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6 results found for "42399-41-7".

  1. Presentation: Predictive Power of PBPK Modeling and In Silico... 5.0MB

    https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/wksp-ppts/3-1-fraczkiewicz-508.pdf

    ... CYP Substrate? 1A2 2C19 2C9 2D6 3A4 CYP Subst Star Plot: Predicted to be a substr. for all 5 CYPs except 1A2 Diltiazem CYP Metabolism Models 23 Sites of Metabolism CYP Substrate? ...

  2. TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox99_508.pdf

    ... prescribed medications propranolol and diltiazem in healthy male volunteers. 43 This ... and the antihypertensive drug diltiazem show decreased bioavailability when ...

  3. TOX-99: A Gum Guggul Extract Formulation Administered by Gavage... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox99_508.pdf

    ... prescribed medications propranolol and diltiazem in healthy male volunteers. 43 This ... and the antihypertensive drug diltiazem show decreased bioavailability when ...

  4. TR-473: Theophylline (CASRN 58-55-9) in F344/N Rats and B6C3F1Mice... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr473.pdf

    ... serotonin-reuptake inhibitor); the calcium antagonists nifedipine, verapamil, and diltiazem; the H -receptor antagonists cimetidine and famotidine; the 2 oral contraceptive ...

  5. Response to Request for Data and Information on Zebrafish Embryo... 1.6MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-26605/kanungo-508.pdf

    ... Fetal Neonatal Ed. 85: F53-F56. Saha N, Chugh Y, Sankaranarayanan A, Datta H. 1990. Interactions of verap- amil and diltiazem with ketamine: effects on memory and sleeping time in ...

  6. TOX-26: Ethylene Glycol Ethers 2-Methoxyethanol, 2-Ethoxyethanol... 8.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox026.pdf

    ... In these studies, one, two, three, or four doses of the calcium channel blockers verapamil or diltiazem, given in combination with a single gavage dose of 300 mg/kg ...

 
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