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49 results found for "50-55-5".
  1. TR-193: Reserpine (CASRN 50-55-5) 3.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr193.pdf

    3 NTP No. 80-16 BIOASSAY OF RESERPINE FOR POSSIBLE CARCINOGENICITY CAS No. 50-55-5 NCI-CG-TR-193 NTP-80-16 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...

  2. RoC Profile: Reserpine; 15th RoC 2021 131KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/reserpine.pdf

    Reserpine CAS No. 50-55-5 Reasonably anticipated to be a human carcinogen First listed in the Second Annual Report on Carcinogens (1981) Also known as methyl 18β-hydroxy-11,17α-d...

  3. Reserpine: Target Organs and Levels of Evidence for TR-193 57KB

    https://ntp.niehs.nih.gov/data/tr/100s/tr193levels

    7 Reserpine: Target Organs and Levels of Evidence for TR-193 Bioassay of Reserpine for Possible Carcinogenicity (CASRN 50-55-5) Chemical (Study Title) CASRN Peer Review Date Route/...

  4. Abstract for TR-193 61KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr193

    3abs Abstract for TR-193 Bioassay of Reserpine for Possible Carcinogenicity (CAS No. 50-55-5) CASRN: 50-55-5 Chemical Formula: C33H40N2O9 Molecular Weight: 608.684 Report Date: ...

  5. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    50-32-8 (benzo[a]pyrene) see Polycyclic Aromatic Hydrocarbons: 15 Listings 50-55-5 see Reserpine 51-52-5 see Propylthiouracil 51-79-6 see Urethane 52-24-4 see Thiotepa 53-16-7 ...

  6. Ear - Inflammation - Nonneoplastic Lesion Atlas 297KB

    https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/ear/Inflammation

    ... National Toxicology Program. 1982. NTP TR-193. Bioassay of Reserpine for Possible Carcinogenicity (CAS No. 50-55-5). NTP, Research Triangle Park, NC. Abstract: https://...

  7. Ear - Inflammation 436KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/ear/inflamm/ear-inflammation_508.pdf

    .../doi/10.1097/01.mlg.0000147930.29261.51/full National Toxicology Program. 1982. NTP TR-193. Bioassay of Reserpine for Possible Carcinogenicity (CAS No. 50-55-5). ...

  8. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... chloroprene, N-methyl-o -acrylamide, reserpine, and methylphenidate, as was the ... of the transgenic systems -- glycidol, chloroprene, N-methylolacrylamide, and reserpine. ...

  9. Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf

    ... M-PA; **; 2G inhibits T3/T4 synthesis; being tested in vivo by EPA and by OECD Reserpine 50-55-5 Heterocyclic Compound, Indole Pharmaceutical, Veterinary Agent † - - Y IM ...

  10. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... Progesterone 1,3-Propane Sultone β-Propiolactone Propylene Oxide Propylthiouracil Reserpine Riddelliine Safrole Selenium Sulfide Streptozotocin (see Nitrosourea Chemotherapeutic ...

  11. TR-051: Tolazamide (CASRN 1156-19-0) 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr051.pdf

    ... 139-65-1) ethionamide (CAS 536-33-4) reserpine (CAS 50-55-66) MICE Feed Studies ... 139-65-1) ethionamide (CAS 536-33-4) reserpine (CAS 50-55-6) Gavage Studies cholesterol ...

  12. NICEATM Update 5.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2020/ppt/04-niceatm-kleinstreuer-508.pdf

    ... Tamoxifen Diethylstilbestrol Gentian Violet Fluorouracil Bisphenol A Reserpine Leveraging human cell-based in vitro systems COVID-19 Therapeutic Work . HEK293 and MVECs . ...

  13. Update on NICEATM Computational Resources 6.6MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2021/ppt/2021_sacatm_s4-1_kleinstreuer_v2_508.pdf

    ... Cyfluthrin Spironolactone Linuron Cycloheximide Estrone 17alpha-Estradiol Reserpine Se&rdl, 2, 2' ,4,4' -Tetrahydroxybenzophenone Hydroxyflutamide Search Results: Table ...

  14. TR-296: Tetrakis(hydroxymethyl)phosphonium sulfate (THPS) (CASRN... 16.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr296.pdf

    ... BODY WEIGHTS AND CLINICAL SIGNS ...... SURVIVAL ...... 50 50 55 5 THPS and THPC. NTP TR 296 ...

  15. ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf

    ... Pharmaceutical Propylthiouracil 51-52-5 Pyrimidine; Uracil Pharmaceutical Reserpine 50-55-5 Heterocycle; Yohimban Pharmaceutical Sodium azide 26628-22-8 Organic salt; Azide ...

  16. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... 3,4,5-trimethoxybenzoate (ester) see Reserpine 2-methylbenzenamine see o-Toluidine ... ester, (3β,16β,17α,18β,20α)- see Reserpine Z (Z)-1,3-dichloropropene see ...

  17. TR-060: Phenesterin (CASRN 3546-10-9) 4.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr060.pdf

    ... (CAS 80-08-0) 4,4'-thiodianiline (CAS 139-65-1) ethionamide (CAS 536-33-4) reserpine (CAS 50-55-5) Gavage Studies estradiol bis((p-(bis(2-chloroethyl)amino)phenyl)acetate) ...

