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Presentation: ICCVAM Evaluation and Recommendations on Best Practices... 557KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/ocular-present/5-stokesaahe.pdf
... - Administer 0.01 mg/kg buprenorphine subcutaneously to provide a ... Administer Rescue Dose . 0.03 mg/kg buprenorphine and 0.5 mg/kg meloxicam subcutaneously ...
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Report of Ocular Peer Review Panel Meeting (2009) 947KB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/ocularprprept2009.pdf
... Sixty minutes pre-test substance application (TSA) Buprenorphine 0.01 mg/kg by subcutaneous injection (SC) Rationale: Buprenorphine is classified as an opioid agonist-antagonist ...
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Presentation: Alternative Test Methods for Ocular Hazard Assessment... 2.8MB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/ocular-present/12-casestudiesresultssummary.pdf
... Buprenorphine 0.01 mg/kg by subcutaneous injection (SC) to provide a therapeutic level of ... nonsteroidal anti-inflammatory drug - Buprenorphine 0.01 mg/kg by subcutaneous injection ...
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Presentation: In Vitro In Vivo Extrapolation and its Applications... 2.4MB
https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/wksp-ppts/3-2-ke-508.pdf
... Maturation of Biliary Clearance Appears to be Rapid Azithromycin Ceftriaxone Digoxin Buprenorphine Johnson et al Drug Metab Dispos. 2016 © Copyright 2013 Certara, L.P. All rights ...
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ICCVAM Test Method Evaluation Report: Low Volume Eye Test 2.8MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/lvet/tmer-all.pdf
... Pretreatment Analgesia: Buprenorphine 0.01 mg/kg subcutaneous (SC) (60 minutes before test substance application [TSA]). Dr. Sawyer noted that buprenorphine is classified as an ...
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Minutes: SACATM; June 25, 2009 361KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/sacatm/2009/june/minutes20090625.pdf
... Hayes about the Panel's specific recommendation for the use of the analgesic buprenorphine... Nicolaysen asked why the Panel recommended the dose of 0.01 mg/kg buprenorphine, which is ...
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ICCVAM Test Method Evaluation Report: Ocular Hazard Testing Strategy... 4.3MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/amcp/tmer-all.pdf
... Pretreatment Analgesia: Buprenorphine 0.01 mg/kg subcutaneous (SC) (60 minutes before test substance application [TSA]). Dr. Sawyer noted that buprenorphine is classified as an ...
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ICCVAM Test Method Evaluation Report: In Vitro Test Methods for... 34.8MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/invitro-2010/tmer-vol2.pdf
... Pretreatment Analgesia: Buprenorphine 0.01 mg/kg subcutaneous (SC) (60 minutes before test substance application [TSA]). Dr. Sawyer noted that buprenorphine is classified as an ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB
https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf
... to adults, glucuronidation activity was lower for ibuprofen (24- fold), amitriptyline (16-fold), 4-tert-butylphenol (40-fold), estrone (15-fold), and buprenorphine (12-fold). ...