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97 results found for "300-62-9".

  1. TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf

    TOXICOLOGY AND CARCINOGENESIS STUDIES OF dl-AMPHETAMINE SULFATE (CAS NO. 60-13-9) IN F344/... STUDIES OF d2-AMPHETAMINE SULFATE (CAS NO. 60-13-9) IN F344/N RATS AND B6C3F1 MICE (FEED ...

  2. CERHR Monograph: Amphetamines 4.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf

    ... Amphetamines evaluated were d-and d,l-amphetamine and methamphetamine. Amphetamine is approved by the U.S. Food and Drug Administration for the treatment of atten- tion deficit ...

  3. Abstract for TR-387 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr387

    ...l-Amphetamine Sulfate in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 60-13-9 Chemical Formula: C18H28N2 O4S Molecular Weight: 368.5 Synonyms/Common Names: (±)-Amphetamine ...

  4. Target Organs and Levels of Evidence for TR-387 56KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr387levels

    Toxicology and Carcinogenesis Studies of dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N .../Exposure Levels Study Laboratory DL-amphetamine sulfate 60-13-9 04/25/1990 Dosed-Feed ...

  5. Minutes: BSC TRRS; Nov. 20, 1989 820KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1989/nov/89nov20trrsmins_508.pdf

    Route Page Number Long Term Studies dl-Amphetamine S u l f a t e 60- 13-9 Feed 1 Ethylene ... MINUTES PEER REVIEW PANEL MEETING November 20-21 , 1989 dl-Amphetamine S u l f a t e . Dr. ...

  6. Minutes: BSC TRRS; April 25, 1990 596KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1990/apr/trrs25apr1990mins_508.pdf

    Deferred Studies Reevaluation DL-Amphetamine S u l f a t e Ethylene Thiourea CAS No. ... accepted unanimously w i t h eleven votes. dl-Amphetamine S u l f a t e -- Reevaluation. ...

  7. TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf

    ... hydrochloride a is piperidine derivative structurally related to amphetamine. ... The usefulness of stimulant therapy (amphetamine) in the treatment o f children's behavior ...

  8. CERHR Monograph: Methylphenidate 11.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/stimulants/methylphenidate/methylphenidatemonograph.pdf

    ...overdose.are.similar.to.those.of.other.amphetamine-like.drugs..Signs. ...ymptoms.similar.to.those.observed.with.amphetamine. toxicity,.including.psychotic.episodes...

  9. Presentation: The EURL ECVAM Toxicokinetics Report and EURL ECVAM... 2.5MB

    https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/wksp-ppts/0-2-paini-508.pdf

    ... 107028 acrylamide 79061 4 amiodarone 1951253 2 1 amitriptyline 50486 1 2 amphetamine 300629 1 1 1 antipyrine 60800 1 arsenic trioxide 1327533 1 1 Double click a cell (if it ...

  10. CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf

    ... (ADHD). (147),. and. decreased. amphetamine-induced.activity.in.bisphenol.A- ... Laviola.G,.Gioiosa.L,.Adriani.W,.Palanza. P.(2005) Brain Res Bull..D-Amphetamine- related. ...

  11. Minutes: BSC; March 14, 1983 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1983/march/bsc_mins19830314_508.pdf

    ... i t i v i t y of the t e s t s with D-amphetamine s u l f a t e and methylmercuric ... She presented data which (1) compared controls from the amphetamine study with controls ...

  12. Minutes: BSC; Aug. 18, 2005 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2005/august/bscmins2005aug18_508.pdf

    ... The expert panel reports for amphetamine and methylphenidate and the NTP-CERHR monographs for fluoxetine and acrylamide are on the CERHR website. CERHR sponsored a symposium, "Gene ...

  13. Minutes: BSC; March 13, 1990 1.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1990/march/19900313-14bsc_minutes_508be.pdf

    ... of Experts would meet on April 25 to peer review NTP draft TechnTCar-Reports on Dl-amphetamine sulfate, 3,3'-dimethylbenzidine dihydrochlor1de, ethylene thiourea, sodium azide, ...

  14. Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf

    ... As an alternative for the structurally related illegal drug, Ecstasy (4-methyl-2-dimethoxy- amphetamine, MDMA), ephedra supplements are sometimes sold outside usual channels of ...

  15. Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf

    ... > tyramine > p-hydroxyephedrine, L- amphetamine > L-ephedrine > phenethylamine > ... H H H H H Pharmacologically related to amphetamine. α2 (Matsuoka et al., 1993); β1, pos. ...

  16. TOX-95: Toxicity Studies of Myristicin (CASRN 607-91-0) Administered... 3.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox095_508.pdf

    ... 35 No other studies have identified amphetamine derivatives of myristicin, or any other ... on locomotor activity similar to amphetamine; whereas intraperitoneal administration ...

  17. TR-455: Codeine (CASRN 76-57-3) in F344 Rats and B6C3F1Mice ... 15.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr455.pdf

    ... neuroendocrine effects (such as dl-amphetamine sulfate and methyl- ... Toxicology (NTP) Toxicology and Studies Carcinogenesis of dl-Amphetamine Sulfate (CAS No. ...