  18. TR-049: Acronycine (CASRN 7008-42-6) 5.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr049.pdf

    ... (CAS 80-08-0) 4,4'-thiodianiline (CAS 139-65-1) ethionamide (CAS 536-33-4) reserpine (CAS 50-55-5) Gavage Studies cholesterol (p-(bis(2-chloroethyl)amino)phenyl)acetate ...

  19. TR-299: C.I. Disperse Blue 1 (A commercial dye containing approximatel... 15.0MB

    https://ntp.niehs.nih.gov/go/tr299

    ... at Southern Research Institute Reserpine C ytembena Eugenol Stannous chloride ... at Southern Research Institute Reserpine Cytembena Eugenol Stannous chloride ...

  20. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... 3,4,5-trimethoxybenzoate (ester) see Reserpine 2-methylbenzenamine see o-Toluidine ... ester, (3β,16β,17α,18β,20α)- see Reserpine Z (Z)-1,3-dichloropropene see ...

  21. TR-307: Ephedrine Sulfate (CASRN 134-72-5) in F344/N Rats and... 11.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr307.pdf

    ... that pretreatment of cats with reserpine markedly reduces the pe- ripheral ... de la Sierra, B. (1962) Modification by reserpine of the action of sympathomimetic amines ...

  22. NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf

    ... 4 Procymidone NEG (1/1) NEG (1/1) NEG 4 Reserpine NEG (1/1) NT NEG 4 Spironolactone NEG ... 4 Procymidone POS (1/1) NEG (1/1) NEG 4 Reserpine POS (1/1) NEG (1/1) NEG NICEATM DRAFT ...

  23. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Clear Evidence P Clear Evidence N No Evidence P Clear Evidence TR-193 05/01/79 Reserpine 50-55-5 P Clear Evidence N No Evidence P Clear Evidence P Clear Evidence TR-192 05/01/79 ...

  24. TR-271: HC Blue No. 1 (CASRN 2784-94-3) in F344/N Rats and B6C3F1Mice... 10.0MB

    https://ntp.niehs.nih.gov/go/tr271

    ... at Southern Research Institute Reserpine Cytembena Eugenol Stannous chloride ... Historical Incidence a t Southern Research Institute Reserpine Cytembena Eugenol Stannous ...

  25. TR-567: Ginseng (CASRN 50647-08-0) in F344/N Rats and B6C3F1... 6.7MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr567.pdf

    ... Some products sold as ginseng contain Man- dragora officinarum, with hyoscine; Rauwolfia ser- pentina, with reserpine; and Cola, with caffeine. Some products were adulterated with ...

  26. TR-439: Methylphenidate Hydrochloride (CASRN 298-59-9) in F344... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr439.pdf

    ... Another differ- ence between amphetamine and methylphenidate is that reserpine antagonizes methylphenidate effects but not thoseof amphetamine (Patrick et al., 1987). A s ...

  27. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... 99% 99% Sigma Sigma Sigma Sigma Sigma Powder Powder Powder Powder Powder Reserpine Spironolactone 50-55-5 52-01-7 Heterocycle; Yohimban Steroid, nonphenolic; Pregnene lactone ...

  28. TR-293: HC Blue No. 2 [2,2'-((4-((2-Hydroxyethyl)amino)-3-nitrophenyl... 8.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr293.pdf

    ... at Southern Research Institute Reserpine 0/49 0/49 0/49 Cytembena 0/50 1150 1/50 ... at Southern Research Institute Reserpine 3/48 1148 Cytembena 11/48 0/48 Eugenol ...

  29. Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf

    ... 99% 99% Sigma Sigma Sigma Sigma Sigma Powder Powder Powder Powder Powder Reserpine Spironolactone 50-55-5 52-01-7 Heterocycle; Yohimban Steroid, nonphenolic; Pregnene lactone ...

  30. Minutes: BSC TRRS; Dec. 9, 1997 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1997/dec/trrs9dec1997mins_508.pdf

    ... The non-mutagenic carcinogens, N- methyl-o-acrylamide, reserpine, and methylphenidate, were negative in these studies. Thus, Dr. French said that it was no surprise that for six of ...

  31. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... 1980 Technical Report TR-193 PDF (3.49 MB) Bioassay of Reserpine for Possible Carcinogenicity (CASRN 50-55-5) 1982 Technical Report TR-192 PDF (2.22 MB) Bioassay of ...

  32. Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf

    ... The actions were antagonized by propranolol but not by pretreatment with reserpine, cocaine, butoxamine, or phenoxybenzamine, which indicated that the selective actions were ...

  33. Minutes: BSC; March 27, 1984 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf

    ... Zearalenone, Cyclophosphamide, Retinoic Acid, Reserpine, Propranolol Agent GB, Agent GD, Ultrasound, Silicone, d-Amphetamine . Methylmercury, Vitamin A, Aflatoxin METHODS ...

