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155 results found for "50-32-8".
  1. Comment: Meat-related exposures (ORoC3); Shalene McNeill, The... 69KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill_3oroc20161007.pdf

    PAHs, in particular benzo[a]pyrene (BaP), and HCA content in foods, is confounded ... meats are not significant sources of BaP compared to other sources of animal protein. ...

  2. Comment: Meat-related exposures (OHAT4); Shalene McNeill, The... 70KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill_4ohat20161007.pdf

    PAHs, in particular benzo[a]pyrene (BaP), and HCA content in foods, is confounded ... meats are not significant sources of BaP compared to other sources of animal protein. ...

  3. Polycyclic Aromatic Compounds 83KB

    https://ntp.niehs.nih.gov/whatwestudy/topics/pacs

    Status: Ongoing Substances: Acenaphthenequinone Benzo(a)pyrene Pyrene ... PAC CASRN Testing Status Benzo[a]pyrene 50-32-8 Ongoing Phenanthrene 85-01-8 Ongoing ...

  4. Poster: Building a Comprehensive Search of Epigenetic Studies... 1.3MB

    https://ntp.niehs.nih.gov/ntp/results/pubs/posters/garner_sot20220327.pdf

    Widely associated with epigenetic changes As Inorganic arsenic Benzo(a)pyrene Aflatoxin B1 Background . Key characteristics of carcinogens (KCCs) are used for Report on Carcinogens ...

  5. Poster: Use of Survey Sampling to Develop an Evidence Map of... 1.7MB

    https://ntp.niehs.nih.gov/ntp/results/pubs/posters/wang_gems_20221101.pdf

    For example, epigenetic changes were studied in roughly 250 benzo(a)pyrene references , ... NIEHS is updating the benzo(a)pyrene evaluation and is assessing the potential ...

  6. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    (estradiol-17β) see Estrogens, Steroidal 50-29-3 see Dichlorodiphenyltrichloroethane 50-32-8 (benzo[a]pyrene) see Polycyclic Aromatic Hydrocarbons: 15 Listings 50-55-5 see ...

  7. TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf

    ... in Hamsters by Different Dose Levels of Benzo(a)pyrene and Ferric Oxide." £._ Natl. ... Induced by Different Numbers of Administrations of Benzo(a)pyrene and Ferric Oxide." ...

  8. Comment: Meat-related exposures; Jane Pouzou, Solenne Costard... 945KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/pouzou_costard_zagmutt20161011.pdf

    HCAs and BaP were not necessarily the same foodstuffs. Fish contributed somewhat more of MeIQx than other sources (up to 5.66 ng/g of MeIQx), 3 whereas PhIP and BaP were more ...

  9. E04: Mean Body Weights and Survival Table for Male & Female Mice... 20KB

    https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20523_tables/04_f1_m3_e04.pdf

    Control List: Male: 001 Female: 002 Study Gender: Both TDMSE Version: 3.0.2.2_002 PWG Approval Date: NONE Experiment Number: 20523 - 04 E04: MEAN BODY WEIGHTS AND SURVIVAL TABLE ...

  10. Comment: Meat-related exposures; Jerrad Legako, TTU; OHAT/ORoC... 355KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/legako20161007.pdf

    ... data, with only a very limited amount of BaP data contributed to reflect PAH. Granted, ... The same is apparent in the PAH/BaP literature. For example, in some countries "grilling" ...

  11. RoC Profile: Polycyclic Aromatic Hydrocarbons: 15 Listings; 15th... 373KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/polycyclicaromatichydrocarbons.pdf

    Also known as B[j]F Benzo[k]fluoranthene CAS No. 207-08-9 Also known as B[k]F Benzo[a]pyrene CAS No. 50-32-8 Also known as B[a]P Dibenz[a,h]acridine CAS No. 226-36-8 Also known as ...

  12. Comment: Meat-related exposures, Shalene McNeill, The Beef Checkoff... 74KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill20180911-2.pdf

    (PhIP) and 2-amino-3,8- dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 8 PAH [BaP, Chrysene (Chy), Benzo[a]Anthracene (BaA), Benzo[k]Fluoranthene (BkF), ...