  18. TR-430: C.I. Direct Blue 218 (CASRN 28407-37-6) in F344/N Rats... 16.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr430.pdf

    ... Inc C.I. Direct Blue 218 dl-Amphetamine Sulfate Overall Historical Incidence ... Associates, Inc C.I. Direct Blue 218 &-Amphetamine Sulfate Overall Historical Incidence ...

  19. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence P Clear Evidence P Clear Evidence P Clear Evidence TR-387 04/25/90 dl-Amphetamine Sulfate 60-13-9 NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-386 ...

  20. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Technical Report TR-387 PDF (10.43 MB) Toxicology and Carcinogenesis Studies of dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1991 Technical ...

  21. CERHR Monograph: Potential Human Reproduction Effects of Styrene 6.0MB

    https://ntp.niehs.nih.gov/ntp/ohat/styrene/styrene_monograph.pdf

    ... Six. pups. of. "either. sex". from. each. group. were. used..Amphetamine- ...od.was.associated.with.an.increase. in.amphetamine-stimulated.locomotor.activity.and.an.in...

  22. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Carcinogenicity TR-387 PDF (10.43 MB) Toxicology and Carcinogenesis Studies of dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1991 Long-Term ...

  23. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Technical Report TR-387 PDF (10.43 MB) Toxicology and Carcinogenesis Studies of dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1991 Technical ...

  24. Minutes: BSC; March 27, 1984 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf

    ... Acid, Reserpine, Propranolol Agent GB, Agent GD, Ultrasound, Silicone, d-Amphetamine . ... Data from the behavioral teratoiogy pilot studies employing amphetamine and mefhylmercury ...

  25. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... 319.0 2.1 978.3 6.44 151.91 2.1 262 47 Amphetamine sulfate 60-13-9 726.02 1.97 55.3 0.15 ... 50.6 0.19 NA NA 266.32 0.19 262 47 Amphetamine sulfate 60-13-9 726.02 1.97 55.3 0.15 ...

  26. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... I fluoride 1.85 4.29 180.1 262 47 Amphetamine sulfate 1.97 0.15 55.3 107 2 ... 0.036 0.19 50.6 262 47 Amphetamine sulfate 1.97 0.15 55.3 8 Digitoxin ...

  27. TR-539: Multigenerational Reproductive Toxicology Study of Genistein... 24.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr539.pdf

    ... Genistein significantly potentiated the amphetamine-stimulated release of dopamine in the ... Effects of lifelong dietary exposure to genistein or nonylphenol on amphetamine-stimulated ...

  28. TR-406: g-Butyrolactone (CASRN 96-48-0) in F344/N Rats and B6C3F1Mice... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr406.pdf

    ... but notthat o f pentobarbital, and e) amphetamine, a drug causing the release o f central ... Diphenhydramine Hydrochloride 387 386 Amphetamine Sulfate Tetranitromethane 358 357 ...

  29. TR-380: l-Epinephrine Hydrochloride (CASRN 55-31-2) in F344/N... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr380.pdf

    ... injections of adrenalin chloride and d-amphetamine sulfate on subsequent emotionality and ... and Carcinogenesis Studies of dl- Amphetamine Sulfate in F344/N Rats and B6C3Ft Mice. ...

  30. TR-445: Scopolamine Hydrobromide Trihydrate (CASRN 6533-68-2... 13.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr445.pdf

    ... Res. 257,229-306. Bauer, R.H. (1984). Differentialof effects d-amphetamine and scopolamine ... The topography of amphetamine and scopolamine-induced hyperactivity: Toward an activity ...

  31. TR-378: Benzaldehyde (CASRN 100-52-7) in F344/N Rats and B6C3F1Mice... 14.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr378.pdf

    ... Copenhagen, p. 96. 39. Honecker, H. (1975) CNS (central nervous system)--Availability of amphetamine from am- phetaminil. Int. J. Clin. Pharmacol. Biopharm. 12:121. Cited in ...

  32. TOX-69: Butanal Oxime (CASRN 110-69-0) 3.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox069.pdf

    ... Toxicol. 40, 205-210. Hucker, H.B. (1973). Phenylacetone oxime - An intermediate in amphetamine deamination. Drug Metab. Dispos. 1, 332-336. Integrated Laboratory Systems (ILS) ...

  33. TR-447: Acetonitrile (CASRN 75-05-8) in F344/N Rats and B6C3F1Mice... 14.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr447.pdf

    ... NC. National Toxicology (NTP) Program Toxicology and Studies Carcinogenesis dl-Amphetamine Sulfate (CAS No. (1991). ' of ' 60-13-9) in F344/N Rats and B6C3Fl Mice (Feed ...

  34. TR-503: Chloral Hydrate (Ad Libitum and Dietary Controlled) ... 5.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr503.pdf

    ...o-2,4-dibromoanthraquinone Feed 387 dl-Amphetamine Sulfate Feed 391 Tris(2-Chloroethyl) ... Toxicology and Carcinogenesis Studies of dl-Amphetamine Sulfate (CAS No. 60-13-9) in F344/...

