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114 results found for "50-23-7".

  1. Appendix A: Overview of human studies: Cancer, biomarkers, and... 1.8MB

    https://ntp.niehs.nih.gov/ntp/roc/meetings/2016/alan/appendix_a_508.pdf

    ... In addition to melatonin, at least three studies have investigated cortisol in relation to ... (CD); four used melatonin and one used cortisol as markers of CD. Similar to shift work ...

  2. NTP Cancer Hazard Report: Night Shift Work and Light at Night... 10.1MB

    https://ntp.niehs.nih.gov/ntp/results/pubs/cancer_assessment/lanfinal20210400_508.pdf

    ... regulators of the circadian timing system (e.g., cortisol and melatonin) (see Figure 1). ... shift using levels of 6-sulfatoxymelatonin and cortisol and other sex hormones in women. ...

  3. Appendix C: Overview of human studies: Non-cancer health outcome 881KB

    https://ntp.niehs.nih.gov/ntp/roc/meetings/2016/alan/appendix_c_508.pdf

    ... The primary measurements studied were melatonin and cortisol level relation to circadian ... The effect of shift rotation on employee cortisol profile, sleep quality, fatigue, and ...

  4. Skeletal Muscle - Mineralization 389KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/musculoskeletal/skel_musc/mineral/skeletal-muscle-mineralization_508.pdf

    Dystrophic or metastatic calcification of skeletal muscle is sporadically observed as a spontaneous change; however, diet, hormonal changes, administration of hydrocortisone, and ...

  5. Monograph: Summary of NTP Cancer Hazard Conclusions: Exposure... 870KB

    https://ntp.niehs.nih.gov/ntp/results/pubs/cancer_assessment/lanfinal_summary20210400_508.pdf

    ... regulators of the circadian timing system (e.g., cortisol and melatonin) (see Figure 1). ... shift using levels of 6-sulfatoxymelatonin and cortisol and other sex hormones in women. ...

  6. Monograph: Night Shift Work and Light at Night; August 24, 2018 6.2MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph20180824.pdf

    ... 2.1.3 Other circadian biomarkers: Cortisol, core body temperature ... These include melatonin, cortisol, body temperature, and clock gene expression, which have ...

  7. Skeletal muscle - Mineralization - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/skeletal-muscle/Mineralization

    Dystrophic or metastatic calcification of skeletal muscle is sporadically observed as a spontaneous change; however, diet, hormonal changes, administration of hydrocortisone, and ...

  8. Accelerating synthetic biotic development with gut-on-a-chip... 5.8MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-12/Wksp_11_Tyler Nelson_GutModels2023_508.pdf

    ... Characterization of a Cortisol Sensing Tryptamine Producing Synbiotic for Cognitive ... SYN (E. Coli Nissle 1917 - engineered to sense cortisol and upon activation produce ...

  9. ICCVAM Recommended Protocol: Test Chemical Solubility for Neutral... 242KB

    https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invidocs/phiiiprot/solphiii.pdf

    ... of epidermal growth factor, insulin, hydrocortisone, antimicrobial agents, bovine ... factor 5 mg/mL Insulin 0.5 mg/mL Hydrocortisone 30 mg/mL Gentamicin 15 ng/mL ...

  10. Introduction and Exposure Studies of Circadian Disruption; Ruth... 1.5MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/presentations/04lunn_rocprp_508.pdf

    ... Internal synchronizer of circadian rhythms Other clock gene entrainers include cortisol ... Internal synchronizer of circadian rhythms Other clock gene entrainers include cortisol ...

  11. NTP Monograph on Health Effects of Low-Level Lead Appendix E... 2.5MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixe_final_508.pdf

    ... T, free T, urinary cortisol Observational study, comparisons made to reference values. ... , TSH, FSH, LH, PRL, T, free T, urinary cortisol, sperm count, motility, morphology, ...

