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TR-553: Photococarcinogenesis Study of Aloe Vera[CASRN 481-72... 6.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr553.pdf
PHOTOCOCARCINOGENESIS STUDY OF ALOE VERA [CAS NO. 481-72-1 (Aloe-emodin)] IN SKH-1 MICE (SIMULATED SOLAR LIGHT AND TOPICAL APPLICATION STUDY) NATIONAL TOXICOLOGY PROGRAM P.O. Box ...
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Abstract for TR-553 73KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr553
CASRN: 481-72-1 Chemical Formula: C15H10O5 Molecular Weight: 270.24 Synonyms/Common Names: ... whole leaf) or creams containing aloe-emodin would enhance the photocarcinogenicity ...
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TR 577: Nondecolorized Whole Leaf Extract of Aloe Barbadensis... 11.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr577_508.pdf
... isolated from Aloe vera, including aloe-emodin, the anthraquinone of barbaloin and ... Cleavage of the β-C-glucosyl bond results in the formation of aloe-emodin, the cathartic ...
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Agenda: BSC TRRS; Feb. 27-28, 2008 36KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2008/feb/trrs27feb2008agendafnl_508.pdf
Abraham Nyska Dr. Keith Soper Dr. Tracie Bunton Dr. Raymond Novak Aloe vera and Aloe-emodin (481-72-1) Photococarcinogenicity Study TR 553 Dermal Crl:SKH-1 male and female mice Dr. ...
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GMM-15: Genetically Modified Model Report on Senna (Feed Studies... 4.0MB
https://ntp.niehs.nih.gov/ntp/htdocs/gmm_rpts/gmm15_508.pdf
... GMM 15 and sennidin B), 1,8-dihydroxy anthraquinones (rhein, aloe-emodin, emodin, and chrysophanol), aloe-emodin diglucoside, rhein glucoside, naphthalene derivatives, ...
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Minutes: BSC TRRS; Feb. 27, 2008 112KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2008/feb/trrs27feb2008mins_508.pdf
... hairless mice treated topically with aloe-emodin and exposed to SSL, the onset, ... not male mice, treated topically with aloe-
emodin creams and exposed to SSL, when ...
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RoC Background Document: Danthron; Nov. 18-19, 1996 1.9MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/danthron1_508.pdf
... Aloe-Emodin) ...... 18 ...oxy-3-hydroxy-9,10-anthracenedione (Aloe-Emodin) Emodin is practically insoluble in water. ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... No Evidence NE No Evidence NE No Evidence SE Some Evidence TR-553 02/27/08 Aloe Vera 481-72-1 TR-552 05/17/07 Propargyl Alcohol 107-19-7 SE Some Evidence NE No Evidence SE Some ...
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Public Comment: Coconut diethanolamide; Linda Loretz; RoC; Sept... 2.3MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/loretz20131016_508.pdf
... are converted to aloe emodin-9-anthrone by bacteria present in the gastrointestinal tract of rats and humans, and sequentially oxidized to aloe-emodin, which is genotoxic and ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Report TR-553 PDF (6.77 MB) Photococarcinogenesis Study of Aloe Vera [CASRN 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study) 2010 ...
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Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf
... The bark contains anthranoids, mainly of the aloe-emodin type, in addition to those of the ... Data obtained for aloe-emodin (481-72-1) are outlined in Table 5 below. Table 5. Results ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Report TR-553 PDF (6.77 MB) Photococarcinogenesis Study of Aloe Vera [CASRN 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study) 2010 ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-553 PDF (6.77 MB) Photococarcinogenesis Study of Aloe Vera [CASRN 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study) 2010 ...
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Minutes: BSC; June 12, 2008 280KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2008/june/minutes20080612.pdf
... enhancing effect in female mice exposed to aloe gel or aloe
emodin, and a weak enhancing effect in both male and female mice for the whole leaf or decolorized whole leaf extract. ...
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TR-493: Emodin (CASRN 518-82-1) in F344/N Rats and B6C3F1Mice... 18.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr493.pdf
... Res. 414, 125-129. Müller, S.O., Eckert, I., Lutz, W.K., and Stopper, H. (1996). Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: ...
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TR-568: Photocarcinogenesis Studies of Retinoic Acid and Retinyl... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr568_508.pdf
... Toxicology Program (NTP) (2010). Photococarcinogenesis Study of Aloe Vera [CAS No. 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study). ...