  13. RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dieselexhaust_508.pdf

    ... 252 207-08-9 91-289 Benzo[a]pyrene 252 50-32-8 208-558 Benzo[e]pyrene 252 192-97-2 ... elimination rate and induction of benzo(a)pyrene hydroxylase and ethoxycoumarin de- ...

  14. National Institute of Environmental Health Sciences: Carcinogenicity... 151KB

    https://www.niehs.nih.gov/research/atniehs/dtt/strategic-plan/health/carcinogenicity

    ... Use of read across to classify carcinogenic hazard of PAHs with limited animal cancer data. Evaluation of benzo(a)pyrene, which was listed as a reasonably anticipated human ...

  15. Protocol: Systematic Review of Inflammation-based Atherosclerosis... 1001KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosisjuly2023_508.pdf

    .../exp OR "3,4-benzopyrene":ti,ab OR "benzo(a)pyrene":ti,ab OR "benzo-a-pyrene":ti,ab OR ... OR "3,4- Benz(a)pyrene":ti,ab OR "3,4-Benzo(a)pyrene":ti,ab OR "3,4-Benzofluoranthene":ti,...

  16. Protocol: Evidence Map of Inflammation-Based Atherosclerosis... 643KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosis_supplementaljuly2023_508.pdf

    .../exp OR "3,4-benzopyrene":ti,ab OR "benzo(a)pyrene":ti,ab OR "benzo-a-pyrene":ti,ab OR ... OR "3,4-benzopyrene"[tiab] OR "benzo(a)pyrene"[mh] OR "benzo(a)pyrene"[tiab] OR ...

  17. TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf

    ... obtained with benzo(a)pyrene, 3-methyl- cholanthrene, and urethane (Pietra et al., 1961). ... safrole, 4-amino- biphenyl, and benzo(a)pyrene bind to the DNA o f the maternal ...

  18. Mechanistic Insights from Profiling Chemical-Mediated Transcription... 6.9MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-medvedev-poster.pdf

    ... Benz(a)anthracene 200uM 0.90 Cupferron 66.7uM 0.90 Benz(a)anthracene 7.4uM 0.90 Benzo(a)pyrene 60uM 0.90 Cyclohexylphenylketone 66.7uM 0.90 Benz(a)anthracene 22.2uM 0.90 Day 1 Day ...

  19. TR-398: Polybrominated Biphenyls (CASRN 67774-32-7)(Firemaster... 14.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr398.pdf

    ... obtained with benzo(a)pyrene, 3-methylchotanthrene, and urethane (Pietra et al., 1961). ... safrole, 4-aminobiphenyl, and benzo(a)pyrene bind to the DNA of the maternal ...

  20. RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf

    ... C 20 H 12 199 ng/cig 44 ng/cig 50-32-8 252.31 2A Grimmer et al. (1977) 4 RoC ... ST + V79 + Benzene 71-43-2 CCC + CYI + MNT + SCE - TRM + Benzo[a]pyrene 50-32-8 CCC + CT + ...

  21. Literature Search Results: Systematic Review of Traffic-Related... 275KB

    https://ntp.niehs.nih.gov/ntp/ohat/airpollchildhealth/literature_results_508.pdf

    ... diesel[tiab] OR petrol*[tiab] OR Polycyclic hydrocarbons, aromatic[mh:noexp] OR "benzo(a)pyrene"[mh] OR benzene[mh] OR "polycyclic aromatic hydrocarbons"[tiab] OR ...

  22. TR-203: Phenol for Possible Carcinogenicity (CASRN108-95-2) 4.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr203.pdf

    ... Duuren et al. (1968) have shown that phenol in acetone or benzene promotes skin cancer in mice pretreated with 7,12-dimethylbenz(a)anthracene (DMBA) or 3,4-benzo(a)pyrene (BaP). ...

  23. Nomination Background: Wireless Communication Devices (CASRN... 153KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/wireless051999_508.pdf

    ... Of particular interest is, for example, the study conducted by Szmigielski et al (1983), who observed faster development of benzo(a)pyrene-induced skin tumors in mice that were ...

