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42 results found for "434-07-1".
  1. TR-485: Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology... 12.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr485.pdf

    OF OXYMETHOLONE (CAS NO. 434-07-1) IN F344/N RATS AND TOXICOLOGY STUDIES OF OXYMETHOLONE IN B6C3F MICE 1 (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research ...

  2. RoC Profile: Oxymetholone; 15th RoC 2021 136KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/oxymetholone.pdf

    Oxymetholone CAS No. 434-07-1 Reasonably anticipated to be a human carcinogen First listed in the First Annual Report on Carcinogens (1980) O CH 3 OH CH 3 H C HO CH 3 ...

  3. Abstract for TR-485 79KB

    https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr485

    Abstract for TR-485 Toxicology and Carcinogenesis Studies of Oxymetholone in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F1 Mice (Gavage Studies) CASRN: 434-07-1 ...

  4. Minutes: BSC TRRS; Oct. 30, 1998 882KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1998/oct/trrs30oct1998mins_508.pdf

    Methyleugenol 93-15-2 Gavage (Ethylene Glycol Monobutyl Ether) 6 2-Butoxyethanol 111-76-2 InhalatIOn 8 Glutaraldehyde 111-30-8 Inhalation 11 Oxymetholone 434-07-1 Gavage 12 .,.. ...

  5. Target Organs and Levels of Evidence for TR-485 59KB

    https://ntp.niehs.nih.gov/data/tr/400s/tr485levels

    Target Organs and Levels of Evidence for TR-485 Toxicology and Carcinogenesis Studies of Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in ...

  6. Uterus - Hyperplasia, Stromal - Nonneoplastic Lesion Atlas 287KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/HyperplasiaStromal

    National Toxicology Program. 1999. NTP TR-485. Toxicology and Carcinogenesis Studies of Oxymetholone (CAS No. 434-07-01) in F344/N Rats and Toxicology Studies of Oxymetholone in ...

  7. Uterus - Hyperpalsia, Stromal 264KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/uterus/hypstr/uterus-hyperplasia-stromal-pdf-508.pdf

    1999. NTP TR-485. Toxicology and Carcinogenesis Studies of Oxymetholone (CAS No. 434-07-01) in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F1 Mice (Gavage Studies). ...

  8. Studies on Historical Control Reports for NIH-07 Feed 312KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/nih-07_1999/histcont_1999_by_list_of_studies_508.pdf

    Gavage Methylcellulose Methyleugenol Rats Fischer344 Gavage Methylcellulose Oxymetholone Rats Fischer344 Gavage Water Scopolamine hydrobromide trihydrate Rats Fischer344 ...

  9. Clitoral Gland, Duct - Dilation - Nonneoplastic Lesion Atlas 300KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/clitoral-gland/Duct-Dilation

    National Toxicology Program. 1999. NTP TR-485. Toxicology and Carcinogenesis Studies of Oxymetholone (CAS No. 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in ...

  10. Clitoral gland - Hyperplasia - Nonneoplastic Lesion Atlas 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/clitoral-gland/Hyperplasia

    Stoll RE, Holden HE, Barthel CH, Blanchard KT. 1999. Oxymetholone: III. Evaluation in the ... Stoll RE, Holden HE, Blanchard KT. 1999. Oxymetholone: II. Evaluation in the Tg-AC ...

  11. Nose, Olfactory Epithelium, Glands - Hyperplasia 301KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/clitoral_gland/hyperpl/clitoral-gland-hyperplasia-pdf-508.pdf

    HE, Barthel CH, Blanchard KT. 1999. Oxymetholone: III. Evaluation in the p53+/- ... RE, Holden HE, Blanchard KT. 1999. Oxymetholone: II. Evaluation in the Tg-AC ...

  12. TR-560: Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1... 7.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr560.pdf

    ... Oxymetholone, an androgenic anabolic steroid, was carcinogenic in female rats based upon ... The use of oxymetholone to treat anemia has been associated with liver tumors in patients, ...

  13. Clitoral Gland, Duct - Dilation 608KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/clitoral_gland/ddilat/clitoral-gland-duct-dilation-pdf-508.pdf

    ... 1999. NTP TR-485. Toxicology and Carcinogenesis Studies of Oxymetholone (CAS No. 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F 1 Mice (Gavage Studies). ...

  14. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... Its Hydrochloride 373-02-4 (nickel acetate) see Nickel and Nickel Compounds 434-07-1 see Oxymetholone 443-48-1 see Metronidazole 446-86-6 see Azathioprine 475-80-9 (aristolochic ...

