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59 results found for "51-75-2".

  1. TR-059: Estradiol Mustard (CASRN 22966-79-6) 4.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr059.pdf

    National Cancer Institute CARCINOGENESIS Technical Report Series No. 59 1978 BIOASSAY OF ESTRADIOL MUSTARD FOR POSSIBLE CARCINOGENICITY CAS No. 22966-79-6 NCI-CG-TR-59 U.S. ...

  2. RoC Profile: Mustard Gas; 15th RoC 2021 121KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/mustardgas.pdf

    Mustard Gas CAS No. 505-60-2 Known to be a human carcinogen First listed in the First Annual Report on Carcinogens (1980) Also known as bis(2-chloroethyl) sulfide Cl H 2 C C H 2 S ...

  3. RoC Profile: Nitrogen Mustard Hydrochloride; 15th RoC 2021 128KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrogenmustardhydrochloride.pdf

    In the literature, the names "nitrogen mustard" and "nitrogen mustard hydrochloride" are used interchangeably. Only nitrogen mustard hydrochloride is produced commercially, so it ...

  4. Estradiol mustard: Target Organs and Levels of Evidence for TR... 57KB

    https://ntp.niehs.nih.gov/data/tr/000s/tr059levels

    0 Estradiol mustard: Target Organs and Levels of Evidence for TR-059 Bioassay of Estradiol Mustard for Possible Carcinogenicity (CASRN 22966-79-6) Chemical (Study Title) CASRN Peer ...

  5. Abstract for TR-59 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr059

    9abs Abstract for TR-59 Bioassay of Estradiol Mustard for Possible Carcinogenicity CASRN: 22966-79-6 Chemical Formula: C42H50Cl4N2O4 Molecular Weight: 788.679 Synonyms/Common ...

  6. Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf

    APPENDICES FOR NTP MONOGRAPH ON DEVELOPMENTAL EFFECTS AND PREGNANCY OUTCOMES ASSOCIATED WITH CANCER CHEMOTHERAPY USE DURING PREGNANCY June 2013 Office of Health Assessment and ...

  7. NTP Monograph: Developmental Effects and Pregnancy Outcomes Associated... 23.8MB

    https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/chemopregnancy_monofinal_508.pdf

    U.S. Department of Health and Human Services National Toxicology Program NTP NTP Monograph Developmental Effects and Pregnancy Outcomes Associated With Cancer Chemotherapy Use ...

  8. Abstract for TR-60 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr060

    60abs Abstract for TR-60 Bioassay of Phenesterin for Possible Carcinogenicity CASRN: 3546-10-9 Chemical Formula: C39H59Cl2NO2 Molecular Weight: 644.8061 Synonyms/Common Names: ...

  9. Abstract for TR-18 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr018

    8abs Abstract for TR-18 Bioassay of 3,3'-Iminobis-1-propanol Dimethanesulfonate (Ester) Hydrochloride (IPD) for Possible Carcinogenicity CASRN: 3458-22-8 Chemical Formula: ...

  10. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    71.1.1711999472.152.1804289383% X-Anytotx-Content-Type: application/pdf X-Anytotx-Identified-By: command-line Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: ...

  11. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    Report on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://ntp.niehs.nih.gov/go/roc ...

  12. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://ntp.niehs.nih.gov/go/roc ...

  13. RoC Profile: Procarbazine and Its Hydrochloride; 15th RoC 2021 130KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/procarbazine.pdf

    Procarbazine and Its Hydrochloride CAS Nos. 671-16-9 and 366-70-1 Reasonably anticipated to be human carcinogens First listed in the Second Annual Report on Carcinogens (1981) H 2 ...

  14. TR-234: Allyl Isothiocyanate (CASRN 57-06-7) in F344/N Rats and... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr234.pdf

    4 CARCINOGENESIS BIOASSAY OF ALLYL ISOTHIOCYANATE (CAS NO. 57-06-7) IN F344/N RATS AND 86C3Fl MICE (GAVAGE STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...

