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Testis - Fibrosis - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/Fibrosis
Testicular fibrosis is induced in rats by chronic cocaine or cadmium administration. ... J. 1994. Testicular lesions by chronic administration of cocaine in rats. ...
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Testis - Fibrosis 697KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/testis/fibrosis/testis-fibrosis_508.pdf
Testicular fibrosis is induced in rats by chronic cocaine or cadmium administration. ... J. 1994. Testicular lesions by chronic administration of cocaine in rats. ...
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CERHR Monograph: Methylphenidate 11.6MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/methylphenidate/methylphenidatemonograph.pdf
... drugs. such. as. cocaine;. emergency. department. mentions. for. methylphenidate. in. the. Drug.Abuse.Warning.Network.are.1/40 th .of.those.for.cocaine.(reviewed.in.(22)). ...
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Eye, Retina - Hemorrhage - Nonneoplastic Lesion Atlas 289KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Retina-Hemorrhage
Silva-Araújo AL, Tavares MA, Patacao MH, Carolino RM. 1996. Retinal hemorrhages associated with in utero exposure to cocaine: Experimental and clinical findings. Retina ...
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Eye, Retina - Hemorrhage 285KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/rthemor/eye-retina-hemorrhage_508.pdf
.../summary Silva-Araújo AL, Tavares MA, Patacao MH, Carolino RM. 1996. Retinal hemorrhages associated with in utero exposure to cocaine: Experimental and clinical findings. ...
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CERHR Monograph: Amphetamines 4.1MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf
.../day.amphetamine,.or.20.mg/kg.bw/day.cocaine. for.7.days.in.adult.(60-day-old),.periad... Findings.in.cocaine-treated.groups.were.similar.except.that.cocaine.treatment.significantl...
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NTP Monograph on Health Effects of Low-Level Lead Appendices... 6.8MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/appendicesathrue_final_508.pdf
... children from cohort study of prenatal cocaine; recruited at birth Year = 1994-1996 ... at birth, race, log of prenatal cocaine and alcohol average Regression of blood ...
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NTP Monograph on Health Effects of Low-Level Lead Appendix E... 2.5MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixe_final_508.pdf
... Cross-sectional Neuspiel (1994) New York 581 women giving birth at a public hospital in New York; 18 were cocaine-exposed and 46 were referents; Year=1992 Maternal age Cocaine=30.5 ...
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US Strategic Roadmap Goal: Encourage the Use and Adoption of... 3.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2018/september/presentations/02berridge_508.pdf
... Contrast dye Diuretics Loops, t hiazides Triamtere ne (Dyre nium) Drugs of abuse Cocaine, he roin, ketamine (Keta lar), methadone, methamphetamine He rba ls Chinese herbals w ...
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Monograph on Potential Human Reproductive and Developmental Effects... 2.4MB
https://ntp.niehs.nih.gov/ntp/ohat/fluoxetine/fluoxetine_monograph.pdf
... a study to determine mechanisms of cocaine-induced behavioral alterations in rats (147). ... A control group of 12 dams received 0.9% saline by s.c. injection. [Cocaine, the primary ...
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TR-380: l-Epinephrine Hydrochloride (CASRN 55-31-2) in F344/N... 21.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr380.pdf
... Gilbert et al. (1976) showed that cocaine (5 X 10-7 M), a re- uptake inhibitor, ... M.O.; Bruyere, H.J. (1976) Effects of cocaine in the production of cardiovascular ...
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TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf
... Pulmonary talc granulomatosis was diagnosed in a cocaine sniffer (Oubeid et af., 1990). ... Ingram, E.A., and Scott, G.C. (1990). Pulmonary talc granulomatosis in a cocaine sniffer. ...
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RoC Background Document for Hepatitis C Virus; June 11, 2003 2.1MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/hcv_rg2public_508.pdf
... Increased prevalence of HCV infection was associated with a history of cocaine or ... were illegal drug use (ever having used cocaine or ≥ 100 lifetime uses of marijuana) ...
