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TR-567: Ginseng (CASRN 50647-08-0) in F344/N Rats and B6C3F1... 6.7MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr567.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF GINSENG (CAS NO. 50647-08-0) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. ...
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Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf
ephedrine alkaloids from herbal sources (ephedra) are brought to the attention of the CSWG ... The nomination of ephedra- containing supplements to the National Toxicology Program (NTP) ...
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Abstract for TR-567 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr567
Abstract for TR-567 Toxicology and Carcinogenesis Studies of Ginseng in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 50647-08-0 Synonyms/Common Names: Ginseng; ginseng root ...
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Toxicology and Carcinogenesis Studies of Di-n-butyl Phthalate... 1.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/presentations/03dbp_huang_v2_508.pdf
the Toxicology and Carcinogenesis Studies of Di-n-butyl Phthalate (CASRN 84-74-2) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley ® SD ® ) Rats and B6C3F1/N Mice Mimi ...
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Target Organs and Levels of Evidence for TR-567 57KB
https://ntp.niehs.nih.gov/data/tr/500s/tr567levels
Target Organs and Levels of Evidence for TR-567 Toxicology and Carcinogenesis Studies of Ginseng (CAS No. 50647-08-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical ...
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Tox21 Selected Publications 73KB
https://ntp.niehs.nih.gov/whatwestudy/tox21/publications
tox21pubs Tox21 Selected Publications List of Tox21 selected publications Year Publication 2021 Qu W, Crizer DM, DeVito MJ, Waidyanatha S, Xia M, Houck K, Ferguson SS. Exploration ...
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Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf
formulas as an alternative to ephedra have concentrations of the ... on its widespread and increasing use in "ephedra-free" dietary supplements and limited ...
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Minutes: BSC TRRS; Nov. 19, 2009 104KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/november/minutes20091119.pdf
......... 2 Ginseng......was recused from the peer review and vote because of a conflict of interest. Ginseng Dr. ...
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Botanical Dietary Supplements 78KB
https://ntp.niehs.nih.gov/whatwestudy/topics/botanical
root powder Ginkgo biloba extract Ginseng Kava kava extract Milk thistle extract ... Black Cohosh Menstrual and menopausal symptoms TR-603 Ephedra Weight loss, energy, ...
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Peer Review Report: Draft NTP Approach to Genomic Dose-Response... 924KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/ntpexpanel/2017/october/peerreview20171025_508.pdf
National Toxicology Program Peer Review of Draft NTP Approach to Genomic Dose-Response Modeling Expert Panel Meeting October 23-25, 2017 National Institute of Environmental Health ...
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Historical Controls: Pathology Tables by Gavage/Water for B6C3F1... 85KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_gavh2o_path_hist09.pdf
02/10/04 730 50 (1) 32(691) 51.1 Ginseng Battelle Columbus Laboratory 059501106 ... 02/09/04 729 50 (5) 38(711) 63.9 Ginseng Battelle Columbus Laboratory 059501106 ...
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Historical Controls: Pathology Tables by Gavage/Water for Fischer... 85KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_gavh2o_path_hist09.pdf
01/21/04 727 50 (3) 30(679) 498.5 Ginseng Battelle Columbus Laboratory 059501107 ... 01/22/04 728 50 (5) 36(700) 355.0 Ginseng Battelle Columbus Laboratory 059501107 ...
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Historical Controls: Chemicals by Species/Route/Vehicle for Fischer... 206KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009_byroute.pdf
Androstenedione Mice Gavage Water Ginseng Mice Gavage Water Formamide Mice Gavage ... Androstenedione Rats Gavage Water Ginseng Rats Gavage Water Formamide Rats Gavage ...
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Historical Controls: Pathology Tables by Gavage/Water for B6C3F1... 139KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavwatermice2010mar.pdf
02/10/04 730 50(1) 32(691) 51.1 Ginseng Battelle Columbus Laboratory 059501106 ... 02/09/04 729 50(5) 38(711) 63.9 Ginseng Battelle Columbus Laboratory 059501106 ...
