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Search suggestions for "50-81-7".

  1. CEBS Data Related to L-Ascorbic acid (50-81-7) https://cebs.niehs.nih.gov/cebs/test_article/50-81-7


157 results found for "50-81-7".

  1. TR-247: L-Ascorbic Acid (Vitamin C) (CASRN 50-81-7) in F344/N... 7.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr247.pdf

    OF L-ASCORBIC ACID (VITAMIN C) (CAS NO. 50-81-7) IN F344/N RATS AND B6C3F1 MICE (FEED ... CARCINOGENESIS BIOASSAY OF L-ASCORBIC ACID (VITAMIN C) (CAS NO. 50-81-7) IN F344/N RATS ...

  2. L-Ascorbic acid: Target Organs and Levels of Evidence for TR... 56KB

    https://ntp.niehs.nih.gov/data/tr/200s/tr247levels

    (CASRN 50-81-7) in F344/N Rats and B6C3F1 Mice (Feed Study) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory L-Ascorbic acid 50-81-7 06/16/...

  3. Abstract for TR-247 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr247

    Carcinogenesis Bioassay of L-Ascorbic Acid (Vitamin C) in F344/N Rats and B6C3F1 Mice (Feed Study) CASRN: 50-81-7 Chemical Formula: C6H8O6 Molecular Weight: 176.1232 Synonyms/...

  4. RoC Background Document: Saccharin; Oct. 30-31, 1997 8.9MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/saccharin1_3apps_508.pdf

    BACKGROUND DOCUMENT for SACCHARIN FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors ...

  5. TOX-59: Chloral Hydrate (CASRN 302-17-0) 10.8MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox059.pdf

    59 NTP Technical Report on the Toxicity and Metabolism Studies of Chloral Hydrate (CAS No. 302-17-0) Administered by Gavage to F344/N Rats and B6C3F Mice 1 Frederick A. Beland, ...

  6. Predicting human developmental toxicity of pharmaceuticals using... 510KB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/westtap2016.pdf

    Predicting human developmental toxicity of pharmaceuticals using human embryonic stem cells and metabolomics Paul R. West a, ⁎ , April M. Weir a , Alan M. Smith a , Elizabeth ...

  7. TOWARD VALIDATION OF A HUMAN IN... 1.1MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/egnashposter-2014-wc.pdf

    TOWARD VALIDATION OF A HUMAN IN VITRO ASSAY FOR DEVELOPMENTAL TOXICITY ASSESSMENT Egnash LA, Conard KR, Palmer JA, Smith AM, West PR, Burrier RE, Donley ELR, Kirchner FR Stemina ...

  8. DEVELOPMENT OF A TARGETED BIOMARKER... 3.4MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/palmerposter.pdf

    DEVELOPMENT OF A TARGETED BIOMARKER ASSAY TO PREDICT DEVELOPMENTAL TOXICITY USING INDUCED PLURIPOTENT STEM CELLS Palmer JA, Egnash LA, Smith AM, Conard KR, West PR, Burrier RE, ...

  9. Comparison of devTOX quickPredict Assay With Other Methods 1.0MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/comparisonspreadsheet-508.pdf

    www.stemina.com Author: JA Palmer jpalmer@stemina.com Header Description/Notes Compound Common Compound Name Therapeutic C max (μM) Published human therapeutic Cmax Negative ...

  10. A BIOMARKER BASED DEVELOPMENTAL ... 919KB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/egnashposter-2014-sot.pdf

    A BIOMARKER BASED DEVELOPMENTAL TOXICITY SCREEN USING HUMAN INDUCED PLURIPOTENT STEM CELLS FOR COMPOUND PRIORITIZATION Egnash LA, Palmer JA, Smith AM, Conard KR, West PR, Burrier ...

  11. RoC Profile: Furan; 15th RoC 2021 152KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/furan.pdf

    Furan CAS No. 110-00-9 Reasonably anticipated to be a human carcinogen First listed in the Eighth Report on Carcinogens (1998) O Carcinogenicity Furan is reasonably anticipated to ...

  12. Comparison of the Stemina devTOX quickPredict system with other... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2018-09961/palmer-stemina-spreadsheet.pdf

    Stemina BIOMARKER DISCOVERY Page 1 of 11 www.stemina.com Author: JA Palmer jpalmer@stemina.com Column Header Definitions Header Description/Notes Compound Common Compound Name. ...

  13. Minutes: BSC TRRS; June 16, 1982 632KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1982/june/82june16trrsmin_508.pdf

    Board o f S c i e n t i f i c Counselors N a t i o n a l Toxicology Program Summary M i nu t e s from Peer Reviews o f D r a f t Technical Reports o f Long-Term Carcinogenesis ...

  14. Minutes: BSC TRRS; Nov. 16, 1993 800KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1993/nov/trrs16nov1993mins_508.pdf

    NTP/HEI (Health Effects Institute) Collaborative Ozone Studies and Peer Review of Draft Technical Reports of Long-Term Toxicology and Carcinogenesis Studies and Short Term Toxicity ...