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TR-446: 1-Trans-Delta9-Tetrahydrocannabinol (CASRN 1972-08-3... 16.4MB
https://ntp.niehs.nih.gov/go/tr446
... In Physiopathology of Illicit Drugs: Cannabis, Cocaine, Opiates. Advances in the ... In Physiopathology ofIllicit Drugs: Cannabis, Cocaine, Opiates. Advances in the ...
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TR-325: Pentachloronitrobenzene (CASRN 82-68-8) in B6C3F1Mice... 6.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr325.pdf
5 TOXICOLOGY AND CARCINOGENESIS STUDIES OF PENTACHLORONITROBENZENE (CAS NO. 82-68-8) IN B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...
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RoC Monograph: Kaposi Sarcoma-Associated Herpesvirus; August... 1.3MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/kshv_final201608_508.pdf
... Few studies have investigated the role of recreational drugs with immunomodulatory properties. In one prospective study, prior use of marijuana, amyl nitrate "poppers," cocaine, or ...
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Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf
... The actions were antagonized by propranolol but not by pretreatment with reserpine, cocaine, butoxamine, or phenoxybenzamine, which indicated that the selective actions were ...
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Draft RoC Monograph Kaposi sarcoma-associated herpesvirus (KSHV... 1.3MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/december/kshv_peer_draft_monograph.pdf
... Few studies have investigated the role of recreational drugs with immunomodulatory properties. In one prospective study, prior use of marijuana, amyl nitrate "poppers," cocaine, or ...
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RoC Background Document for Nitromethane; March 25, 2002 1.2MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/nmpub_no_appendices_508.pdf
... production promoted by rat nasal cytochrome P-450-dependent monooxygenases with nasal decongestants, essences, solvents, air pollutants, nicotine, and cocaine as substrates. ...
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RoC Monograph Peer Review: Kaposi Sarcoma-Associated Herpesvirus... 1.3MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_kshv.pdf
... Few studies have investigated the role of recreational drugs with immunomodulatory properties. In one prospective study, prior use of marijuana, amyl nitrate "poppers," cocaine, or ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIETHANOLAMINE (CAS NO. 102-71-6) IN B6C3F 1 MICE (DERMAL STUDY) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC ...
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TR-478: Diethanolamine (CASRN 111-42-2) in F344/N Rats and B6C3F1Mice... 10.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr478.pdf
OF DIETHANOLAMINE (CAS NO. 111-42-2) IN F344/N RATS AND B6C3F MICE 1 (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 July 1999 NTP TR ...
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TR-480: Lauric Acid Diethanolamine Condensate (CASRN 120-40-1... 8.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr480.pdf
LAURIC ACID DIETHANOLAMINE CONDENSATE (CAS NO. 120-40-1) IN F344/N RATS AND B6C3F MICE 1 (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC ...
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TR-497: Methacrylonitrile (CASRN 126-98-7) in F344/N Rats and... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr497.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF METHACRYLONITRILE (CAS NO. 126-98-7) IN F344/N RATS AND B6C3F 1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY ...
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TR-310: Marine Diesel Fuel (NO CAS) and JP-5 Navy Fuel (CASRN... 10.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr310.pdf
10 TOXICOLOGY AND CARCINOGENESIS STUDIES OF MARINE DIESEL FUEL AND JP-5 NAVY FUEL (CAS NO. 8008-20-6) IN B6C3F1 MICE (DERMAL STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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TR-490: Glutaraldehyde (CASRN 111-30-8) in F344/N Rats and B6C3F1Mice... 10.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr490.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF GLUTARALDEHYDE (CAS NO. 111-30-8) IN F344/N RATS AND B6C3F MICE 1 (INHALATION STUDIES) NATIONAL TOXICOLOGY ...