  12. ICCVAM Recommended Protocol: NHK Neutral Red Uptake Assay 413KB

    https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invidocs/phiiiprot/nhkphiii.pdf

    ... of epidermal growth factor, insulin, hydrocortisone, antimicrobial agents, bovine ... factor 5 mg/mL Insulin 0.5 mg/mL Hydrocortisone 5 Test Method Protocol for the NHK ...

  13. NHK 3T3 NRU Cytotoxicity Test Method: ICCVAM Recommended Protocol 378KB

    https://ntp.niehs.nih.gov/iccvam/docs/protocols/ivcyto-nhk.pdf

    ... of epidermal growth factor, insulin, hydrocortisone, antimicrobial agents, bovine ... . 5 µg/mL Insulin . 0.5 µg/mL Hydrocortisone . 30 µg/mL Gentamicin . 15 ng/mL ...

  14. NTP Monograph on Health Effects of Low-Level Lead Appendices... 6.8MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/appendicesathrue_final_508.pdf

    ... measured using assays of salivary cortisol before and after standard cold pressor ... across quartiles: Initial salivary cortisol: Pre and postnatal Pb exposure p>0.05 ...

  15. Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf

    ... Citronellol 106-22-9 N NC 1B 1 1B Hexyl salicylate* 6259-76-3 Y NC 1 NC 1B Hydrocortisone* 50-23-7 Y NC N/A 1 1B n-Hexane 110-54-3 Y NC NC NC NC Propylene glycol* 57-55-6 Y NC NC ...

  16. RoC Protocol: Electric Light; May 7, 2018 472KB

    https://ntp.niehs.nih.gov/ntp/roc/protocols/electric-light_508.pdf

    ... rhythms measured by body temperature and cortisol shifted slowly from day to night shift ... the circadian variation of salivary melatonin and cortisol in airline flight attendants. ...

  17. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... of epidermal growth factor, insulin, hydrocortisone, antimicrobial agents, bovine ... factor 5 µg/mL Insulin 0.5 µg/mL Hydrocortisone 30 µg/mL Gentamicin 15 ng/mL ...

  18. E04: Mean Body Weights and Survival Table for Mice (20209-04... 24KB

    https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20209_tables/04e04.pdf

    Control List: Male: 001 Female: 002 Study Gender: Both TDMSE Version: 3.0.2.1_001 PWG Approval Date: NONE Experiment Number: 20209 - 04 E04: MEAN BODY WEIGHTS AND SURVIVAL TABLE ...

  19. E04: Mean Body Weights and Survival Table for Male & Female Mice... 20KB

    https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20523_tables/04_f1_m3_e04.pdf

    Control List: Male: 001 Female: 002 Study Gender: Both TDMSE Version: 3.0.2.2_002 PWG Approval Date: NONE Experiment Number: 20523 - 04 E04: MEAN BODY WEIGHTS AND SURVIVAL TABLE ...

  20. Monograph: Night Shift Work and Light at Night; Appendix A: Literature... 199KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appa.pdf

    ... A.2.5 Specific Biomarkers PubMed: (corticosterone[tiab] OR cortisol[mh] OR cortisol[tiab] OR melatonin[mh] OR melatonin[tiab] OR "body temperature"[mh] OR ...

  21. RR-12: Synthetic Turf/Recycled Tire Crumb Rubber: Characterization... 761KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr12_508.pdf

    ... Louis, MO), 15 mM HEPES a (Sigma), 0.1 μM hydrocortisone (Sigma), 5 μg/mL bovine insulin (Sigma), 5 μg/mL human transferrin (Calbiochem, San Diego, CA), and 0.2 nM ...

  22. Expert Panel Evaluation of the Validation Status of In Vitro... 1.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/expertpanfinalrpt/panelrpt1102.pdf

    ... (DHT) was provided for the MDA-MB-453 and the response to cortisol was not provided. ... Three of the protocols (B2, B5 and B6) utilize CHO cells which respond to cortisol ...