  15. RoC Profile: Chlorambucil; 15th RoC 2021 123KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chlorambucil.pdf

    Chlorambucil CAS No. 305-03-3 Known to be a human carcinogen First listed in the Second Annual Report on Carcinogens (1981) Also known as 4-[p-[bis(2-chloroethyl)amino]phenyl]butyr...

  16. TOX-75: Dimethylaminopropyl Chloride, Hydrochloride (CASRN 5407... 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox075.pdf

    5 NTP Technical Report on the Toxicity Studies of Dimethylaminopropyl Chloride, Hydrochloride (CAS No. 5407-04-5) Administered by Gavage to F344/N Rats and B6C3F 1 Mice Kamal M. ...

  17. DoD Update: ICCVAM Public Forum 2017 831KB

    https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2017/03f-brunell-dod-508.pdf

    An Update from the Department of Defense for the Interagency Coordinating Committee on the Validation of Alternative Methods DISTRIBUTION A. Approved for public release; ...

  18. NTP at the SOT; March 6, 2005 308KB

    https://ntp.niehs.nih.gov/ntp/meetings/2005/ntpsot2_508.pdf

    MARCH 6 * (Morning 11:00-12:00) Society of Toxicology Annual Meeting NTP Presentations March 6-10, 2005 Time Room Presenter Title Abstract ID * Continuing Education Class ...

  19. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    Report on Carcinogens Report on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://...

  20. TR-060: Phenesterin (CASRN 3546-10-9) 4.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr060.pdf

    National Cancer Institute CARCINOGENESIS Technical Report Series No. 60 1978 BIOASSAY OF PHENESTERIN FOR POSSIBLE CARCINOGENICITY CAS No. 3546-10-9 NCI-CG-TR-60 U.S. DEPARTMENT OF ...

  21. TR-018: 3,3'-Iminobis-1-propanol Dimethanesulfonate (Ester) Hydrochlor... 3.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr018.pdf

    8 1978 BIOASSAY OF 3,3'-IMINOBIS-1-PROPANOL DIMETHANESULFONATE (ESTER) HYDROCHLORIDE (IPD) FOR POSSIBLE CARCINOGENICITY CAS No. 3458-22-8 NCI-CG-TR-18 U.S. DEPARTMENT OF HEALTH, ...

  22. ICCVAM 2018 Public Forum Presentation: DOD Update 2.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2018/10-dod.pdf

    An Update from the Department of Defense for the Interagency Coordinating Committee on the Validation of Alternative Methods Emily Reinke, Ph.D., D.A.B.T Biologist, Health Effects ...

  23. Applying In Silico Toxicity Models Across the Tox21 Chemical... 2.6MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-lee-poster.pdf

    Applying In Silico Toxicity Models Across the Tox21 Chemical Universe S. Lee 1 , A. Borrel 2 , K. To 2 , T. Li 3 , Z. Liu 3 , W. Tong 3 , E. Benfenati 4 , A. Roncaglioni 4 , A. ...

  24. RoC Profile: Acetaldehyde; 15th RoC 2021 176KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/acetaldehyde.pdf

    National Toxicology Program, Department of Health and Human Services Report on Carcinogens, Fifteenth Edition For Table of Contents, see home page: http://ntp.niehs.nih.gov/go/roc ...

  25. TR-007: Phenformin (CASRN 114-86-3) 3.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr007.pdf

    Institute CARCINOGENESIS Technical Report Series No.7 January 1977 BIOASSAY OF PHENFORMIN FOR POSSIBLE CARCINOGENICITY CAS No. 114-86-3 NCI-CG-TR-7 U.S. DEPARTMENT OF HEALTH, ...

