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Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf
Category*** 5-Fluorouracil 3 NA D 6-Mercaptopurine 3 NA D 6-Thioguanine NA NA D ... OR "5 fluorouracil" OR "6 mercaptopurine" OR "6 thioguanine" OR Abraxane OR ...
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NTP Monograph: Developmental Effects and Pregnancy Outcomes Associated... 23.8MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/chemopregnancy_monofinal_508.pdf
......... 42 5.3 6-Mercaptopurine ......Table 20: Pharmacology of 6-mercaptopurine in adult humans ......
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OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1018KB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201510_508.pdf
... OR "5 fluorouracil"[tiab] OR "6 mercaptopurine"[tiab] OR "6 thioguanine"[tiab] OR ... OR "5 fluorouracil" OR "6
mercaptopurine" OR "6 thioguanine" OR abraxane OR ...
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OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1.1MB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201812_508.pdf
... OR "5 fluorouracil"[tiab] OR "6
mercaptopurine"[tiab] OR "6 thioguanine"[tiab] OR ... OR "5 fluorouracil" OR "6
mercaptopurine" OR "6 thioguanine" OR abraxane OR ...
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Minutes: MPRP; Oct. 1-2, 2012 559KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2012/october/minutes20121002_508.pdf
... Second reviewer Dr. Lawrence had no comments on 5-fluorouracil. Anti-metabolites: 6-Mercaptopurine First reviewer Dr. Polifka noted an error in the section on human gestational ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... Hexachlorophene 0.0079 0.15 61.0 21 6-Mercaptopurine 0.008 1.84 280.0 158 Dichlorophene ... Flufenamic acid 0.029 0.97 272.8 21 6-Mercaptopurine 0.008 1.84 280.0 260 Coumarin 1.71 2 ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... 38 Hexachlorophene 70-30-4 3.21 0.0079 61.0 0.15 65.1 0.16 406.89 0.15 21 6-
Mercaptopurine 50-44-2 1.22 0.008 NA NA 280.0 1.84 152.19 1.84 158 Dichlorophene 97-23-4 2.23 0.0083 ...
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TR-281: HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol]... 8.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr281.pdf
1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HC RED NO. 3 [2,-((4-AMINO-2-NITROPHENY L)AMINO)ETHANOLl (CAS NO. 2871-01-4) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. ...
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TR-466: Ethylbenzene (CASRN 100-41-4) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr466.pdf
... 96 50 36 257 47 245 95 50 243 94 50 246 96 50 40 266 47 255 96 50 252 95 50 252 95 50
44 276 47 260 94 50 262 95 50 253 92 50 48 287 46 270 94 50 269 94 50 269 94 50 52 297 46 ...
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NTP Monograph: Systematic Review of Occupational Exposure to... 6.2MB
https://ntp.niehs.nih.gov/ntp/ohat/oeccaaho/mgraph/occchemo_final20190300_508.pdf
... OR "5 fluorouracil"[tiab] OR "6 mercaptopurine"[tiab] OR "6 thioguanine"[tiab] OR ... OR "5 fluorouracil" OR "6 mercaptopurine" OR "6 thioguanine" OR abraxane OR ...
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TR-317: Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats... 10.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr317.pdf
PROGRAM Technical Report Series No. 317 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHLORPHENIRAMINE MALEATE (CAS NO. 113-92-8) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. ...
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TR-487: Isobutene (CASRN 115-11-7) in F344/N Rats and B6C3F1Mice... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr487.pdf
ISOBUTENE (CAS NO. 115-11-7) IN F344/N RATS AND B6C3F MICE 1 (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 December 1998 NTP TR ...
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TR-535: 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr535.pdf
4-METHYLIMIDAZOLE (CAS NO. 822-36-6) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 January 2007 NTP TR ...