  24. Protocol for a Systematic Review of Traffic-Related Air Pollution... 1.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/airpollchildhealth/protocol_20160616_508.pdf

    ... dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene. ... hydrocarbons, aromatic[mh:noexp] OR "benzo(a)pyrene"[mh] OR benzene[mh] OR "polycyclic ...

  25. Combined Exposures and Mixtures Program; BSC; Feb. 2, 2021 277KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/february/meeting_materials/cem_bsc_508.pdf

    ... biloba extract) or constituents with established toxicological activity (e.g., benzo(a)pyrene in cookstove emissions). 20 Nontargeted chemical analysis methods can be used to ...

  26. Minutes: BSC; March 27, 1984 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf

    ... and diol formation at sites 6 0 such as the 7, 8, 9, 10-position of benzo(a)pyrene . ... activity of 1-, 3- and 6-nitrobenzo(a)pyrenes in Chinese hamster ovary (CHO) cells . ...

  27. TOX-13: Trinitrofluorenone (CASRN 129-79-3) 2.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox013.pdf

    ... It was not specified, however, if these were concurrent controls. Under similar protocols, 8/9 (89%) rats given an oral dose of 100 mg of benzo(a)pyrene developed mammary tumors; ...

  28. TR-209: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN 1746-01-6... 8.5MB

    https://ntp.niehs.nih.gov/go/tr209

    ... 72 hours prior to skin painting with benzo(a)pyrene ( B ( a ) P , 100 nmol) or with 7,12- ...3,7,8-tetrachlorodibenzo-p- dioxin on benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene ...

  29. Minutes: BSC; Sept. 27, 1983 638KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1983/september/bsc_mins19830927_508.pdf

    ... Employees, tumor initi- benzo(a)pyrene dinitropyrenes ation & promo- -Teratoloay study in mixture a s tion studies (inh .) that utilized AFL-CIO by EPA of dinitro- (H) pyrene ...

  30. TR-201: Carcinogenesis 2,3,7,8-Tetrachlorodibenzo-p-dioxin (CASRN... 5.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr201.pdf

    ... 72 hours prior to skin painting with benzo(a)pyrene (B(a)P, 100 nmol) or with 7,12-di- ...3,7,8-tetrachlorodibenzo-p- dioxin on benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene ...

  31. Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf

    ... ARC formed in tobacco smoke are ∼25- to 100-fold higher than those of 4-ABP 4 or benzo(a)pyrene, 143 and comparable to the levels of the tobacco-specific nitrosamine ...

  32. TR-565: Milk Thistle Extract (CASRN 84604-20-6) in F344/N Rats... 7.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr565.pdf

    ... hemolysates from benzo(a)pyrene-induced oxidative damage (Kiruthiga et al., 2007). ... Protective effect of silymarin on erythrocyte haemolysate against benzo(a)pyrene and ...

  33. TR-574: Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1... 13.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr574_508.pdf

    ... When 5 mg (0.04 mmol) pyrogallol and 0.005 mg benzo(a)pyrene were simultaneously applied ... The incidence of benzo(a)pyrene-induced micronuclei in mouse bone marrow was decreased ...

  34. RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf

    ... Analytical Conc. (μg/mL) Acenaphthene - 83-32-9 2001 Acenaphthylene - 208-96-8 2001 Anthracene - 120-12-7 2001 Benz(a)anthracene - 56-55-3 1995 Benzo(a)pyrene - 50-32-8 2002 ...

  35. TR-327: Xylenes (Mixed) (60%m-Xylene, 14%p-Xylene, 9%o-Xylene... 8.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr327.pdf

    ... P-450-mediated metabolism of bi- phenyl and benzo(a)pyrene in male Sprague- Dawley rats. ... organic solvents on cytochrome P-450-media- ted metabolism of biphenyl and benzo(a)pyrene. ...

  36. TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf

    ... were obtained with benzo(a)pyrene, 3-methylcholanthrene, and urethane (Pietra et al.,1%1). ... induced by the environmental carcinogens safrole, 4-aminobiphenyl, and benzo(a)pyrene. ...

