-
TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox102_508.pdf
oN T T he oxiciTy STudieS of TRaNS-ReSveRaTRol (caSRN 501-36-0) admiNiSTeRed by GavaGe foR Two weekS oR ThRee moNThS To f344/NTac RaTS, wiSTaR haN [cRl:wi(haN)] RaTS, aNd b6c3f1/N ...
-
Abstract for TOX-102 69KB
https://ntp.niehs.nih.gov/publications/reports/tox/100s/tox102
Toxicity Studies of Trans-resveratrol Administered by Gavage for Two Weeks or Three Months to F344/NTac Rats, Wistar Han [Crl:WI(Han)] Rats, and B6C3F1/N Mice CASRN: 501-36-0 ...
-
Short-Term Toxicity Reports 224KB
https://ntp.niehs.nih.gov/publications/reports/tox
2022 Short-Term Toxicity TOX-102 PDF (2.58 MB) Toxicity Studies of Trans-resveratrol (CASRN 501-36-0) Administered by Gavage for Two Weeks or Three Months to F344/NTac Rats, ...
-
ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf
... Flutamide . Procymidone . Resveratrol . Tamoxifen It should be emphasized that the ... flutamide, procymidone, resveratrol, and tamoxifen) represent eight ...
-
Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... yes +++ ++ # - $2,760 Replacement Resveratrol ER Agonist. + ++ # # $226 * on original ... The replacement for zearalenone is resveratrol. Both substances are moderately active (EC ...
-
TOWARD VALIDATION OF A HUMAN IN... 1.1MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/egnashposter-2014-wc.pdf
... TER 16 Propylene Glycol Environmental NON 300 Ochratoxin A Environmental TER 8 Resveratrol Environmental NON 78 Propiconazole Environmental TER 41 Sorbitol Environmental NON ...
-
Literature Search Results: Systematic Review of Fluoride Exposure... 768KB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf
... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ... Toxicology 200: 169-177. Sharma C, Suhalka P, Bhatnagar M. 2018. Curcumin and resveratrol ...
-
National Institute of Environmental Health Sciences: Suramya... 198KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/suramya
... Comparative toxicokinetics of Trans-resveratrol and its major metabolites in Harlan ... Comparative toxicokinetics of Trans-resveratrol and its major metabolites in Harlan ...
-
NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf
... 2 Progesterone b NEG (1/1) NT NEG 2 Resveratrol POS (2/2) POS (1/1) POS 2 Tamoxifen NEG ... (3/3) POS (1/1) POS (1/1) POS POS 2 Resveratrol POS (3/3) POS (3/3) NEG (1/1) NEG (1/1) ...
-
SOT Annual Meeting: NIEHS and NTP Activitie; March 7-11, 2010 281KB
https://ntp.niehs.nih.gov/ntp/pressctr/mtgs_wkshps/sot_49_activities.pdf
... Metabolomic Analysis of Urine from Resveratrol-Treated Male, Female, and Pregnant ... Toxicokinetics of Resveratrol in Male, Female, Pregnant, and Lactating Wistar Han Rats. ...
-
NTP 2014: Current Directions & Evolving Strategies 3.3MB
https://ntp.niehs.nih.gov/ntp/pubs/currentdirections2014_508.pdf
... The NTP has ongoing studies for black cohosh, dong quai, Echinacea purpurea, evening primrose oil, Garcinia cambogia, gum guggul, green tea, resveratrol, Usnea lichen and valerian. ...
-
State of the DNTP FY 2021; BSC; Dec. 8, 2021 2.7MB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/december/presentations/state_of_dntp_bsc_presentation_508.pdf
... Acetoin and 2,3-Pentanedione, Ionic liquids, Usnic acid, Usnea lichens, trans-Resveratrol, and Aspergillus fumigatus . 2 DART Reports: 2-((1-(4-Phenoxyphenoxy)propan-2- ...
-
Comparison of devTOX quickPredict Assay With Other Methods 1.0MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/comparisonspreadsheet-508.pdf
... NON NON Pyridaben N/A N/A N/A n.d. DT n.d. DT (6) NON (6) DT (5,14) n.d. n.d. DT DT Resveratrol N/A N/A N/A n.d. NON n.d. NON (6) n.d. NON (17) n.d. n.d. DT NON Retinol 2.4 N/A N/A ...
-
Minutes: BSC; Sept. 10-11, 2003 500KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2003/mins2003sept10_508.pdf
... chondroitin sulfate, glucosamine and resveratrol 2. Industrial chemicals - antimony ... lacks functional groups known to be associated with toxicity. o Resveratrol: Dr. ...
-
Documents Provided to the NTP Board of Scientific Counselors... 55.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf
... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ...
