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RoC Profile: Chlorambucil; 15th RoC 2021 123KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chlorambucil.pdf
Chlorambucil CAS No. 305-03-3 Known to be a human carcinogen First listed in the Second Annual Report on Carcinogens (1981) Also known as 4-[p-[bis(2-chloroethyl)amino]phenyl]butyr...
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Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf
Carboplatin NA NA D Carmustine 2A NA D Chlorambucil 1 Known D Cisplatin 2A Reasonably ... OR carmustine OR Cerubidine OR chlorambucil OR cisplatin OR cis- platinum OR ...
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Listed Substances; 15th RoC 2021 76KB
https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf
Ether 1,3-Butadiene 1,4-Butanediol Dimethanesulfonate Cadmium and Cadmium Compounds Chlorambucil 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (see Nitrosourea ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
...)amino]phenyl]butyric acid see Chlorambucil bis(2-chloroethyl)sulfide see Mustard Gas 4-[bis(2-chlomethyl)amino]benzenebutanoic acid see Chlorambucil 4,4'-bis(dimethylamino)benzoph...
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Appendix G; 15th RoC 2021 73KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf
... (hydrazine) see Hydrazine and Hydrazine Sulfate 303-47-9 see Ochratoxin A 305-03-3 see Chlorambucil 313-67-7 (aristolochic acid I) see Aristolochic Acids 319-84-6 ...
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Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf
... Centrophenoxine was reported to potentiate the antitumor activity of chlorambucil in vivo. ... reported that centrophenoxine potentiated the antitumor activity of chlorambucil in vivo. ...
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RoC Background Document: Thiotepa; Nov. 18-19, 1996 2.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/thiotepa1_508.pdf
... Thiotepa used in combination with irradiation and chlorambucil or cyclophosamide in two ... Melphalan, chlorambucil, cyclophosphamide, and treosulphan (alkylating agents known to be ...
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NTP Monograph: Developmental Effects and Pregnancy Outcomes Associated... 23.8MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/chemopregnancy_monofinal_508.pdf
... 8 Carmustine 3 Appendix D Table 4 Chlorambucil 10 Appendix D Table 5 Cisplatin 105 ... Bleomycin 13 49 Appendix C Table 6 Chlorambucil 3 4 Appendix D Table 38 Cisplatin 1 1 ...
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Appendices A-G; 15th RoC 2021 448KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf
...oroethyl)amino]phenyl]butyric acid see Chlorambucil bis(2-chloroethyl)sulfide see Mustard ... Sulfate 303-47-9 see Ochratoxin A 305-03-3 see Chlorambucil 313-67-7 (aristolochic ...
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OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1018KB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201510_508.pdf
... OR Cerubidine[tiab] OR chlorambucil[tiab] OR cisplatin[tiab] OR ... OR carmustine OR cerubidine OR chlorambucil OR cisplatin OR cis-platinum OR ...
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OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1.1MB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201812_508.pdf
... OR Cerubidine[tiab] OR chlorambucil[tiab] OR cisplatin[tiab] OR cis- ... OR carmustine OR cerubidine OR chlorambucil OR cisplatin OR cis-platinum OR ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... 45 Quinine * HCl 0.075 1.72 620.8 190 Chlorambucil 0.076 0.25 76.1 191 Dimenhydrinate ... monochloroacetate 1.45 0.65 75.7 190 Chlorambucil 0.076 0.25 76.1 149 Chromium VI ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... 45 Quinine * HCl 130-89-2 27.07 0.075 620.8 1.72 1158.6 3.21 360.92 1.72 190 Chlorambucil 305-03-3 23.12 0.076 76.1 0.25 100.4 0.33 304.24 0.25 191 Dimenhydrinate 523-87-5 35.72 ...
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NTP Monograph: Systematic Review of Occupational Exposure to... 6.2MB
https://ntp.niehs.nih.gov/ntp/ohat/oeccaaho/mgraph/occchemo_final20190300_508.pdf
... OR Cerubidine[tiab] OR chlorambucil[tiab] OR cisplatin[tiab] OR ... OR carmustine OR cerubidine OR chlorambucil OR cisplatin OR cis-platinum OR ...
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Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf
... Not Tested Caffeine* Tested Tested Carbon tetrachloride* Not Tested Not Tested Chlorambucil** Not Tested Not Tested Coumarin* Tested Not Tested Cyclophosphamide** Tested ...
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ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... acid 300.48 0.11 33.1 6.66 2001.2 Captan 300.59 0.0039 1.2 33.3 10009.6 Chlorambucil 304.24 0.076 23.1 0.25 76.1 Orphenadrine * HCl 305.88 0.49 149.9 1.39 425.2 ...
