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ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf
... NEG I I (1/1) NT NT Resveratrol 501-36-0 POS I POS (1/1) I (1/1) NEG (2/3) Spironolactone 52-01-7 NEG NEG NEG (1/1) NT NT Tamoxifen 10540-29-1 POS I I (1/1) I (1/1) POS (1/1) ...
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Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... ER AR Cytotoxicant; recommended by the Expert Panel as a negative control Spironolactone 52-01-7 Lactone, Steroid Pharmaceutical † - AR AR+++ AR+ AR## Y AR agonist and ...
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Update on NICEATM Computational Resources 6.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2021/ppt/2021_sacatm_s4-1_kleinstreuer_v2_508.pdf
... ether meso-Hexestrol Z-Tetrachlorvinphos 17beta-Trenbolone Cyfluthrin Spironolactone Linuron Cycloheximide Estrone 17alpha-Estradiol Reserpine Se&rdl, 2, 2' ,4,4' ...
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NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf
... NEG 4 Reserpine NEG (1/1) NT NEG 4 Spironolactone NEG (1/1) NT NEG Abbreviations: CCi = ... Comprehensive Confirmation Overall 4 Spironolactone POS (1/1) NEG (1/1) NEG a Bisphenol B ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... Propylthiouracil 51-52-5 Pyrimidine; Uracil Pharmaceutical Reserpine 50-55-5 Heterocycle; Yohimban Pharmaceutical Sodium azide 26628-22-8 Organic salt; Azide Spironolactone 52-01-7 ...
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NICEATM Pre-Screen Evaluation of the LUMI-CELL ER Test Method... 595KB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/xdseval2.pdf
... Spironolactone (ICCVAM reported as presumed negative for ER agonist 646 activity and as an ... Spironolactone (ICCVAM reported as presumed negative for ER antagonism 757 activity and as ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... Sigma Sigma Sigma Sigma Powder Powder Powder Powder Powder Reserpine Spironolactone 50-55-5 52-01-7 Heterocycle; Yohimban Steroid, nonphenolic; Pregnene lactone Pharmaceutical ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... Sigma Sigma Sigma Sigma Powder Powder Powder Powder Powder Reserpine Spironolactone 50-55-5 52-01-7 Heterocycle; Yohimban Steroid, nonphenolic; Pregnene lactone Pharmaceutical ...
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RR-17: Scoping Review of Prenatal Exposure to Progestogens and... 960KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr17_508.pdf
... Other synthetic progestogens appear to have anti-androgenic properties (e.g., the pregnane derivatives such as cyproterone acetate, the spironolactone derivative drospirenone), ...
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Background Document: RoC: Riddelliine; 2010 1.7MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/riddelliine_final_508.pdf
... Authors affiliated with National Center for Toxicological Research, AR.) 35. Chung WG, Buhler DR. 1994. The effect of spironolactone treatment on the cytochrome P450-mediated ...