  26. TOX-48: Allyl Acetate (CASRN 591-87-7), Allyl Alcohol (CASRN... 18.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox048.pdf

    National Toxicology Program Toxicity Report Series Number 48 NTP Technical Report on the Comparative Toxicity Studies of Allyl Acetate, Allyl Alcohol, and Acrolein (CAS Nos. ...

  27. TOX-18: Methyl Ethyl Ketone Peroxide (CASRN 1338-23-4) 4.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox018.pdf

    National Toxicology Program Toxicity Report Series Number 18 NTP Technical Report on Toxicity Studies of JM:ethyl Ethyl Ketone Peroxide (CAS No. 1338-23-4) in Dim.ethyl Phthalate ...

  28. Nomination Background: 2,3-Butanedione (CASRN: 431-03-8) 1.8MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/artificial_butter_flavoring_508be.pdf

    Chemical Information Review Document for Artificial Butter Flavoring and Constituents Diacetyl [CAS No. 431-03-8] and Acetoin [CAS No. 513-86-0] Supporting Nomination for ...

  29. OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201812_508.pdf

    PROTOCOL FOR A SYSTEMATIC REVIEW TO EVALUATE THE EVIDENCE FOR AN ASSOCIATION BETWEEN OCCUPATONAL EXPOSURE TO CANCER CHEMOTHERAPY AGENTS AND ADVERSE HEALTH OUTCOMES Project Leader: ...

  30. Protocol: Sarin Systematic Review; April 2017 1.4MB

    https://ntp.niehs.nih.gov/ntp/ohat/sarin/sr_protocol_508.pdf

    PROTOCOL FOR SYSTEMATIC REVIEW OF LONG-TERM NEUROLOGICAL EFFECTS FOLLOWING ACUTE EXPOSURE TO THE ORGANOPHOSPHORUS NERVE AGENT SARIN April 2017 Office of Health Assessment and ...

  31. NTP Monograph: Systematic Review of Occupational Exposure to... 6.2MB

    https://ntp.niehs.nih.gov/ntp/ohat/oeccaaho/mgraph/occchemo_final20190300_508.pdf

    NTP Monograph on the Systematic Review of Occupational Exposure to Cancer Chemotherapy Agents and Adverse Health Outcomes March 2019 NTP Monograph on the Systematic Review of ...

  32. OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1018KB

    https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201510_508.pdf

    OHAT Evaluation of Occupational Exposure to Chemotherapy and Health Page 1 of 54 PROTOCOL FOR A SYSTEMATIC REVIEW TO EVALUATE THE EVIDENCE FOR AN ASSOCIATION BETWEEN OCCUPATONAL ...

  33. TR-354: Dimethoxane (CASRN 828-00-2) (Commercial Grade) in F344... 11.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr354.pdf

    4 TOXICOLOGY AND CARCINOGENESIS STUDIES OF DIMETHOXANE (CAS NO. 828-00-2) (COMMERCIAL GRADE) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...

  34. TR-584: Indole-3-Carbinol (CASRN 700-06-1) in F344/N Rats and... 4.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr584_508.pdf

    21.1.1712002426.952.1804289383% X-Anytotx-Content-Type: application/pdf X-Anytotx-Identified-By: command-line Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: ...

  35. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    NATIONAL TOXICOLOGY PROGRAM BOARD OF SCIENTIFIC COUNSELORS February 5-6, 1998 Summary Minutes NATIONAL TOXICOLOGY PROGRAM BOARD OF SCIENTIFIC COUNSELORS February 5-6, 1998 Summary ...

  36. GMM-10: Genetically Modified Model Report on Diispropylcarbodiimide... 380KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm10_508.pdf

    STudy of diiSPRoPylcaRbodiiMide (caSRN 693-13-0) iN GeNeTically Modified (fVb TG.ac heMizyGouS) Mice aNd caRciNoGeNiciTy STudy of diiSPRoPylcaRbodiiMide iN GeNeTically Modified ...