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TR-580: β-Picoline (CASRN 108-99-6) in F344/N Rats and B6C3F1... 2.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr580_508.pdf
... 50 29 232 49 229 99 50 230 99 50 215 93 50
36 248 49 248 100 50 248 100 50 234 94 50 43 ... 22.3 50 22.7 102 50 22.1 99 50 21.5 96 50
36 23.4 50 23.4 100 50 22.7 97 50 22.4 96 50 ...
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TR-584: Indole-3-Carbinol (CASRN 700-06-1) in F344/N Rats and... 4.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr584_508.pdf
... 50 29 202 50 203 100 50 198 98 50 197 97 50
36 213 50 212 100 50 206 97 50 205 96 50 43 ... 27.0 50 27.7 103 50 27.4 101 50 27.3 101 50
36 28.8 50 29.5 103 50 29.3 102 50 28.9 100 50 ...
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TR-338: Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr338.pdf
8 TOXICOLOGY AND CARCINOGENESIS STUDIES OF ERYTHROMYCIN STEARATE (CAS NO. 643-22-1) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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TR-339: 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr339.pdf
9 (/~ ..~r- TOXICOLOGY AND CARCINOGENESIS STUDIES OF 2-AMIN0-4-NITROPHENOL (CAS NO. 99-57-0) IN F344/N RATS AND B6C3FI MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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TR-345: Roxarsone (CASRN 121-19-7) in F344/N Rats and B6C3F1... 25.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr345.pdf
... 32 9 100 50 14 33 3 50 324 97 50 32 7 98 50 19 34 7 50 34 6 100 49 351 101 49 24 35 0 50 36 2 103 49 37 1 106 48 28 35 5 50 36 6 103 49 37 8 106 48 33 36 0 49 36 4 101 49 38 5 107 ...
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TR-347: d-Limonene (CASRN 5989-27-5) in F344/N Rats and B6C3F1Mice... 9.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr347.pdf
7 4 "^,oC C Z» TOXICOLOGY ANDCARCINOGENESIS STUDIES OF d-LIMONENE (CAS NO. 5989-27-5) IN F344/N RATS AND B6C3Fi MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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TR-365: Pentaerythritol Tetranitrate (CASRN 78-11-5) with 80D... 22.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr365.pdf
No. 365 ("'l /<~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF PENTAERYTHRITOL TETRANITRATE (CAS NO. 78-11-5) WITH 80% o-LACTOSE MONOHYDRATE (PETN, NF) IN F344/N RATS AND B6C3FI MICE ...
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TR-464: Technical Grade Sodium Xylene Sulfonate (CASRN 1300-72... 9.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr464.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TECHNICAL GRADE SODIUM XYLENESULFONATE (CAS NO. 1300-72-7) IN F344/N RATS AND B6C3F MICE 1 (DERMAL STUDIES) ...
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NTP Monograph on Health Effects of Low-Level Lead Appendix A... 2.5MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixa_final_508.pdf
... children from cohort study of prenatal cocaine; recruited at birth Year = 1994-1996 ... at birth, race, log of prenatal cocaine and alcohol average Regression of blood ...
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TR-307: Ephedrine Sulfate (CASRN 134-72-5) in F344/N Rats and... 11.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr307.pdf
... Oradell, NJ: Medical Economics Co. 33. Peterson, D.; Hardinge, M. (1967) The effect of various environmental factors on cocaine and ephedrine toxicity. J. Pharm. Pharmacol. ...
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TR-356: Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr356.pdf
6 TOXICOLOGY AND CARCINOGENESIS STUDIES OF FUROSEMIDE (CAS NO. 54-31-9) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT O F HEALTH AND HUMAN SERVICES Public Health ...
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TR-357: Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and... 12.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr357.pdf
7 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HYDROCHLOROTHIAZIDE (CAS NO. 58-93-5) IN F344/N RATS AND B6C3Fi MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...