  34. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Long-Term Carcinogenicity TR-193 PDF (3.49 MB) Bioassay of Reserpine for Possible Carcinogenicity (CASRN 50-55-5) 1982 Long-Term Carcinogenicity TR-192 PDF (2.22 MB) Bioassay of ...

  35. ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf

    ... 82640-04-8 Hydrocarbon (Cyclic) Pharmaceutical 100.0 Sigma-Aldrich Corporation Reserpine 50-55-5 Heterocyclic Compound, Indole Pharmaceutical, Veterinary Agent 98.0 Sigma-Aldrich ...

  36. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... 1980 Technical Report TR-193 PDF (3.49 MB) Bioassay of Reserpine for Possible Carcinogenicity (CASRN 50-55-5) 1982 Technical Report TR-192 PDF (2.22 MB) Bioassay of ...

  37. TR-356: Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr356.pdf

    ... Institute studie!; include benzene (NTP, 1986), reserpine (NCI, 1982), 1,2-dibromoethane ... Cancer Institute (NCI) (1982) Bio- assay of Reserpine for Possible Carcinogenicity. ...

  38. CERHR Monograph: Amphetamines 4.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf

    ... Additional.drug.interactions.are.discussed.in.labels.for.d,l-.and.d-amphetamine..Gastrointestinal. acidifying.agents.(e.g.,.guanethidine,.reserpine,.glutamic.acid.HCl,.ascorbic.aci...

  39. TR-223 Carcinogenesis Studies of Eugenol (CASRN 97-53-0) in F344... 6.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr223.pdf

    ... MALE B6C3Fi MICE Chemical Eugenol Reserpine Cytembena Mannitol Ziram Propyl Gallate ... Chemical l Eugeno Eugenol l Reserpin Reserpine e Cytemben Cytembena a Mannito Mannitol ...

  40. TR-558: 3,3',4,4'-Tetrachloroazobenzene (TCAB) (CASRN 14047-09... 22.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr558.pdf

    REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF 3,3N,4,4N-TETRACHLOROAZOBENZENE (TCAB) [CAS NO. 14047-09-7] IN HARLAN SPRAGUE-DAWLEY RATS AND B6C3F1 MICE (GAVAGE STUDIES) ...

  41. TR-453: Nickel Subsulfide (CASRN 12035-72-2) in F344 Rats and... 17.9MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr453.pdf

    ... (NTP, 1990) andorallyto2-mercaptobenzothiazole (NTP, 1988) and reserpine (NCI, 1982). ... Bioassay of Reserpine for Carcinogenicity Possible (CAS No. 50-55-5). Technical Report ...

  42. TR-555: 1,2-Dibromo-2,4-dicyanobutane (CASRN 35691-65-7) in F344... 6.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr555.pdf

    1,2-DIbROmO-2,4-DICYANObUTANE (CAS NO. 35691-65-7) IN F344/N RATS AND b6C3F1 mICE (DERmAL STUDIES) NATIONAL TOXICOLOGY PROGRAm P.O. box 12233 Research Triangle Park, NC 27709 June ...

  43. TR-537: Dibromoacetic Acid (CASRN 631-64-1) in F344/N Rats and... 9.3MB

    https://ntp.niehs.nih.gov/go/tr537

    NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF DIBROMOACETIC ACID (CAS NO. 631-64-1) IN F344/N RATS AND B6C3F 1 MICE (DRINKING WATER STUDIES) NATIONAL ...

  44. TR-425: Promethazine Hydrochloride (CASRN 58-33-3) in F344/N... 22.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr425.pdf

    NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF PROMETHAZINE HYDROCHLORIDE (CAS NO. 58-33-3) IN F344/N RATS AND B6C3F MICE 1 (GAVAGE STUDIES) NTP TR 425 NIH ...

  45. TR-455: Codeine (CASRN 76-57-3) in F344 Rats and B6C3F1Mice ... 15.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr455.pdf

    ... Neurogenic signals regulate chromaffin cell proliferation mediate and the mitogenic effect of reserpine in the adult rat adrenal medulla. Lab. Invest. 65, 374-376. Tucker, M. J. ...

  46. TR-542: Cumene (CASRN 98-82-8) in F344/N Rats and B6C3F1 Mice... 9.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr542.pdf

    ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF CUMENE (CAS NO. 98-82-8) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research ...

  47. TR-451: Nickel Oxide (CASRN 1313-99-1) in F344 Rats and B6C3F1... 27.7MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr451.pdf

    ... Public Health Service, National Institutes of Health, Bethesda, MD. National Cancer Institute (NCI) (1982). Bioassay of Reserpine for Possible Carcinogenicity (CAS No. 50-55-5). ...

  48. TR-393: Sodium Fluoride (CASRN 7681-49-4)in F344/N Rats and B6C3F1Mice... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr393.pdf

    NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 393 TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM FLUORIDE (CAS NO. 7681-49-4) IN F344/N RATS AND B6C3Fl MICE (DRINKING ...

  49. Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf

    ... oil fatty acids, reaction prod- ucts with polyamines, alkyl substituted. 721.9470 Reserpine. 721.9480 Resorcinol, formaldehyde sub- stituted carbomonocycle resin. 721.9488 ...

 
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