  15. Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf

    SUMMARY OF DATA FOR CHEMICAL SELECTION Dietary Supplements Containing Ephedrine Alkaloids BASIS OF NOMINATION Dietary supplements containing ephedrine alkaloids from herbal ...

  16. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIETHANOLAMINE (CAS NO. 102-71-6) IN B6C3F 1 MICE (DERMAL STUDY) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC ...

  17. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... 1.08 2.35 Aniline 62-53-3 1.07 1.25 EDTA-Na salt 13235-36-4 0.95 0.50 Ascorbic acid 50-81-7 0.49 0.81 Phenol 108-95-2 0.35 0.74 Acrylamide 79-06-1 0.29 0.19 Copper (II) sulfate ...

  18. RR-01: Systematic Literature Review on the Effects of Fluoride... 7.2MB

    https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr01_508.pdf

    NTP ReseaRch RePoRT oN sysTemaTic LiTeRaTuRe Review oN The effecTs of fLuoRide oN LeaRNiNg aNd memoRy iN aNimaL sTudies NTP RR 1 JULY 2016 NTP Research Report on Systematic ...

  19. 15th RoC: Appendix B 103KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_b.pdf

    5.1.1711999471.285.1804289383% X-Anytotx-Content-Type: application/pdf X-Anytotx-Identified-By: command-line Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: 8bit ...

  20. Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel... 6.5MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_panelreportparta_508.pdf

    A - Peer Review of the Draft Background Document on Cobalt-Tungsten Carbide Powders and Hard Metals The Report on Carcinogens (RoC) expert panel for cobalt-tungsten carbide powders ...

  21. TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf

    PROGRAM Technical Report Series No. 388 TOXICOLOGY AND CARCINOGENESIS STUDIES OF ETHYLENE THIOUREA (CAS NO. 96-45-7) IN F344/N RATS AND B6C3F! MICE (FEED STUDIES) U.S. DEPARTMENT ...

  22. TR-462: Molybdenum Trioxide (CASRN 1313-27-5) in F344 Rats and... 25.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr462.pdf

    MOLYBDENUM TRIOXIDE (CAS NO. 1313-27-5) IN F344/N RATS AND B6C3F MICE 1 (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 April 1997 ...

  23. TOX-93: Toxicity Study of Chitosan (CASRN 9012-76-4) Administered... 2.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox093_508.pdf

    STudy of chiToSaN (caSRN 9012-76-4) admiNiSTeRed iN feed To SPRague dawley [cRl:cd(Sd)] RaTS NTP TOX 93 DECEMBER 2017 NTP Technical Report on the Toxicity Study of Chitosan (CASRN ...

  24. Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf

    Background Review Document Frog Embryo Teratogenesis Assay - Xenopus (FETAX) March 10, 2000 Prepared by The National Toxicology Program (NTP) Interagency Center for the Evaluation ...

  25. TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 10.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr509.pdf

    2,4-HEXADIENAL (89% trans,trans isomer, CAS No. 142-83-6; 11% cis,trans isomer) IN F344/N RATS AND B6C3F 1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research ...

  26. TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and B6C3F1Mice... 10.1MB

    https://ntp.niehs.nih.gov/go/tr449

    NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIETHANOLAMINE (CAS NO. 102-71-6) IN F344/N RATS AND B6C3F MICE 1 (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM ...

  27. TR-333: N-Phenyl-2-naphthylamine (CASRN 135-88-6) in F344/N Rats... 9.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr333.pdf

    3 TOXICOLOGY AND CARCINOGENESIS STUDIES O F N-PHENY L-2-NAPHTHYLAMINE (CAS NO. 135-88-6) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...

  28. TR-574: Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1... 13.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr574_508.pdf

    PYROGALLOL (CAS NO. 87-66-1) IN F344/N RATS AND B6C3F1/N MICE (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 February 2013 NTP TR 574 ...

  29. RoC References: Antimony and Other Antimony Compounds; Aug. 17... 830KB

    https://ntp.niehs.nih.gov/ntp/roc/references/antimonyreferences_508.pdf

    ORoC Bibliography for Antimony and Other Antimony Compounds (as of 8/17/2017) 1. Abbaspour A, Najafi M. 2003. Simultaneous determination of Sb(III) and Sb(V) by partial least ...

  30. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... P Clear Evidence P Clear Evidence P Clear Evidence TR-247 06/16/82 L-Ascorbic acid 50-81-7 N No Evidence N No Evidence N No Evidence N No Evidence TR-246 06/23/81 Asbestos, ...

  31. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    Report on Carcinogens Report on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://...

  32. RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB

    https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf

    Cobalt and Cobalt CoMpounds that Release Cobalt ions in ViVo ROC MONOGRAPH 06 APRIL 2016 Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In ...