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TR-482: Furfural Alcohol (CASRN 98-00-0) in F344/N Rats and B6C3F1... 27.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr482.pdf
FURFURYL ALCOHOL (CAS NO. 98-00-0) IN F344/N RATS AND B6C3F MICE 1 (INHALATION STUDIES) February 1999 NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 ...
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TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB
https://ntp.niehs.nih.gov/go/tr349
... 97 49 38 333 3S 34 0 102 50 328 98 49 42 357 33 354 99 50 344 96 49 46 37 0 33 363 98 50 36 2 98 49 50 366 33 37 6 103 50 343 94 49 57 376 33 383 102 49 363 97 48 61 37 7 33 387 ...
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TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf
... 50 20.8 104.3 50 29 20.7 50 20.7 100.0 50 20.7 100.2 50 21.3 102.9 50 21.3 103.1 50
36 21.5 50 21.4 99.6 50 21.4 99.7 50 22.0 102.3 50 22.1 102.9 50 43 22.2 50 22.2 100.1 50 ...
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TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf
4 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 5,5=DIPHENYLHYDANTOIN (PHENYTOIN) (CAS NO. 57-41-0) IN F344/N RATS AND B6C3Fl MICE (FEEDSTUDIES) U . S . DEPARTMENT OF HEALTH AND ...
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TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf
... Nutr. 45, 252-260. Methylphenidate Hydrochloride, NTP TR 439 Ravitz, A.J., and Moore, ICE. (1977). Effects of amphetamine, methylphenidate and cocaine on serum prolactin ...
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TR-473: Theophylline (CASRN 58-55-9) in F344/N Rats and B6C3F1Mice... 11.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr473.pdf
OF THEOPHYLLINE (CAS NO. 58-55-9) IN F344/N RATS AND B6C3F MICE 1 (FEED AND GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 August 1998 ...
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TR-495: Sodium Nitrite (CASRN 7632-00-0) IN F344/N Rats and B6C3F1Mice... 16.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr495.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM NITRITE (CAS NO. 7632-00-0) IN F344/N RATS AND B6C3F 1 MICE (DRINKING WATER STUDIES) NATIONAL ...
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TR-512: Elmiron (CASRN 37319-17-8) in F344/N Rats and B6C3F1Mice... 12.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr512.pdf
ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF ELMIRON ® (CAS NO. 37319-17-8) IN F344/N RATS AND B6C3F 1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 ...
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TR-542: Cumene (CASRN 98-82-8) in F344/N Rats and B6C3F1 Mice... 9.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr542.pdf
... 50 22.3 101 50 22.5 102 50 22.6 102 50 29 23.3 50 23.4 101 50 23.6 101 50 23.7 102 50
36 24.4 50 24.5 100 50 24.6 101 50 24.8 102 50 43 25.2 50 25.5 101 50 25.6 101 50 25.7 102 ...
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TR-594: p-Chloro-α,α,α-trifluorotoluene (CASRN 98-56-6) in... 4.3MB
https://ntp.niehs.nih.gov/go/tr594
of P-chloRo-α,α,α- TRifluoRoTolueNe (casRN 98-56-6) iN sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs aNd B6c3f1/N Mice (iNhalaTioN sTudies) NTP TR 594 JUNE 2018 NTP ...
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TOX-79: Genistein (CASRN 446-72-0) 2.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox079.pdf
... Neuroscience 54, 1001-1018. Maecker, H.L. (1993). Perinatal cocaine exposure inhibits the development of the male SDN. Brain Res. Dev. Brain Res. 76, 288-292. Medina, F., Siddiqui, ...
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Public Comment on 81 FR 42718: C. Elegans Models for Developmental... 2.0MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/hunt-81fr42718.pdf
... Genetics 186, 929-941, doi: 10.1534/genetics.110.118877 (2010). 17. Ward, A., Walker, V. J., Feng, Z. & Xu, X. Z. Cocaine modulates locomotion behavior in C. elegans. PLoS One 4, ...