  35. TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf

    ... Rmrsone 335 Methyl Bromide 346 Chlomthane 386 Tetranitromethane 347 D-Limonene 387 Amphetamine Sulfate 348 a-Methyldopa Sesquihydrate 3 % Ethylene Thiourea 349 Pentachlorophenol ...

  36. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    ... Benzaldehyde 2-Chloroacetophenone Epinephrine Hydrochloride d-Carvone Furfural 1,2,3-Trichloropropane Methyl Bromide Tetranitromethane Amphetamine Sulfate TR No. 388 389 390 391 ...

  37. MFDS NAMs Report: Regulatory Acceptance and Research Outcomes 20.5MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-01/MFDS_NAMs_Report-2023-508.pdf

    ... accomplishment Number of papered published in SCI-grade journal 9 4-EA-NBOMe, an amphetamine derivative, alters glutamatergic synaptic transmission through 5-HT receptors on ...

  38. TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf

    ... p-Chlomamiline Hydrochloride 389 388 387 386 385 382 W,ium Azide Ethylene Thiourea Amphetamine Sulfate Tetranitromethane Methyl Bromide FUrfUral 361 360 359 358 357 ...

  39. TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf

    ... 380 Epinephrine Hydrochloride 381 d-Carvone 382 Furfural 386 Tetranitromethane 387 Amphetamine Sulfate 390 3,3 -Dimethylbenzidine Dihydrochloride 391 Tris(2-chloroethyl) Phosphate ...

  40. TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf

    ... 380 Epinephrine Hydrochloride 3 8 1 d-Cawone 382 Furfural 386 Tetranitromethane 387 Amphetamine Sulfate 390 3,3 -Dimethylbenzidine Dihydrochloride 391 Tris(Zchlomthy1) Phosphate ...

  41. TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf

    ... Bromide 347 D-Limonene 386 Tetranitromethane 348 @-Methyldopa Sesquihydrate 387 Amphetamine Sulfate 349 Pentachlorophenol 388 Ethylene Thiourea 350 Tribromomethane 389 Sodium ...

  42. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... (outlier), NTP 00 mg/kg Disinfectant Amphetamine sulfate 55 MEIC, EDIT, RC (outlier), ... II 368.37 42.3 15582.1 17.4 6409.6 Amphetamine sulfate 368.54 1.97 726.0 0.15 55.3 ...

  43. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... 2-Amino-4-Nitrophenol 2-Amino-5-Nitrophenol 11-Aminoundecanoic Acid dl-Amphetamine Sulfate Ampicillin Trihydrate Asbestos, Amosite (Hamsters) Asbestos, Amosite (Rats) ...

  44. TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB

    https://ntp.niehs.nih.gov/go/tr385

    ... N,N-Dimethylaniline Hexachloroethane 386 387 389 390 391 393 395 Tetranitromethane Amphetamine Sulfate Sodium Azide 3,3-Dimethylbenzidine Dihydrochloride Tris(2-chloroethyl) ...

  45. TR-396: Monochloroacetic Acid (CASRN 79-11-8) in F344/N Rats... 14.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr396.pdf

    ... 358 357 8-Methoaypsoralen Octuatoxin A Hydrahlomthiazide 389 387 386 sodium Azide Amphetamine Sulfate Tetranitromethane 360 N,N-Dimethylaniline 390 3,3'-Dmthylbemidhe ...

  46. TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf

    ... Methyl Bromide 340 Iodinated Glycerol 386 Tetranitromethane 341 Nitrofurantoin 387 Amphetamine Sulfate 342 Dichlorvos 388 Ethylene Thiourea 343 Benzyl Alcohol 389 Sodium Azide 344 ...

  47. TR-401: 2,4-Diaminophenol Dihydrochloride (CASRN 137-09-7) in... 12.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr401.pdf

    ... Hydrochloride 389 388 387 386 385 382 Sodium Azide Ethylene Thiourea Amphetamine Sulfate Tetranitromethane Methyl Bromide Furfural 3 6 1 360 359 358 357 ...

  48. TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr412.pdf

    ... E t k o - C h h d m m W o n o n i t n i b & & * z - a m ~ @ m m e Epinephine H y d t u c h h S e d 4 3 W O M Flu-ruml Methyl BPomide Tetranitromethane Amphetamine Sulfate Ethylene ...

  49. TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr415.pdf

    ... 354 Epinephrine Hydmhloride 355 d-Qrvone 356 Furfural 357 Teteanitmmethane 358 Amphetamine Sulfate 359 Sasiium Azide 360 3,3'-Dimethylbenzidine Dihydmhloside 3 5 1 ...

  50. TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf

    ... 2-Amino-4-Nitrophenol 2-Amino-5-Nitrophenol 11-Aminoundecanoic Acid dl-Amphetamine Sulfate Ampicillin Trihydrate Anthraquinone Asbestos, Amosite (Hamsters) Asbestos, ...

 
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