-
Minutes: BSC; July 7, 2009 399KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2009/july/minutes20090724.pdf
... unveiled at the Society of Toxicology Meeting held March 15-19, 2009. The first application of the criteria on immunotoxicity studies will be on resveratrol in Winter of 2010. Drs. ...
-
Comparison of the Stemina devTOX quickPredict system with other... 2.1MB
https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2018-09961/palmer-stemina-spreadsheet.pdf
... DT (1) a NON (1) n.d. n.d. n.d. 0.6 n.d. NON │ DT 0.02 0.019 81 Exposure (Daston) Rodent Resveratrol NON n.d. n.d. NON (6) n.d. NON (17) n.d. n.d. 0.38 DT NON N/A N/A N/A ...
-
RR-16: Scoping Review of Paraquat Dichloride Exposure and Parkinson... 2.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr16_508.pdf
... 2017. Effect of resveratrol and tetracycline on the subacute paraquat toxicity in mice. ... 2017. Effect of resveratrol and tetracycline on the subacute paraquat toxicity in mice. ...
-
Literature Search Results for the Systematic Review of Immunotoxicity... 419KB
https://ntp.niehs.nih.gov/ntp/ohat/pfoa_pfos/literaturesearch_201605_508.pdf
... Prepared for: 3M. 216. Vetvicka V, Vetvickova J. 2013. Reversal of perfluorooctanesulfonate-induced immunotoxicity by a glucan- resveratrol-vitamin C combination. Oriental Pharmacy ...
-
Notice: BG1Luc4E2 Cells Are Being Renamed VM7Luc4E2 Cells 1.1MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/bg1luc/bg1luc-vm7luc-june2016-508.pdf
... KC. Induced growth of BG-1 ovarian cancer cells by 17/-estradiol or various endocrine disrupting chemicals was reversed by resveratrol via downregulation of cell cycle progression. ...
-
TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf
... of administration (trans-resveratrol) was available for methylcellulose gavage in rats. ... methylcellulose gavage study of trans-resveratrol: 0/50; all routes (mean ± standard ...
-
Peer Review Panel Report on Evaluation of the LUMI-CELL ER Test... 287KB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edprprept2011.pdf
... that there was discordance among the laboratories for six substances: dicofol, fluoranthene, butylphenol, androstenedione, clomiphene citrat, resveratrol. What about dexamethasone? ...
-
Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... 2022 Short-Term Toxicity TOX-102 PDF (2.58 MB) Toxicity Studies of Trans-resveratrol (CASRN 501-36-0) Administered by Gavage for Two Weeks or Three Months to F344/NTac Rats, ...
-
Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... 2022 Short-Term Toxicity TOX-102 PDF (2.58 MB) Toxicity Studies of Trans-resveratrol (CASRN 501-36-0) Administered by Gavage for Two Weeks or Three Months to F344/NTac Rats, ...
-
TR-595: Sprague Dawley (Hsd:Sprague Dawley SD) Rats Exposed to... 5.6MB
https://ntp.niehs.nih.gov/go/tr595
... For evaluation of the heart lesions, the 12 studies included black cohosh, resveratrol, sodium tungstate dehydrate, tris(chloroisopropyl) phosphate, indole-3-carbinol, ...
-
CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB
https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf
... Five dams/group were exposed to trans-resveratrol, an estrogenic compound found in ... Trans-resveratrol mainly affected locus ceruleus volume and the reproductive system. The ...
-
RoC References: Antimony and Other Antimony Compounds; Aug. 17... 830KB
https://ntp.niehs.nih.gov/ntp/roc/references/antimonyreferences_508.pdf
... S, Gebbia N, Crosta L, Dieli F, Tolomeo M. 2006. Stilbene-based anticancer agents: resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism. ...
-
Monograph: Perfluorooctanoic Acid or Perfluorooctane Sulfonate... 7.8MB
https://ntp.niehs.nih.gov/ntp/ohat/pfoa_pfos/pfoa_pfosmonograph_508.pdf
...uorooctanesulfonate-induced immunotoxicity by a glucan- resveratrol-vitamin C combination. ... sulfonate-induced immunotoxicity by a glucan- resveratrol-vitamin C combination. ...
-
NTP Working Group Report: Draft State of the Science Monograph... 20.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/wgrptbsc20230400.pdf
... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ...
-
NTP Board of Scientific Counselors Working Group Report on the... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/bsc_wg_report_final_version_bsc_approved051623_508.pdf
... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ...
-
NTP Working Group Report: Draft State of the Science Monograph... 9.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/meeting_materials/wgrptbsc20230400_interimver_508.pdf
... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ... supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. ...