  37. Minutes: BSC; March 10, 1982 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1982/march/bsc_mins19820310_508.pdf

    ... Maronpot replied that the female was more sensitive and that both diethy1nitrosamine and benzo(a)pyrene had been used and found effective as initiators . Dr . Swenberg expressed ...

  38. TR-022: Dieldrin (CASRN 60-57-1) 1.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr022.pdf

    ... Sellakumar, A. R., Cefis, F., and Kaufman, D. G., Respiratory tract carcinogenesis in hamsters induced by different numbers of administrations of benzo(a)pyrene and ferric oxide. ...

  39. TR-529: 2,2',4,4',5,5'-Hexachlorobiphenyl (PCB 153) (CASRN 35065... 7.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr529.pdf

    ... In addition to the persistent DLCs, there are a wide variety of other com- pounds that can also bind to the AhR, including poly- cyclic aromatic hydrocarbons, (e.g., benzo(a)pyrene ...

  40. TR-559: 2,3',4,4',5-Pentachlorobiphenyl (PCB 118)(CASRN 31508... 6.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr559.pdf

    ... In addition to the persistent DLCs, there are a wide variety of other com- pounds that can also bind to the AhR, including poly- cyclic aromatic hydrocarbons (e.g., benzo(a)pyrene ...

  41. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    ... Type: Notice June 13, 2018 Proposition 65 7440-48-4 TRIMVX 50-32-8 2018 EPA Asbestos; ... of the Final Public Health Goals for Benzo(A)Pyrene, Methoxychlor, and TCDD (Dioxin) In ...

  42. TR-520: 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CASRN 57465... 16.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr520.pdf

    ... In addition to the persistent DLCs, there are a wide variety of other compounds that can also bind to the AhR, including polycyclic aromatic hydrocarbons, (e.g., benzo(a)pyrene ...

  43. TR-521: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) (CASRN 1746... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr521.pdf

    ... In addition to the persistent DLCs, there is a wide variety of other compounds that can also bind to the AhR, including polycyclic aromatic hydrocarbons, (e.g., benzo(a)pyrene ...

  44. TR-525: 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CASRN 57117... 7.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr525.pdf

    ... In addition to the persistent DLCs, there are a wide variety of other com- pounds that can also bind to the AhR, including poly- cyclic aromatic hydrocarbons, (e.g., benzo(a)pyrene ...

  45. TR-526: a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD... 9.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr526.pdf

    ... In addition to the persistent DLCs, there is a wide variety of other com- pounds that can also bind to the AhR, including poly- cyclic aromatic hydrocarbons, (e.g., benzo(a)pyrene ...

  46. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... Benzo(a)anthracene 56-55-3 Natural Product carcinogenic 8.00E+06 - 3.91E+03 2.00E+01 - 9.77E-03 8.76E-05 - 4.28E-08 99% Sigma Powder Benzo(a)pyrene 50-32-8 Natural Product ...

  47. TR-017: Photodieldrin (CASRN 13366-73-9) 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr017.pdf

    ... , Sellakumar, A. R., Cefis, F., and Kaufman, D. G., Respiratory tract carcinogenesis in hamsters induced by different numbers of administrations of benzo(a)pyrene and ferric oxide. ...

  48. TR-050: Acetohexamide (CASRN 968-81-0) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr050.pdf

    ... Sellakumar, A. R., Cefis, F., and Kaufman, D. G. , Respiratory tract carcinogenesis in hamsters induced by different numbers of administrations of benzo(a)pyrene and ferric oxide. ...

  49. TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr415.pdf

    ... Intratracheal instillation of a mixture o f benzo(a)pyrene and polysorbate $0 into hamsters resulted in respiratory tract neoplasms in 12 o f 50 treated animals, while neoplasms ...

  50. TR-530: a Binary Mixture of 3,3',4,4',5-Pentachlorobiphenyl ... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr530.pdf

    ... In addition to the persistent DLCs, there are a wide variety of other com- pounds that can also bind to the AhR, including poly- cyclic aromatic hydrocarbons, (e.g., benzo(a)pyrene ...

 
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