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Historical Controls: Pathology Tables by Gavage/Water for Fischer... 139KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavwaterrats2010mar.pdf
01/21/04 727 50(3) 30(679) 498.5 Ginseng Battelle Columbus Laboratory 059501107 ... 01/22/04 728 50(5) 36(700) 355.0 Ginseng Battelle Columbus Laboratory 059501107 ...
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Historical Controls: Pathology Tables by Gavage/Water for B6C3F1... 134KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/micegavwater.pdf
Battelle Columbus Laboratory 052000506 02/10/04 730 50(1) 32(691) 51.1 Ginseng Female Battelle Columbus Laboratory 052000506 02/09/04 729 50(5) 38(711) 63.9 Ginseng NOTE: The text ...
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Historical Controls: Pathology Tables by Gavage/Water for Fischer... 135KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsgavwater.pdf
Battelle Columbus Laboratory 052000505 01/21/04 727 50(3) 30(679) 498.5 Ginseng Battelle ... Battelle Columbus Laboratory 052000505 01/22/04 728 50(5) 36(700) 355.0 Ginseng Battelle ...
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Historical Controls: Pathology Tables by Gavage/Water for B6C3F1... 132KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/micegavwater2013_508.pdf
Battelle Columbus Laboratory 052000506 02/10/04 730 50(1) 32(691) 51.1 Ginseng Battelle ... Battelle Columbus Laboratory 052000506 02/09/04 729 50(5) 38(711) 63.9 Ginseng Battelle ...
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Historical Controls: Pathology Tables by Gavage/Water for Fischer344N... 104KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/ratsf344gavwater2013_508.pdf
Battelle Columbus Laboratory 052000505 01/21/04 727 50(3) 30(679) 498.5 Ginseng Female Battelle Columbus Laboratory 052000505 01/22/04 728 50(5) 36(700) 355.0 Ginseng NOTE: The ...
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Comparing and Interpreting Tox21 Data Analysis Approaches 18KB
https://ntp.niehs.nih.gov/iccvam/meetings/11wc/karmaus-tox21-wc11_508.pdf
Comparing and Interpreting Tox21 Data Analysis Approaches March 2021 NICEATM Abstract: 11 th World Congress Comparing and Interpreting Tox21 Data Analysis Approaches A.L. Karmaus 1 ...
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Presentation: NRC Report: Application of Modern Toxicology Approaches... 286KB
https://ntp.niehs.nih.gov/iccvam/meetings/at-wksp-2015/session2/4-dorman-508.pdf
NRC Report: Application of Modern Toxicology Approaches for Predicting Acute Toxicity for Chemical Defense David C. Dorman, DVM, PhD North Carolina State University Predictive ...
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Agenda: BSC TRRS; Nov. 19, 2009 31KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/november/agenda111909.pdf
Inhalation, male and female F344/N rats and B6C3F1 mice Ginseng [50647-08-0] TR 567 Ginseng is a perennial, aromatic herb widely used in herbal remedies for enhancing stamina and ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 15KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont_2013_by_list_of_studies_508.pdf
Mice B6C3F1 Male and Female Gavage Water Ginseng Mice B6C3F1 Male and Female Gavage Water ... F 344/N Male and Female Gavage Water Ginseng Rats F 344/N Male and Female Inhalation ...
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Applying In vitro Approaches to Understand Complex Mixtures in... 5.3MB
https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-rider-508.pdf
... Completed . Aloe vera nondecolorized whole leaf extract . Bitter orange extract . Ephedra (ma huang) . Ginseng root extract . Ginkgo biloba extract . Goldenseal root powder . Green ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 14KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/histcont_2010_studies.pdf
Mice B6C3F1 Male and Female Gavage Water Ginseng Mice B6C3F1 Male and Female Gavage Water ... F 344/N Male and Female Gavage Water Ginseng Rats F 344/N Male and Female Gavage Water ...