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TR-420: Triamterene (CASRN 396-01-0) in F344/N Rats and B6C3F1Mice... 20.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr420.pdf
Program (NTP) is made up of four charter agencies o f the U.S. Department of Health and Human Services (DHHS): the National Cancer Institute (NCI), National Institutes o f Health; ...
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TR-552: Propargyl Alcohol (CASRN 107-19-7) in F344/N Rats and... 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr552.pdf
PROPARGYL ALCOHOL (CAS NO. 107-19-7) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 September 2008 ...
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TR-554: 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344... 7.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr554.pdf
5-(HYDROXYMETHYL)-2-FURFURAL (CAS NO. 67-47-0) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 June 2010 ...
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TR-430: C.I. Direct Blue 218 (CASRN 28407-37-6) in F344/N Rats... 16.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr430.pdf
0 TOXICOLOGY AND CARCINOGENESIS STUDIES OF C.I. DIRECT BLUE 218 (CAS NO. 28407-37-6) IN F344/N RATS AND B6C3Fl MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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TR-566: Diethylamine (CASRN 109-89-7) in F344/N Rats and B6C3F1... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr566.pdf
... 50 29 206 50 210 102 50 214 104 50 205 99 50 37 226 50 230 102 50 235 104 50 225 100 50
44 239 50 244 102 50 250 105 50 239 100 50 51 253 50 258 102 50 265 105 50 253 100 50 58 ...
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TR-587: Tetrabromobisphenol A (CASRN 79-94-7) in F344/NTac Rats... 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr587_508.pdf
NTP TechNical RePoRT oN The Toxicology STudieS of TeTRabRomobiSPheNol a (caSRN 79-94-7) iN f344/NTac RaTS aNd b6c3f1/N mice aNd Toxicology aNd caRciNo- geNeSiS STudieS of TeTRa- ...
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RoC Background Document: Cyclosporin A; Nov. 18-19, 1996 4.9MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cyclosporin_a1_508.pdf
... Patients received cyclosporin A and 6-mercaptopurine. KS stabilized, or almost healed in 3/4 patients after cyclosporin was reduced or removed from their therapy. The fourth ...
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TR-579: N,N-Dimethyl-P-Toluidine (CASRN 99-97-8) in F344/N Rats... 11.5MB
https://ntp.niehs.nih.gov/go/tr579
N,N-DIMETHYL-p-TOLUIDINE (CAS NO. 99-97-8) IN F344/N RATS AND B6C3F1/N MICE (GAVAGE STUDIES) National Toxicology Program P.O. Box 12233 Research Triangle Park, NC 27709 September ...
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TR-289: Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1Mice... 16.4MB
https://ntp.niehs.nih.gov/go/tr289
... rUMORS 50* 2 50* 9 1 50 7 8 12 48 50 49 1 40 1 21 50 1 50 50 6 17 1 2 1 50 50« 48 50
44
2 1 1 40 49 50 1 1 43 42 49 7 49 1 23 50* 50 1 50 29 1 18 50 49 13 40 4 50» 1 1 50* 1 1 ...
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CERHR Monograph: Hydroxyurea 3.6MB
https://ntp.niehs.nih.gov/ntp/ohat/hydroxyurea/humonograph20090401.pdf
... Platzek and Schwabe (1999), support not indicated, examined prenatal toxicity in mice exposed to hydro- xyurea alone and combined with 6-mercaptopurine. On GD 11 (GD 0 5 24 hr ...
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TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf
... Natural Products Actinomycin-D Bleomycin Vincristine Antimetabolites Methotrexate 6-Mercaptopurine Miscellaneous Synthetics Hycanthone 5-aza-C Tilorone Chromosomal Damage In A(T 1 ...
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TR-392: Chlorinated Water (CASRNs. 7782-50-5 and 7681-52-9) and... 75.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr392.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 392 ~ Sl'gvlc~.¢. o S ~r~ ~ ~ - ~ . _ ~ %~o~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHLORINATED WATER (CAS NOS. ...