  37. TR-427: Turmeric Oleoresin (CASRN 8024-37-1) (Major Component... 16.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr427.pdf

    NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 427 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TURMERIC OLEORESIN (CAS NO. 8024-37-1) (MAJOR COMPONENT 79%-85% CURCUMIN, CAS ...

  38. RR-07: The Preliminary Evaluation of 4-Methylcyclohexylmethanol... 560KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr07_508.pdf

    The PRelimiNaRy evaluaTioN of 4-meThylcyclohexylmeThaNol iN aN iN viTRo humaN aiRway model NTP RR 7 DECEMBER 2018 NTP Research Report on the Preliminary Evaluation of ...

  39. RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf

    Environmental Tobacco Smoke December 2 - 3, 1998 Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. Department of Health ...

  40. Minutes: MPRP; Oct. 1-2, 2012 559KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2012/october/minutes20121002_508.pdf

    National Toxicology Program Draft NTP Monograph on Developmental Effects and Pregnancy Outcomes Associated with Cancer Chemotherapy Use during P regnancy Peer Review Panel Meeting ...

  41. GMM-09: Genetically Modified Model Report on Dicyclohexylcarbodiimide... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm09_508.pdf

    STudieS of dicyclohexylcaRbodiiMide (caSRN 538-75-0) iN f344/N RaTS, b6c3f1 Mice, aNd GeNeTically Modified (fVb TG.ac heMizyGouS) Mice aNd caRciNoGeNiciTy STudy of ...

  42. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    Guidance Document on Using In Vitro Data to Estimate In Vivo Starting Doses for Acute Toxicity Based on Recommendations from an International Workshop Organized by the Interagency ...

  43. TR-242: Diallyl Phthalate (CASRN 131-17-9) in B6C3F1Mice (Gavage... 4.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr242.pdf

    TOXICOLOGY PROGRAM Technical Report Series No. 242 CARCINOGENESIS BIOASSAY OF DIALLYL PHTHALATE (CAS NO. 131-17-9) IN B6C3F1 MICE (GAVAGE STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN ...

  44. RoC Background Document: Thiotepa; Nov. 18-19, 1996 2.3MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/thiotepa1_508.pdf

    FOR THIOTEPA FINAL MARCH 1999 Prepared for the November 18-19, 1996, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by ...

  45. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    9433 Conclusion by Sex/Species Report No. Peer Review Date/Target Organs Substance Name CASRN Male Rats Female Rats Male Mice Female Mice TR-603 01/01/23 Black Cohosh 84776-26-1 NE ...

  46. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    TR-603 PDF (3.02 MB) Toxicology and Carcinogenesis Studies of Black Cohosh Root Extract (CASRN 84776-26-1) Administered by Gavage to Sprague Dawley (Hsd:Sprague Dawley SD) Rats and ...

  47. Minutes: SACATM; Jun. 18-19, 2008 641KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/archives/2008/minutes20080619_508.pdf

    MEETING OF THE SCIENTIFIC ADVISORY COMMITTEE ON ALTERNATIVE TOXICOLOGICAL METHODS JUNE 18 -19, 2008 I. LOCATION OF BACKGROUND MATERIALS/PRESENTATIONS A ND FREQUENTLY USED ...

  48. Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf

    Received via email on October 5, 2016 From: Robert Turesky, University of Minnesota Comments: I wanted to convey to the NTP our recent work, presented at the Division of Chemical ...

  49. Expert Panel Report: Evaluation of In Vitro Ocular Test Methods... 1.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/epreport/ocueprpt.pdf

    DANGER Causes Serious Eye Damage ICCVAM The Interagency Coordinating Committee on the Validation of Alternative Methods NICEATM The National Toxicology Program Interagency Center ...

  50. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ba Toxicology/Carcinogenicity Female scientist looking through a microscope in a laboratory Study Overview Study: Short-term toxicity, long-term carcinogenicity Species: Rats, mice ...

 
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