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Presentation: Incorporating Population Variability and Susceptible... 2.5MB
https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2015/wetmore-508.pdf
... Carbaryl, Difenoconazole, Haloperidol, Tebupirimfos CYP3A4 7 1.0-80.2 Acetochlor, Azoxystrobin, Bensulide, Difenoconazole, Haloperidol, Lovastatin Tebupirimfos CYP3A5 2 ...
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Presentation: Embryonic Vascular Disruption and Adverse Prenatal... 3.0MB
https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/kleinstreuer-508.pdf
... et al. 2014 15 Overt Toxicity: (Body Length) Predominant CVP phenotype: Haloperidol 8.2 µM Haloperidol 2.6 µM Haloperidol 1.4 µM Haloperidol 4.6 µM Haloperidol 0.4% DMSO 4 ...
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Validation of In Vitro Cytotoxicity Test Methods: Test Chemicals 188KB
https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invitrocyto/ivcytodocs/valstdchm.pdf
217.30 SIGMA-ALDRICH G-102 > 99 Glycerol 56-81-5 92.09 SIGMA G5516 99.9 Haloperidol 52-86-8 375.90 SIGMA H1512 99 Hexachlorophene 70-30-4 406.91 SIGMA-ALDRICH 234583-100G ...
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Human stem-cell derived intestinal organoids as a tool to evaluate... 5.4MB
https://ntp.niehs.nih.gov/sites/default/files/2023-12/Wksp_10_Patrik Lundquist_GutModels2023_508.pdf
... Propylparaben Esterase/ Glucoronidation 1.8 To be determined Propranolol CYP2D6/ Glucoronidation 0 None (so far) Haloperidol Glucoronidation CYP2D6 2.7 To be determined Diclofenac ...
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Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... ER+ ER# U/407 weak ER agonist and antagonist; being tested in vivo by OECD Haloperidol 52-86-8 Ketone Pharmaceutical, Veterinary Agent † - - Y IM dopamine D2 receptor ...
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US Strategic Roadmap Goal: Encourage the Use and Adoption of... 3.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2018/september/presentations/02berridge_508.pdf
... (P rilos.ec), pantoprazo le (Protonix) Others A l lopuriool (Zylopfim) Gold therapy Haloperidol (Haldol) Pamidrona te (Aredia) Phenyto in (Dilantin) Quinine (Qualaquin) Ranitid ine ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... Pharmaceutical Genistein 446-72-0 Flavanoid; Isofavone; Phenol Natural product Haloperidol 52-86-8 Butyrophenone; Ketone; Piperazine Pharmaceutical meso-Hexestrol 84-16-2 ...
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In Vitro to In Vivo Extrapolation for Developmental Neurotoxicity... 1.7MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Kreutz-poster.pdf
... 5'5'-Diphenylhydantoin Abamectin Diethylhexyl phthalate Emamectin benzoate Haloperidol Heptachlor Methotrexate o,p-DDT Rotenone S-Bioallethrin Tebuconazole 10 -5 10 -4 10 ...
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Presentation: Setting the Stage: Purpose, Definitions, Scope... 2.1MB
https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/webinar-slides/1-wetmore-07oct2015-fd-508.pdf
... Difenoconazole 0.201 0.49 Renal Insufficiency 3.5 99 Fludioxonil 0.38 4.37 Neonatal 11.5 87 Haloperidol 0.029 0.14 Neonatal 4.9 83 Lovastatin 0.001 0.009 Neonatal 6.5 90 ...
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ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf
... NHK Assay (µg/mL) Glycerol 56-81-5 99.9 Sigma 8.2 4586-100000 7.8 47-101960 Haloperidol 52-86-8 99 Sigma 8.3 0.1-25 7.7 0.188-100 Hexachlorophene 70-30-4 99.2 Sigma-Aldrich 8.1 ...
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Submission of the CertiChem Cell Proliferation Test Method for... 3.1MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/submdoc.pdf
... 99% Sigma Genistein 446-72-0 Flavanoid; Isoflavone; Phenol 1E4-1E12 99% Sigma Haloperidol* 52-86-8 Butyrophenone; Ketone; Piperazine 1E-4 - 1E-12 99% Sigma ICI 182,780 129453-61-8 ...
