD 3 <0.01 DDT 3 <0.01 HCB a <0.01 Mirex 3 <0.01 Methoxychlor 3 <0.05 Dieldrin 3 ... (Inhalation) 312 n-Butyl Chloride 313 Mirex 314 Methyl Methacrylate 315 ...
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TOX-89: Toxicity Studies of 5-Amino-o-cresol (CASRN 2835-95-2... 2.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox089_508.pdf
... epoxide <0.01 - 22 DDE <0.01 - 22 DDD <0.01 - 22 DDT <0.01 - 22 HCB <0.01 - 22 Mirex <0.01 - 22 Methoxychlor <0.05 - 22 Dieldrin <0.01 - 22 Endrin <0.01 - 22 ...
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TOX-101: Trimethylsilyldiazomethane (CASRN 18107-18-1) Administered... 6.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox101_508.pdf
... Epoxide a <0.01 - 2 DDE a <0.01 - 2 DDD a <0.01 - 2 DDT a <0.01 - 2 HCB a <0.01 - 2 Mirex a <0.01 - 2 Methoxychlor a <0.05 - 2 Dieldrin a <0.01 - 2 Endrin a <0.01 - 2 ...
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TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox99_508.pdf
... 5 Heptachlor Epoxide <0.01 - 5 DDE <0.01 - 5 DDD <0.01 - 5 DDT <0.01 - 5 HCB <0.01 - 5 Mirex <0.01 - 5 Methoxychlor <0.05 - 5 Dieldrin <0.01 - 5 Endrin <0.01 - 5 Telodrin <0.01 - 5 ...
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Draft TR-600: Di-n-butyl Phthalate (CASRN 84-74-2) Administered... 2.0MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr600_508.pdf
... <0.01 - 2 DDT a <0.01 - 2 HCB a <0.01 - 2 Mirex a <0.01 - 2 Methoxychlor a <0.05 - 2 ... - 25 DDT a <0.01 - 25 HCB a <0.01 - 25 Mirex a <0.01 - 25 Methoxychlor a <0.05 - 25 ...