  33. Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf

    Cobalt and Certain Cobalt Compounds June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental Health ...

  34. Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB

    https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf

    Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In Vivo November 6, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National ...

  35. Literature Search Results: Systematic Review of Fluoride Exposure... 768KB

    https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf

    LITERATURE SEARCH RESULTS FOR THE SYSTEMATIC REVIEW OF FLUORIDE EXPOSURE AND NEURODEVELOPMENTAL AND COGNITIVE HEALTH EFFECTS September 16, 2020 Office of Health Assessment and ...

  36. TR-320: Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1Mice... 11.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr320.pdf

    0 ¥- SERVI(£s (/e ~-.--~~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF ROTENONE (CAS NO. 83-79-4) IN F344/N RATS AND B6C3Ft MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...

  37. TR-501: p,p'-Dichlorodiphenyl Sulfone (CASRN 80-07-9) in F344... 13.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr501.pdf

    NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF p,pN N N N-DICHLORODIPHENYL SULFONE (CAS NO. 80-07-9) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) NATIONAL ...

  38. TR-353: 2,4-Dichlorophenol (CASRN 120-83-2) in F344/N Rats and... 10.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr353.pdf

    3 t TOXICOLOGY AND CARCINOGENESIS STUDIES OF 2,4=DICHLOROPHENOL (CAS NO. 120-83-2) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...

  39. TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB

    https://ntp.niehs.nih.gov/go/tr349

    NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. :349 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TWO PENTACHLOROPHENOL TECHNICAL-GRADE MIXTURES (CAS NO. 87-86-5) IN B6C3FI ...

  40. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... TR-247 PDF (7.62 MB) Carcinogenesis Bioassay of L-Ascorbic Acid (Vitamin C) (CASRN 50-81-7) in F344/N Rats and B6C3F1 Mice (Feed Study) 1983 Technical Report TR-246 PDF (10.08 ...

  41. TR-344: Tetracycline Hydrochloride (CASRN 64-75-5) in F344/N... 10.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr344.pdf

    PROGRAM Technical Report Series No. 344 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TETRACYCLINE HYDROCHLORIDE (CAS NO. 64-75-5) IN F344/N RATS AND B6C3Fi MICE (FEED STUDIES) U.S. ...

  42. CERHR Update on the Reproductive and Developmental Toxicity of... 4.5MB

    https://ntp.niehs.nih.gov/ntp/ohat/phthalates/dehp/dehp-monograph.pdf

    Monograph on the Potential Human Reproductive and Developmental Effects of Di(2-Ethylhexyl) Phthalate (DEHP) November 2006 NIH Publication No. 06 - 4476 iii Table of ConTenTs ...

  43. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-247 PDF (7.62 MB) Carcinogenesis Bioassay of L-Ascorbic Acid (Vitamin C) (CASRN 50-81-7) in F344/N Rats and B6C3F1 Mice (Feed Study) 1983 Long-Term Carcinogenicity TR-246 PDF ...

  44. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... TR-247 PDF (7.62 MB) Carcinogenesis Bioassay of L-Ascorbic Acid (Vitamin C) (CASRN 50-81-7) in F344/N Rats and B6C3F1 Mice (Feed Study) 1983 Technical Report TR-246 PDF (10.08 ...

  45. Draft RoC Monograph Cobalt Appendix: RoC Peer Review; July 22... 1.7MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph_appen.pdf

    Cobalt and Certain Cobalt Compounds Appendices June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental ...

  46. Minutes: BSC; June 12, 2008 280KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2008/june/minutes20080612.pdf

    National Toxicology Program Board of Scientific Counselors June 11-12, 2008 National Institute of Environmental Health Sciences Research Triangle Park, NC Summary Minutes June 11 ...

  47. TR-381: d-Carvone (CASRN 2244-16-8) in B6C3F1Mice (Gavage Studies... 6.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr381.pdf

    1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF d-CARVONE (CAS NO. 2244-16-8) IN B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National ...

  48. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... NA NA 142.27 22.8 100 L- Ascorbic acid 50-81-7 267.73 1.52 11907.1 67.6 3364.3 19.1 ... 125 NA NA 88.12 125 100 L- Ascorbic acid 50-81-7 267.73 1.52 11907.1 67.6 3364.3 19.1 ...

  49. Revised Draft RoC Monograph Cobalt Appendix: RoC Peer Review... 1.7MB

    https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt_append.pdf

    Monograph on Cobalt and Certain Cobalt Compounds That Release Cobalt Ions In Vivo Appendices November 6, 2015 Office of the Report on Carcinogens Division of the National ...

  50. TR-393: Sodium Fluoride (CASRN 7681-49-4)in F344/N Rats and B6C3F1Mice... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr393.pdf

    NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 393 TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM FLUORIDE (CAS NO. 7681-49-4) IN F344/N RATS AND B6C3Fl MICE (DRINKING ...

 
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