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NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf
... NT NEG 4 Flutamide NEG (1/1) NT NEG 4 Haloperidol NEG (1/1) NT NEG 4 Ketoconazole NEG (1/... 4 Flutamide POS (1/1) NEG (1/1) NEG 4 Haloperidol NEG (1/1) NEG (1/1) NEG 4 Ketoconazole ...
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ICCVAM Background Review Document (Vol 1): In Vitro Cytotoxicity... 16.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol1_nov2006.pdf
... 491.08 3.79 Organic compound; Amine Haloperidol 128 * MEIC, TESS Pharmaceutical ... In the 50< LD 50 ≤300 category, four substances (haloperidol, caffeine, copper sulfate ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... Haloperidol 4-Hydroxytamoxifen Ketoconazole Linuron 427-51-0 Nitrile; Diphenyl ether; Organochlorine 117-81-7 Phthalate 13311-84-7 Amide; Anilide; Nitrobenzene 52-86-8 ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... Haloperidol 4-Hydroxytamoxifen Ketoconazole Linuron 427-51-0 Nitrile; Diphenyl ether; Organochlorine 117-81-7 Phthalate 13311-84-7 Amide; Anilide; Nitrobenzene 52-86-8 ...
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ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf
... Compound Natural Product, Pharmaceutical 98.8 Sigma-Aldrich Corporation Haloperidol 52-86-8 Ketone Pharmaceutical, Veterinary Agent >99.0 Sigma-Aldrich Corporation ...
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Monograph on Potential Human Reproductive and Developmental Effects... 2.4MB
https://ntp.niehs.nih.gov/ntp/ohat/fluoxetine/fluoxetine_monograph.pdf
... agents (e.g., haloperidol, thioridazine, perphenazine, clozapine, and risperidone). ... also observed with other drugs tested, including diazepam, phenobarbital, and haloperidol. ...
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CERHR Monograph: Amphetamines 4.1MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf
... and.inhibited.by.chlorpromazine,.haloperidol,.and.lithium.carbonate..Amphetamines.co... are.functional.in.rats.at.birth..Haloperidol,.a.D 1 /D 2 .antagonist,.consistently.r...
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OECD Guidance Document 129: Using Cytotoxicity Tests to Estimate... 1.4MB
https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-gd129.pdf
... compound Glycerol 56-81-5 24655 24730 19770 Organic compound; Alcohol Haloperidol 52-86-8 6.13 3.36 330 Organic compound; Ketone Hexachlorophene 70-30-4 4.19 0.029 82 ...
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Nomination Background: 1-Butyl-3-methylimidazolium chloride ... 1.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ionic_liquids_508.pdf
... Usuki et al. (2002) reported that HPTP, the tetrahydropyridinyl dehydration product of haloperidol, may be potentially metabolized to HPP + . HPTP and HPP + were studied in mouse ...
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Literature Search Results: Systematic Review of Fluoride Exposure... 768KB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf
... Toxicol Lett 259: S206-S206. Vulliemoz Y, Woo S, Verosky M, Triner L. 1979. Effect of haloperidol on 5-prime guanylyl imido di phosphate and sodium fluoride induced adenylate ...
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CERHR Monograph: Methylphenidate 11.6MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/methylphenidate/methylphenidatemonograph.pdf
...ons.with.phenytoin.and.antipsychotics.(haloperidol.and.thioridazine). ... Tics. did. not. resolve. after. medication. stopped,.and.haloperidol.was.required,.sug- ...
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CERHR Monograph: Potential Human Reproduction Effects of Styrene 6.0MB
https://ntp.niehs.nih.gov/ntp/ohat/styrene/styrene_monograph.pdf
...ium.ATPase.in.the.microsomal.fraction,.dopamine. receptor.in.corpus.striatum.(using.haloperidol.as.the.ligand),.and.serotonin.receptor.in.frontal.cortex. (using.serotonin.as.the.li...