  23. Session Abstract 265KB

    https://ntp.niehs.nih.gov/ntp/roc/meetings/2016/alan/session_abstract20160311_508.pdf

    ... or melatonin and biomarkers of circadian disruption and/or early markers potentially associated with adverse health effects such as melatonin, cortisol, and sex steroid hormones. ...

  24. NTP Monograph on Health Effects of Low-Level Lead Appendix A... 2.5MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixa_final_508.pdf

    ... measured using assays of salivary cortisol before and after standard cold pressor ... across quartiles: Initial salivary cortisol: Pre and postnatal Pb exposure p>0.05 ...

  25. TR-485: Oxymetholone (CASRN 434-07-1) in F344/N Rats and Toxicology... 12.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr485.pdf

    ... serum thyroxine- binding prealbumin and cortisol-binding globulin and depression in ... Effects of anabolic steroids on hormone-binding proteins, serum cortisol and serum ...

  26. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... agent fragrance + + Kimber and Basketter (1997) Loveless et al. (1996) Hydrocortisone// Cortisol 50-23-7 steroid pharmaceutical (anti- inflammatory) - - + 0.1% pet. as 17- ...

  27. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf

    ... sulfate (DHEAS), cortisol and ferritin in neonates, children and young adults. ... Ki = 3.92 µM Ki = 18.62 µM - Martin et al., 2003 (449) ACTH-stimulated cortisol ...

  28. TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf

    ... Titanocene dichloride has been found to increase serum levels o f cortisol in pregnant as well as in nonpregnant animals (KOpf-Maier, 1985). CARCINOGENICITY In Fischer 344/N rats ...

  29. ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf

    ... was provided for the MDA-MB-453 cells, but the response to cortisol was not provided. ... Three of the protocols (B2, B5 and B6) utilize CHO cells which respond to cortisol ...

  30. Minutes: SACATM; June 18, 2010 287KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/2010/june/minutes20100618.pdf

    ... Karas said there is no gold standard for assessing pain or distress in animals, though various researchers have attempted to do so by measuring serum cortisol Minutes from the June ...

  31. OECD Guidance Document 129: Using Cytotoxicity Tests to Estimate... 1.4MB

    https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-gd129.pdf

    ... epidermal growth factor, 5 µg/mL insulin, 0.5 µg/mL hydrocortisone, 30 µg/mL gentamicin, 15 ng/mL amphotericin B, 0.10 mM calcium, and 30 µg/mL bovine pituitary extract (e.g. ...

  32. TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf

    ... When serum has been deleted, various additives including insulin and hydrocortisone have ... suppressed by greater than 70% when hydrocortisone is added to the culture medium at a ...

  33. TR-324: Boric Acid (CASRN 10043-35-3) in B6C3F1Mice (Feed Studies... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr324.pdf

    PROGRAM Technical Report Series No. 324 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BORIC ACID (CAS NO. 10043-35-3) IN B6C3Fi MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...

  34. Peer Review Report: Draft Report on Carcinogens Monograph on... 316KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2018/october/peerreview20181005_508.pdf

    ... temperature and glucocorticoid hormone (cortisol) rhythms in coordinating and resetting ... clock genes in peripheral tissues and rhythms of cortisol, the SNS, and body temperature. ...

  35. Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf

    ... Product - - Y negative for ER and AR binding and no in vivo testing planned Cortisol 50-23-7 Steroid Pharmaceutical, Veterinary Agent - - ER-/AR- ER-/AR++ AR agonist but no in ...

  36. Response to Request for Data and Information on Zebrafish Embryo... 1.6MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-26605/kanungo-508.pdf

    ... on plasma concentrations of luteinizing hormone, testosterone and cortisol in man. Br. ... TC. 1981. Serum levels of testosterone, cortisol, prolactin and bioactive luteinizing ...

  37. TR-274: Tris(2-ethylhexyl)phosphate (CASRN 78-42-2) In F344/N... 8.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr274.pdf

    4 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIS(2-ETHYLHEXYL)PHOSPHATE (CASNO. 78-42-2) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...