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Presentation: From QSAR to Big Data: Developing Mechanism-Driven... 2.0MB
https://ntp.niehs.nih.gov/iccvam/meetings/at-wksp-2015/session2/2-zhu-508.pdf
From QSAR to Big Data: Developing Mechanism-Driven Predictive Models for Animal Toxicity Hao Zhu Department of Chemistry The Rutgers Center for Computational and Integrative ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf
Mice B6C3F1 Male and Female Gavage Water Ginseng Mice B6C3F1 Male and Female Inhalation ... F 344/N Male and Female Gavage Water Ginseng Rats F 344/N Male and Female Gavage Water ...
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Literature Search Results: Systematic Review of Fluoride Exposure... 768KB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf
... phosphorylation and TCA enzymes in discrete brain regions of mice exposed to high fluoride: Amelioration by panax ginseng (ginseng) and lagerstroemia speciosa (banaba) extracts. ...
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NICEATM and ICCVAM Publications, 2020-2021 124KB
https://ntp.niehs.nih.gov/iccvamreport/2021/reference/publications
NICEATM and ICCVAM Publications, 2020-2021 NICEATM and ICCVAM Reports ICCVAM. 2020. Biennial Progress Report 2018-2019 [Internet]. Research Triangle Park (NC): National Institute ...
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P08: Statisitical Analysis of Primary Tumors for Mice (20209... 159KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20209_tables/04_f1_m3_p08.pdf
(INHALATION AIR) 99031-04 -- Ginkgo biloba extract (GAVAGE CORN OIL) 20005-06 -- Ginseng (GAVAGE WATER) 20203-04 -- Green tea extract (GAVAGE WATER) 20006-04 -- ...
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TR-600: Di-n-butyl Phthalate Administered in Feed to Sprague... 3.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf
di-N-buTyl PhThalaTe (casRN 84-74-2) admiNisTeRed iN feed To sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs aNd b6c3f1/N mice NTP TR 600 NOVEMBER 2021 NTP Technical Report on ...
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SOT Annual Meeting: NIEHS and NTP Activitie; March 7-11, 2010 281KB
https://ntp.niehs.nih.gov/ntp/pressctr/mtgs_wkshps/sot_49_activities.pdf
U.S. Department of Health & Human Services National Institutes of Health 1 Society of Toxicology Annual Meeting . March 7-11, 2010 NIEHS and NTP Activities (Booth 1600) Sunday, ...
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Agenda: NTP Workshop: Role of Environmental Chemicals in the... 149KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/diabetesobesity/finalagenda1_19_2011klh.pdf
NTP Workshop: Role of Environmental Chemicals in the Development of Diabetes and Obesity January 11-13, 2011 Marriott Crabtree Valley, 4500 Marriott Drive, Raleigh, North Carolina ...
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NIEHS Update: ICCVAM Public Forum 2015 1.9MB
https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2015/niehs-iccvampubforum-2015-508.pdf
NIEHS Update Nigel Walker, PhD, DABT Deputy Director for Research Division of the National Toxicology Program National Institute of Environmental Health Sciences ...
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COVID-19 Therapeutic Development 4.7MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2020/september/present/2b-2-sidhu-508.pdf
COVID-19 Therapeutic Development With Synthetic Antibody Technology Sachdev Sidhu Toronto Recombinant Antibody Centre The Donnelly Centre University of Toronto 1 lmn1unization ...
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Minutes: BSC; Nov. 30-Dec. 1, 2010 984KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2010/novdec/minutes20101201.pdf
National Toxicology Program Board of Scientific Counselors November 30 - December 1, 2010 National Institute of Environmental Health Sciences Research Triangle Park, NC Table of ...
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Presentation: Report on Workshop: Addressing Challenges in the... 2.3MB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2016/june/presentations/botanicals_508.pdf
No Ginkgo biloba Some Some Clear Clear Ginseng No No No No Goldenseal Clear Clear Some ... Increased heart rate and blood pressure Ephedra Cardiotoxicity Completed History of NTP ...