  15. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... 15 Listings) o-Nitrotoluene Norethisterone Ochratoxin A 4,4'-Oxydianiline Oxymetholone Pentachlorophenol and By-products of Its Synthesis Phenacetin (see Phenacetin and ...

  16. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Tested in Species/Sex NT Chemical Not Tested in Species/Sex TR-485 10/30/98 Oxymetholone 434-07-1 EE Equivocal Evidence P Clear Evidence NT Chemical Not Tested in Species/Sex NT ...

  17. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-485 PDF (12.47 MB) Toxicology and Carcinogenesis Studies of Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F1 Mice ...

  18. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... Adriamycin 17-hydroxy-2-(hydroxymethylene)-17-methyl-5α,17β-androstan-3- one see Oxymetholone (17α)-17-hydroxy-19-norpregn-4-en-20-yn-3-one see Norethisterone National ...

  19. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-485 PDF (12.47 MB) Toxicology and Carcinogenesis Studies of Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F1 Mice ...

  20. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-485 PDF (12.47 MB) Toxicology and Carcinogenesis Studies of Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F1 Mice ...

  21. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ...7-methyl-5α,17β-androstan-3- one see Oxymetholone (17α)-17-hydroxy-19-norpregn-4-en-20-... acetate) see Nickel and Nickel Compounds 434-07-1 see Oxymetholone 443-48-1 see ...

  22. Minutes: BSC; May 20, 1999 365KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1999/may/19990520bscmins_508.pdf

    ... Gavage studies with oxymetholone gave equivocal evidence in male rats and clear evidence in female rats (liver, lung, skin). Dermal studies with triethanolamine had been peer ...

  23. Minutes: BSC; July 14, 1987 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1987/december/19871214bsc_minutes_508be.pdf

    ... Glycol (25263-71-8); (5) Methylene Diphenyl Diisocyanate: and (6) Oxymetholone. ... same as f o r workers 6. Oxyrnethol one (434-07-1) 1. NIEHS 2. N C I -Subchronic studies - ...

  24. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... The chemicals are ethylene glycol monobutyl ether, glutaraldehyde, methyleugenol, and oxymetholone. C. Interagency Coordinating Committee on the Validation of Alternative Methods ...

  25. TR-496: Fumonisin B1(CASRN 116355-83-0) in F344/N Rats and B6C3F1Mice... 33.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr496.pdf

    ... Toxicology and Carcinogenesis Studies of Oxymeth- olone (CAS No. 434-07-1) in F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F 1 Mice (Gavage Studies). Technical Report ...

  26. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  27. TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  28. TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  29. TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr498.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  30. TR-511: Dipropylene Glycol (CASRN 25265-71-8) in F344/N Rats... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr511.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  31. TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1Mice... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr508.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  32. TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 10.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr509.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  33. TR-512: Elmiron (CASRN 37319-17-8) in F344/N Rats and B6C3F1Mice... 12.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr512.pdf

    ... Ochratoxin A 358 Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 ...

  34. TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf

    ... Ochratoxin A 358 Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 ...

  35. TR-514: trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr514.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  36. TR-515: Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7... 9.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr515.pdf

    ... 482 Oxazepam (Mice) 443 Furosemide 356 Oxazepam (Rats) 468 Gallium Arsenide 492 Oxymetholone 485 Geranyl Acetate 252 Oxytetracycline Hydrochloride 315 Glutaraldehyde 490 Ozone ...

  37. TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr516.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  38. TR-519: Stoddard Solvent IIC (CASRN 64742-88-7) in F344/N Rats... 8.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr519.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  39. TR-527: Malachite Green Chloride and Leucomalachite Green (CASRNs... 7.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr527.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  40. TR-504: o-Nitrotoluene (CASRN 88-72-2) in F344/N Rats and B6C3F1... 14.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr504.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  41. TR-507: Vanadium Pentoxide (CASRN 1314-62-1) in F344/N Rats and... 6.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr507.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

  42. TR-510: Urethane + Ethanol (CASRNs. 51-79-6 & 64-17-5) in F344... 17.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr510.pdf

    ... Oleic Acid Diethanolamine Condensate 481 Oxazepam (Mice) 443 Oxazepam (Rats) 468 Oxymetholone 485 Oxytetracycline Hydrochloride 315 Ozone and Ozone/NNK 440 Penicillin VK 336 ...

 
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