  38. TR-375: Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32... 20.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr375.pdf

    PROGRAM Technical Report Series No. 375 (1- <~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF VINYL TOLUENE (MIXED ISOMERS) (65%-71% META-ISOMER AND 32%-35% PARA-ISOMER) (CAS NO. ...

  39. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... 165 Isoproterenol * HCl 51-30-9 5.45 0.022 2219.8 8.96 NA NA 247.75 8.96 32 Hydrocortisone 50-23-7 7.98 0.022 NA NA NA NA 362.51 166 Triisooctylamine 2757-28-0 8.14 0.023 1620.2 ...

  40. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIETHANOLAMINE (CAS NO. 102-71-6) IN B6C3F 1 MICE (DERMAL STUDY) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC ...

  41. TR-343: Benzyl Alcohol (CASRN 100-51-6) in F344/N Rats and B6C3F1Mice... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr343.pdf

    3 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZYL ALCOHOL (CAS NO. 100-51-6) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...

  42. TR-373: Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr373.pdf

    ... 95 50 6 24 2 50 23 3 96 50 23 1 95 50 8 25 0 50 23 9 96 50 23 6 94 50 9 255 50 247 97 50 23 7 93 50 10 257 50 25 0 97 49 24 6 96 50 11 266 50 25 2 95 49 24 7 93 50 12 27 7 50 25 6 ...

  43. TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf

    TOXICOLOGY AND CARCINOGENESIS STUDIES OF dl-AMPHETAMINE SULFATE (CAS NO. 60-13-9) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...

  44. TR-497: Methacrylonitrile (CASRN 126-98-7) in F344/N Rats and... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr497.pdf

    ... Hepatocytic glycogen accumu- lation is known to occur following exposure to certain chemicals. Cortisol and other corticosteroids are impor- tant stimulants of hepatic glycogen ...

  45. TR-587: Tetrabromobisphenol A (CASRN 79-94-7) in F344/NTac Rats... 3.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr587_508.pdf

    NTP TechNical RePoRT oN The Toxicology STudieS of TeTRabRomobiSPheNol a (caSRN 79-94-7) iN f344/NTac RaTS aNd b6c3f1/N mice aNd Toxicology aNd caRciNo- geNeSiS STudieS of TeTRa- ...

  46. TR 577: Nondecolorized Whole Leaf Extract of Aloe Barbadensis... 11.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr577_508.pdf

    ... Interactions of Aloe gel have also been reported for hydrocortisone, antidiabetic agents, and UV radiation (Mascolo et al., 2004). BIOLOGICAL PROPERTIES OF ALOE VERA LATEX OR ALOE ...

  47. TR-207: Cytembena (CASRN 21739-91-3) 3.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr207.pdf

    ... ACCIDENTALLY KILLED TERMINAL SACRIFICE ANIMAL MISSING 50 9 2 2 36 50 23 6 1 20 50 23 7 1 19 50 27 10 1 12 a INCLUDES AUTOLYZED ANIMALS TUMOR SUMMARY TOTAL ANIMALS WITH ...

  48. TR-281: HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol]... 8.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr281.pdf

    1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HC RED NO. 3 [2,-((4-AMINO-2-NITROPHENY L)AMINO)ETHANOLl (CAS NO. 2871-01-4) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. ...

  49. TR-303: 4-Vinylcyclohexene (CASRN 100-40-3) in F344/N Rats and... 11.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr303.pdf

    3 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 4-VINYLCYCLOHEXENE (CAS NO. 100-40-3) IN F344/N RATS AND B6C3Ft MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...

  50. TR-309: Decabromodiphenyl Oxide (CASRN 1163-19-5) In F344/N Rats... 17.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr309.pdf

    9 TOXICOLOGY AND CARCINOGENESIS STUDIES OF DECABROMODIPHENYL OXIDE (CAS NO. 1163-19-5) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...

 
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