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New Approach Methodologies for Exposure from EPA's ExpoCast Project... 2.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2019/september/presentations/2-3-isaacs.pdf
New Approach Methodologies for Exposure from EPA's ExpoCast Project Kristin Isaacs National Exposure Research Laboratory Office of Research and Development, United States ...
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NICEATM Update: ICCVAM Public Forum 2015 1.8MB
https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2015/niceatm-iccvampubforum-2015-508.pdf
ICCVAM Public Forum NICEATM Update Warren Casey, PhD, DABT Director, NICEATM Division of the National Toxicology Program, NIEHS May 27, 2015 NICEATM NTP Interagency Center for the ...
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Notices 199KB
https://ntp.niehs.nih.gov/sites/default/files/2023-08/2023-16427.pdf
0884 Federal Register / Vol. 88, No. 147 / Wednesday, August 2, 2023 / Notices Dated: July 27, 2023. Tyeshia M. Roberson-Curtis, Program Analyst, Office of Federal Advisory ...
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Agenda: BSC; Nov. 30-Dec. 1, 2010 85KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2010/novdec/agenda20101130.pdf
NTP Board of Scientific Counselors (BSC) Meeting Preliminary Agenda* Rodbell Auditorium, Rall Building National Institute of Environmental Health Sciences (NIEHS) Research ...
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Agenda: TRPRP; April 2, 2021 156KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2021/april/agendatrprp20210402_508.pdf
Revised March 19, 2021 1 Friday, April 2 10:00 a.m. - approximately 5:00 p.m. EDT (meeting may end sooner or go longer) Breaks and lunch will be taken at the discretion of the ...
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Historical Controls: All Route and Vehicles for Rats; Studies... 162KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2008/r_hcrtp_allrte_20081100.pdf
... 01/21/04 727 50 (3) 30(679) 498.5 Ginseng Southern Research Institute 059900705 04/... 01/22/04 728 50 (5) 36(700) 355.0 Ginseng Southern Research Institute 059900705 04/...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 176KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-miceallroutes.pdf
... 02/10/04 730 50 (1) 32(691) 51.1 Ginseng Southern Research Institute 059900706 05/... 02/09/04 729 50 (5) 38(711) 63.9 Ginseng Southern Research Institute 059900706 05/...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 174KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-ratsallroutes.pdf
... 01/21/04 727 50 (3) 30(679) 498.5 Ginseng Southern Research Institute 059900705 04/... 01/22/04 728 50 (5) 36(700) 355.0 Ginseng Southern Research Institute 059900705 04/...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf
... 02/10/04 730 50(1) 32(691) 51.1 Ginseng Southern Research Institute 059900706 05/... 02/09/04 729 50(5) 38(711) 63.9 Ginseng Southern Research Institute 059900706 05/...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 276KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_allroutes_508.pdf
02/10/04 730 50(1) 32(691) 51.1 Ginseng Battelle Columbus Laboratory 052020304 ... 02/09/04 729 50(5) 38(711) 63.9 Ginseng Battelle Columbus Laboratory 052020304 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 189KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_allroutes_508.pdf
01/21/04 727 50(3) 30(679) 498.5 Ginseng Battelle Columbus Laboratory 052000705 ... 01/22/04 728 50(5) 36(700) 355.0 Ginseng Battelle Columbus Laboratory 052000705 ...
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TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox102_508.pdf
oN T T he oxiciTy STudieS of TRaNS-ReSveRaTRol (caSRN 501-36-0) admiNiSTeRed by GavaGe foR Two weekS oR ThRee moNThS To f344/NTac RaTS, wiSTaR haN [cRl:wi(haN)] RaTS, aNd b6c3f1/N ...
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National Institute of Environmental Health Sciences: Jennifer... 156KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/jennifer
Skip Navigation Jennifer M. Fostel, Ph.D. National Institute of Environmental Health Sciences (NIEHS) Office of Program Operations Much of the work carried out by DTT is in support ...
